chlormezanone has been researched along with Acute Liver Injury, Drug-Induced in 8 studies
Chlormezanone: A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
chlormezanone : A 1,3-thiazine that is 1,3-thiazinan-4-one S,S-dioxide in which a hydrogen at position 2 is substituted by a 4-chlorophenyl group and the hydrogen attached to the nitrogen is substituted by methyl. A non-benzodiazepine muscle relaxant, it was used in the management of anxiety and in the treatment of muscle spasms until being discontinued worldwide by its manufacturer in 1996, due to rare but serious cutaneous reactions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 16 days previously she had started to take chlormezanone (Muskel Trancopal) and some other medications for pain in the shoulder and neck." | 3.70 | [Undesired drug effects after taking chlormezanone (Muscle Trancopal) with lethal results]. ( Breidenbach, K; Höhler, H; Köbberling, J; von Boxberg, C, 1998) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Chen, M | 2 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 3 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| von Boxberg, C | 1 |
| Breidenbach, K | 1 |
| Höhler, H | 1 |
| Köbberling, J | 1 |
| Ohsawa, T | 1 |
| Konishi, K | 1 |
| Pomiersky, C | 1 |
| Blaich, E | 1 |
1 review available for chlormezanone and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
7 other studies available for chlormezanone and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
[Undesired drug effects after taking chlormezanone (Muscle Trancopal) with lethal results].
Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Chlormezanone; Colon; Fatal Outcome; F | 1998 |
[The Lobac overview: little risk of adverse effects. Effects on skin and liver are the most common and the most severe].
Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Chlormezanone; Drug Combinations; Humans; Ris | 1991 |
Hepatitis associated with chlormezanone.
Topics: Aged; Chemical and Drug Induced Liver Injury; Chlormezanone; Drug Hypersensitivity; Female; Humans | 1986 |
[Drug-induced hepatitis with cholestasis following therapy with chlormezanone].
Topics: Arthritis, Rheumatoid; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Chlormezanone; Choles | 1985 |