chloroform has been researched along with Acute Liver Injury, Drug-Induced in 151 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 100 (66.23) | 18.7374 |
1990's | 26 (17.22) | 18.2507 |
2000's | 13 (8.61) | 29.6817 |
2010's | 10 (6.62) | 24.3611 |
2020's | 2 (1.32) | 2.80 |
Authors | Studies |
---|---|
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Abdul Kadir, A; Abdullah, S; Azizah, R; Balan, T; Hizami Azmi, A; Omar, MH; Sahmat, A; Sulistyorini, L; Zainol, ASN; Zakaria, ZA | 1 |
Abdullah, MNH; Azizah, R; Azmi, AH; Balan, T; Nur Zainol, AS; Omar, MH; Sahmat, A; Sulistyorini, L; Zakaria, ZA | 1 |
Abshagen, K; Genz, B; Rotberg, T; Vollmar, B | 1 |
Chen, C; Li, X; Wang, L | 1 |
Armstrong, J; Gault, A; Vlad, IA | 1 |
Broska, J; Cowie, C; Gunja, N; Isbister, GK; Islam, S; Jayaweera, D; Poojara, L; Roberts, MS | 1 |
Chanda, S; Nair, R; Tanna, A | 1 |
Kim, H | 1 |
Abdel-Kader, MS; Al-Taweel, AM; Alqasoumi, SI | 1 |
Ameh, DA; Atawodi, SE; Ene, AC | 1 |
Chang, SJ; Chang, WH; Chen, JJ; Huang, S; Yang, M | 1 |
Krishnakishore, C; Manjusha, Y; Sandeep, Y; Sivakumar, V; Sridhar, N; Sriramnaveen, P | 1 |
Ariamuthu, S; Chellappan, DK; Kalusalingam, A; Mohan, S; Samuel, AJ | 1 |
Begay, CK; Gandolfi, AJ | 1 |
Anand, SS; Mehendale, HM; Mumtaz, MM; Murthy, SN; Vaidya, VS | 1 |
YAMASAKI, I | 1 |
KYLIN, B; REICHARD, H; SUEMEGI, I; YLLNER, S | 1 |
GRIFFITHS, HW | 2 |
BALLAN, P; CATANZANO, G; MAHON, R; MORETTI, GF; STAEFFEN, J; VANDENDRIESSCHE, M | 2 |
WEIR, DM | 1 |
FASSOLT, A | 1 |
SHERLOCK, S | 1 |
ROLLASON, WN | 1 |
BALESTRA, L; GIARDINA, B | 1 |
KRISTOFFERSEN, M | 1 |
HELLEKANT, G | 1 |
DUNDEE, JW; KIRWAN, MJ; NEILL, DW | 1 |
DAVIS, HS; LEONARD, D; WINGARD, D | 1 |
CARROLL, R; TAPP, E | 1 |
SLATER, TF | 1 |
Kim, SK; Kim, YC | 2 |
Omidi, A; Rakhshandeh, H; Vahdati-Mashhadian, N | 1 |
Abrol, S; Katare, OP; Trehan, A | 1 |
Chan, CC; Du, CL; Lin, CH; Wang, JD | 1 |
Ghosh, A; Sarkar, K; Sil, PC | 1 |
Choi, SH; Hong, YS; Kim, SJ; Lee, SW; Moon, JD; Moon, SW | 1 |
Anand, SS; Latendresse, JR; Mehendale, HM; Mumtaz, MM; Palkar, PS; Philip, BK | 1 |
Tylleskär-Jensen, J | 1 |
Hashizume, Y; Kawai, M; Mizuhara, M; Takahashi, Y; Yonemoto, H | 1 |
Doyle, RE; Lewis, AL; Moreland, AF; Woodard, JC | 1 |
Ekström, T; Högberg, J; Jernström, B | 1 |
Dent, JG; Leonard, TB | 1 |
Cianflone, DJ; Hewitt, WR; Plaa, GL; Villeneuve, DC | 1 |
Brown, EM; Hewitt, WR | 1 |
Anders, MW; Harris, RN | 1 |
Brown, EM; Hewitt, WR; Plaa, GL | 1 |
Lesca, P | 1 |
Anders, MW; Garry, VF; Shen, ES | 1 |
Reddrop, CJ; Riess, W; Slater, TF | 1 |
Côté, MG; Hewitt, WR; Miyajima, H; Plaa, GL | 2 |
Jones, RM; Kenna, JG | 1 |
Aiking, H; Feenstra, JF; Scholten, RJ; Valkenburg, HA; van Acker, MB | 1 |
Azri-Meehan, S; Brendel, K; Gandolfi, AJ; Mata, HP | 1 |
Butterworth, BE; Larson, JL; Méry, S; Morgan, KT; Wolf, DC | 1 |
Lin, CC; Lin, CH | 1 |
Deng, JF; Ger, J; Huang, YS; Lin, WL; Yao, C | 1 |
Butterworth, BE; Larson, JL; Wolf, DC | 1 |
Butterworth, BE; Jamison, KC; Morgan, KT; Templin, MV; Wolf, DC | 1 |
Kaneko, T; Nakano, M; Sato, A; Tsukada, H; Wang, PY | 1 |
Gandolfi, AJ; Lind, RC | 2 |
Fariss, MW; Lippman, HR; Mumaw, VR; Ray, SD | 1 |
Kontorshchikova, KN; Peretiagin, SP; Solopaeva, IM | 1 |
Spence, AA; Thorpe, CM | 1 |
Butterworth, BE; Horesovsky, GJ; Kegelmeyer, AE; Sprankle, CS | 1 |
Lilly, PD; Pegram, RA; Ross, TM | 1 |
Butterworth, BE; Constan, AA; Everitt, JI; Pluta, LJ; Recio, L; Sprankle, CS; Templin, MV; Wong, BA | 1 |
Hennig, GE; Manautou, JE; Silva, VM; Whiteley, HE | 1 |
Handa, SS; Karan, M; Vasisht, K | 1 |
Begay, CK; Gandolfi, AJ; Lind, RC | 1 |
Ford, JH; Gopinath, C | 1 |
Frimmer, M; Homann, J; Rufeger, U | 1 |
Sümegi, I | 1 |
Bullock, LP; Clemens, TL; Hill, RN; Johnson, WD; Sultatos, LG; Vesell, ES | 1 |
McBride, JG; Murray, FJ; Schwetz, BA; Staples, RE | 1 |
Barth, ML; Cornish, HH; Ling, B | 1 |
Krishna, G; Pohl, LR | 1 |
Dessì, A; Dore, M; Montaldo, C; Sanna, A; Vargiolu, S | 1 |
Frimmer, M; Homann, J; Petzinger, E | 1 |
Reynolds, ES | 1 |
Adam, SE; Madani, MO | 1 |
Smuckler, EA | 1 |
Plaa, GL | 1 |
Hanasono, GK; Plaa, GL; Witschi, H | 1 |
Maudet, M; Nicol, M; Savouré, N | 1 |
Hakim, A; Jain, AK; Jain, R | 1 |
Berndt, WO; Davis, ME | 1 |
Mehendale, HM; Rao, SB; Young, RA | 1 |
Borzelleca, JF; Condie, LW; Gennings, C; Granger, RH; O'Hara, TM; Sheppard, MA | 1 |
du Souich, P; Greselin, E; Kobusch, AB; Plaa, GL; Vézina, M | 1 |
Caillé, G; Côté, MG; Iijima, M; Plaa, GL; Vézina, M | 1 |
Lockard, VG; Mehendale, HM; Purushotham, KR | 1 |
Moritz, RP; Pankow, D | 1 |
Ebel, RE | 1 |
Brady, JF; Ishizaki, H; Lee, M; Li, D; Ning, SM; Xiao, F; Yang, CS | 1 |
Barakat, SE; Ford, EJ | 1 |
Belotti, L; Cassina, G; Marchesi, D; Mecca, G; Mosconi, G; Seghizzi, P | 1 |
Hewitt, LA; Plaa, GL; Valiquette, C | 1 |
Stacey, NH | 1 |
Perrissoud, D; Testa, B | 1 |
Inishi, S; Katoh, M; Nokata, M; Sugimoto, T | 1 |
Landon, EJ; Naukam, RJ; Rama Sastry, BV | 1 |
Hutchens, KS; Küng, M | 1 |
Monk, IB | 1 |
Geddes, IC | 1 |
Ford, EJ; Gopinath, C; Jones, RS; Thorpe, E | 1 |
Ford, EJ; Gopinath, C; Jones, RS | 1 |
Lavigne, JG; Marchand, C | 1 |
Reynolds, ES; Yee, AG | 1 |
Evreux, J; Motin, J; Paliard, P | 1 |
Glende, EA; Koch, RR; Recknagel, RO | 1 |
