chloroacetic acid has been researched along with Chemical and Drug Induced Liver Injury in 3 studies
chloroacetic acid: urinary metabolite of vinyl chloride; RN given refers to parent cpd; structure
chloroacetic acid : A chlorocarboxylic acid that is acetic acid carrying a 2-chloro substituent.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Monochloroacetic acid (MCA) is a chlorination by-product of drinking water." | 1.30 | Interactive toxicity and stress protein expression by vinylidene chloride and monochloroacetate in precision-cut rat liver slices. ( Gandolfi, J; Wijeweera, J; Zheng, XH, 1998) |
| " Males pretreated with MCA had 45-fold greater plasma alanine aminotransferase (ALT) compared to the saline pretreated group similarly dosed with CHCl3." | 1.28 | Sex differences in monochloroacetate pretreatment effects on chloroform toxicity in rats. ( Berndt, WO; Davis, ME, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wijeweera, J | 1 |
| Gandolfi, J | 1 |
| Zheng, XH | 1 |
| Jaeger, RJ | 1 |
| Shoner, LG | 1 |
| Coffman, L | 1 |
| Davis, ME | 1 |
| Berndt, WO | 1 |
3 other studies available for chloroacetic acid and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Interactive toxicity and stress protein expression by vinylidene chloride and monochloroacetate in precision-cut rat liver slices.
Topics: Acetates; Animals; Blotting, Western; Chemical and Drug Induced Liver Injury; Dichloroethylenes; Dru | 1998 |
1,1-Dichloroethylene hepatotoxicity: proposed mechanism of action and distribution and binding of 14C radioactivity following inhalation exposure in rats.
Topics: Acetates; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Citrates; Dichloroethy | 1977 |
Sex differences in monochloroacetate pretreatment effects on chloroform toxicity in rats.
Topics: Acetates; Animals; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chloroform; Dichloro | 1992 |