chloroquine has been researched along with Acute Kidney Injury in 33 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mortality from sepsis has remained high despite recent advances in supportive and targeted therapies." | 5.35 | Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury. ( Childs, R; Dear, JW; Doi, K; Hu, X; Ito, S; Klinman, DM; Leelahavanichkul, A; Star, RA; Takahashi, Y; Tsunoda, S; Yasuda, H; Yuen, PS; Zhou, H, 2008) |
| " The dosing regimen used in preclinical models of nephrotoxicity may impact the success of therapeutic candidates in clinical trials." | 1.72 | Pharmacological inhibitors of autophagy have opposite effects in acute and chronic cisplatin-induced kidney injury. ( Beverly, LJ; Doll, MA; Feng, JL; Krueger, AM; Orwick, A; Sears, SM; Shah, PP; Siskind, LJ; Vega, AA, 2022) |
| "Chloroquine was administered in doses of 0." | 1.40 | Acute pretreatment with chloroquine attenuates renal I/R injury in rats. ( Basta-Jovanovic, G; Medic, B; Prostran, M; Radojevic Skodric, S; Rovcanin, B; Stojanovic, R; Todorovic, Z, 2014) |
| "A 36-year-old woman with systemic lupus erythematosus was admitted to our hospital with malaise, myalgia, dysphagia, fever, preserved muscle strength, leukocytosis (15,600 cells), and increased creatine kinase of 1,358 IU/L that reached 75,000 IU/L in few days." | 1.37 | Fatal rhabdomyolysis in systemic lupus erythematosus. ( Bonfa, E; da Mota, LM; de Carvalho, JF, 2011) |
| "Mortality from sepsis has remained high despite recent advances in supportive and targeted therapies." | 1.35 | Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury. ( Childs, R; Dear, JW; Doi, K; Hu, X; Ito, S; Klinman, DM; Leelahavanichkul, A; Star, RA; Takahashi, Y; Tsunoda, S; Yasuda, H; Yuen, PS; Zhou, H, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (42.42) | 18.7374 |
| 1990's | 3 (9.09) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 9 (27.27) | 24.3611 |
| 2020's | 5 (15.15) | 2.80 |
| Authors | Studies |
|---|---|
| Sears, SM | 1 |
| Feng, JL | 1 |
| Orwick, A | 1 |
| Vega, AA | 1 |
| Krueger, AM | 1 |
| Shah, PP | 1 |
| Doll, MA | 1 |
| Beverly, LJ | 1 |
| Siskind, LJ | 1 |
| Li, Z | 3 |
| Zhou, L | 3 |
| Du, Y | 1 |
| Li, H | 5 |
| Feng, L | 1 |
| Li, X | 11 |
| Han, X | 1 |
| Liu, H | 2 |
| Minocha, E | 1 |
| Sinha, RA | 1 |
| Jain, M | 1 |
| Chaturvedi, CP | 1 |
| Nityanand, S | 1 |
| Edelstein, CL | 1 |
| Venkatachalam, MA | 1 |
| Dong, Z | 5 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
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| Huang, W | 1 |
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4 reviews available for chloroquine and Acute Kidney Injury
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Cathepsin L in COVID-19: From Pharmacological Evidences to Genetics.
Topics: Acute Kidney Injury; Amantadine; Angiotensin-Converting Enzyme 2; Cathepsin L; Chloroquine; COVID-19 | 2020 |
[Malaria in pregnant women. Presentation of 2 cases and review of the literature].
Topics: Abortion, Spontaneous; Acute Kidney Injury; Adult; Anemia, Hemolytic; Antimalarials; Brain Diseases; | 1982 |
Advances in the treatment of tropical diseases.
Topics: Acute Kidney Injury; Amebiasis; Antimalarials; Ascariasis; Chloroquine; Dexamethasone; Drug Resistan | 1968 |
1 trial available for chloroquine and Acute Kidney Injury
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
29 other studies available for chloroquine and Acute Kidney Injury
| Article | Year |
|---|---|
Pharmacological inhibitors of autophagy have opposite effects in acute and chronic cisplatin-induced kidney injury.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Autophagy; Chloroquine; Cisplatin; Fibrosis; In | 2022 |
Polydatin Attenuates Cisplatin-Induced Acute Kidney Injury via SIRT6-Mediated Autophagy Activation.
Topics: Acute Kidney Injury; Animals; Apoptosis; Autophagy; Chloroquine; Cisplatin; Glucosides; Glutathione; | 2022 |
Amniotic fluid stem cells ameliorate cisplatin-induced acute renal failure through induction of autophagy and inhibition of apoptosis.
Topics: Acute Kidney Injury; Amniotic Fluid; Animals; Apoptosis; Autophagy; bcl-2-Associated X Protein; Bloo | 2019 |
Autophagy inhibition by chloroquine and hydroxychloroquine could adversely affect acute kidney injury and other organ injury in critically ill patients with COVID-19.
Topics: Acute Kidney Injury; Autophagy; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; Crit | 2020 |
Histone deacetylase inhibitors protect against cisplatin-induced acute kidney injury by activating autophagy in proximal tubular cells.
