Page last updated: 2024-10-24

chloroquine and Acute Disease

chloroquine has been researched along with Acute Disease in 123 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"A retrospective study was carried out, over a twelve-year period, of all cases of acute chloroquine poisoning where more than 2 g of chloroquine had been taken."10.17[Effects of diazepam on mortality from acute chloroquine poisoning]. ( Demaziere, J; Gaye, M; Marcoux, L; Ndiaye, M; Saissy, JM; Seck, M; Vitris, M, 1992)
"To evaluate whether chloroquine (CQ) is more effective than meloxicam for treating early musculoskeletal pain and arthritis following acute chikungunya (CHIK) virus infection."9.19Effectiveness of chloroquine and inflammatory cytokine response in patients with early persistent musculoskeletal pain and arthritis following chikungunya virus infection. ( Chopra, A; Saluja, M; Venugopalan, A, 2014)
" In the present study, the efficacies of chloroquine (CQ) or amodiaquine (AQ) in the oral treatment of acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were compared with those of oral treatments with the combination of CQ or AQ with pyrimethamine-sulfadoxine (PS)."9.10A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2002)
"The effects of chloroquine (CQ), amodiaquine (AQ) and CQ plus chlorpheniramine (a histamine H(1) antagonist that reverses CQ resistance in vitro and in vivo) on the disposition of the enlarged liver associated with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were evaluated."9.10The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children. ( Adedeji, AA; Sowunmi, A, 2002)
"To assess the local efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria, children and adults from Sekong province (an area of Laos with a low intensity of transmission) were tested in a 28-day, in-vivo study."9.10The efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria in Laos. ( Brockman, A; Garcia, M; Gastellu, M; Guthmann, JP; Kasparian, S; Legros, D; Nathan, N; Phetsouvanh, R; Phompida, S, 2002)
"The efficacy and kinetics of the combination chloroquine plus sulfadoxine-pyrimethamine (CQ + SP), given sequentially and simultaneously, were investigated in 32 patients with acute uncomplicated Plasmodium falciparum malaria in Palawan Island, the Philippines."9.10Pharmacokinetics of sequential and simultaneous treatment with the combination chloroquine and sulfadoxine-pyrimethamine in acute uncomplicated Plasmodium falciparum malaria in the Philippines. ( Bustos, DG; Diquet, B; Gay, F; Laracas, CJ; Lazaro, JE; Pottier, A; Traore, B, 2002)
"In India, treatment of acute, uncomplicated Plasmodium falciparum malaria is becoming increasingly difficult due to resistance to chloroquine, thus there is a need for new antimalarial drugs."9.09A randomized, double-blind, parallel-group, comparative safety, and efficacy trial of oral co-artemether versus oral chloroquine in the treatment of acute uncomplicated Plasmodium falciparum malaria in adults in India. ( Bhatt, AD; Chogle, AR; Dalvi, SS; Garg, MR; Gathmann, I; Gogtay, NJ; Kshirsagar, NA; Marathe, SN; Moorthy, NS; Mull, R; Sane, SP; Sorabjee, JS; Tilve, GH, 2000)
"The incidence and nature of pruritus induced by chloroquine and halofantrine were studied in 82 patients with acute malaria and in 40 healthy subjects, using a visual analogue scale for quantitating pruritus."9.07Halofantrine-induced pruritus amongst subjects who itch to chloroquine. ( Abila, B; Ambakederemo, AW; Ezeamuzie, IC; Igbigbi, PS; Nwaejike, IN, 1991)
"Poisonings with class I antiarrhythmic drugs and chloroquine are characterized by their severity, related to their membrane-stabilizing effect."8.79[Acute poisoning by class I anti-arrhythmia agents and by chloroquine]. ( Jaeger, A; Liégeon, MN; Raguin, O, 1997)
"In most regions of the world, chloroquine (CQ) has been the standard treatment for Plasmodium vivax malaria for more than 40 years."7.72Efficacy of chloroquine in the treatment of Plasmodium vivax malaria in Turkey. ( Atay, S; Celik, H; Kat, I; Kurcer, MA; Simsek, Z; Topluoglu, S; Zeyrek, FY, 2004)
"To establish the effects of chloroquine on kidney function we monitored renal parameters in age and sex matched control subjects and patients who presented with acute transient fever."7.70Chloroquine influences renal function in rural Zimbabweans with acute transient fever. ( Munjeri, O; Musabayane, CT; Musvibe, A; Osim, EE; Wenyika, J, 1999)
"To obtain a data base of the features of chloroquine poisoning and to assess existing intensive therapy for it."7.69Intensive therapy for chloroquine poisoning. A review of 29 cases. ( McKenzie, AG, 1996)
"Recent experimental findings have suggested that activation of trypsinogen by cathepsin B within acidic pancreatic acinar cell cytoplasmic vacuoles may be a critical early event in both secretagogue and diet-induced pancreatitis."7.68The effect of chloroquine administration on two experimental models of acute pancreatitis. ( Dawra, R; Lerch, MM; Saluja, AK; Saluja, M; Steer, ML, 1993)
"Authors present a simple small bowel surgical wash-out technique that can be used in the treatment of severe chloroquine poisoning."7.68[Small intestine wash-out: technic and indications in acute severe chloroquine poisoning in underdeveloped surgical environments]. ( Achek, S; Gross, GB; Steiner, E; Wiesel, M, 1990)
" The findings indicate that - at least at the dosing regimen used in the present study and among children with acute, uncomplicated, P."6.71A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2003)
"falciparum malaria were treated with either CQ monotherapy (n=120) or the combination of CQ plus three doses of AS (CQ/AS; n=352)."6.71Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes. ( Coleman, R; Drakeley, CJ; Jawara, M; Obisike, U; Pinder, M; Sutherland, CJ; Targett, GA; Walraven, G, 2004)
"A retrospective study was carried out, over a twelve-year period, of all cases of acute chloroquine poisoning where more than 2 g of chloroquine had been taken."6.17[Effects of diazepam on mortality from acute chloroquine poisoning]. ( Demaziere, J; Gaye, M; Marcoux, L; Ndiaye, M; Saissy, JM; Seck, M; Vitris, M, 1992)
"Mortality from sepsis has remained high despite recent advances in supportive and targeted therapies."5.35Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury. ( Childs, R; Dear, JW; Doi, K; Hu, X; Ito, S; Klinman, DM; Leelahavanichkul, A; Star, RA; Takahashi, Y; Tsunoda, S; Yasuda, H; Yuen, PS; Zhou, H, 2008)
"To evaluate whether chloroquine (CQ) is more effective than meloxicam for treating early musculoskeletal pain and arthritis following acute chikungunya (CHIK) virus infection."5.19Effectiveness of chloroquine and inflammatory cytokine response in patients with early persistent musculoskeletal pain and arthritis following chikungunya virus infection. ( Chopra, A; Saluja, M; Venugopalan, A, 2014)
"To assess the local efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria, children and adults from Sekong province (an area of Laos with a low intensity of transmission) were tested in a 28-day, in-vivo study."5.10The efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria in Laos. ( Brockman, A; Garcia, M; Gastellu, M; Guthmann, JP; Kasparian, S; Legros, D; Nathan, N; Phetsouvanh, R; Phompida, S, 2002)
" In the present study, the efficacies of chloroquine (CQ) or amodiaquine (AQ) in the oral treatment of acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were compared with those of oral treatments with the combination of CQ or AQ with pyrimethamine-sulfadoxine (PS)."5.10A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2002)
"The efficacy and kinetics of the combination chloroquine plus sulfadoxine-pyrimethamine (CQ + SP), given sequentially and simultaneously, were investigated in 32 patients with acute uncomplicated Plasmodium falciparum malaria in Palawan Island, the Philippines."5.10Pharmacokinetics of sequential and simultaneous treatment with the combination chloroquine and sulfadoxine-pyrimethamine in acute uncomplicated Plasmodium falciparum malaria in the Philippines. ( Bustos, DG; Diquet, B; Gay, F; Laracas, CJ; Lazaro, JE; Pottier, A; Traore, B, 2002)
