chloroform has been researched along with Experimental Hepatoma in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 14 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boobis, AR | 1 |
| Alison, MR; Anilkumar, TV; Edwards, RJ; Golding, M; Lalani, EN; Sarraf, CE | 1 |
| Baker, DC; Benjamin, SA; Constan, AA; Yang, RS | 1 |
| Butterworth, BE; Larson, JL; Wolf, DC | 2 |
| Anderson, MW; Anna, CH; Butterworth, BE; Devereux, TR; Lucier, GW; Maronpot, RR | 1 |
| Allen, BC; Clewell, HJ; Covington, TR | 1 |
| Dybing, E; Kroese, D; Roelfzema, H; Sanner, T; Tennant, RW | 1 |
| Golden, RJ; Holm, SE; Julkunen, PH; Reese, EA; Robinson, DE | 1 |
| Butterworth, BE; Constan, AA; Everitt, JI; Pluta, LJ; Recio, L; Sprankle, CS; Templin, MV; Wong, BA | 1 |
| Bhattacharya, S; Chatterjee, M | 1 |
| Calvisi, D; Carru, A; Daino, L; De Miglio, MR; Deiana, L; Feo, F; Muroni, MR; Pascale, RM; Pusceddu, S; Seddaiu, MA; Simile, MM | 1 |
| Cattley, RC; Corton, JC; Miller, RT; Swanson, C | 1 |
| Chan, SH; Morris, HP; Spitsberg, VL | 1 |
| Gemma, S; Testai, E; Vittozzi, L | 1 |
| Goodman, JI; Vorce, RL | 1 |
| Deml, E; Oesterle, D | 1 |
| Brown, JM; Bull, RJ; Jorgenson, TA; Meierhenry, EA; Robinson, M; Stober, JA | 1 |
| Klaunig, JE; Pereira, MA; Ruch, RJ | 1 |
| Herren-Freund, SL; Knutsen, GL; Pereira, MA | 1 |
| Bull, RJ; Jorgenson, TA; Meierhenry, EF; Robinson, M; Rushbrook, CJ | 1 |
3 review(s) available for chloroform and Experimental Hepatoma
| Article | Year |
|---|---|
Mode of action considerations in the quantitative assessment of tumour responses in the liver.
Topics: Animals; Carcinogenicity Tests; Cell Proliferation; Chloroform; Dose-Response Relationship, Drug; Humans; Kidney; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Models, Biological; Risk Assessment | 2010 |
Considerations concerning the murine hepatocarcinogenicity of selected chlorinated hydrocarbons.
Topics: Animals; Chloroform; Dichloroacetic Acid; Hydrocarbons, Chlorinated; Liver Neoplasms, Experimental; Male; Methylene Chloride; Mice; Polychlorinated Dibenzodioxins; Tetrachloroethylene; Trichloroethylene | 1995 |
Chloroform mode of action: implications for cancer risk assessment.
Topics: Administration, Inhalation; Administration, Oral; Animals; Carcinogens; Cell Death; Cell Division; Chloroform; Dose-Response Relationship, Drug; Female; Kidney Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Models, Biological; Mutagenicity Tests; Public Health; Rats; Risk Assessment; United States | 1997 |
18 other study(ies) available for chloroform and Experimental Hepatoma
| Article | Year |
|---|---|
The resistant hepatocyte model of carcinogenesis in the rat: the apparent independent development of oval cell proliferation and early nodules.
Topics: Acetates; Acetic Acid; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Bile Ducts; Blotting, Western; Carcinogens; Cell Division; Chloroform; Cytochrome P-450 Enzyme System; Disease Models, Animal; Drug Resistance; Electrophoresis; Hepatectomy; Immunohistochemistry; Intermediate Filaments; Liver; Liver Neoplasms, Experimental; Male; Methanol; Molecular Weight; Neoplasm Proteins; Rats; Rats, Inbred F344; Tissue Fixation | 1995 |
A unique pattern of hepatocyte proliferation in F344 rats following long-term exposures to low levels of a chemical mixture of groundwater contaminants.
Topics: Animals; Arsenic; Benzene; Cell Division; Chloroform; Chromium; Dose-Response Relationship, Drug; Fresh Water; Hazardous Substances; Lead; Liver; Liver Neoplasms, Experimental; Male; Mitosis; Phenol; Phenols; Rats; Rats, Inbred F344; Time Factors; Trichloroethylene; Water Pollutants, Chemical | 1995 |
Induced cytolethality and regenerative cell proliferation in the livers and kidneys of male B6C3F1 mice given chloroform by gavage.
Topics: Animals; Bromodeoxyuridine; Cell Death; Cell Division; Chloroform; Intubation, Gastrointestinal; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains | 1994 |
Induced cytotoxicity and cell proliferation in the hepatocarcinogenicity of chloroform in female B6C3F1 mice: comparison of administration by gavage in corn oil vs ad libitum in drinking water.
