chloroquine has been researched along with Adjuvant Arthritis in 14 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "D-Penicillamine (D-PA), 80-100 mg/kg/day enhanced the early phase of adjuvant arthritis (AA) in rats when it was administered orally for about 4 weeks after the adjuvant injection day, whereas dexamethasone (1 mg/kg/day, p." | 7.66 | [Studies of D-penicillamine (5): effects on rat adjuvant arthritis (author's transl)]. ( Higuchi, S; Kimura, M; Nakaike, S; Ohzeki, M; Otomo, S; Sasajima, M; Tarumoto, Y, 1981) |
| "D-Penicillamine (D-PA), 80-100 mg/kg/day enhanced the early phase of adjuvant arthritis (AA) in rats when it was administered orally for about 4 weeks after the adjuvant injection day, whereas dexamethasone (1 mg/kg/day, p." | 3.66 | [Studies of D-penicillamine (5): effects on rat adjuvant arthritis (author's transl)]. ( Higuchi, S; Kimura, M; Nakaike, S; Ohzeki, M; Otomo, S; Sasajima, M; Tarumoto, Y, 1981) |
| "Rheumatoid arthritis is a chronic inflammatory synovitis that primarily involves peripheral diarthrodial joints." | 2.37 | NIH conference. Rheumatoid arthritis: evolving concepts of pathogenesis and treatment. ( Decker, JL; Haraoui, B; Klippel, JH; Malone, DG; Schrieber, L; Steinberg, AD; Wahl, SM; Wilder, RL, 1984) |
| "Although chloroquine and diclofenac are not cardiovascular drugs, their chronic administration may trigger cardiotoxicity." | 1.56 | Rho-Kinase inhibitors ameliorate diclofenac-induced cardiotoxicity in chloroquine-treated adjuvant arthritic rats. ( Arafa, MH; Atteia, HH; Mohammad, NS, 2020) |
| "Some rabbits with inflicted septic arthritis did not undergo any treatment and served as the control group (n=7)." | 1.35 | Chondroprotective effect of salicylate and chloroquine in pyogenic septic arthritis. ( Cilli, F; Eceviz, E; Eren, A; Ozkan, K; Turhan, Y; Ugutmen, E, 2008) |
| "actions, which can be disclosed in the adjuvant arthritis as well as in the B." | 1.27 | [The testing of long-term antirheumatics in animals]. ( Bekemeier, H; Hirschelmann, R; Weber, M, 1987) |
| "adjuvant arthritis, were found to increase tumour cell 3H-TdR incorporation, compared to macrophages from nonarthritic rats." | 1.26 | Antirheumatic drugs and macrophage function: effects on tumour cell growth in vitro. ( Arrigoni-Martelli, E; Binderup, L; Bramm, E, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Arafa, MH | 1 |
| Mohammad, NS | 1 |
| Atteia, HH | 1 |
| Bhalekar, MR | 1 |
| Upadhaya, PG | 1 |
| Madgulkar, AR | 1 |
| He, Y | 1 |
| Xu, Y | 1 |
| Zhang, C | 1 |
| Gao, X | 1 |
| Dykema, KJ | 1 |
| Martin, KR | 1 |
| Ke, J | 1 |
| Hudson, EA | 1 |
| Khoo, SK | 1 |
| Resau, JH | 1 |
| Alberts, AS | 1 |
| MacKeigan, JP | 1 |
| Furge, KA | 1 |
| Xu, HE | 1 |
| Silva, MA | 1 |
| Ishii-Iwamoto, EL | 1 |
| Bracht, A | 1 |
| Caparroz-Assef, SM | 1 |
| Kimura, E | 1 |
| Cuman, RK | 1 |
| Bersani-Amado, CA | 1 |
| Eren, A | 1 |
| Ugutmen, E | 1 |
| Ozkan, K | 1 |
| Turhan, Y | 1 |
| Eceviz, E | 1 |
| Cilli, F | 1 |
| Decker, JL | 1 |
| Malone, DG | 1 |
| Haraoui, B | 1 |
| Wahl, SM | 1 |
| Schrieber, L | 1 |
| Klippel, JH | 1 |
| Steinberg, AD | 1 |
| Wilder, RL | 1 |
| Cashin, CH | 1 |
| Doherty, NS | 1 |
| Jeffries, BL | 1 |
| Buckland-Wright, JC | 1 |
| Otomo, S | 1 |
| Higuchi, S | 1 |
| Nakaike, S | 1 |
| Tarumoto, Y | 1 |
| Kimura, M | 1 |
| Sasajima, M | 1 |