"The effects of chloroquine (CQ), amodiaquine (AQ) and CQ plus chlorpheniramine (a histamine H(1) antagonist that reverses CQ resistance in vitro and in vivo) on the disposition of the enlarged liver associated with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were evaluated."5.10The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children. ( Adedeji, AA; Sowunmi, A, 2002)
"In India, treatment of acute, uncomplicated Plasmodium falciparum malaria is becoming increasingly difficult due to resistance to chloroquine, thus there is a need for new antimalarial drugs."5.09A randomized, double-blind, parallel-group, comparative safety, and efficacy trial of oral co-artemether versus oral chloroquine in the treatment of acute uncomplicated Plasmodium falciparum malaria in adults in India. ( Bhatt, AD; Chogle, AR; Dalvi, SS; Garg, MR; Gathmann, I; Gogtay, NJ; Kshirsagar, NA; Marathe, SN; Moorthy, NS; Mull, R; Sane, SP; Sorabjee, JS; Tilve, GH, 2000)
"A randomized, open trial involving 260 Tanzanian children, aged 1-5 years, with acute Plasmodium falciparum malaria was conducted to evaluate the efficacy of the combination antimalarial CGP 56697 (artemether and benflumetol), and to compare it with chloroquine, the standard drug used for malaria treatment in the Kilombero area."5.08Efficacy and safety of CGP 56697 (artemether and benflumetol) compared with chloroquine to treat acute falciparum malaria in Tanzanian children aged 1-5 years. ( Abdulla, S; Beck, HP; Gathmann, I; Hatz, C; Kibatala, P; Mull, R; Royce, C; Schellenberg, D; Tanner, M, 1998)
"The incidence and nature of pruritus induced by chloroquine and halofantrine were studied in 82 patients with acute malaria and in 40 healthy subjects, using a visual analogue scale for quantitating pruritus."5.07Halofantrine-induced pruritus amongst subjects who itch to chloroquine. ( Abila, B; Ambakederemo, AW; Ezeamuzie, IC; Igbigbi, PS; Nwaejike, IN, 1991)
"Poisonings with class I antiarrhythmic drugs and chloroquine are characterized by their severity, related to their membrane-stabilizing effect."4.79[Acute poisoning by class I anti-arrhythmia agents and by chloroquine]. ( Jaeger, A; Liégeon, MN; Raguin, O, 1997)
"A 25 year old man was rushed to the emergency department when he was found unconscious in his room after taking two chloroquine tablets (600 mg base) for fever prescribed by local practitioner."3.78Acute life-threatening methaemoglobinaemia following ingestion of chloroquine. ( Abdali, N; Asif, MS; Rizvi, I; Zaidi, N; Zaman, S, 2012)
"We compared the pharmacokinetics of chloroquine in pregnant and nonpregnant women treated for Plasmodium vivax malaria."3.74Chloroquine pharmacokinetics in pregnant and nonpregnant women with vivax malaria. ( Fernandez, C; Greenwood, BM; Lee, SJ; McGready, R; Nosten, F; Paw, MK; Singhasivanon, P; Stepniewska, K; Thwai, KL; Viladpai-nguen, SJ; Villegas, L; White, NJ, 2008)
"In most regions of the world, chloroquine (CQ) has been the standard treatment for Plasmodium vivax malaria for more than 40 years."3.72Efficacy of chloroquine in the treatment of Plasmodium vivax malaria in Turkey. ( Atay, S; Celik, H; Kat, I; Kurcer, MA; Simsek, Z; Topluoglu, S; Zeyrek, FY, 2004)
"To establish the effects of chloroquine on kidney function we monitored renal parameters in age and sex matched control subjects and patients who presented with acute transient fever."3.70Chloroquine influences renal function in rural Zimbabweans with acute transient fever. ( Munjeri, O; Musabayane, CT; Musvibe, A; Osim, EE; Wenyika, J, 1999)
"To obtain a data base of the features of chloroquine poisoning and to assess existing intensive therapy for it."3.69Intensive therapy for chloroquine poisoning. A review of 29 cases. ( McKenzie, AG, 1996)
"Large doses of chloroquine can cause poisoning."3.69Hypokalaemia related to acute chloroquine ingestion. ( Baud, FJ; Borron, SW; Clemessy, JL; Favier, C; Hantson, PE; Vicaut, E, 1995)
"Recent experimental findings have suggested that activation of trypsinogen by cathepsin B within acidic pancreatic acinar cell cytoplasmic vacuoles may be a critical early event in both secretagogue and diet-induced pancreatitis."3.68The effect of chloroquine administration on two experimental models of acute pancreatitis. ( Dawra, R; Lerch, MM; Saluja, AK; Saluja, M; Steer, ML, 1993)
" Chloroquine, quinine and pyrimethamine, administered after macrogametocytes of Plasmodium falciparum had been found in the blood smear, eliminated the parasites from the peripheral blood, but respiratory failure and treatment-resistant pneumonia occurred, leading to the adult respiratory distress syndrome (Morel stage 4)."3.68[Acute respiratory failure in tropical malaria during pregnancy. Successful treatment using extracorporeal CO2 elimination]. ( Benzing, A; Dippold, W; Grundmann, H; Knolle, P; Meyer zum Büschenfelde, KH; Neurath, M, 1993)
"Authors present a simple small bowel surgical wash-out technique that can be used in the treatment of severe chloroquine poisoning."3.68[Small intestine wash-out: technic and indications in acute severe chloroquine poisoning in underdeveloped surgical environments]. ( Achek, S; Gross, GB; Steiner, E; Wiesel, M, 1990)
"Two soldiers continued weekly prophylaxis with 300 mg chloroquine base on their return to Australia from Papua New Guinea but were not protected against Plasmodium vivax malaria."3.67Plasmodium vivax resistance to chloroquine? ( Davis, DR; Hutton, DC; Rieckmann, KH, 1989)
"Within two months of treatment for falciparum malaria, Plasmodium vivax infections developed in 58 (33%) of 174 patients who had received a quinine or quinidine regimen and in 46 (32%) of 145 patients who had received mefloquine with inpatient follow-up of more than six weeks."3.67High rate of Plasmodium vivax relapse following treatment of falciparum malaria in Thailand. ( Bunnag, D; Chittamas, S; Harinasuta, T; Looareesuwan, S; White, NJ, 1987)
" The findings indicate that - at least at the dosing regimen used in the present study and among children with acute, uncomplicated, P."2.71A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2003)
"falciparum malaria were treated with either CQ monotherapy (n=120) or the combination of CQ plus three doses of AS (CQ/AS; n=352)."2.71Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes. ( Coleman, R; Drakeley, CJ; Jawara, M; Obisike, U; Pinder, M; Sutherland, CJ; Targett, GA; Walraven, G, 2004)
"Malaria is a particularly important problem in the southeast Anatolia region of Turkey."2.41Spontaneous rupture of malarial spleen: two case reports and review of literature. ( Aldemir, M; Büyükbayram, H; Kara , IH; Keles, C; Tacyildiz, IH; Yagmur, Y, 2000)
"1%) were the three main molecules which account for antimalarial self-treatment However the use of these molecules was inappropriate regarding the dosage (41."1.35[Self-medication in the treatment of acute malaria: study based on users of private health drug stores in Ouagadougou, Burkina Faso]. ( Diarra, M; Guissou, IP; Ouédraogo, LT; Somé, IT, 2008)
"Mortality from sepsis has remained high despite recent advances in supportive and targeted therapies."1.35Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury. ( Childs, R; Dear, JW; Doi, K; Hu, X; Ito, S; Klinman, DM; Leelahavanichkul, A; Star, RA; Takahashi, Y; Tsunoda, S; Yasuda, H; Yuen, PS; Zhou, H, 2008)
"A woman with mixed connective tissue disease who developed a reversible acute hepatitis shortly after the initiation of low-dose HCQ is presented."1.34Severe acute hepatitis related to hydroxychloroquine in a woman with mixed connective tissue disease. ( Esteban, MJ; Giner Galvañ, V; Oltra, MR; Redón, J; Rueda, D, 2007)
"Pretreatment with chloroquine, a phospholipase A2 inhibitor, led to a inhibition of TXB2 production, whereas 6-keto-PGF1 alpha and PGE2 levels showed a surprising slight elevation in the first 6 h."1.27Prostanoid imbalance in experimental acute necrotizing pancreatitis in rats. ( Kort, WJ; van Ooijen, B; Vincent, JE; Westbroek, DL; Wilson, JH; Zijlstra, FJ, 1988)
"The clinical presentation and current treatment of malaria are reviewed."1.27Vivax malaria. ( Baker, PB; Dronen, SC, 1986)

