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chlormethiazole and Nerve Degeneration

chlormethiazole has been researched along with Nerve Degeneration in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Luo, J; Pepperberg, DR; Qin, Z; Tavassoli, E; Thatcher, GR; Vandevrede, L; Yue, L1
Green, AR; Hewitt, KE1
Cross, AJ; Green, AR; Sydserff, SG1
Colado, MI; Esteban, B; Granados, R; Green, AR; O'Shea, E2
Cross, AJ; Green, AR; Jones, JA; Misra, A; Murray, TK; Snape, MF1
Camarero, J; Colado, MI; Elliott, JM; Esteban, B; Green, AR; Mechan, AO; Sanchez, V1
Baldwin, HA; Cross, AJ; Green, AR; Jones, JA1

Other Studies

8 other study(ies) available for chlormethiazole and Nerve Degeneration

ArticleYear
Novel analogues of chlormethiazole are neuroprotective in four cellular models of neurodegeneration by a mechanism with variable dependence on GABA(A) receptor potentiation.
    British journal of pharmacology, 2014, Volume: 171, Issue:2

    Topics: Animals; Biological Availability; Brain; Calcium; Cell Hypoxia; Chlormethiazole; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Oocytes; Pregnancy; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Xenopus laevis

2014
Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats.
    Neuropharmacology, 1994, Volume: 33, Issue:12

    Topics: Animals; Chlormethiazole; Dizocilpine Maleate; Haloperidol; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Endings; Neuroprotective Agents; Radioligand Assay; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin

1994
The effect of oedema and tissue swelling on the measurement of neuroprotection; a study using chlormethiazole and permanent middle cerebral artery occlusion in rats.
    Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration, 1996, Volume: 5, Issue:1

    Topics: Animals; Body Water; Brain; Brain Edema; Brain Ischemia; Cerebral Arteries; Chlormethiazole; Male; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Inbred Strains; Regression Analysis

1996
Role of hyperthermia in the protective action of clomethiazole against MDMA ('ecstasy')-induced neurodegeneration, comparison with the novel NMDA channel blocker AR-R15896AR.
    British journal of pharmacology, 1998, Volume: 124, Issue:3

    Topics: Animals; Body Temperature; Brain Chemistry; Chlormethiazole; Excitatory Amino Acid Antagonists; Fever; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Neuroprotective Agents; Paroxetine; Pyridines; Rats; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Serotonin

1998
In vivo evidence against clomethiazole being neuroprotective against MDMA ('ecstasy')-induced degeneration of rat brain 5-HT nerve terminals by a free radical scavenging mechanism.
    Neuropharmacology, 1999, Volume: 38, Issue:2

    Topics: Animals; Biotransformation; Body Temperature; Brain; Cerebral Cortex; Chlormethiazole; Corpus Striatum; Free Radical Scavengers; Gentisates; Hippocampus; Hydroxybenzoates; Hydroxyindoleacetic Acid; Kinetics; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Endings; Neuroprotective Agents; Paroxetine; Rats; Salicylic Acid; Serotonin

1999
The metabolism of clomethiazole in gerbils and the neuroprotective and sedative activity of the metabolites.
    British journal of pharmacology, 2000, Volume: 129, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Chlormethiazole; Gerbillinae; Hypnotics and Sedatives; Male; Motor Activity; Nerve Degeneration; Neuroprotective Agents; Thiazoles

2000
A study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brain.
    British journal of pharmacology, 2001, Volume: 134, Issue:8

    Topics: Animals; Chlormethiazole; Corpus Striatum; Cyclic N-Oxides; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fever; Free Radicals; Hydroxybenzoates; Injections, Intraperitoneal; Male; Mice; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitrogen Oxides; Pyridines; Salicylic Acid

2001
Neuroprotective activity of chlormethiazole following transient forebrain ischaemia in the gerbil.
    British journal of pharmacology, 1991, Volume: 104, Issue:2

    Topics: Animals; Body Temperature; Chlormethiazole; Drug Synergism; gamma-Aminobutyric Acid; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Nerve Degeneration; Neurons; Prosencephalon

1991