Brown, BR; Sagalyn, AM; Sipes, IG | 1 |
Khokhlov, AP; Maliugin, EF; Ostroverkhov, GE; Rykov, VI; Terent'eva, VB | 1 |
Ford, EJ; Gopinath, C | 1 |
Corssen, G | 1 |
Dykes, MH | 2 |
Mallory, TH; St Pierre, RL; Stone, WA | 1 |
Barth, ML; Cornish, HH; Ling, BP | 1 |
Farina, G; Gambini, G | 1 |
Plaa, GL; Traiger, GJ | 1 |
Brown, EA; Eichelbaum, FM; Gillette, JR; Maling, HM; Saul, W; Sipes, IG | 1 |
Burdino, E; Gabriel, L; Torrielli, MV; Ugazio, G | 1 |
Gehring, PJ; Leong, BK; Schwetz, BA | 1 |
Efrain Salvioli, J | 1 |
Scholler, KL | 3 |
Niessing, J; Schaude, G; Siess, M; Vogell, W | 1 |
Ramadan, MA; Ramadan, MI | 1 |
Hecker, D; Lohs, K; Meyer, M; Wildner, G | 1 |
Borzhievskiĭ, TsK; Karavanov, GG | 1 |
Borzhievskiĭ, TsK | 1 |
Zhdanov, GG | 1 |
Müller, E; Scholler, KL; von Plehwe, U | 1 |
Clauberg, G | 1 |
Bomski, H; Sobolewska, A; Strakowski, A | 1 |
Noritomi, S | 1 |
Aoki, T; Bombeck, CT; Nyhus, LM; Smuckler, EA | 1 |
Clot, C; Lande, M | 1 |
Schroeder, HG | 1 |
Brindle, GF; Galindo, A; Gilbert, RG; Maclean, LD | 1 |
Hansz, J; Owczarek, L | 1 |
5 review(s) available for chloroform and Acute Liver Injury, Drug-Induced
Article | Year |
---|---|
Metabolic activation and toxicology - some models of chemical protection against drug toxicity.
Topics: Acetaminophen; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 Enzyme System; Drug Antagonism; Drug-Related Side Effects and Adverse Reactions; Models, Biological; Polycyclic Compounds | 1981 |
The organ toxicity of inhaled anesthetics.
Topics: Anesthetics, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Disease Models, Animal; Enflurane; Ethers; Halothane; Humans; Isoflurane; Kidney; Liver; Methoxyflurane; Methyl Ethers; Sevoflurane; Trichloroethylene; Vinyl Compounds | 1995 |
Metabolism of volatile anaesthetics.
Topics: Adipose Tissue; Anesthetics; Animals; Carbon Isotopes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlorine; Chloroform; Cyclopropanes; Enzyme Induction; Ethers; Ethyl Ethers; Ethylenes; Halothane; Humans; Liver; Methoxyflurane; Radioisotopes; Trichloroethylene | 1972 |
Location of liver injury and extent of bilirubinaemia in experimental liver lesions.
Topics: Animals; Bilirubin; Carbon Tetrachloride Poisoning; Cattle; Cattle Diseases; Chemical and Drug Induced Liver Injury; Chloroform; Copper; Horse Diseases; Horses; Liver; Liver Diseases; Necrosis; Plant Poisoning; Sheep; Sheep Diseases; Sulfates; Thiocyanates | 1972 |
[Liver diseases induced by drugs].
Topics: Animals; Arsenicals; Chemical and Drug Induced Liver Injury; Chloroform; Chlorpromazine; Contraceptives, Oral; Drug Hypersensitivity; Humans; Isoniazid; Liver Diseases; Steroids; Tannins; Tetracycline | 1967 |
146 other study(ies) available for chloroform and Acute Liver Injury, Drug-Induced
Article | Year |
---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Liver protective effect of chloroform extract of
Topics: Acetaminophen; Animals; Antioxidants; Bauhinia; Chemical and Drug Induced Liver Injury; Chloroform; Flavonoids; Liver; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley | 2023 |
Polyphenolics and triterpenes presence in chloroform extract of Dicranopteris linearis leaves attenuated paracetamol-induced liver intoxication in rat.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Liver; Male; Oxidative Stress; Plant Extracts; Plant Leaves; Polyphenols; Rats; Rats, Sprague-Dawley; Tracheophyta; Triterpenes | 2021 |
No significant impact of Foxf1 siRNA treatment in acute and chronic CCl
Topics: Animals; Biological Products; Biological Therapy; Chemical and Drug Induced Liver Injury; Chloroform; Disease Models, Animal; Forkhead Transcription Factors; Liver; Mice; RNA, Small Interfering; Treatment Outcome | 2017 |
3-methyadenine attenuates chloroform-induced hepatotoxicity via autophagy activation.
Topics: Adenine; Animals; Autophagy; Chemical and Drug Induced Liver Injury; Chloroform; Cytokines; Disease Models, Animal; Glutathione; Inflammation Mediators; Liver; Male; Malondialdehyde; Mice; Oxidative Stress; Protective Agents | 2018 |
A painless burn: systemic toxicity after dermal exposure to chloroform.
Topics: Adult; Burns, Chemical; Burns, Inhalation; Chemical and Drug Induced Liver Injury; Chloroform; Humans; Male; Solvents | 2014 |
Chloroform ingestion causing severe gastrointestinal injury, hepatotoxicity and dermatitis confirmed with plasma chloroform concentrations.
Topics: Abdominal Pain; Acetylcysteine; Adult; Antidotes; Chemical and Drug Induced Liver Injury; Chloroform; Drug Eruptions; Drug Overdose; Female; Gastrointestinal Diseases; Half-Life; Humans; Liver Function Tests; Models, Biological; Respiratory Insufficiency | 2017 |
Assessment of anti-inflammatory and hepatoprotective potency of Polyalthia longifolia var. pendula leaf in Wistar albino rats.
Topics: Acetone; Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chloroform; Diclofenac; Dose-Response Relationship, Drug; Female; Glycogen; Hexanes; Liver; Liver Diseases; Male; Methanol; Plant Extracts; Plant Leaves; Polyalthia; Rats; Rats, Wistar; Toluene | 2009 |
A case of acute toxic hepatitis after suicidal chloroform and dichloromethane ingestion.