Research

Studies (123)

TimeframeStudies, this research(%)All Research%
pre-199050 (40.65)18.7374
1990's33 (26.83)18.2507
2000's29 (23.58)29.6817
2010's8 (6.50)24.3611
2020's3 (2.44)2.80

Authors

AuthorsStudies
Verbrugghen, T1
Cos, P1
Maes, L1
Van Calenbergh, S1
Castro-Cavadía, CJ1
Carmona-Fonseca, J2
Nguépy Keubo, FR1
Mboua, PC1
Djifack Tadongfack, T1
Fokouong Tchoffo, E1
Tasson Tatang, C1
Ide Zeuna, J1
Noupoue, EM1
Tsoplifack, CB1
Folefack, GO1
Kettani, M1
Bandelier, P1
Huo, J1
Li, H4
Yu, D1
Arulsamy, N1
AlAbbad, S1
Sardot, T1
Lekashvili, O1
Decato, D1
Lelj, F1
Alexander Ross, JB1
Rosenberg, E1
Nazir, H1
Muthuswamy, N1
Louis, C1
Jose, S1
Prakash, J1
Buan, MEM1
Flox, C1
Chavan, S1
Shi, X1
Kauranen, P1
Kallio, T1
Maia, G1
Tammeveski, K1
Lymperopoulos, N1
Carcadea, E1
Veziroglu, E1
Iranzo, A1
M Kannan, A1
Arunamata, A1
Tacy, TA1
Kache, S1
Mainwaring, RD1
Ma, M1
Maeda, K1
Punn, R1
Noguchi, S1
Hahn, S3
Iwasa, Y3
Ling, J2
Voccio, JP2
Kim, Y3
Song, J3
Bascuñán, J2
Chu, Y1
Tomita, M1
Cazorla, M1
Herrera, E1
Palomeque, E1
Saud, N1
Hoplock, LB1
Lobchuk, MM1
Lemoine, J1
Li, X10
Henson, MA1
Unsihuay, D1
Qiu, J1
Swaroop, S1
Nagornov, KO1
Kozhinov, AN1
Tsybin, YO1
Kuang, S1
Laskin, J1
Zin, NNINM1
Mohamad, MN1
Roslan, K1
Abdul Wafi, S1
Abdul Moin, NI1
Alias, A1
Zakaria, Y1
Abu-Bakar, N1
Naveed, A1
Jilani, K1
Siddique, AB1
Akbar, M1
Riaz, M1
Mushtaq, Z1
Sikandar, M1
Ilyas, S1
Bibi, I1
Asghar, A1
Rasool, G1
Irfan, M1
Li, XY1
Zhao, S1
Fan, XH1
Chen, KP1
Hua, W1
Liu, ZM1
Xue, XD1
Zhou, B1
Zhang, S2
Xing, YL1
Chen, MA1
Sun, Y1
Neradilek, MB1
Wu, XT1
Zhang, D2
Huang, W1
Cui, Y1
Yang, QQ1
Li, HW1
Zhao, XQ1
Hossein Rashidi, B1
Tarafdari, A1
Ghazimirsaeed, ST1
Shahrokh Tehraninezhad, E1
Keikha, F1
Eslami, B1
Ghazimirsaeed, SM1
Jafarabadi, M1
Silvani, Y1
Lovita, AND1
Maharani, A1
Wiyasa, IWA1
Sujuti, H1
Ratnawati, R1
Raras, TYM1
Lemin, AS1
Rahman, MM1
Pangarah, CA1
Kiyu, A1
Zeng, C2
Du, H1
Lin, D1
Jalan, D1
Rubagumya, F1
Hopman, WM1
Vanderpuye, V1
Lopes, G1
Seruga, B1
Booth, CM1
Berry, S1
Hammad, N1
Sajo, EA1
Okunade, KS1
Olorunfemi, G1
Rabiu, KA1
Anorlu, RI1
Xu, C2
Xiang, Y1
Xu, X1
Zhou, L2
Dong, X1
Tang, S1
Gao, XC1
Wei, CH1
Zhang, RG1
Cai, Q1
He, Y1
Tong, F1
Dong, JH1
Wu, G1
Dong, XR1
Tang, X1
Tao, F1
Xiang, W1
Zhao, Y2
Jin, L1
Tao, H1
Lei, Y1
Gan, H1
Huang, Y1
Chen, Y3
Chen, L3
Shan, A1
Zhao, H2
Wu, M2
Ma, Q1
Wang, J4
Zhang, E1
Zhang, J3
Li, Y5
Xue, F1
Deng, L1
Liu, L2
Yan, Z2
Wang, Y2
Meng, J1
Chen, G2
Anastassiadou, M1
Bernasconi, G1
Brancato, A1
Carrasco Cabrera, L1
Greco, L1
Jarrah, S1
Kazocina, A1
Leuschner, R1
Magrans, JO1
Miron, I1
Nave, S1
Pedersen, R1
Reich, H1
Rojas, A1
Sacchi, A1
Santos, M1
Theobald, A1
Vagenende, B1
Verani, A1
Du, L1
Liu, X1
Ren, Y1
Li, J7
Li, P1
Jiao, Q1
Meng, P1
Wang, F2
Wang, YS1
Wang, C3
Zhou, X2
Wang, W1
Wang, S2
Hou, J1
Zhang, A1
Lv, B1
Gao, C1
Pang, D1
Lu, K1
Ahmad, NH1
Wang, L1
Zhu, J2
Zhang, L2
Zhuang, T1
Tu, J1
Zhao, Z1
Qu, Y1
Yao, H1
Wang, X5
Lee, DF1
Shen, J3
Wen, L1
Huang, G2
Xie, X1
Zhao, Q1
Hu, W1
Zhang, Y4
Wu, X1
Lu, J2
Li, M1
Li, W2
Wu, W1
Du, F1
Ji, H1
Yang, X2
Xu, Z1
Wan, L1
Wen, Q1
Cho, CH1
Zou, C1
Xiao, Z1
Liao, J1
Su, X1
Bi, Z1
Su, Q1
Huang, H1
Wei, Y2
Gao, Y2
Na, KJ1
Choi, H1
Oh, HR1
Kim, YH1
Lee, SB1
Jung, YJ1
Koh, J1
Park, S1
Lee, HJ1
Jeon, YK1
Chung, DH1
Paeng, JC1
Park, IK1
Kang, CH1
Cheon, GJ1
Kang, KW1
Lee, DS1
Kim, YT1
Pajuelo-Lozano, N1
Alcalá, S1
Sainz, B1
Perona, R1
Sanchez-Perez, I1
Logotheti, S1
Marquardt, S1
Gupta, SK1
Richter, C1
Edelhäuser, BAH1
Engelmann, D1
Brenmoehl, J1
Söhnchen, C1
Murr, N1
Alpers, M1
Singh, KP1
Wolkenhauer, O1
Heckl, D1
Spitschak, A1
Pützer, BM1
Liao, Y1
Cheng, J1
Kong, X1
Li, S1
Zhang, M4
Zhang, H1
Yang, T2
Dong, Y1
Xu, Y1
Yuan, Z1
Cao, J1
Zheng, Y1
Luo, Z1
Mei, Z1
Yao, Y1
Liu, Z2
Liang, C1
Yang, H1
Song, Y1
Yu, K1
Zhu, C1
Huang, Z1
Qian, J1
Ge, J1
Hu, J2
Wang, H2
Liu, Y4
Mi, Y1
Kong, H1
Xi, D1
Yan, W1
Luo, X1
Ning, Q1
Chang, X2
Zhang, T2
Wang, Q2
Rathore, MG1
Reddy, K1
Chen, H1
Shin, SH1
Ma, WY1
Bode, AM1
Dong, Z1
Mu, W1
Liu, C3
Gao, F1
Qi, Y1
Lu, H1
Zhang, X4
Cai, X1
