chloroquine has been researched along with AIDS Seroconversion in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ammonium chloride was also beneficial, suggesting that effects were mediated by alkalinizing the phagolysosome." | 1.30 | Chloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivation. ( Harrison, TS; Levitz, SM; Liu, X; Tabuni, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levitz, SM | 2 |
| Harrison, TS | 1 |
| Tabuni, A | 1 |
| Liu, X | 1 |
| Weber, SM | 1 |
2 other studies available for chloroquine and AIDS Seroconversion
| Article | Year |
|---|---|
Chloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivation.
Topics: Ammonium Chloride; Animals; Antifungal Agents; Apoproteins; Chloroquine; Cryptococcosis; Cryptococcu | 1997 |
Chloroquine antagonizes the proinflammatory cytokine response to opportunistic fungi by alkalizing the fungal phagolysosome.
Topics: Active Transport, Cell Nucleus; Ammonium Chloride; Anti-Bacterial Agents; Candida albicans; Cell Nuc | 2001 |