Topics: Chemical and Drug Induced Liver Injury; Chloroform; Humans; Male; Methylene Chloride; Solvents; Suicide, Attempted; Young Adult | 2008 |
Hepatoprotective constituents from Cleome droserifolia.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Carbohydrate Sequence; Chemical and Drug Induced Liver Injury; Chloroform; Cleome; Ethanol; Liver; Liver Function Tests; Magnetic Resonance Spectroscopy; Male; Methanol; Molecular Sequence Data; Plant Extracts; Protective Agents; Rats; Rats, Wistar; Solvents; Spectrophotometry, Ultraviolet | 2009 |
Hepatotoxic effects of chloroform extract of Artemisia macivera Linn in rats following intraperitoneal administration of different subchronic doses.
Topics: Animals; Antimalarials; Artemisia; Body Weight; Chemical and Drug Induced Liver Injury; Chloroform; Diet; Dose-Response Relationship, Drug; Liver; Male; Nigeria; Organ Size; Plant Extracts; Random Allocation; Rats; Risk Assessment; Time Factors | 2011 |
Nanoscale hepatoprotective herbal decoction attenuates hepatic stellate cell activity and chloroform-induced liver damage in mice.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chloroform; Drug Delivery Systems; Drugs, Chinese Herbal; Female; Hepatic Stellate Cells; Histocytochemistry; Liver; Liver Cirrhosis; Matrix Metalloproteinase 2; Mice; Mice, Inbred ICR; Nanoparticles; Nanotechnology; Organ Size; Particle Size; Protective Agents; Tissue Inhibitor of Metalloproteinase-1 | 2011 |
Chloroform poisoning--a case report.
Topics: Adult; Chemical and Drug Induced Liver Injury; Chloroform; Humans; Male; Renal Dialysis; Renal Insufficiency | 2011 |
Hibiscus vitifolius (Linn.) root extracts shows potent protective action against anti-tubercular drug induced hepatotoxicity.
Topics: Administration, Oral; Alkanes; Animals; Antioxidants; Antitubercular Agents; Biomarkers; Chemical and Drug Induced Liver Injury; Chloroform; Cytoprotection; Disease Models, Animal; Female; Hibiscus; Lethal Dose 50; Liver; Liver Function Tests; Male; Methanol; Mice; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Roots; Plants, Medicinal; Rats; Rats, Wistar; Solvents; Water | 2012 |
Late administration of COX-2 inhibitors minimize hepatic necrosis in chloroform induced liver injury.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cyclooxygenase Inhibitors; Cytoprotection; Disease Models, Animal; Hepatocytes; Indomethacin; Male; Necrosis; Nitrobenzenes; Rats; Rats, Sprague-Dawley; Sulfonamides | 2003 |
Tissue repair plays pivotal role in final outcome of liver injury following chloroform and allyl alcohol binary mixture.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Chromatography, Gas; DNA; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraperitoneal; Liver; Liver Regeneration; Longevity; Male; Propanols; Rats; Rats, Sprague-Dawley | 2003 |
[On the influence of a low-protein diet on the pathogenesis of jaundice due to chloroform poisoning].
Topics: Chemical and Drug Induced Liver Injury; Chloroform; Diet, Protein-Restricted; Hepatitis; Hepatitis A; Humans; Jaundice; Protein Deficiency | 1963 |
HEPATOTOXICITY OF INHALED TRICHLOROETHYLENE, TETRACHLOROETHYLENE AND CHLOROFORM. SINGLE EXPOSURE.
Topics: Carbon Dioxide; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Chloroform; Fatty Liver; Hepatitis; Hepatitis A; Hepatitis, Animal; Mice; Pathology; Phosphotransferases; Research; Tetrachloroethylene; Toxicology; Trichloroethylene | 1963 |
EFFECTS OF CHLOROFORM AND HALOTHANE ANESTHESIA ON LIVER FUNCTION IN MAN.
Topics: Alanine Transaminase; Anesthesia; Anesthesia, Inhalation; Aspartate Aminotransferases; Bilirubin; Blood; Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Hepatitis; Liver; Liver Function Tests; Pharmacology; Surgical Procedures, Operative; Toxicology | 1964 |
[SERUM ORNITHINE CARBAMOYL TRANSFERASE (S-OCT) AND CHLOROFORM ANESTHESIA IN OBSTETRICS. PRELIMINARY STUDY OF LIVER DAMAGE].
Topics: Adolescent; Alanine Transaminase; Anesthesia; Anesthesia, Obstetrical; Aspartate Aminotransferases; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Chloroform; Clinical Enzyme Tests; D-Alanine Transaminase; Hepatitis; Liver Diseases; Obstetrics; Ornithine; Ornithine Carbamoyltransferase; Toxicology; Transferases | 1963 |
[A SENSITIVE AND RELIABLE TEST OF HEPATIC CELLULAR DISTRESS: DETERMINATION OF THE SERUM ORNITHINE CARBAMOYL TRANSFERASE (S-OCT). ITS APPLICATION TO THE STUDY OF LIMINAL HEPATIC DISTRESS DURING CHLOROFORM ANESTHESIA IN OBSTETRICS].
Topics: Anesthesia; Anesthesia, Obstetrical; Chemical and Drug Induced Liver Injury; Chloroform; Clinical Enzyme Tests; Hepatitis; Obstetrics; Ornithine; Ornithine Carbamoyltransferase; Pregnancy; Toxicology; Transferases | 1963 |
IMMUNOLOGICAL REACTIONS AFTER TISSUE DAMAGE.
Topics: Amides; Chemical and Drug Induced Liver Injury; Chloroform; Complement Fixation Tests; Hepatitis; Nitrosamines; Paraffin; Rats; Research; Sulfhydryl Compounds; Tannins; Toxicology | 1964 |
EFFECTS OF CHLOROFORM AND HALOTHANE ANAESTHESIA ON LIVER FUNCTION.
Topics: Anesthesia; Anesthesiology; Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Hepatitis; Toxicology | 1964 |
[EXPERIENCES WITH HALOTHANE IN GYNECOLOGY AND OBSTETRICS].
Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Obstetrical; Angiotensins; Cesarean Section; Chemical and Drug Induced Liver Injury; Chloroform; Epinephrine; Ether; Female; Gynecology; Halothane; Hepatitis; Hypotension; Obstetrics; Pregnancy; Thiopental; Toxicology | 1964 |
HALOTHANE AND THE LIVER.
Topics: Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Hepatitis; Jaundice; Liver Diseases; Necrosis; Toxicology | 1964 |
CHLOROFORM, HALOTHANE, AND HEPATOTOXICITY.
Topics: Alanine Transaminase; Chemical and Drug Induced Liver Injury; Chloroform; Clinical Enzyme Tests; D-Alanine Transaminase; Halothane; Hepatitis; Liver Function Tests; Toxicology | 1964 |
[COMPARATIVE EXPERIMENTAL STUDY OF THE HISTOLOGICAL CHANGES IN THE LIVER AND KIDNEY IN ACUTE POISONING BY CHLOROFORM, FLUOTHANE AND METHOCYFLURANE].
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Hepatitis; Kidney; Kidney Diseases; Liver Diseases; Methoxyflurane; Necrosis; Rats; Research; Toxicology | 1964 |
[HEPATOTOXICITY OF THE LIVER].
Topics: Anesthetics; Barbiturates; Chemical and Drug Induced Liver Injury; Chloroform; Cyclopropanes; Ethanol; Ether; Ethyl Chloride; Ethylenes; Halothane; Hepatitis; Humans; Nitrous Oxide; Toxicology; Trichloroethylene; Vinyl Compounds | 1964 |
DISTRIBUTION OF CHLOROFORM-36CL IN MICE.