Ji, RY1
Hou, Y3
Tian, J2
Shi, Y1
Ying, S1
Tan, M1
Feng, G1
Kuang, Y1
Chen, D1
Wu, D3
Zhu, ZQ1
Tang, HX1
Shi, ZE1
Kang, J1
Liu, Q1
Qi, J2
Mu, J1
Cong, Z1
Chen, S2
Fu, D1
Li, Z2
Celestrin, CP1
Rocha, GZ1
Stein, AM1
Guadagnini, D1
Tadelle, RM1
Saad, MJA1
Oliveira, AG1
Bianconi, V1
Bronzo, P1
Banach, M1
Sahebkar, A1
Mannarino, MR1
Pirro, M1
Patsourakos, NG1
Kouvari, M1
Kotidis, A1
Kalantzi, KI1
Tsoumani, ME1
Anastasiadis, F1
Andronikos, P1
Aslanidou, T1
Efraimidis, P1
Georgiopoulos, A1
Gerakiou, K1
Grigoriadou-Skouta, E1
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Knolle, P1
Grundmann, H1
Dippold, W1
Meyer zum Büschenfelde, KH1
Lerch, MM1
Saluja, AK1
Dawra, R1
Steer, ML1
Taboulet, P1
Hoffman, JR1
Hantson, P1
Barriot, P1
Bismuth, C1
McKenzie, AG1
Lapostolle, F1
Ndiaye, M2
Le Brun, F1
Julien, H1
Galliot, M1
Guillaumes, S1
Blanco, I1
Villanueva, A1
Sans, MD1
Clavé, P1
Chabás, A1
Farré, A1
Lluís, F1
Jaeger, A2
Raguin, O1
Liégeon, MN1
Jahn, J1
Djonlagic, H1
Maschke, S1
Azaroual, N1
Wieruszeski, JM1
Lippens, G1
Imbenotte, M1
Mathieu, D1
Vermeersch, G1
Lhermitte, M1
al-Yaman, F1
Genton, B1
Mokela, D1
Narara, A1
Raiko, A1
Alpers, MP1
Janier, M1
Froidevaux, D1
Lons-Danic, D1
Daniel, F1
Irion, A1
Felger, I1
Abdulla, S2
Smith, T1
Mull, R3
Tanner, M2
Hatz, C2
Beck, HP2
Schellenberg, D1
Gathmann, I2
Kibatala, P1
Royce, C1
Otani, T2
Coëtmeur, D1
Guivarch, G1
Briens, E1
Lopes, C1
Musabayane, CT1
Musvibe, A1
Wenyika, J1
Munjeri, O1
Osim, EE1
Vuong, PN1
Richard, F1
Snounou, G1
Coquelin, F1
Rénia, L1
Gonnet, F1
Chabaud, AG1
Landau, I1
Matsukura, A1
Gogtay, NJ2
Desai, S1
Kadam, VS1
Kamtekar, KD1
Dalvi, SS2
Kshirsagar, NA2
Moorthy, NS1
Garg, MR1
Chogle, AR1
Sorabjee, JS1
Marathe, SN1
Tilve, GH1
Bhatt, AD1
Sane, SP1
Yagmur, Y1
Kara , IH1
Aldemir, M1
Büyükbayram, H1
Tacyildiz, IH1
Keles, C1
Alao, AO1
Dewan, MJ1
Ghalib, HW1
Al-Ghamdi, S1
Akood, M1
Haridi, AE1
Ageel, AA1
Abdalla, RE1
Bustos, DG1
Lazaro, JE1
Gay, F1
Pottier, A1
Laracas, CJ1
Traore, B1
Diquet, B1
Startseva, GG1
Orjih, AU1
Nussenzweig, RS1
Gassner, A1
Pall, H1
Kleinberger, G1
Neumann, E1
Thaler, E1
Pichler, M1
Magometschnigg, D1
Lenzhofer, R1
Thaler, H1
Shirley, JA1
Eykyn, SJ1
Pearson, TC1
Bendtsen, A1
Govaerts-Lepicard, M1
Floman, Y1
Zor, U1
Tempe, JD1
Beissel, J1
Burg, F1
Mantz, JM1
Bunnag, D2
Karbwang, J1
Viravan, C1
Chitamas, S1
Harinasuta, T2
Kempf, J2
Saissy, JM3
Demaziere, J1
Vitris, M1
Seck, M1
Gaye, M1
Marcoux, L1
Salako, LA1
Ezeamuzie, IC1
Igbigbi, PS1
Ambakederemo, AW1
Abila, B1
Nwaejike, IN1
Ochsendorf, FR1
Runne, U1
Bondi, FS1
Siboni, AH1
Hansen, AC1
Bruun-Mogensen, CE1
Nielsen, PF1
Jacobsen, IA1
Steiner, E1
Wiesel, M1
Gross, GB1
Achek, S1
Roberts, PJ1
Cummins, D1
Bainton, AL1
Walshe, KJ1
Fisher-Hoch, SP1
McCormick, JB1
Gribben, JG1
Machin, SJ1
Linch, DC1
Rieckmann, KH2
Davis, DR1
Hutton, DC1
Steffen, R1
Somaini, B1
Chittamas, S1
van Ooijen, B1
Kort, WJ1
Zijlstra, FJ1
Vincent, JE1
Wilson, JH1
Westbroek, DL1
Buianov, VM1
Stupin, IV1
Zheltikov, AN1
Sherstnev, MP1
Weitoft, T1
Piehl-Aulin, K1
Domeij, B1
Baker, PB1
Dronen, SC1
Gupta, MM1
Dang, HS1
Frame, JD1
Baldwin, JM1
Gocke, DJ1
Troup, JM1
Costa Guimarães, A1
Azevedo Vinhaes, L1
Santos Filho, A1
Pericles Esteves, J1
Neves Abreu, W1
Mohr, W1
Clapier, AJ1
Clapier, E1
Knorr, D1
Reuschel, I1
Reinelt, D1
Gruber, G1
Simpson, B1
Jamieson, WS1
Dimond, AH1
Knutsson, F1
Lindstedt, G1
Norrby, A1
Rödjer, S1
Davis, R1
Saif, M1
Simonsen, J1
Beritić, T1
Prpić-Majić, D1
Cifarelli, PS1
Wolfensberger, HR1
Myint, UH1
Win, UK1
Golacka, K1
Janik-Kurylcio, S1
Tomaszewska, Z1
Ciszek, J1
Walczak, J1
Bruce-Chwatt, LJ1
Geddes, TG1
Larkworthy, W1
Klein, E1
Bailey, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers[NCT00367380]Phase 218 participants (Actual)Interventional2006-12-31Completed
Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine (PQ) for the Treatment of Uncomplicated Plasmodium Vivax Infection[NCT02691910]Phase 2/Phase 3204 participants (Actual)Interventional2014-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Infection for P. Vivax

