chlormethiazole has been researched along with Nerve Degeneration in 8 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (62.50) | 18.2507 |
2000's | 2 (25.00) | 29.6817 |
2010's | 1 (12.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Luo, J; Pepperberg, DR; Qin, Z; Tavassoli, E; Thatcher, GR; Vandevrede, L; Yue, L | 1 |
Green, AR; Hewitt, KE | 1 |
Cross, AJ; Green, AR; Sydserff, SG | 1 |
Colado, MI; Esteban, B; Granados, R; Green, AR; O'Shea, E | 2 |
Cross, AJ; Green, AR; Jones, JA; Misra, A; Murray, TK; Snape, MF | 1 |
Camarero, J; Colado, MI; Elliott, JM; Esteban, B; Green, AR; Mechan, AO; Sanchez, V | 1 |
Baldwin, HA; Cross, AJ; Green, AR; Jones, JA | 1 |
8 other study(ies) available for chlormethiazole and Nerve Degeneration
Article | Year |
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Novel analogues of chlormethiazole are neuroprotective in four cellular models of neurodegeneration by a mechanism with variable dependence on GABA(A) receptor potentiation.
Topics: Animals; Biological Availability; Brain; Calcium; Cell Hypoxia; Chlormethiazole; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Oocytes; Pregnancy; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Xenopus laevis | 2014 |
Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats.
Topics: Animals; Chlormethiazole; Dizocilpine Maleate; Haloperidol; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Endings; Neuroprotective Agents; Radioligand Assay; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin | 1994 |
The effect of oedema and tissue swelling on the measurement of neuroprotection; a study using chlormethiazole and permanent middle cerebral artery occlusion in rats.
Topics: Animals; Body Water; Brain; Brain Edema; Brain Ischemia; Cerebral Arteries; Chlormethiazole; Male; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Inbred Strains; Regression Analysis | 1996 |
Role of hyperthermia in the protective action of clomethiazole against MDMA ('ecstasy')-induced neurodegeneration, comparison with the novel NMDA channel blocker AR-R15896AR.
Topics: Animals; Body Temperature; Brain Chemistry; Chlormethiazole; Excitatory Amino Acid Antagonists; Fever; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Neuroprotective Agents; Paroxetine; Pyridines; Rats; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Serotonin | 1998 |
In vivo evidence against clomethiazole being neuroprotective against MDMA ('ecstasy')-induced degeneration of rat brain 5-HT nerve terminals by a free radical scavenging mechanism.
Topics: Animals; Biotransformation; Body Temperature; Brain; Cerebral Cortex; Chlormethiazole; Corpus Striatum; Free Radical Scavengers; Gentisates; Hippocampus; Hydroxybenzoates; Hydroxyindoleacetic Acid; Kinetics; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Endings; Neuroprotective Agents; Paroxetine; Rats; Salicylic Acid; Serotonin | 1999 |
The metabolism of clomethiazole in gerbils and the neuroprotective and sedative activity of the metabolites.
Topics: Animals; Brain; Brain Ischemia; Chlormethiazole; Gerbillinae; Hypnotics and Sedatives; Male; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Thiazoles | 2000 |
A study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brain.
Topics: Animals; Chlormethiazole; Corpus Striatum; Cyclic N-Oxides; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fever; Free Radicals; Hydroxybenzoates; Injections, Intraperitoneal; Male; Mice; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitrogen Oxides; Pyridines; Salicylic Acid | 2001 |
Neuroprotective activity of chlormethiazole following transient forebrain ischaemia in the gerbil.
Topics: Animals; Body Temperature; Chlormethiazole; Drug Synergism; gamma-Aminobutyric Acid; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Nerve Degeneration; Neurons; Prosencephalon | 1991 |