chloroacetic acid has been researched along with Coma in 2 studies
chloroacetic acid: urinary metabolite of vinyl chloride; RN given refers to parent cpd; structure
chloroacetic acid : A chlorocarboxylic acid that is acetic acid carrying a 2-chloro substituent.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Haber's Rule and associated time to coma after monochloroacetic acid (MCA) exposure in male Sprague-Dawley (SD) rats and time to death after 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in female Sprague-Dawley rats and male A/J mice were investigated at isoeffective or nearly isoeffective doses." | 3.73 | Validation of Haber's Rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state. ( Lebofsky, M; Pinson, DM; Rozman, KK; Saghir, SA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saghir, SA | 1 |
| Lebofsky, M | 1 |
| Pinson, DM | 1 |
| Rozman, KK | 1 |
| Raskin, W | 1 |
| Canada, A | 1 |
2 other studies available for chloroacetic acid and Coma
| Article | Year |
|---|---|
Validation of Haber's Rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state.
Topics: Acetates; Animals; Coma; Dioxins; Dose-Response Relationship, Drug; Female; Kinetics; Male; Mice; Mi | 2005 |
Acute topical exposure to a mixture of benzene, chloracetyl chloride and xylidine.
Topics: Acetates; Adult; Aniline Compounds; Benzene; Burns, Chemical; Coma; Humans; Male; Seizures; Solution | 1981 |