Thick blood smear was performed to patients daily on days 7 to 23, and every other day until day 29. Any prove of P. vivax infection was considered positive and confirmed later by real time polymerase chain reaction (rPCR). (NCT00367380)
Timeframe: Twenty eight days

Interventiondays (Mean)
Group 111
Group 211
Group 39

Reviews

9 reviews available for chloroquine and Acute Disease

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Diagnosis and treatment of the hepatic porphyrias.
    Dermatologic therapy, 2003, Volume: 16, Issue:1

    Topics: Acute Disease; Antimalarials; Chloroquine; Heme; Humans; Photosensitivity Disorders; Porphyrias, Hep

2003
[Acute chloroquine poisoning].
    Presse medicale (Paris, France : 1983), 1996, Oct-19, Volume: 25, Issue:31

    Topics: Acute Disease; Adrenergic Agents; Chloroquine; Combined Modality Therapy; Diazepam; Epinephrine; Hum

1996
[Acute poisoning by class I anti-arrhythmia agents and by chloroquine].
    La Revue du praticien, 1997, Apr-01, Volume: 47, Issue:7

    Topics: Acute Disease; Anti-Arrhythmia Agents; Antirheumatic Agents; Chloroquine; Humans; Poisoning

1997
Spontaneous rupture of malarial spleen: two case reports and review of literature.
    Critical care (London, England), 2000, Volume: 4, Issue:5

    Topics: Acute Disease; Adult; Antimalarials; Chloroquine; Endemic Diseases; Humans; Incidence; Malaria; Male

2000
[Effects of diazepam and incidence of hypoxemia during acute chloroquine poisoning].
    Annales francaises d'anesthesie et de reanimation, 1992, Volume: 11, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Blood Gas Analysis; Chloroquine; Diazepam; Female; Humans; Hypoxia

1992
[Effects of diazepam on mortality from acute chloroquine poisoning].
    Annales francaises d'anesthesie et de reanimation, 1992, Volume: 11, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Chloroquine; Diazepam; Female; Heart Arrest; Humans; Male; Poisoni

1992
[Porphyrias].
    Lijecnicki vjesnik, 1969, Volume: 91, Issue:2

    Topics: Acute Disease; Adenine Nucleotides; Chelating Agents; Chloroquine; Cholestyramine Resin; Chronic Dis

1969
Resistance of P. falciparum to chloroquine in Africa: true or false?
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1970, Volume: 64, Issue:5

    Topics: Acute Disease; Africa; Amodiaquine; Antimalarials; Chloroquine; Proguanil

1970

Trials

20 trials available for chloroquine and Acute Disease

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Effectiveness of chloroquine and inflammatory cytokine response in patients with early persistent musculoskeletal pain and arthritis following chikungunya virus infection.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:2

    Topics: Acute Disease; Alphavirus Infections; Arthritis; Chikungunya Fever; Chloroquine; Cytokines; Disease

2014
The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children.
    Annals of tropical medicine and parasitology, 2002, Volume: 96, Issue:6

    Topics: Acute Disease; Adolescent; Amodiaquine; Antimalarials; Area Under Curve; Child; Child, Preschool; Ch

2002
The efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria in Laos.
    Annals of tropical medicine and parasitology, 2002, Volume: 96, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Fema

2002
A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
    Annals of tropical medicine and parasitology, 2003, Volume: 97, Issue:2

    Topics: Acute Disease; Administration, Oral; Amodiaquine; Analysis of Variance; Antimalarials; Child; Child,

2003
Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes.
    Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:1

    Topics: Acute Disease; Age Factors; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Child; Chil

2004
Predictors of the failure of treatment with chloroquine plus chlorpheniramine, in children with acute, uncomplicated, Plasmodium falciparum malaria.
    Annals of tropical medicine and parasitology, 2005, Volume: 99, Issue:4

    Topics: Acute Disease; Age Factors; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheniramine; D

2005
[Plasmodium vivax malaria: treatment of primary attacks with primaquine, in three different doses, and a fixed dose of chloroquine, Antioquia, Colombia, 2003-2004].
    Biomedica : revista del Instituto Nacional de Salud, 2006, Volume: 26, Issue:3

    Topics: Acute Disease; Adult; Antimalarials; Chloroquine; Colombia; Female; Humans; Malaria, Vivax; Male; Pr

2006
Therapeutic trial of diazepam versus placebo in acute chloroquine intoxications of moderate gravity.
    Intensive care medicine, 1996, Volume: 22, Issue:12

    Topics: Acute Disease; Adult; Anticonvulsants; Antimalarials; Chloroquine; Diazepam; Double-Blind Method; Dr

1996
Distinction of recrudescences from new infections by PCR-RFLP analysis in a comparative trial of CGP 56 697 and chloroquine in Tanzanian children.
    Tropical medicine & international health : TM & IH, 1998, Volume: 3, Issue:6

    Topics: Acute Disease; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chil

1998
Efficacy and safety of CGP 56697 (artemether and benflumetol) compared with chloroquine to treat acute falciparum malaria in Tanzanian children aged 1-5 years.
    Tropical medicine & international health : TM & IH, 1998, Volume: 3, Issue:6

    Topics: Acute Disease; Administration, Oral; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combin

1998
A randomized, parallel-group study in Mumbai (Bombay), comparing chloroquine with chloroquine plus sulfadoxine-pyrimethamine in the treatment of adults with acute, uncomplicated, Plasmodium falciparum malaria.
    Annals of tropical medicine and parasitology, 2000, Volume: 94, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Antimalarials; Chloroquine; Cost of Illness; Cost-Benefit An

2000
A randomized, double-blind, parallel-group, comparative safety, and efficacy trial of oral co-artemether versus oral chloroquine in the treatment of acute uncomplicated Plasmodium falciparum malaria in adults in India.
    The American journal of tropical medicine and hygiene, 2000, Volume: 62, Issue:3

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Antimalarials; Artemether, Lumefantrin

2000
Therapeutic efficacy of chloroquine against uncomplicated, Plasmodium falciparum malaria in south-western Saudi Arabia.
    Annals of tropical medicine and parasitology, 2001, Volume: 95, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Antimalarials; Child; Child, Preschool; Chloroquine

2001
A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
    Annals of tropical medicine and parasitology, 2002, Volume: 96, Issue:3

    Topics: Acute Disease; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Therapy, Combi

2002
Pharmacokinetics of sequential and simultaneous treatment with the combination chloroquine and sulfadoxine-pyrimethamine in acute uncomplicated Plasmodium falciparum malaria in the Philippines.
    Tropical medicine & international health : TM & IH, 2002, Volume: 7, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Antimalarials; Area Under Curve; Child; Chloroquine; Drug Administ

2002
Clinical trials of mefloquine with tetracycline.
    The Southeast Asian journal of tropical medicine and public health, 1992, Volume: 23, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Com

1992
[Effects of diazepam on mortality from acute chloroquine poisoning].
    Annales francaises d'anesthesie et de reanimation, 1992, Volume: 11, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Chloroquine; Diazepam; Female; Heart Arrest; Humans; Male; Poisoni

1992
Evaluation of the relative efficacy of various antimalarial drugs in Nigerian children under five years of age suffering from acute uncomplicated falciparum malaria.
    Annals of tropical medicine and parasitology, 1992, Volume: 86, Issue:1

    Topics: Acute Disease; Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Drug Administration Schedu

1992
Halofantrine-induced pruritus amongst subjects who itch to chloroquine.
    The Journal of tropical medicine and hygiene, 1991, Volume: 94, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Antimalarials; Chloroquine; Drug Eruptions; Drug Hypersensitivity;

1991

Other Studies

96 other studies available for chloroquine and Acute Disease

ArticleYear
Synthesis and evaluation of alpha-halogenated analogues of 3-(acetylhydroxyamino)propylphosphonic acid (FR900098) as antimalarials.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Acute Disease; Animals; Antimalarials; Fosfomycin; Malaria; Mice; Plasmodium berghei; Plasmodium fal

2010
ASSESSMENT OF THE EFFICACY AND SAFETY OF CHLOROQUINE MONOTHERAPY FOR THE TREATMENT OF ACUTE UNCOMPLICATED GESTATIONAL MALARIA CAUSED BY
    Revista colombiana de obstetricia y ginecologia, 2020, Volume: 71, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Antimalarials; Chloroquine; Colombia; Drug Evaluation; Female; Fol

2020
Cav3.2 T-type calcium channels control acute itch in mice.
    Molecular brain, 2020, 09-01, Volume: 13, Issue:1

    Topics: Acute Disease; Animals; Behavior, Animal; Calcium Channels, T-Type; Chloroquine; Female; Histamine;

2020
An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines.
    The American journal of tropical medicine and hygiene, 2013, Volume: 88, Issue:6

    Topics: Acute Disease; Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Disease Mode

2013
Transient lesion in the splenium of the corpus callosum in acute uncomplicated falciparum malaria.
    The American journal of tropical medicine and hygiene, 2014, Volume: 90, Issue:6

    Topics: Acute Disease; Adult; Antimalarials; Artemisinins; Chloroquine; Corpus Callosum; Drug Therapy, Combi

2014
[Self-medication in the treatment of acute malaria: study based on users of private health drug stores in Ouagadougou, Burkina Faso].
    Bulletin de la Societe de pathologie exotique (1990), 2008, Volume: 101, Issue:2

