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chlormezanone and Sleep Initiation and Maintenance Disorders

chlormezanone has been researched along with Sleep Initiation and Maintenance Disorders in 10 studies

Chlormezanone: A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
chlormezanone : A 1,3-thiazine that is 1,3-thiazinan-4-one S,S-dioxide in which a hydrogen at position 2 is substituted by a 4-chlorophenyl group and the hydrogen attached to the nitrogen is substituted by methyl. A non-benzodiazepine muscle relaxant, it was used in the management of anxiety and in the treatment of muscle spasms until being discontinued worldwide by its manufacturer in 1996, due to rare but serious cutaneous reactions.

Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.

Research Excerpts

ExcerptRelevanceReference
"Twenty-nine patients seen in general practice suffering from sleep disturbance due to mild neurotic anxiety were treated with 400 mg chlormezanone per night for 2 weeks."7.66Treatment of anxiety-related insomnia with chlormezanone. ( Ali-Khan, G, 1979)
"Twenty-nine patients seen in general practice suffering from sleep disturbance due to mild neurotic anxiety were treated with 400 mg chlormezanone per night for 2 weeks."3.66Treatment of anxiety-related insomnia with chlormezanone. ( Ali-Khan, G, 1979)
"Fifty-five patients complaining of insomnia entered a single-blind general practice study and were treated with either 400 mg chlormezanone or 20 mg temazepam at night for 2 weeks."2.65A comparison of chlormezanone and temazepam in sleep disturbance. ( Van Steenis, D, 1982)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Van Steenis, D1
Wojtulewski, JA1
Walter, J1
Clift, AD1
Burns, LE1
Hunter, GM1
Ghosh, AK1
Condie, R1
Cohen, L1
Warnock, JM1
Ali-Khan, G1
Rickels, K1
Pereira-Ogan, JA1
Case, WG1
Csanalosi, I1
Mirman, MJ1
Nathanson, JE1
Parish, LC1

Trials

7 trials available for chlormezanone and Sleep Initiation and Maintenance Disorders

ArticleYear
A comparison of chlormezanone and temazepam in sleep disturbance.
    Current medical research and opinion, 1982, Volume: 8, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Chlormezanone; Female; Humans; Male; Sleep Initiation and Maintenance Di

1982
Treatment of sleep disturbance in arthritis with chlormezanone.
    Current medical research and opinion, 1983, Volume: 8, Issue:7

    Topics: Arthritis, Rheumatoid; Chlormezanone; Clinical Trials as Topic; Double-Blind Method; Female; Humans;

1983
Hypnotics and hangovers: a pilot study of chlormezanone in general practice.
    The Journal of the Royal College of General Practitioners, 1982, Volume: 32, Issue:245

    Topics: Adult; Chlormezanone; Clinical Trials as Topic; Double-Blind Method; Family Practice; Female; Humans

1982
Two-dose comparison of chlormezanone in sleep disturbance due to anxiety.
    Current medical research and opinion, 1982, Volume: 8, Issue:1

    Topics: Anxiety Disorders; Chlormezanone; Clinical Trials as Topic; Double-Blind Method; Drug Administration

1982
A controlled study of Trancopal in sleep disturbances due to rheumatic disease.
    The Journal of international medical research, 1978, Volume: 6, Issue:2

    Topics: Adult; Aged; Chlormezanone; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female;

1978
A controlled study of Trancopal in the treatment of sleep disturbances due to anxiety.
    The Journal of international medical research, 1978, Volume: 6, Issue:2

    Topics: Adult; Aged; Anxiety; Chlormezanone; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation;

1978
Chlormezanone in anxiety: a drug rediscovered?
    The American journal of psychiatry, 1974, Volume: 131, Issue:5

    Topics: Administration, Oral; Adult; Ambulatory Care; Anxiety; Anxiety Disorders; Chlordiazepoxide; Chlormez

1974

Other Studies

3 other studies available for chlormezanone and Sleep Initiation and Maintenance Disorders

ArticleYear
Four-week tolerance study of chlormezanone for the treatment of insomnia in the elderly.
    The Journal of international medical research, 1982, Volume: 10, Issue:6

    Topics: Aged; Chlormezanone; Drug Evaluation; Female; Humans; Male; Sleep Initiation and Maintenance Disorde

1982
Chlormezanone in the treatment of insomnia due to rheumatic stiffness.
    Current medical research and opinion, 1979, Volume: 6, Issue:3

    Topics: Adult; Aged; Chlormezanone; Female; Humans; Male; Middle Aged; Rheumatic Diseases; Sleep Initiation

1979
Treatment of anxiety-related insomnia with chlormezanone.
    Current medical research and opinion, 1979, Volume: 6, Issue:4

    Topics: Adult; Aged; Anxiety; Chlormezanone; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Sc

1979