chloroquine has been researched along with Adrenoleukodystrophy in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Adrenoleukodystrophy: An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This disease occurs almost exclusively in the males. Clinical features include the childhood onset of ATAXIA; NEUROBEHAVIORAL MANIFESTATIONS; HYPERPIGMENTATION; ADRENAL INSUFFICIENCY; SEIZURES; MUSCLE SPASTICITY; and DEMENTIA. The slowly progressive adult form is called adrenomyeloneuropathy. The defective gene ABCD1 is located at Xq28, and encodes the adrenoleukodystrophy protein (ATP-BINDING CASSETTE TRANSPORTERS).
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (100.00) | 2.80 |
Authors | Studies |
---|---|
Raas, Q | 1 |
van de Beek, MC | 1 |
Forss-Petter, S | 1 |
Dijkstra, IM | 1 |
Deschiffart, A | 1 |
Freshner, BC | 1 |
Stevenson, TJ | 1 |
Jaspers, YR | 1 |
Nagtzaam, L | 1 |
Wanders, RJ | 1 |
van Weeghel, M | 1 |
Engelen-Lee, JY | 1 |
Engelen, M | 1 |
Eichler, F | 1 |
Berger, J | 1 |
Bonkowsky, JL | 1 |
Kemp, S | 1 |
1 other study available for chloroquine and Adrenoleukodystrophy
Article | Year |
---|---|
Metabolic rerouting via SCD1 induction impacts X-linked adrenoleukodystrophy.
Topics: Adrenoleukodystrophy; Animals; ATP Binding Cassette Transporter, Subfamily D, Member 1; Cell Line; C | 2021 |