    Topics: Acute Disease; Adult; Antimalarials; Artemisinins; Burkina Faso; Child; Chloroquine; Cross-Sectional

2008
Chloroquine pharmacokinetics in pregnant and nonpregnant women with vivax malaria.
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Area Under Curve; Chloroquine; Female; Hum

2008
Bone marrow aplasia following acute poisoning with chloroquine-proguanil.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:10

    Topics: Acute Disease; Adult; Anemia, Aplastic; Bone Marrow; Chloroquine; Drug Combinations; Female; Humans;

2008
Blood concentrations are better predictors of chioroquine poisoning severity than plasma concentrations: a prospective study with modeling of the concentration/effect relationships.
    Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:9

    Topics: Acute Disease; Adult; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Female; Humans;

2010
Fatal chloroquine poisoning: a rare cause of sudden cardiac arrest.
    Annals of the Academy of Medicine, Singapore, 2011, Volume: 40, Issue:6

    Topics: Acute Disease; Adult; Antimalarials; Arrhythmias, Cardiac; Chloroquine; Death, Sudden, Cardiac; Drug

2011
Acute life-threatening methaemoglobinaemia following ingestion of chloroquine.
    BMJ case reports, 2012, Mar-20, Volume: 2012

    Topics: Acute Disease; Adult; Antimalarials; Chloroquine; Diagnosis, Differential; Enzyme Inhibitors; Fever;

2012
Altered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatment.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Acute Disease; Animals; Chloroquine; Cognition; Female; Fluorescent Antibody Technique; Glycogen Syn

2012
[Chloroquine cardiomyopathy revealed by complete atrio-ventricular block. A case report].
    Archives des maladies du coeur et des vaisseaux, 2002, Volume: 95, Issue:9

    Topics: Acute Disease; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cardiomyopathies; Chloroquine; Fe

2002
[Acute psychosis following treatment with chloroquine for a primo-invasion of Plasmodium vivax malaria].
    Presse medicale (Paris, France : 1983), 2003, Jan-25, Volume: 32, Issue:3

    Topics: Acute Disease; Antimalarials; Chloroquine; Emergencies; Follow-Up Studies; Humans; Malaria, Vivax; M

2003
Point mutations in the pfcrt and pfmdr-1 genes of Plasmodium falciparum and clinical response to chloroquine, among malaria patients from Nigeria.
    Annals of tropical medicine and parasitology, 2003, Volume: 97, Issue:5

    Topics: Acute Disease; Animals; Antimalarials; ATP-Binding Cassette Transporters; Child; Child, Preschool; C

2003
Plasmodium falciparum gametocytaemia in Nigerian children: Peripheral immature gametocytaemia as an indicator of a poor response to chloroquine treatment, and its relationship to molecular determinants of chloroquine resistance.
    Annals of tropical medicine and parasitology, 2003, Volume: 97, Issue:5

    Topics: Acute Disease; Administration, Oral; Adolescent; Animals; Antimalarials; ATP-Binding Cassette Transp

2003
[On a case of malignant endocarditis improved by nivaquine (Libman-Sacks disease)].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1961, Volume: 138

    Topics: Acute Disease; Chloroquine; Endocarditis; Endocarditis, Bacterial; Humans; Lupus Erythematosus, Syst

1961
Efficacy of chloroquine in the treatment of Plasmodium vivax malaria in Turkey.
    Annals of tropical medicine and parasitology, 2004, Volume: 98, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Re

2004
Serum levels of soluble urokinase plasminogen activator receptor is associated with parasitemia in children with acute Plasmodium falciparum malaria infection.
    Parasite immunology, 2004, Volume: 26, Issue:5

    Topics: Acetaminophen; Acute Disease; Amoxicillin; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents;

2004
Predictors of the failure of treatment with chloroquine in children with acute, uncomplicated, Plasmodium falciparum malaria, in an area with high and increasing incidences of chloroquine resistance.
    Annals of tropical medicine and parasitology, 2005, Volume: 99, Issue:6

    Topics: Acute Disease; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Endemic Disease

2005
Severe acute hepatitis related to hydroxychloroquine in a woman with mixed connective tissue disease.
    Clinical rheumatology, 2007, Volume: 26, Issue:6

    Topics: Acute Disease; Adult; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Chloroquine; Fem

2007
Mefloquine-induced mania in a 22-year-old Chinese man.
    Singapore medical journal, 2006, Volume: 47, Issue:6

    Topics: Acute Disease; Adult; Animals; Antimalarials; Bipolar Disorder; Chloroquine; Contraindications; Huma

2006
Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children.
    Memorias do Instituto Oswaldo Cruz, 2006, Volume: 101, Issue:8

    Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheni

2006
Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:5

    Topics: Acute Disease; Acute Kidney Injury; Animals; Antimalarials; Apoptosis; Blood Urea Nitrogen; Chloroqu

2008
Ineffective erythropoiesis in acute human P. falciparum malaria.
    Blut, 1983, Volume: 46, Issue:5

    Topics: Acute Disease; Autoradiography; Bone Marrow Examination; Cell Count; Chloroquine; Erythrocytes; Eryt

1983
Clinical management of acute falciparum malaria in Tanzania.
    Tropical doctor, 1983, Volume: 13, Issue:4

    Topics: Acute Disease; Administration, Oral; Adult; Antimalarials; Child; Chloroquine; Dose-Response Relatio

1983
Landmark article July 20, 1946: Chloroquine for treatment of acute attacks of vivax malaria. By Harry Most, Irving M. London, Charles A. Kane, Paul H. Lavietes, Edmund F. Schroeder and Joseph M. Hayman, Jr.
    JAMA, 1984, May-11, Volume: 251, Issue:18

    Topics: Acute Disease; Chloroquine; History, 20th Century; Humans; Malaria; Plasmodium vivax; United States

1984
Acute clinical malaria (Plasmodium inui) in a cynomolgus monkey (Macaca fascicularis).
    Laboratory animal science, 1983, Volume: 33, Issue:1

    Topics: Acute Disease; Animal Population Groups; Animals; Animals, Wild; Antimalarials; Chloroquine; Disease

1983
Sarcoidosis. Part 2. More on the differential diagnosis. The usual course. Treatments of choice. Prognosis.
    Medical times, 1980, Volume: 108, Issue:6

    Topics: 4-Aminobenzoic Acid; Acute Disease; Adrenal Cortex Hormones; Adult; Alveolitis, Extrinsic Allergic;

1980
[Acute respiratory insufficiency as a complication of falciparum malaria].
    Nederlands tijdschrift voor geneeskunde, 1980, Sep-27, Volume: 124, Issue:39

    Topics: Acute Disease; Chloroquine; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Positive-Pres

1980
Serum and erythrocyte concentrations of chloroquine in patients with acute diarrhoea.
    Annals of tropical medicine and parasitology, 1982, Volume: 76, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Chloroquine; Diarrhea; Erythrocytes; Humans; Intestinal Abso

1982
[Acute intermittent porphyria detected during treatment of malaria with chloroquine].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Sep-01, Volume: 35, Issue:35

    Topics: Acute Disease; Adult; Chloroquine; Diagnosis, Differential; Diagnostic Errors; Humans; Malaria; Male

1980
Acute urticaria associated with shigellosis: a case report.
    Annals of allergy, 1980, Volume: 45, Issue:5

    Topics: Acute Disease; Adult; Chloroquine; Diphenoxylate; Dysentery, Bacillary; Epinephrine; Female; Humans;

1980
Hypokalaemia related to acute chloroquine poisoning.
    Lancet (London, England), 1995, Dec-16, Volume: 346, Issue:8990

    Topics: Acute Disease; Chloroquine; Humans; Hypokalemia; Poisoning; Potassium

1995
Hypokalaemia related to acute chloroquine ingestion.
    Lancet (London, England), 1995, Sep-30, Volume: 346, Issue:8979

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Cause of Death; Chloroquin

1995
Influence of chloroquine on diet-induced pancreatitis.
    Pancreas, 1993, Volume: 8, Issue:1

    Topics: Acute Disease; Amylases; Animals; Chloroquine; Choline; Diet; Ethionine; Female; Hydrogen-Ion Concen