Topics: Brain; Chemical and Drug Induced Liver Injury; Chlorine; Chloroform; Fasting; Hepatitis; Kidney; Liver; Lung; Metabolism; Mice; Radioisotopes; Research; Toxicology | 1964 |
A COMPARISON OF THE EFFECTS OF CHLOROFORM AND HALOTHANE ON LIVER FUNCTION.
Topics: Alanine Transaminase; Anesthesia; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Chloroform; Cholinesterases; Clinical Enzyme Tests; Halothane; Hepatitis; Liver Function Tests; Nitrous Oxide; Preanesthetic Medication; Thiopental; Toxicology; Urine; Urobilinogen | 1965 |
EFFECTS OF HALOTHANE AND CHLOROFORM ON THE LIVER IN PROTEIN-DEFICIENT MICE.
Topics: Anesthesia; Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Hepatitis; Mice; Pathology; Protein Deficiency; Research; Toxicology | 1965 |
TETRACYCLINE ACCUMULATION IN TOXIC LIVER DAMAGE.
Topics: Amides; Calcium; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Edetic Acid; Fluorescence; Formates; Hepatitis; Hepatitis A; Metabolism; Necrosis; Pathology; Pharmacology; Promethazine; Rats; Research; Sulfhydryl Compounds; Tetracycline; Toxicology | 1965 |
A NOTE ON THE RELATIVE TOXIC ACTIVITIES OF TETRACHLOROMETHANE AND TRICHLORO-FLUORO-METHANE ON THE RAT.
Topics: Blood; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry, Physical; Chloroform; Fluorides; Glucuronidase; Hepatitis; Methane; NADP; Necrosis; Rats; Research; Solvents; Toxicology | 1965 |
Effects of betaine supplementation on hepatic metabolism of sulfur-containing amino acids in mice.
Topics: Amino Acids, Sulfur; Animals; Betaine; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; Glutathione; Kidney; Lipotropic Agents; Liver; Male; Methionine; Methionine Adenosyltransferase; Mice; Mice, Inbred ICR; S-Adenosylmethionine; Solvents; Taurine | 2005 |
An investigation on LD50 and subacute hepatic toxicity of Nigella sativa seed extracts in mice.
Topics: Alkaline Phosphatase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Lethal Dose 50; Methanol; Mice; Nigella; Plant Extracts; Seeds; Solvents; Water | 2005 |
Comparative study of different silymarin formulations: formulation, characterisation and in vitro/in vivo evaluation.
Topics: Administration, Oral; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biological Availability; Chemical and Drug Induced Liver Injury; Chloroform; Drug Carriers; Drug Evaluation, Preclinical; Emulsions; Injections, Intravenous; Liver; Male; Mice; Microspheres; Particle Size; Phospholipids; Rats; Rats, Wistar; Silymarin; Sleep; Solutions | 2005 |
Saved by a material safety data sheet.
Topics: Adult; Air Pollutants, Occupational; Chemical and Drug Induced Liver Injury; Chloroform; Environmental Monitoring; Female; Hepatic Encephalopathy; Humans; Occupational Exposure; Occupational Health; Workplace | 2005 |
Protective effect of a 43 kD protein from the leaves of the herb, Cajanus indicus L on chloroform induced hepatic-disorder.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Cajanus; Catalase; Chemical and Drug Induced Liver Injury; Chloroform; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; In Vitro Techniques; Lipid Peroxidation; Liver; Male; Mice; Plant Leaves; Plant Proteins; Plants, Medicinal; Superoxide Dismutase; Time Factors | 2006 |
Diagnostic radiopacity and hepatotoxicity following chloroform ingestion: a case report.
Topics: Adult; Chemical and Drug Induced Liver Injury; Chloroform; Drug Overdose; Female; Humans; Liver Diseases; Radiography; Solvents; Suicide, Attempted | 2006 |
Subchronic chloroform priming protects mice from a subsequently administered lethal dose of chloroform.
Topics: Alanine Transaminase; Animals; Area Under Curve; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Drug Tolerance; Glutathione; Glutathione Reductase; Hepatocytes; Intubation, Gastrointestinal; Kidney; Kidney Diseases; Liver Diseases; Mice; Survival Rate | 2006 |
[Chloroform--a cause of pregnancy toxemia?].
Topics: Adult; Chemical and Drug Induced Liver Injury; Chloroform; Eclampsia; Environmental Exposure; Environmental Health; Female; Humans; Pregnancy | 1967 |
[Studies of liver and bile duct functions. 3. 131-I-rose bengal test of experimental liver disorders in rabbits].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Iodine Radioisotopes; Liver Diseases; Liver Function Tests; Male; Rabbits; Rose Bengal | 1967 |
Mortality in Swiss mice exposed to chloroform.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Female; Mice; Pasteurella; Rodent Diseases | 1967 |
Inhibition of hepatic gamma-glutamyl-cysteine synthetase by chloroform.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Glutamate-Cysteine Ligase; Glutathione; Liver; Male; Peptide Synthases; Rats; Rats, Inbred Strains | 1982 |
Effects of H2 receptor antagonists on the hepatotoxicity of various chemicals.
Topics: 1-Propanol; Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Cimetidine; Drug Antagonism; Drug Synergism; Histamine H2 Antagonists; Imidazoles; Liver; Male; Propanols; Pyrimidinones; Ranitidine; Rats; Rats, Inbred F344 | 1984 |
Role of biotransformation in the alterations of chloroform hepatotoxicity produced by Kepone and mirex.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chlordecone; Chloroform; Drug Interactions; Glutathione; Insecticides; Male; Mice; Mirex; Mixed Function Oxygenases; Pesticide Residues | 1980 |
Dose-response relationships in ketone-induced potentiation of chloroform hepato- and nephrotoxicity.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Dose-Response Relationship, Drug; Drug Synergism; Ketones; Kidney Diseases; Male; Necrosis; Rats; Rats, Inbred F344 | 1984 |
Phosgene: a possible role in the potentiation of carbon tetrachloride hepatotoxicity by 2-propanol.
Topics: 1-Propanol; Animals; Carbon Dioxide; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Male; Microsomes, Liver; Phenobarbital; Phosgene; Rats | 1981 |
Relationship between the carbon skeleton length of ketonic solvents and potentiation of chloroform-induced hepatotoxicity in rats.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Drug Synergism; Ketones; Male; Organ Size; Ornithine Carbamoyltransferase; Rats; Rats, Inbred Strains; Solvents; Structure-Activity Relationship | 1983 |
Effect of hypoxia on carbon tetrachloride hepatotoxicity.
Topics: Alanine Transaminase; Animals; Binding Sites; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 Enzyme System; Hypoxia; Lipid Peroxides; Liver; Male; Microsomes, Liver; Oxygen Consumption; Rats | 1982 |
Two rapid methods for the simultaneous gas-liquid chromatographic determination of carbon tetrachloride and chloroform in biological material and expired air.
Topics: Air; Animals; Breath Tests; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Chromatography, Gas; Evaluation Studies as Topic; Microsomes, Liver; Rats | 1980 |
Acute alteration of chloroform-induced hepato- and nephrotoxicity by n-hexane, methyl n-butyl ketone, and 2,5-hexanedione.
Topics: Animals; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chloroform; Drug Synergism; Hexanes; Hexanones; Ketones; Kidney Cortex; Kidney Diseases; Male; Methyl n-Butyl Ketone; p-Aminohippuric Acid; Rats; Tetraethylammonium Compounds | 1980 |
Modification of haloalkane-induced hepatotoxicity by exogenous ketones and metabolic ketosis.