| Ohzeki, M | 1 |
| Binderup, L | 1 |
| Bramm, E | 1 |
| Arrigoni-Martelli, E | 1 |
| Bekemeier, H | 1 |
| Hirschelmann, R | 1 |
| Weber, M | 1 |
| Hunneyball, IM | 2 |
| Crossley, MJ | 2 |
| Spowage, M | 2 |
| Connolly, KM | 1 |
| Stecher, VJ | 1 |
| Danis, E | 1 |
| Pruden, DJ | 1 |
| LaBrie, T | 1 |
| Pasternak, RD | 1 |
| Marks, RL | 1 |
| Hubbs, SJ | 1 |
| DiPasquale, G | 1 |
1 review available for chloroquine and Adjuvant Arthritis
| Article | Year |
|---|---|
NIH conference. Rheumatoid arthritis: evolving concepts of pathogenesis and treatment.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Chloroquine; Gluc | 1984 |
13 other studies available for chloroquine and Adjuvant Arthritis
| Article | Year |
|---|---|
Rho-Kinase inhibitors ameliorate diclofenac-induced cardiotoxicity in chloroquine-treated adjuvant arthritic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chloroquine; Diclofenac; | 2020 |
Fabrication and efficacy evaluation of chloroquine nanoparticles in CFA-induced arthritic rats using TNF-α ELISA.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Bone and Bones; Carti | 2016 |
Identification of a lysosomal pathway that modulates glucocorticoid signaling and the inflammatory response.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Chloroquine; Cytokines; Glucocorticoids; Inf | 2011 |
Efficiency of combined methotrexate/chloroquine therapy in adjuvant-induced arthritis.
Topics: Acid Phosphatase; Alanine Transaminase; Alkaline Phosphatase; Animals; Arthritis, Experimental; Aspa | 2005 |
Chondroprotective effect of salicylate and chloroquine in pyogenic septic arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Infectious; Cartilage, Articular; | 2008 |
An investigation of the effect of anti-inflammatory and anti-rheumatoid drugs in cell-mediated immune arthritis in guinea-pigs by microfocal radiography.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chloroquine; Disease Models, | 1980 |
[Studies of D-penicillamine (5): effects on rat adjuvant arthritis (author's transl)].
Topics: Administration, Oral; Animals; Arthritis; Arthritis, Experimental; Chloroquine; Dexamethasone; Femal | 1981 |
Antirheumatic drugs and macrophage function: effects on tumour cell growth in vitro.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chloroquine; Female; Levamiso | 1982 |
[The testing of long-term antirheumatics in animals].
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chloroquine; Copper; Delayed- | 1987 |
Pharmacological studies of antigen-induced arthritis in BALB/c mice. II. The effects of second-line antirheumatic drugs and cytotoxic agents on the histopathological changes.
Topics: Animals; Arthritis; Arthritis, Experimental; Chloroquine; Dapsone; Female; Gold Sodium Thiomalate; M | 1986 |
Studies on the effects of pharmacological agents on antigen-induced arthritis in BALB/c mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Arthritis; Arthritis, Experimental; Azat | 1987 |
Alteration of interleukin-1 activity and the acute phase response in adjuvant arthritic rats treated with disease modifying antirheumatic drugs.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experi | 1988 |
Effect of antirheumatic agents on the mitogen response of arthritic rat spleen cells.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Arthritis, Rheumatoid; Chloro | 1985 |