1993
Effect of Plasmodium falciparum malaria on plasma fibrinopeptide-A (FpA) concentration.
    The Central African journal of medicine, 1995, Volume: 41, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Blood Coagulation Tests; Case-Control Studies; Child; Child, Presc

1995
Falciparum malaria in naturally infected human patients: IV--Ultrastructural changes in peripheral white blood cells.
    Annales de parasitologie humaine et comparee, 1993, Volume: 68, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Child; Child, Preschool; Chloroquine; Humans; Leukocytes; Lymphocy

1993
[Acute respiratory failure in tropical malaria during pregnancy. Successful treatment using extracorporeal CO2 elimination].
    Deutsche medizinische Wochenschrift (1946), 1993, Jul-23, Volume: 118, Issue:29-30

    Topics: Acute Disease; Adult; Carbon Dioxide; Cesarean Section; Chloroquine; Drug Therapy, Combination; Extr

1993
The effect of chloroquine administration on two experimental models of acute pancreatitis.
    Gastroenterology, 1993, Volume: 104, Issue:6

    Topics: Acute Disease; Animals; Cathepsin B; Chloroquine; Enzyme Activation; Hydrogen-Ion Concentration; Mal

1993
Treatment of acute chloroquine poisoning: a 5-year experience.
    Critical care medicine, 1996, Volume: 24, Issue:7

    Topics: Acute Disease; Adult; Chloroquine; Combined Modality Therapy; Diazepam; Drug Overdose; Drug Therapy,

1996
Intensive therapy for chloroquine poisoning. A review of 29 cases.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1996, Volume: 86, Issue:5 Suppl

    Topics: Acute Disease; Adolescent; Adult; Antimalarials; Chloroquine; Databases, Factual; Diazepam; Female;

1996
Chloroquine stabilizes pancreatic lysosomes and improves survival of mice with diet-induced acute pancreatitis.
    Pancreas, 1997, Volume: 14, Issue:3

    Topics: Acid Phosphatase; Acute Disease; Amylases; Animals; beta-N-Acetylhexosaminidases; Cathepsin B; Chlor

1997
[Acute chloroquine poisoning].
    Deutsche medizinische Wochenschrift (1946), 1997, Oct-02, Volume: 122, Issue:40

    Topics: Acute Disease; Alcoholic Intoxication; Anticonvulsants; Antimalarials; Chloroquine; Diazepam; Female

1997
Diagnosis of a case of acute chloroquine poisoning using 1H NMR spectroscopy: characterisation of drug metabolites in urine.
    NMR in biomedicine, 1997, Volume: 10, Issue:6

    Topics: Acute Disease; Adult; Chloroquine; Humans; Male; Nuclear Magnetic Resonance, Biomolecular; Poisoning

1997
Resistance of Plasmodium falciparum malaria to amodiaquine, chloroquine and quinine in the Madang Province of Papua New Guinea, 1990-1993.
    Papua and New Guinea medical journal, 1996, Volume: 39, Issue:1

    Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Case-Control Studies; Child; Child, Preschool; C

1996
Acute generalized exanthematous pustulosis due to the combination of chloroquine and proguanil.
    Dermatology (Basel, Switzerland), 1998, Volume: 196, Issue:2

    Topics: Acute Disease; Adult; Animals; Antimalarials; Chloroquine; Drug Eruptions; Drug Therapy, Combination

1998
Chloroquine improves survival of mice with diet-induced acute pancreatitis.
    Pancreas, 1998, Volume: 17, Issue:3

    Topics: Acute Disease; Animals; Chloroquine; Diet; Lysosomes; Mice; Pancreatitis; Survival Rate

1998
[Acute eosinophilic pneumonia. Possible role of chloroquine].
    Revue des maladies respiratoires, 1998, Volume: 15, Issue:5

    Topics: Acute Disease; Antirheumatic Agents; Burns; Chloroquine; Humans; Infant, Newborn; Male; Middle Aged;

1998
Chloroquine influences renal function in rural Zimbabweans with acute transient fever.
    Renal failure, 1999, Volume: 21, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Blood Pressure; Chloroquin

1999
Development of irreversible lesions in the brain, heart and kidney following acute and chronic murine malaria infection.
    Parasitology, 1999, Volume: 119 ( Pt 6)

    Topics: Acute Disease; Animals; Antimalarials; Brain; Chloroquine; Chronic Disease; Kidney; Malaria; Mice; M

1999
pH modulator chloroquine prevents diet-induced acute pancreatitis.
    Pancreas, 2000, Volume: 20, Issue:4

    Topics: Acute Disease; Animals; Chloroquine; Diet; Hydrogen-Ion Concentration; Mice; Pancreatitis

2000
Psychiatric complications of malaria: a case report.
    International journal of psychiatry in medicine, 2001, Volume: 31, Issue:2

    Topics: Acute Disease; Adult; Antimalarials; Brain; Chloroquine; Chronic Disease; Humans; Malaria, Falciparu

2001
[Clinico-immunological evaluation of the effectiveness of delagil and homologous gamma globulin (normal immunoglobulin) in viral hepatitis].
    Vrachebnoe delo, 1978, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Chloroquine; Drug Evaluation; gamma-Globulins; Hepatitis, Vi

1978
Plasmodium berghei: suppression of antibody response to sporozoite stage by acute blood stage infection.
    Clinical and experimental immunology, 1979, Volume: 38, Issue:1

    Topics: Acute Disease; Animals; Antibody Formation; Antibody Specificity; Apicomplexa; Chloroquine; Cricetin

1979
[Course and intensive treatment of acute falciparum malaria (author's transl)].
    Wiener klinische Wochenschrift, 1979, Jan-19, Volume: 91, Issue:2

    Topics: Acute Disease; Adult; Chloroquine; Diagnosis, Differential; Dose-Response Relationship, Drug; Enceph

1979
Chloroquine-resistant falciparum malaria in a Bangladeshi girl with acute lymphoblastic leukaemia.
    British medical journal, 1979, Oct-06, Volume: 2, Issue:6194

    Topics: Acute Disease; Child; Chloroquine; Drug Resistance, Microbial; Female; Humans; Leukemia, Lymphoid; M

1979
[Acute chloroquine poisoning with complete recovery].
    Ugeskrift for laeger, 1979, Jul-16, Volume: 141, Issue:29

    Topics: Acute Disease; Adult; Chloroquine; Humans; Male; Methods

1979
[Seriousness factors in acute poisoning].
    Bruxelles medical, 1978, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Belgium; Child; Child, Preschool; Chloroquine; Colchi

1978
Mechanism of steroid action in inflammation: inhibition of prostaglandin synthesis and release.
    Prostaglandins, 1976, Volume: 12, Issue:3

    Topics: Acute Disease; Aldosterone; Animals; Anti-Inflammatory Agents; Arthritis; Chloroquine; Corticosteron

1976
[Acute intoxications due to cardiotropic drugs : ajmaline, chloroquine and digitalin].
    Minerva medica, 1976, Dec-15, Volume: 67, Issue:61

    Topics: Acute Disease; Adolescent; Adult; Ajmaline; Chloroquine; Coma; Digitalis Glycosides; Female; Humans;

1976
[Hypoxemia in acute benign chloroquine intoxication].
    Presse medicale (Paris, France : 1983), 1991, Mar-16, Volume: 20, Issue:10

    Topics: Acute Disease; Chloroquine; Gastric Lavage; Humans; Hyperbaric Oxygenation; Hypoxia

1991
[Subacute chloroquine overdosage].
    Deutsche medizinische Wochenschrift (1946), 1991, Oct-04, Volume: 116, Issue:40

    Topics: Accommodation, Ocular; Acute Disease; Adult; Chloroquine; Drug Overdose; Hair Color; Heliotherapy; H

1991
Childhood cerebral malaria in Ibadan.
    Journal of tropical pediatrics, 1991, Volume: 37, Issue:2

    Topics: Acute Disease; Child; Child, Preschool; Chloroquine; Coma; Female; Humans; Infant; Malaria; Male; Ni

1991
[Treatment of acute chloroquine poisoning].
    Ugeskrift for laeger, 1990, Apr-02, Volume: 152, Issue:14

    Topics: Acute Disease; Adolescent; Chloroquine; Diazepam; Dobutamine; Female; Humans; Respiration, Artificia

