chlorophyll-a and Myositis

A pyropheophorbide-α-based building block (Ppa-PLGVRG-Van) can be used to construct self-aggregated superstructures in vivo for highly specific and sensitive diagnosis of bacterial infection by noninvasive photoacoustic tomography. This in vivo supramolecular chemistry approach opens a new avenue for efficient, rapid, and early-stage disease diagnosis with high sensitivity and specificity.

Topics: Animals; Bacterial Infections; Chlorophyll; Contrast Media; Disease Models, Animal; Escherichia coli; Gelatinases; Mice; Models, Biological; Molecular Structure; Myositis; Nanostructures; Phantoms, Imaging; Photoacoustic Techniques; Proteus vulgaris; Staphylococcus aureus; Staphylococcus epidermidis; Tomography; Vancomycin; Water