Topics: Administration, Oral; Animals; Bromodeoxyuridine; Cell Death; Cell Division; Chloroform; Female; Immunohistochemistry; Intubation, Gastrointestinal; Liver Neoplasms, Experimental; Mice; Mice, Inbred Strains; Water Supply | 1994 |
Investigation of the impact of pharmacokinetic variability and uncertainty on risks predicted with a pharmacokinetic model for chloroform.
Topics: Animals; Chloroform; Female; Humans; Liver Circulation; Liver Neoplasms, Experimental; Male; Mice; Models, Statistical; Risk Assessment | 1996 |
T25: a simplified carcinogenic potency index: description of the system and study of correlations between carcinogenic potency and species/site specificity and mutagenicity.
Topics: Abdominal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Butadienes; Carcinogenicity Tests; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Transitional Cell; Chloroform; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mesothelioma; Mice; Mutagenesis; Neoplasms, Experimental; Rats; Rats, Inbred F344; Species Specificity; Toluidines; Urinary Bladder Neoplasms | 1997 |
Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 mice.
Topics: Administration, Inhalation; Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Lac Operon; Liver; Liver Diseases; Liver Neoplasms, Experimental; Liver Regeneration; Mice; Mice, Transgenic; Organ Size; Precancerous Conditions; Transgenes | 1998 |
Trianthema portulacastrum restores the antioxidant defense enzyme levels and hepatic biotransformation patterns in experimental rat hepatocarcinogenesis.
Topics: Animals; Carcinogens; Chloroform; Cytochrome P-450 Enzyme System; Cytosol; Diethylnitrosamine; Ethanol; Glucuronosyltransferase; Glutathione; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Plant Extracts; Rats; Rats, Sprague-Dawley | 1998 |
Correlation of c-myc overexpression and amplification with progression of preneoplastic liver lesions to malignancy in the poorly susceptible Wistar rat strain.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Cell Transformation, Neoplastic; Chloroform; Diethylnitrosamine; Disease Progression; Disease Susceptibility; Gene Amplification; Gene Dosage; Gene Expression; Genes, myc; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Pancreatic Elastase; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Wistar; RNA, Messenger; Time Factors | 1999 |
Alteration of protein kinase C isoform-specific expression during rat hepatocarcinogenesis after exposure to the peroxisome proliferator WY-14,643.
Topics: Adenoma; Animals; Carcinogens; Chloroform; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; Protein Isoforms; Protein Kinase C; Pyrimidines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 1999 |
Isolation and comparative studies of mitochondrial F1-ATPase from Morris hepatoma and rat liver.
Topics: Adenosine Triphosphatases; Animals; Bicarbonates; Chemical Phenomena; Chemistry; Chloroform; Dinitrophenols; Electrophoresis, Polyacrylamide Gel; Liver Neoplasms, Experimental; Male; Mitochondria, Liver; Molecular Weight; Oxidative Phosphorylation; Rats; Temperature | 1979 |
Bioactivation of chloroform in hepatic microsomes from rodent strains susceptible or resistant to CHCl3 carcinogenicity.
Topics: Animals; Biotransformation; Carbon Radioisotopes; Carcinogens; Chloroform; DNA; Kidney Neoplasms; Lipid Metabolism; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidation-Reduction; Protein Binding; Proteins; Rats; Rats, Inbred Strains; Rodentia; Species Specificity | 1992 |
Hypomethylation of ras oncogenes in chemically induced and spontaneous B6C3F1 mouse liver tumors.
Topics: Animals; Carcinoma, Hepatocellular; Chloroform; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methylation; Mice; Phenobarbital; Restriction Mapping; Rodent Diseases | 1991 |
Dose-response of promotion by polychlorinated biphenyls and chloroform in rat liver foci bioassay.
Topics: Adenosine Triphosphatases; Animals; Chloroform; Diethylnitrosamine; Female; gamma-Glutamyltransferase; Liver Glycogen; Liver Neoplasms, Experimental; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains | 1987 |
Enhancement of the hepatotoxicity of chloroform in B6C3F1 mice by corn oil: implications for chloroform carcinogenesis.
Topics: Animals; Chloroform; Cocarcinogenesis; Corn Oil; Dietary Fats, Unsaturated; Female; Kidney Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mutagenicity Tests; Plant Oils; Rats; Water Supply | 1986 |
Carcinogenicity of chlorinated methane and ethane compounds administered in drinking water to mice.
Topics: Animals; Carcinogens; Chloroform; Disinfectants; Ethylene Dichlorides; Female; Hydrocarbons, Chlorinated; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Water Supply | 1986 |
Effect of subsequent treatment of chloroform or phenobarbital on the incidence of liver and lung tumors initiated by ethylnitrosourea in 15 day old mice.
Topics: Animals; Chloroform; Cocarcinogenesis; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Phenobarbital; Sex Factors | 1985 |
Carcinogenicity of chloroform in drinking water to male Osborne-Mendel rats and female B6C3F1 mice.
Topics: Animals; Chloroform; Dose-Response Relationship, Drug; Female; Kidney Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Oils; Rats | 1985 |