1990
[Small intestine wash-out: technic and indications in acute severe chloroquine poisoning in underdeveloped surgical environments].
    Annales de chirurgie, 1990, Volume: 44, Issue:5

    Topics: Acute Disease; Chloroquine; Enema; Humans; Poisoning; Saline Solution, Hypertonic; Urinary Catheteri

1990
Plasma from patients with severe Lassa fever profoundly modulates f-met-leu-phe induced superoxide generation in neutrophils.
    British journal of haematology, 1989, Volume: 73, Issue:2

    Topics: Acute Disease; Adenosine Diphosphate; Cells, Cultured; Chloroquine; Humans; Kinetics; Lassa Fever; N

1989
Plasmodium vivax resistance to chloroquine?
    Lancet (London, England), 1989, Nov-18, Volume: 2, Issue:8673

    Topics: Acute Disease; Animals; Antimalarials; Blood Specimen Collection; Chloroquine; Dapsone; Drug Adminis

1989
Severe cutaneous adverse reactions to sulfadoxine-pyrimethamine in Switzerland.
    Lancet (London, England), 1986, Mar-15, Volume: 1, Issue:8481

    Topics: Acute Disease; Antimalarials; Chloroquine; Drug Combinations; Drug Eruptions; Humans; Pyrimethamine;

1986
High rate of Plasmodium vivax relapse following treatment of falciparum malaria in Thailand.
    Lancet (London, England), 1987, Nov-07, Volume: 2, Issue:8567

    Topics: Acute Disease; Adolescent; Adult; Animals; Antimalarials; Chloroquine; Female; Follow-Up Studies; Hu

1987
Prostanoid imbalance in experimental acute necrotizing pancreatitis in rats.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Chloroquine; Chromones; Dinoprostone; Male; Ne

1988
[Use of dibunol and delagil in the treatment of acute pancreatitis].
    Vestnik khirurgii imeni I. I. Grekova, 1988, Volume: 141, Issue:12

    Topics: Acute Disease; Administration, Oral; Animals; Antioxidants; Butylated Hydroxytoluene; Chloroquine; D

1988
[Acute gait disorders--an adverse effect of chloroquine].
    Lakartidningen, 1988, Apr-20, Volume: 85, Issue:16

    Topics: Acute Disease; Aged; Chloroquine; Female; Gait; Humans; Neuromuscular Diseases

1988
Vivax malaria.
    The American journal of emergency medicine, 1986, Volume: 4, Issue:1

    Topics: Acute Disease; Adult; Cambodia; Chloroquine; Emergencies; Emigration and Immigration; Female; Fluid

1986
Acute cerebellar ataxia in adults (report of two cases).
    Journal of postgraduate medicine, 1986, Volume: 32, Issue:2

    Topics: Acute Disease; Adult; Age Factors; Cerebellar Ataxia; Chloroquine; Humans; Malaria; Male; Prednisolo

1986
Lassa fever, a new virus disease of man from West Africa. I. Clinical description and pathological findings.
    The American journal of tropical medicine and hygiene, 1970, Volume: 19, Issue:4

    Topics: Acute Disease; Adult; Aged; Autopsy; Back Pain; Blood; Blood Cell Count; Chloroquine; Edema; Female;

1970
Acute suppurative amebic pericarditis.
    The American journal of cardiology, 1974, Volume: 34, Issue:1

    Topics: Acute Disease; Amebiasis; Blood Pressure; Cardiac Catheterization; Cardiac Tamponade; Cardiomegaly;

1974
[Clinical aspects of amebic dysentery].
    Gastroenterologische Fortbildungskurse fur die Praxis, 1973, Volume: 3

    Topics: Acute Disease; Antibody Formation; Chloroquine; Complement Fixation Tests; Dysentery, Amebic; Emetin

1973
[Treatment and prognosis of nephrotic syndrome in childhood-follow-up studies of the years 1930 to 1970 (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1974, Volume: 122, Issue:10

    Topics: Acute Disease; Anti-Bacterial Agents; Biopsy; Child, Preschool; Chloroquine; Dietary Proteins; Diure

1974
[Diagnosis and course evaluation in rheumatic fever].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Sep-15, Volume: 29, Issue:18

    Topics: Acute Disease; Adult; Aminopyrine; Child; Chloroquine; Humans; Penicillins; Phenylbutazone; Predniso

1974
Sulphadoxine and pyrimethamine as treatment for acute Plasmodium falciparum malaria.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1972, Volume: 66, Issue:2

    Topics: Acute Disease; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Military Medicine; Pl

1972
[A case of chloroquine-induced porphyrinuria].
    Lakartidningen, 1973, Apr-11, Volume: 70, Issue:15

    Topics: Acute Disease; Arthritis, Rheumatoid; Chloroquine; Female; Humans; Middle Aged; Porphyrias; Porphyri

1973
Spontaneous rupture of the pathological spleen in malaria.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Oct-06, Volume: 47, Issue:39

    Topics: Acute Disease; Adult; Chloroquine; Female; Humans; Malaria; Rupture, Spontaneous; Splenectomy; Splen

1973
Treatment of amoebiasis.
    The Journal of the Egyptian Public Health Association, 1973, Volume: 48, Issue:3

    Topics: Acute Disease; Amebiasis; Anti-Bacterial Agents; Chloroquine; Chronic Disease; Dysentery, Amebic; Eg

1973
[Acute chloroquine poisoning with a fatal course].
    Ugeskrift for laeger, 1974, Jun-24, Volume: 136, Issue:26

    Topics: Acute Disease; Arthritis, Rheumatoid; Chloroquine; Female; Humans; Middle Aged; Time Factors

1974
The liver in acute amebic colitis.
    The American journal of gastroenterology, 1969, Volume: 52, Issue:5

    Topics: Acute Disease; Adult; Amebiasis; Biopsy; Chloroquine; Complement Fixation Tests; Diarrhea; Dysentery

1969
[Therapy of sarcoidosis].
    Der Internist, 1969, Volume: 10, Issue:8

    Topics: Acute Disease; Chloroquine; Chronic Disease; Female; Glucocorticoids; Humans; Oxyphenbutazone; Pregn

1969
Determination of the drug sensitivity of Plasmodium falciparum.
    JAMA, 1971, Aug-02, Volume: 217, Issue:5

    Topics: Acute Disease; Amodiaquine; Antimalarials; Chloroquine; Drug Resistance, Microbial; Folic Acid Antag

1971
Curative and suppressive treatment of P. falciparum malaria with oral and parenteral Fansidar.
    The Southeast Asian journal of tropical medicine and public health, 1971, Volume: 2, Issue:1

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Chloroquine; Dapson

1971
The routine treatment of malaria.
    Tropical doctor, 1971, Volume: 1, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Chronic Disease

1971
[Fatal chloroquine poisoning].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1971, Aug-30, Volume: 26, Issue:35

    Topics: Acute Disease; Adolescent; Chloroquine; Female; Humans

1971
[Treatment of bronchial asthma with arechin].
    Gruzlica i choroby pluc; tuberculosis et pneumonologia, 1970, Volume: 38, Issue:11

    Topics: Acute Disease; Adult; Asthma; Chloroquine; Dexamethasone; Drug Synergism; Drug Tolerance; Female; Hu

1970
Acute malaria in newborn infants.
    British medical journal, 1970, Sep-19, Volume: 3, Issue:5724

    Topics: Acute Disease; Chloroquine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Malaria

1970
Acute chloroquine poisoning.
    The Practitioner, 1971, Volume: 207, Issue:238

    Topics: Acute Disease; Adult; Child, Preschool; Chloroquine; Female; Gastric Lavage; Heart Arrest; Humans; M

1971
[Clinical observations in patients with acute amebic dysentery].
    Medizinische Klinik, 1968, Jul-05, Volume: 63, Issue:27

    Topics: Acute Disease; Chloroquine; Colitis, Ulcerative; Diagnosis, Differential; Dysentery, Amebic; Emetine

1968
Management of sarcoidosis.
    Geriatrics, 1969, Volume: 24, Issue:6

    Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Aminobenzoates; Calcium; Child; Chloroquine; Chronic

1969