Page last updated: 2024-10-24

chloroquine and Adrenoleukodystrophy

chloroquine has been researched along with Adrenoleukodystrophy in 1 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Adrenoleukodystrophy: An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This disease occurs almost exclusively in the males. Clinical features include the childhood onset of ATAXIA; NEUROBEHAVIORAL MANIFESTATIONS; HYPERPIGMENTATION; ADRENAL INSUFFICIENCY; SEIZURES; MUSCLE SPASTICITY; and DEMENTIA. The slowly progressive adult form is called adrenomyeloneuropathy. The defective gene ABCD1 is located at Xq28, and encodes the adrenoleukodystrophy protein (ATP-BINDING CASSETTE TRANSPORTERS).

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Raas, Q1
van de Beek, MC1
Forss-Petter, S1
Dijkstra, IM1
Deschiffart, A1
Freshner, BC1
Stevenson, TJ1
Jaspers, YR1
Nagtzaam, L1
Wanders, RJ1
van Weeghel, M1
Engelen-Lee, JY1
Engelen, M1
Eichler, F1
Berger, J1
Bonkowsky, JL1
Kemp, S1

Other Studies

1 other study available for chloroquine and Adrenoleukodystrophy

ArticleYear
Metabolic rerouting via SCD1 induction impacts X-linked adrenoleukodystrophy.
    The Journal of clinical investigation, 2021, 04-15, Volume: 131, Issue:8

    Topics: Adrenoleukodystrophy; Animals; ATP Binding Cassette Transporter, Subfamily D, Member 1; Cell Line; C

2021