chloroquine has been researched along with Acute Edematous Pancreatitis in 13 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the effects of a weak base, chloroquine, on the trypsinogen processing in cerulein-induced pancreatitis." | 7.72 | The pH modulator chloroquine blocks trypsinogen activation peptide generation in cerulein-induced pancreatitis. ( Makuuchi, M; Matsukura, A; Otani, T; Seyama, Y, 2003) |
| "We have investigated the effect of in vivo chloroquine administration on both secretagogue and diet-induced experimental pancreatitis to determine if raising the pH of cytoplasmic vacuoles in these models of pancreatitis would have a protective effect." | 7.68 | The effect of chloroquine administration on two experimental models of acute pancreatitis. ( Dawra, R; Lerch, MM; Saluja, AK; Saluja, M; Steer, ML, 1993) |
| "We examined the effects of a weak base, chloroquine, on the trypsinogen processing in cerulein-induced pancreatitis." | 3.72 | The pH modulator chloroquine blocks trypsinogen activation peptide generation in cerulein-induced pancreatitis. ( Makuuchi, M; Matsukura, A; Otani, T; Seyama, Y, 2003) |
| "We have investigated the effect of in vivo chloroquine administration on both secretagogue and diet-induced experimental pancreatitis to determine if raising the pH of cytoplasmic vacuoles in these models of pancreatitis would have a protective effect." | 3.68 | The effect of chloroquine administration on two experimental models of acute pancreatitis. ( Dawra, R; Lerch, MM; Saluja, AK; Saluja, M; Steer, ML, 1993) |
| "Pretreatment with chloroquine, a phospholipase A2 inhibitor, led to a inhibition of TXB2 production, whereas 6-keto-PGF1 alpha and PGE2 levels showed a surprising slight elevation in the first 6 h." | 1.27 | Prostanoid imbalance in experimental acute necrotizing pancreatitis in rats. ( Kort, WJ; van Ooijen, B; Vincent, JE; Westbroek, DL; Wilson, JH; Zijlstra, FJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 2 |
| Liu, S | 1 |
| Liu, H | 1 |
| Yang, C | 2 |
| Jiang, A | 1 |
| Wei, H | 1 |
| Sun, D | 1 |
| Cai, Z | 1 |
| Zheng, Y | 2 |
| Hu, T | 1 |
| Cao, H | 1 |
| Zhou, P | 1 |
| He, G | 1 |
| Song, X | 1 |
| Tong, A | 1 |
| Guo, G | 1 |
| Yang, F | 1 |
| Zhang, X | 1 |
| Qian, Z | 1 |
| Qi, X | 1 |
| Zhou, L | 1 |
| Loncle, C | 1 |
| Molejon, MI | 1 |
| Lac, S | 1 |
| Tellechea, JI | 1 |
| Lomberk, G | 1 |
| Gramatica, L | 1 |
| Fernandez Zapico, MF | 1 |
| Dusetti, N | 1 |
| Urrutia, R | 1 |
| Iovanna, JL | 1 |
| Seyama, Y | 1 |
| Otani, T | 3 |
| Matsukura, A | 2 |
| Makuuchi, M | 1 |
| van Dijk, E | 1 |
| Leach, SD | 1 |
| Bilchik, AJ | 1 |
| Karapetian, O | 1 |
| Gorelick, FS | 1 |
| Modlin, IM | 1 |
| Lerch, MM | 1 |
| Saluja, AK | 1 |
| Dawra, R | 1 |
| Saluja, M | 1 |
| Steer, ML | 1 |
| Guillaumes, S | 1 |
| Blanco, I | 1 |
| Villanueva, A | 1 |
| Sans, MD | 1 |
| Clavé, P | 1 |
| Chabás, A | 1 |
| Farré, A | 1 |
| Lluís, F | 1 |
| Skuja, N | 1 |
| van Ooijen, B | 1 |
| Kort, WJ | 1 |
| Zijlstra, FJ | 1 |
| Vincent, JE | 1 |
| Wilson, JH | 1 |
| Westbroek, DL | 1 |
| Buianov, VM | 1 |
| Stupin, IV | 1 |
| Zheltikov, AN | 1 |
| Sherstnev, MP | 1 |
13 other studies available for chloroquine and Acute Edematous Pancreatitis
| Article | Year |
|---|---|
Versatile cationic liposomes for RIP3 overexpression in colon cancer therapy and RIP3 downregulation in acute pancreatitis therapy.
Topics: Animals; Antimalarials; Arginine; Cell Line; Chemotherapy, Adjuvant; Chloroquine; Colonic Neoplasms; | 2020 |
Facile Construction of Chloroquine Containing PLGA-Based pDNA Delivery System for Efficient Tumor and Pancreatitis Targeting in Vitro and in Vivo.
Topics: Animals; Calorimetry, Differential Scanning; Chloroquine; HEK293 Cells; Humans; Lactic Acid; Male; M | 2015 |
The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation.
Topics: Animals; Autophagy; Carcinoma, Ductal; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroqu | 2016 |
The pH modulator chloroquine blocks trypsinogen activation peptide generation in cerulein-induced pancreatitis.
Topics: Animals; Ceruletide; Chloroquine; Enzyme Inhibitors; Fluorescent Antibody Technique; Hydrogen-Ion Co | 2003 |
[Pancreas irritation caused by oxyphenbutazone (Tanderil)].
Topics: Chloroquine; Female; Humans; Oxyphenbutazone; Pancreatitis | 1984 |
Influence of chloroquine on diet-induced pancreatitis.
Topics: Acute Disease; Amylases; Animals; Chloroquine; Choline; Diet; Ethionine; Female; Hydrogen-Ion Concen | 1993 |
The effect of chloroquine administration on two experimental models of acute pancreatitis.
Topics: Acute Disease; Animals; Cathepsin B; Chloroquine; Enzyme Activation; Hydrogen-Ion Concentration; Mal | 1993 |
Chloroquine stabilizes pancreatic lysosomes and improves survival of mice with diet-induced acute pancreatitis.
Topics: Acid Phosphatase; Acute Disease; Amylases; Animals; beta-N-Acetylhexosaminidases; Cathepsin B; Chlor | 1997 |
Chloroquine improves survival of mice with diet-induced acute pancreatitis.
Topics: Acute Disease; Animals; Chloroquine; Diet; Lysosomes; Mice; Pancreatitis; Survival Rate | 1998 |
pH modulator chloroquine prevents diet-induced acute pancreatitis.
Topics: Acute Disease; Animals; Chloroquine; Diet; Hydrogen-Ion Concentration; Mice; Pancreatitis | 2000 |
[Clinical aspects and therapy of chronic pancreatitis].
Topics: 4-Aminobenzoic Acid; Alcoholism; Amylases; Chloroquine; Chronic Disease; Chymotrypsin; Diabetes Mell | 1979 |
Prostanoid imbalance in experimental acute necrotizing pancreatitis in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Chloroquine; Chromones; Dinoprostone; Male; Ne | 1988 |
[Use of dibunol and delagil in the treatment of acute pancreatitis].
Topics: Acute Disease; Administration, Oral; Animals; Antioxidants; Butylated Hydroxytoluene; Chloroquine; D | 1988 |