chlorocresol has been researched along with Central Core Disease in 2 studies
chlorocresol: injections for relief of intractable pain; RN given refers to parent cpd
4-chloro-m-cresol : A hydroxytoluene that is 3-methylphenol which is substituted by a chlorine at position 4. A ryanodine receptor agonist.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This disease is associated with malignant hyperthermia susceptibility and has been linked to the gene of skeletal muscle ryanodine receptor RYR1." | 1.32 | The Ile2453Thr mutation in the ryanodine receptor gene 1 is associated with facilitated calcium release from sarcoplasmic reticulum by 4-chloro-m-cresol in human myotubes. ( Koenig, F; Meinecke, CD; Olthoff, D; Rueffert, H; Wehner, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wehner, M | 1 |
| Rueffert, H | 1 |
| Koenig, F | 1 |
| Meinecke, CD | 1 |
| Olthoff, D | 1 |
| Ducreux, S | 1 |
| Zorzato, F | 1 |
| Ferreiro, A | 1 |
| Jungbluth, H | 1 |
| Muntoni, F | 1 |
| Monnier, N | 1 |
| Müller, CR | 1 |
| Treves, S | 1 |
2 other studies available for chlorocresol and Central Core Disease
| Article | Year |
|---|---|
The Ile2453Thr mutation in the ryanodine receptor gene 1 is associated with facilitated calcium release from sarcoplasmic reticulum by 4-chloro-m-cresol in human myotubes.
Topics: Adolescent; Adult; Aged; Calcium; Child; Cresols; Female; Genetic Predisposition to Disease; Humans; | 2003 |
Functional properties of ryanodine receptors carrying three amino acid substitutions identified in patients affected by multi-minicore disease and central core disease, expressed in immortalized lymphocytes.
Topics: Amino Acid Substitution; Caffeine; Calcium Signaling; Case-Control Studies; Cells, Cultured; Cresols | 2006 |