Topics: Acidosis; Alanine Transaminase; Animals; Butylene Glycols; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Diabetes Complications; Drug Synergism; Ketones; Ketosis; Liver Diseases; Rats | 1980 |
Swimming pool chlorination: a health hazard?
Topics: Alanine Transaminase; Aspartate Aminotransferases; beta 2-Microglobulin; Chemical and Drug Induced Liver Injury; Chlorine; Chloroform; gamma-Glutamyltransferase; Humans; Kidney Diseases; Liver; Liver Diseases; Pilot Projects; Risk Factors; Swimming Pools; Time Factors | 1994 |
The interactive toxicity of CHCl3 and BrCCl3 in precision-cut rat liver slices.
Topics: Animals; Biomarkers; Bromotrichloromethane; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 Enzyme System; Drug Interactions; Electrolytes; Glucosephosphate Dehydrogenase; Glutathione; In Vitro Techniques; Isocitrate Dehydrogenase; Lipid Peroxidation; Liver; Male; Potassium; Rats; Rats, Sprague-Dawley | 1994 |
The toxicity of 1-week exposures to inhaled chloroform in female B6C3F1 mice and male F-344 rats.
Topics: Administration, Inhalation; Animals; Bromodeoxyuridine; Cell Division; Cell Nucleus; Chemical and Drug Induced Liver Injury; Chloroform; DNA; Epithelium; Female; Immunohistochemistry; Kidney Diseases; Male; Mice; Mice, Inbred Strains; Nasal Bone; Olfactory Mucosa; Organ Size; Rats; Rats, Inbred F344; Weight Gain | 1994 |
Pharmacological and pathological studies on Taiwan folk medicine (IX): The hepatoprotective effect of the methanolic extract from echinops grijisii.
Topics: 1-Butanol; Acetates; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biopsy; Butanols; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Disease Models, Animal; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Inflammation; Liver Diseases; Methanol; Rats; Rats, Wistar | 1993 |
[Chloroform-induced hepatic injury: a case report].
Topics: Adult; Chemical and Drug Induced Liver Injury; Chloroform; Female; Humans; Occupational Exposure | 1993 |
Acute hepatotoxic and nephrotoxic effects of chloroform in male F-344 rats and female B6C3F1 mice.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chloroform; Dose-Response Relationship, Drug; Female; Kidney; Kidney Diseases; Liver; Male; Mice; Mice, Inbred Strains; Organ Size; Rats; Rats, Inbred F344; Species Specificity | 1993 |
Comparison of chloroform-induced toxicity in the kidneys, liver, and nasal passages of male Osborne-Mendel and F-344 rats.
Topics: Animals; Cell Division; Chemical and Drug Induced Liver Injury; Chloroform; Kidney; Kidney Diseases; Liver; Liver Diseases; Liver Regeneration; Male; Paranasal Sinuses; Rats; Rats, Inbred F344; Regeneration; Sensitivity and Specificity | 1996 |
Dose- and route-dependent alterations in metabolism and toxicity of chemical compounds in ethanol-treated rats: difference between highly (chloroform) and poorly (carbon tetrachloride) metabolized hepatotoxic compounds.
Topics: Administration, Inhalation; Administration, Oral; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Enzyme Induction; Ethanol; Glutathione; Injections, Intraperitoneal; Liver; Male; Metabolic Clearance Rate; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Wistar | 1997 |
Late dimethyl sulfoxide administration provides a protective action against chemically induced injury in both the liver and the kidney.
Topics: Administration, Inhalation; Administration, Oral; Alanine Transaminase; Allyl Compounds; Animals; Biomarkers; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Chloroform; Dimethyl Sulfoxide; Drug Administration Schedule; Glutathione; Guinea Pigs; Halothane; Kidney; Kidney Tubular Necrosis, Acute; Liver; Male; Necrosis; Rats; Rats, Sprague-Dawley; Sulfides | 1997 |
Cholesteryl hemisuccinate treatment protects rodents from the toxic effects of acetaminophen, adriamycin, carbon tetrachloride, chloroform and galactosamine.
Topics: Acetaminophen; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Cholesterol Esters; Doxorubicin; Galactosamine; Heart Diseases; Liver Diseases; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley | 1997 |
[Effect of ozone on the liver state in experimental chronic hepatitis].
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Lipid Peroxidation; Liver; Liver Regeneration; Oxidants, Photochemical; Ozone; Rats; Superoxide Dismutase | 1996 |
Clinical evidence for delayed chloroform poisoning.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Chemical and Drug Induced Liver Injury; Chloroform; Controlled Clinical Trials as Topic; History, 19th Century; History, 20th Century; Humans; Liver Diseases; Medical Records; Time Factors | 1997 |
Differential display identified changes in mRNA levels in regenerating livers from chloroform-treated mice.
Topics: Animals; Base Sequence; Blotting, Northern; Carcinogens; Chemical and Drug Induced Liver Injury; Chloroform; DNA, Complementary; Female; Gene Expression; Liver; Liver Diseases; Liver Regeneration; Mice; Molecular Sequence Data; Rats; RNA, Messenger; Sequence Homology, Nucleic Acid | 1997 |
Trihalomethane comparative toxicity: acute renal and hepatic toxicity of chloroform and bromodichloromethane following aqueous gavage.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chloroform; Hydrocarbons, Halogenated; Kidney Diseases; Male; Organ Size; Rats; Rats, Inbred F344; Solvents; Trihalomethanes | 1997 |
Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 mice.
Topics: Administration, Inhalation; Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Dimethylnitrosamine; Dose-Response Relationship, Drug; Female; Lac Operon; Liver; Liver Diseases; Liver Neoplasms, Experimental; Liver Regeneration; Mice; Mice, Transgenic; Organ Size; Precancerous Conditions; Transgenes | 1998 |
Repeated dosing with the peroxisome proliferator clofibrate decreases the toxicity of model hepatotoxic agents in male mice.
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Blood Urea Nitrogen; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Clofibrate; Injections, Intraperitoneal; Kidney; L-Iditol 2-Dehydrogenase; Liver; Male; Mice; Mice, Inbred C57BL; Microbodies; Sulfhydryl Compounds | 1998 |
Effects of singly administered betaine on hepatotoxicity of chloroform in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Betaine; Chemical and Drug Induced Liver Injury; Chloroform; Enzymes; Gastrointestinal Agents; Glutathione; Male; Mice; Mice, Inbred ICR; Organ Size; Succinate Dehydrogenase | 1998 |
Antihepatotoxic activity of Swertia chirata on carbon tetrachloride induced hepatotoxicity in rats.
Topics: Animals; Butanols; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Female; Hypnotics and Sedatives; India; Liver; Liver Function Tests; Male; Methanol; Mice; Mice, Inbred Strains; Pentobarbital; Plant Extracts; Plants, Medicinal; Rats; Sleep; Solvents | 1999 |
Hepatoprotection by dimethyl sulfoxide. II. Characterization of optimal dose and the latest time of administration for effective protection against chloroform and bromobenzene induced injury.
Topics: Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Chloroform; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Free Radical Scavengers; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Hepatoprotection by dimethyl sulfoxide. III. Role of inhibition of the bioactivation and covalent bonding of chloroform.
Topics: Alanine Transaminase; Allyl Compounds; Animals; Binding Sites; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 CYP2E1 Inhibitors; Dimethyl Sulfoxide; Enzyme Inhibitors; Free Radical Scavengers; Liver; Male; Rats; Rats, Sprague-Dawley; Sulfides; Time Factors; Triazoles | 2000 |
The role of microsomal hydroxylases in the modification of chloroform hepatotoxicity in rats.