Topics: Acute Kidney Injury; Adenylate Kinase; Animals; Autophagy; Autophagy-Related Protein 7; Chloroquine; | 2018 |
New autophagy reporter mice reveal dynamics of proximal tubular autophagy.
Topics: Acute Kidney Injury; Animals; Autophagy; Cells, Cultured; Chloroquine; Culture Media; Epithelial Cel | 2014 |
Acute pretreatment with chloroquine attenuates renal I/R injury in rats.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Chloroquine; Creatinine; Glomerular Filtration Ra | 2014 |
Autophagy is activated to protect against endotoxic acute kidney injury.
Topics: Acute Kidney Injury; Animals; Autophagy; Autophagy-Related Protein 7; Chloroquine; Cisplatin; Endoto | 2016 |
Neutrophil gelatinase-associated lipocalin worsens ischemia/reperfusion damage of kidney cells by autophagy.
Topics: Acute Kidney Injury; Adenine; Autophagy; Blotting, Western; Cell Line; Cell Survival; Chloroquine; F | 2016 |
Fatal rhabdomyolysis in systemic lupus erythematosus.
Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Antibodies, Antinuclear; Arthritis; Azathioprine; | 2011 |
Severe Plasmodium knowlesi malaria in a tertiary care hospital, Sabah, Malaysia.
Topics: Acute Kidney Injury; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Ethano | 2011 |
Autophagy in proximal tubules protects against acute kidney injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Autophagy; Autophagy-Related Protein 7; Biomarkers; Blood U | 2012 |
[RESOCHIN IN CLINICAL INTERNAL MEDICINE AND ITS POSSIBLE SIDE EFFECTS].
Topics: Acute Kidney Injury; Antimalarials; Arthritis; Arthritis, Rheumatoid; Chloroquine; Collagen Diseases | 1964 |
Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury.
Topics: Acute Disease; Acute Kidney Injury; Animals; Antimalarials; Apoptosis; Blood Urea Nitrogen; Chloroqu | 2008 |
Acute renal failure in Plasmodium malariae infection.
Topics: Acute Kidney Injury; Adult; Animals; Antimalarials; Chloroquine; Female; Humans; Liver Failure; Mala | 2008 |
Intravascular haemolysis and renal insufficiency in children with glucose-6-phosphate dehydrogenase deficiency, following antimalarial therapy.
Topics: Acute Kidney Injury; Child; Child, Preschool; Chloroquine; Erythrocyte Aggregation; Female; Glucosep | 1980 |
Myoglobinuric renal failure following rhabdomyolysis.
Topics: Acute Kidney Injury; Back Injuries; Child; Chloroquine; Female; Humans; Male; Middle Aged; Myoglobin | 1994 |
Rhabdomyolysis associated with malaria tertiana in a patient with myoadenylate deaminase deficiency.
Topics: Acute Kidney Injury; Adult; AMP Deaminase; Chloroquine; Humans; Malaria, Vivax; Male; Rhabdomyolysis | 1993 |
Chloroquine induced haemolysis and acute renal failure in subjects with G-6-PD deficiency.
Topics: Acute Kidney Injury; Child; Chloroquine; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Human | 1978 |
Acute renal failure in severe chloroquine resistant falciparum malaria.
Topics: Acute Kidney Injury; Adult; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; | 1992 |
Peritoneal dialysis in acute renal failure following malaria.
Topics: Acute Kidney Injury; Adult; Bicarbonates; Chloroquine; Folic Acid; Humans; Hydrocortisone; Malaria; | 1967 |
Chloroquine-resistant Falciparum malaria acquired in Vietnam.
Topics: Acute Kidney Injury; Adolescent; Adult; Blood Cell Count; Chloroquine; Dapsone; Drug Resistance, Mic | 1973 |
[Cerebral tropical malaria with blackwater fever. A current diagnostic and therapeutic problem].
Topics: Acute Kidney Injury; Adult; Blackwater Fever; Brain Diseases; Chloroquine; Disseminated Intravascula | 1974 |
Acute falciparum malaria. Complications and treatment.
Topics: Acute Kidney Injury; Brain Diseases; Chloroquine; Coma; Disseminated Intravascular Coagulation; Hepa | 1974 |
[Acute kidney failure and hemolytic anemia caused by erythrocytic G6PD dificit revealed by chloroquine administration].
Topics: Acute Kidney Injury; Anemia, Hemolytic; Chloroquine; Disseminated Intravascular Coagulation; Female; | 1973 |
Nephropathy in Malaria.
Topics: Acute Kidney Injury; Adult; Antimalarials; Anuria; Capillaries; Chloroquine; Creatinine; Dextrans; H | 1968 |
Oliguric renal failure in blackwater fever.
Topics: Acute Kidney Injury; Adolescent; Adult; Anuria; Biopsy; Black People; Chloroquine; Glucosephosphate | 1968 |
Current practice in tropical medicine.
Topics: Acute Kidney Injury; Amebiasis; Amebicides; Chloroquine; Cholera; Drug Resistance, Microbial; Hepati | 1969 |
[Malaria in Rostock].
Topics: Acute Kidney Injury; Africa, Western; Chloroquine; Exchange Transfusion, Whole Blood; Germany, East; | 1971 |