chloroquine has been researched along with Adenocarcinoma Of Kidney in 10 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ursolic acid activates autophagy in renal carcinoma 786-O cells, probably by inhibiting hedgehog signaling pathway activity." | 1.72 | Inhibitory Effect of Ursolic Acid on Proliferation and Migration of Renal Carcinoma Cells and Its Mechanism. ( Lyu, X; Sun, L; Wang, D; Wang, J; Zhang, X, 2022) |
| "Renal cell carcinoma is an aggressive disease often asymptomatic and weakly chemo-radiosensitive." | 1.42 | Antagonistic effects of chloroquine on autophagy occurrence potentiate the anticancer effects of everolimus on renal cancer cells. ( Boccellino, M; Caraglia, M; Desiderio, V; Di Lorenzo, G; Grimaldi, A; Lombardi, A; Misso, G; Pantano, F; Santini, D; Vitiello, PP; Zappavigna, S; Zoccoli, A, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (90.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lyu, X | 1 |
| Zhang, X | 1 |
| Sun, L | 1 |
| Wang, J | 1 |
| Wang, D | 1 |
| Singla, M | 1 |
| Bhattacharyya, S | 1 |
| Makhov, P | 1 |
| Golovine, K | 1 |
| Teper, E | 1 |
| Kutikov, A | 1 |
| Mehrazin, R | 1 |
| Corcoran, A | 1 |
| Tulin, A | 1 |
| Uzzo, RG | 1 |
| Kolenko, VM | 1 |
| Grimaldi, A | 1 |
| Santini, D | 1 |
| Zappavigna, S | 1 |
| Lombardi, A | 1 |
| Misso, G | 1 |
| Boccellino, M | 1 |
| Desiderio, V | 1 |
| Vitiello, PP | 1 |
| Di Lorenzo, G | 1 |
| Zoccoli, A | 1 |
| Pantano, F | 1 |
| Caraglia, M | 1 |
| Kang, JH | 1 |
| Lee, JS | 1 |
| Hong, D | 1 |
| Lee, SH | 1 |
| Kim, N | 1 |
| Lee, WK | 1 |
| Sung, TW | 1 |
| Gong, YD | 1 |
| Kim, SY | 1 |
| Yin, P | 1 |
| Jia, J | 1 |
| Li, J | 1 |
| Song, Y | 1 |
| Zhang, Y | 1 |
| Chen, F | 1 |
| Zhou, L | 1 |
| Yang, H | 1 |
| Bray, K | 1 |
| Mathew, R | 1 |
| Lau, A | 1 |
| Kamphorst, JJ | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Chen, HY | 1 |
| Ghavami, A | 1 |
| Stein, M | 1 |
| DiPaola, RS | 1 |
| Zhang, D | 1 |
| Rabinowitz, JD | 1 |
| White, E | 1 |
| Zhan, YH | 1 |
| Liu, J | 1 |
| Qu, XJ | 1 |
| Hou, KZ | 1 |
| Wang, KF | 1 |
| Liu, YP | 1 |
| Wu, B | 1 |
| Li, H | 1 |
| Jin, X | 1 |
| Zhang, Z | 1 |
| Xing, Y | 1 |
| Kong, X | 1 |
10 other studies available for chloroquine and Adenocarcinoma Of Kidney
| Article | Year |
|---|---|
Inhibitory Effect of Ursolic Acid on Proliferation and Migration of Renal Carcinoma Cells and Its Mechanism.
Topics: Apoptosis; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Chloroquine; Hedg | 2022 |
Autophagy as a potential therapeutic target during epithelial to mesenchymal transition in renal cell carcinoma: An in vitro study.
Topics: Autophagy; Carcinoma, Renal Cell; Cell Culture Techniques; Cell Line, Tumor; Chloroquine; Epithelial | 2017 |
Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death.
Topics: Animals; Apoptosis; Autophagy; Breast Neoplasms; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proli | 2014 |
Antagonistic effects of chloroquine on autophagy occurrence potentiate the anticancer effects of everolimus on renal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Carcinoma, Ren | 2015 |
Renal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagy.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; | 2016 |
ABT-737, a Bcl-2 Selective Inhibitor, and Chloroquine Synergistically Kill Renal Cancer Cells.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosi | 2016 |
The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.
Topics: Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Carcinoma, Renal Cell; Cell Line, T | 2011 |
Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition.
Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Antioxidants; Autophagy; Basal Metab | 2012 |
β-Elemene induces apoptosis in human renal-cell carcinoma 786-0 cells through inhibition of MAPK/ERK and PI3K/Akt/ mTOR signalling pathways.
Topics: Adenine; Apoptosis; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Chloroquine; Extracellul | 2012 |
Inhibition of autophagy enhances apoptosis induced by the PI3K/AKT/mTor inhibitor NVP-BEZ235 in renal cell carcinoma cells.
Topics: Adenine; Apoptosis; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; Chloroquine; Drug Synergism; | 2013 |