Topics: Animals; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Chloroform; Chlorpromazine; DDT; Ditiocarb; Drug Interactions; Enzyme Induction; Female; Hexobarbital; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Phenylbutazone; Proadifen; Rats; Sleep | 1975 |
[Inhibition by diethyldithiocarbamate (DEDTC) of acute hepatotoxic effects induced by polyhalogenated hydrocarbons (PHHC)].
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Ditiocarb; Glutathione; Halothane; Hydrocarbons, Halogenated; Liver Diseases; Male; Microcirculation; Perfusion; Phenobarbital; Rats; Thiocarbamates; Trichloroethylene | 1976 |
Fibrinoid necrosis of liver parenchymal cells.
Topics: Adolescent; Adult; Aged; Animals; Autopsy; Chemical and Drug Induced Liver Injury; Child; Chloroform; Female; Hepatitis A; Humans; Liver Diseases; Magnetics; Male; Mice; Middle Aged; Necrosis; Polyarteritis Nodosa; Thrombophlebitis; Time Factors | 1975 |
Chloroform toxicity in the mouse: role of genetic factors and steroids.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Female; Genotype; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Regeneration; Species Specificity; Steroids; Testosterone | 1979 |
Toxicity of inhaled chloroform in pregnant mice and their offspring.
Topics: Abnormalities, Drug-Induced; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Embryo, Mammalian; Female; Fetal Resorption; Fetus; Gestational Age; Liver; Mice; Organ Size; Pregnancy; Teratogens | 1979 |
Influence of aliphatic alcohols on the hepatic response to halogenated olefins.
Topics: Alcohols; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Drug Synergism; Environmental Exposure; Ethanol; Hydrocarbons, Chlorinated; Liver; Phenobarbital; Rats; Trichloroethylene | 1977 |
Deuterium isotope effect in bioactivation and hepatotoxicity of chloroform.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cysteine; Cytochrome P-450 Enzyme System; Deuterium; Male; Microsomes, Liver; Phenobarbital; Rats; Thiazoles | 1978 |
[Protective effect of cadmium acetate in trichlorobromomethane poisoning].
Topics: Acetates; Animals; Bromotrichloromethane; Cadmium; Chemical and Drug Induced Liver Injury; Chloroform; Female; Liver; Male; Rats | 1978 |
[Phalloidin antagonists 4th communication: Thioctic acid, SH-compounds, rifampicin, choleretics, dexamethasone, estradiol, unspecific inhibitors, and ineffective compounds (author's transl)].
Topics: Animals; Chelating Agents; Chemical and Drug Induced Liver Injury; Chloroform; Cholagogues and Choleretics; Coenzyme A; Concanavalin A; Cysteamine; Cysteine; Dexamethasone; Dimercaprol; Estradiol; Female; Male; Oligopeptides; Phalloidine; Rats; Rifampin; Sulfhydryl Compounds; Thioctic Acid | 1975 |
Liver endoplasmic reticulum: target site of halocarbon metabolites.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Endoplasmic Reticulum; Enzyme Activation; Free Radicals; Hydrocarbons, Halogenated; Lipid Metabolism; Liver; Peroxides; Rats; Subcellular Fractions; Vinyl Chloride | 1977 |
Ligation of the bile duct and acute chloroform toxicity in the donkey.
Topics: Ammonia; Animals; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Injury; Chloroform; Cholestasis; Kidney Tubules; Ligation; Liver; Liver Diseases; Necrosis; Perissodactyla; Photosensitivity Disorders; Skin | 1976 |
Structural and functional changes in acute liver injury.
Topics: Animals; Calcium; Carbon Tetrachloride Poisoning; Cell Membrane; Chemical and Drug Induced Liver Injury; Chloroform; Dogs; Endoplasmic Reticulum; Lipid Metabolism; Liver; Liver Diseases; Mitochondria, Liver; Protein Biosynthesis; Rats; Ribosomes | 1976 |
Quantitative aspects in the assessment of liver injury.
Topics: 1-Propanol; Alanine Transaminase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Ethanol; Humans; Hydrocarbons, Halogenated; Lethal Dose 50; Lipid Metabolism; Liver; Liver Diseases; Mice; Microsomes, Liver; Pentobarbital; Rats; Sleep; Sulfobromophthalein; Tetrachloroethylene; Trichloroethanes; Trichloroethylene; Triglycerides | 1976 |
Potentiation of the hepatotoxic responses to chemicals in alloxan-diabetic rats.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Animals; Bilirubin; Blood Glucose; Chemical and Drug Induced Liver Injury; Chloroform; Diabetes Mellitus, Experimental; Ethane; Galactosamine; Hydrocarbons, Chlorinated; Insulin; Isocitrate Dehydrogenase; Liver; Male; Rats; Trichloroethylene; Triglycerides | 1975 |
[Toxicity of chloroform and vitamin A status in the rat].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chloroform; L-Lactate Dehydrogenase; Liver; Liver Diseases; Male; Nutritional Status; Ornithine Decarboxylase; Rats; Rats, Wistar; Vitamin A; Vitamin A Deficiency | 1992 |
Chloroform ingestion causing toxic hepatitis.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Chloroform; Female; Humans | 1992 |
Sex differences in monochloroacetate pretreatment effects on chloroform toxicity in rats.
Topics: Acetates; Animals; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chloroform; Dichloroacetic Acid; Female; Kidney Diseases; Kidney Function Tests; Liver Function Tests; Male; Potassium; Rats; Rats, Inbred Strains; Sex Characteristics; Sodium; Trichloroacetic Acid | 1992 |
Perturbations in polyamines and related enzymes following chlordecone-potentiated bromotrichloromethane hepatotoxicity.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Alanine Transaminase; Amino Acids, Diamino; Animals; Aspartate Aminotransferases; Bromotrichloromethane; Chemical and Drug Induced Liver Injury; Chlordecone; Chloroform; Insecticides; Liver; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred Strains | 1990 |
Interactions of water contaminants. I. Plasma enzyme activity and response surface methodology following gavage administration of CCl4 and CHCl3 or TCE singly and in combination in the rat.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Enzymes; L-Iditol 2-Dehydrogenase; Male; Rats; Rats, Inbred Strains; Trichloroethylene; Water Pollutants | 1990 |
Potentiation of chloroform-induced hepatotoxicity by methyl isobutyl ketone and two metabolites.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cholestasis; Densitometry; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Ketones; Male; Methyl n-Butyl Ketone; Microsomes, Liver; Mixed Function Oxygenases; Pentanols; Proteins; Rats; Rats, Inbred Strains | 1990 |
Chloroform interaction with chlordecone and mirex: correlation between biochemical and histological indices of toxicity and quantitative tissue levels.
Topics: Adipose Tissue; Animals; Chemical and Drug Induced Liver Injury; Chlordecone; Chloroform; Chromatography, Gas; Drug Interactions; Insecticides; Kidney; Kidney Diseases; Liver; Male; Mirex; Rats; Rats, Inbred Strains | 1987 |
The time course of liver injury and [3H]thymidine incorporation in chlordecone-potentiated CHCl3 hepatotoxicity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Nucleus; Chemical and Drug Induced Liver Injury; Chlordecone; Chloroform; DNA; Drug Synergism; Insecticides; Mice; Mirex; Phenobarbital; Time Factors | 1989 |
[Effect of carbon tetrachloride and chloroform on hematologic parameters in rats].
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Erythrocyte Count; Hematocrit; Hemoglobinometry; Male; Rats; Reticulocytes | 1989 |
Pyrazole treatment of rats potentiates CCL4-but not CHCL3-hepatotoxicity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Induction; Pyrazoles; Rats; Rats, Inbred Strains | 1989 |
Induction of cytochromes P450IIE1 and P450IIB1 by secondary ketones and the role of P450IIE1 in chloroform metabolism.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Chromatography, Gas; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Induction; Isoenzymes; Ketones; Male; Microsomes, Liver; Rats; Rats, Inbred Strains | 1989 |
Further studies on the diagnostic value of gamma-glutamyl transpeptidase and 5'-nucleotidase in cattle, sheep and horses.
Topics: 5'-Nucleotidase; Animals; Cattle; Cattle Diseases; Chemical and Drug Induced Liver Injury; Chloroform; gamma-Glutamyltransferase; Horse Diseases; Horses; Kidney Diseases; Liver Diseases; Male; Nucleotidases; Sheep; Sheep Diseases; Tissue Distribution | 1988 |
[Acute hepatonephritis in a subject occupationally exposed to chloroform].
Topics: Acute Disease; Biopsy; Chemical and Drug Induced Liver Injury; Chloroform; Humans; Male; Middle Aged; Nephritis; Occupational Diseases | 1988 |
The role of biotransformation-detoxication in acetone-, 2-butanone-, and 2-hexanone-potentiated chloroform-induced hepatotoxicity.
Topics: Acetone; Animals; Biotransformation; Butanones; Chemical and Drug Induced Liver Injury; Chloroform; Hexanones; Inactivation, Metabolic; Ketones; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Proteins; Rats; Rats, Inbred Strains | 1987 |
Assessment of the toxicity of chemical mixtures with isolated rat hepatocytes: cadmium and chloroform.
Topics: Animals; Aspartate Aminotransferases; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Potassium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
Inhibiting or potentiating effects of flavonoids on carbon tetrachloride-induced toxicity in isolated rat hepatocytes.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 Enzyme System; Drug Interactions; Flavonoids; Rats; Structure-Activity Relationship | 1986 |
[Protective effect of malotilate (diisopropyl 1,3-dithiol-2-ylidenemalonate) on chemical-induced hepatotoxicity].
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Liver; Liver Function Tests; Malonates; Mice; Mice, Inbred ICR; Rats | 1986 |
Effects of calcium channel blocking agents on calcium and centrilobular necrosis in the liver of rats treated with hepatotoxic agents.
Topics: Acetaminophen; Animals; Calcium; Calcium Channel Blockers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Dimethylnitrosamine; Liver; Male; Microsomes, Liver; Necrosis; Rats; Rats, Inbred Strains; Thioacetamide | 1986 |
"Experimentation" with chloroform.
Topics: Adult; Chemical and Drug Induced Liver Injury; Chloroform; Coma; Humans; Hypoxia; Liver Diseases; Male; Substance-Related Disorders; Tachycardia | 1985 |
Fluorocarbon propellants in aerosols.
Topics: Abortion, Spontaneous; Aerosol Propellants; Aerosols; Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Chloroform; Female; Halothane; Humans; Hydrocarbons, Halogenated; Occupational Diseases; Pregnancy | 1973 |
The effect of chloroform on the liver and the activity of serum enzymes in the horse.
Topics: Adenosine Triphosphatases; Animals; Aspartate Aminotransferases; Biopsy; Chemical and Drug Induced Liver Injury; Chloroform; Esterases; Glutamate Dehydrogenase; Histocytochemistry; Horses; Liver; Necrosis; Ornithine Carbamoyltransferase; Oxidoreductases; Sorbitol | 1969 |
The effects of chloroform or halothane on horse liver in the early stage of ragwort poisoning.
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Arginase; Bilirubin; Biopsy; Chemical and Drug Induced Liver Injury; Chloroform; Collagen; Eosinophils; Glutamate Dehydrogenase; Halothane; Hemorrhage; Histocytochemistry; Horses; Kupffer Cells; Leukocytes; Liver; Liver Glycogen; Necrosis; Plant Poisoning | 1972 |
The role of metabolism in chloroform hepatotoxicity.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chloroform; Liver; Male; Rats; Rats, Inbred Strains | 1974 |
Liver parenchymal cell injury. V. Relationships between patterns of chloromethane-C 14 incorporation into constituents of liver in vivo and cellular injury.
Topics: Animals; Autoradiography; Bicarbonates; Carbon; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Chromatography, Thin Layer; Endoplasmic Reticulum; Formaldehyde; Glucose-6-Phosphatase; Histocytochemistry; Lipid Metabolism; Liver; Male; Methyl Chloride; Microsomes; Mitochondria; Rats; RNA | 1967 |
[Severe toxic hepatitis].
Topics: Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Cortisone; Exchange Transfusion, Whole Blood; Humans; Hydrocarbons; Hydrocarbons, Halogenated; Hyperbaric Oxygenation; Jaundice; Methyltestosterone; Mushroom Poisoning; Phenothiazines; Phosphorus; Plant Poisoning | 1969 |
Hepatotoxicity of bromotrichloromethane--bond dissociation energy and lipoperoxidation.
Topics: Animals; Bromine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chloroform; Free Radicals; Hydrocarbons, Brominated; Hydrocarbons, Chlorinated; In Vitro Techniques; Kinetics; Lipid Metabolism; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Peroxides; Rats; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
Mechanisms of acute hepatic toxicity: chloroform, halothane, and glutathione.
Topics: Acute Disease; Anesthesia, Inhalation; Aniline Compounds; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chloroform; Chromatography, Gas; Cytochrome Reductases; Enzyme Induction; Glutathione; Halothane; Hexobarbital; Liver; Male; Maleates; Microsomes, Liver; Phenobarbital; Rats | 1974 |
[Hepatoprotective effect of glutamine].
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Dogs; Drug Evaluation; Drug Evaluation, Preclinical; Glutamine; Glycine; Histidine Ammonia-Lyase; Humans; Liver; Nucleic Acids; Peritonitis; Proteins; Urea; Urokinase-Type Plasminogen Activator | 1974 |
Anaesthesia and the liver--lessons from history?
Topics: Anesthesia, Inhalation; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Chloroform; Halothane; History, 19th Century; History, 20th Century; Humans; United Kingdom; United States | 1972 |
Cytotoxic effects of halogenated anaesthetics on cultured human liver and embryonic kidney cells.
Topics: Cell Membrane; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chloroform; Cytoplasm; Embryo, Mammalian; Halothane; Humans; Kidney; Liver; Methoxyflurane; Mitosis | 1973 |
Anaesthesia and the liver: history and epidemiology.
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Chloroform; Halothane; Humans; Liver; Liver Function Tests; Prognosis; Retrospective Studies; United States | 1973 |
Potential hepatotoxic effects of methylmethacrylate monomer.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Methylmethacrylates; Mice | 1973 |
Phenobarbital and organic solvent toxicity.
Topics: Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Drug Synergism; Environmental Exposure; Ethane; Hydrocarbons, Chlorinated; Hydrocarbons, Halogenated; Injections, Intraperitoneal; Liver; Male; Methane; Methyl Chloride; Phenobarbital; Rats; Solvents; Tetrachloroethylene; Trichloroethylene | 1973 |
[Hepatic function in workers exposed to inhalation of chloroform vapors].
Topics: Adult; Chemical and Drug Induced Liver Injury; Chloroform; Drug Industry; Environmental Exposure; Hepatomegaly; Humans; Liver; Liver Function Tests; Occupational Diseases | 1973 |
Chlorinated hydrocarbon toxicity. Potentiation by isopropyl alcohol and acetone.
Topics: 1-Propanol; Acetone; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Drug Synergism; Ethane; Hydrocarbons, Chlorinated; Injections, Intraperitoneal; Liver; Male; Mice; Trichloroethylene | 1974 |
Nature of the protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with dibenamine (N-(2-chloroethyl)dibenzylamine).
Topics: 1-Propanol; Animals; Carbon Radioisotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Dibenzylchlorethamine; Drug Synergism; Kidney; Lipid Metabolism; Liver; Male; Microsomes, Liver; Muscles; Phospholipids; Proteins; Rats; Time Factors | 1974 |
Effect of drug pretreatment on CBrCl3-induced liver injury.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromine; Chemical and Drug Induced Liver Injury; Chloroform; Drug Interactions; Fatty Liver; Hydrocarbons, Halogenated; Lipid Metabolism; Male; Microsomes, Liver; Necrosis; Peroxides; Phenobarbital; Phenylenediamines; Proadifen; Rats; Spectrophotometry, Ultraviolet; Time Factors; Triglycerides | 1974 |
Embryo- and fetotoxicity of inhaled chloroform in rats.
Topics: Abnormalities, Drug-Induced; Alanine Transaminase; Animals; Atmosphere; Body Weight; Chemical and Drug Induced Liver Injury; Chloroform; Embryo Implantation; Embryo, Mammalian; Embryonic and Fetal Development; Female; Fertility; Fetus; Liver; Organ Size; Pregnancy; Rats; Time Factors | 1974 |
Anesthesia and the liver. The early years: 1846-1912.
Topics: Anesthesia, General; Animals; Cats; Chemical and Drug Induced Liver Injury; Chloroform; Dogs; History, 19th Century; History, 20th Century; Humans; Rabbits | 1970 |
Electron-microscopic and autoradiographic studies on the effect of halothane and chloroform on liver cells.
Topics: Anesthesia, Inhalation; Animals; Autoradiography; Blood Coagulation Factors; Blood Volume; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Fatty Liver; Female; Fibrinogen; Halothane; Hepatitis A; Humans; Leucine; Liver; Liver Circulation; Microscopy, Electron; Microsomes; Oxygen; Protein Biosynthesis; Prothrombin; Rats; Ribosomes; RNA; Time Factors | 1968 |
[Histological, histochemical and electron microscopical findings in foreign substance induced liver hypertrophy in white mice].
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Endoplasmic Reticulum; Halothane; Hypertrophy; Liver Diseases; Liver Glycogen; Male; Mice; Microscopy, Electron; Mitochondria, Liver; Phenobarbital; Thiopental | 1967 |
Histochemical studies on the effect of some anaesthetics on rat liver.
Topics: Acid Phosphatase; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Endoplasmic Reticulum; Ethers; Halothane; Histocytochemistry; Liver; Rats; RNA; Trichloroethylene | 1969 |
[Enzyme histochemical studies on liver damage caused by halothane as compared to diethyl ether and chloroform].
Topics: Anesthesia, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Citric Acid Cycle; Ethyl Ethers; Halothane; Histocytochemistry; Hydrolases; Liver; Liver Glycogen; Male; Oxidoreductases; Rats; Rats, Inbred Strains | 1971 |
Anaesthesia and the liver.
Topics: Anesthesia; Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Dogs; Halothane; Humans; Liver; Liver Function Tests; Methoxyflurane; Starvation | 1972 |
[A comparative evaluation of the effects of different kinds of anesthesia on the liver as judged by sorbitol dehydrogenase activity].
Topics: Adult; Alcohol Oxidoreductases; Anesthesia, General; Chemical and Drug Induced Liver Injury; Chloroform; Clinical Enzyme Tests; Cyclopropanes; Ethyl Ethers; Female; Halothane; Humans; Liver Diseases; Male; Postoperative Complications; Trichloroethylene | 1972 |
[Evaluation of anesthetics according to their hepatotoxicity and ornithine carbamoyl-transferase activity].
Topics: Adult; Anesthesia, Inhalation; Anesthetics; Chemical and Drug Induced Liver Injury; Chloroform; Cyclopropanes; Ethyl Ethers; Female; Halothane; Humans; Liver; Male; Nitrous Oxide; Ornithine Carbamoyltransferase; Trichloroethylene | 1971 |
[Effect of anesthesia on the liver (histochemical study)].
Topics: Anesthetics; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Cyclopropanes; DNA; Ethyl Ethers; Halothane; Histocytochemistry; Liver; Liver Glycogen; Methods; Nitrous Oxide; Polysaccharides; Procaine; Proteins; Rats; RNA; Time Factors | 1969 |
[Increase of suppression of hepatotoxicity of chloroform].
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Liver; Male; Microsomes, Liver; Rats | 1970 |
Modification of the effects of chloroform on the rat liver.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Disulfiram; Enzyme Induction; Microsomes, Liver; Necrosis; Phenobarbital; Preanesthetic Medication; Rats; Thiopental; Transaminases | 1970 |
[Stimulation and depression of toxicity of chloroform for the liver by drugs].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chloroform; Depression, Chemical; Disulfiram; Drug Synergism; Female; Liver; Liver Diseases; Necrosis; Phenobarbital; Rats; Stimulation, Chemical | 1970 |
[Studies of the effect of an inhalation anesthesia and surgery on the liver function with special reference to halothane. 1].
Topics: Alanine Transaminase; Anesthesia, Inhalation; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Chloroform; Cyclopropanes; Ethyl Ethers; Fatty Liver; Halothane; L-Lactate Dehydrogenase; Liver; Methoxyflurane; Necrosis; Rats; Stimulation, Chemical; Trichloroethylene | 1970 |
[Toxic damage of the liver by chloroform in chemical industry workers].
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Chloroform; Environmental Exposure; Hepatitis A; Hepatomegaly; Humans; Occupational Diseases | 1967 |
Studies on the elimination of catecholamine in the dog's liver in vivo after the administration of adrenaline and noradrenaline.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Carbon Tetrachloride Poisoning; Catecholamines; Chemical and Drug Induced Liver Injury; Chloroform; Cholestasis; Dogs; Epinephrine; Female; Femoral Artery; Hepatic Veins; Liver; Male; Norepinephrine; Portal Vein | 1968 |
Effects of halothane, ether, and chloroform on the isolated, perfused, bovine liver. A comparative study.
Topics: Animals; Aspartate Aminotransferases; Cattle; Chemical and Drug Induced Liver Injury; Chloroform; Ethyl Ethers; Gluconeogenesis; Glycogen; Halothane; In Vitro Techniques; Lactates; Liver; Oxygen Consumption; Perfusion | 1969 |
[Halothane and liver toxicity].
Topics: Anesthesia, Inhalation; Chemical and Drug Induced Liver Injury; Chloroform; Fever; Halothane; Hepatitis A; Humans; Necrosis; Postoperative Complications; Transaminases | 1969 |
Acute and delayed chloroform poisoning. A case report.
Topics: Adult; Bicarbonates; Chemical and Drug Induced Liver Injury; Chloroform; Gastric Lavage; Glucose; Humans; Hypoxia; Male; Oxygen Inhalation Therapy; Resuscitation; Suicide | 1965 |
Hepatic circulation and hepatic function during anaesthesia and surgery. 3. Chloroform-induced liver injury.
Topics: Anesthesia; Animals; Chemical and Drug Induced Liver Injury; Chloroform; Dogs; In Vitro Techniques; Liver; Liver Circulation; Liver Function Tests; Surgical Procedures, Operative | 1965 |
[Acute hepatic lesion in a case of chloroform poisoning].
Topics: Adult; Chemical and Drug Induced Liver Injury; Chloroform; Humans; Liver Function Tests; Male | 1966 |