chlormethiazole has been researched along with Disease Models, Animal in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 9 (60.00) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Chen, YY; Xie, KQ; Zeng, T; Zhang, CL; Zhao, XL | 1 |
| Arancio, O; Asghodom, RT; Ben Aissa, M; Fà, M; Lee, SH; Luo, J; Pepperberg, DR; Piyankarage, S; Qin, Z; Tavassoli, E; Thatcher, GR; VandeVrede, L; Yue, L | 1 |
| Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T | 1 |
| Marshall, JW; Ridley, RM | 1 |
| Green, AR; Marshall, JW; Ridley, RM | 1 |
| Chaulk, D; Corbett, D; Evans, S; Jackson, D; Wells, J | 1 |
| Bardag-Gorce, F; French, BA; French, SW; Li, J; Lue, YH; Montgomery, RO; Nan, L; Riley, NE | 1 |
| Appleton, I; Clarkson, AN; Jackson, DM; Kerr, DS; Liu, H; Rahman, R | 1 |
| Forsberg, T; Gabrielsson, J; Peletier, LA; Sällström, B; Visser, SA | 1 |
| Cross, AJ; Green, AR; Sydserff, SG; West, KJ | 1 |
| Green, AR | 1 |
| Cross, AJ; Green, AR; Jones, JA; Murray, TK; Sydserff, SG | 1 |
| Donohue, TM; Fang, C; French, BA; French, SW; Fu, P; Gouillon, Z; Hagbjork, AL; Ingelman-Sundberg, M; Li, J; Lucas, D | 1 |
2 review(s) available for chlormethiazole and Disease Models, Animal
| Article | Year |
|---|---|
Assessment of cognitive and motor deficits in a marmoset model of stroke.
Topics: Animals; Behavior, Animal; Benzenesulfonates; Callithrix; Chlormethiazole; Cognition; Disease Models, Animal; Female; Male; Motor Activity; Neuroprotective Agents; Nitrogen Oxides; Psychomotor Performance; Pyridines; Recovery of Function; Stroke | 2003 |
Clomethiazole (Zendra) in acute ischemic stroke: basic pharmacology and biochemistry and clinical efficacy.
Topics: Animals; Brain Ischemia; Chlormethiazole; Disease Models, Animal; Humans; Models, Chemical; Neuroprotective Agents; Neurotoxins | 1998 |
13 other study(ies) available for chlormethiazole and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Inhibition of cytochrome P4502E1 by chlormethiazole attenuated acute ethanol-induced fatty liver.
Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Autophagy; Carbon-Carbon Ligases; Chlormethiazole; Cytochrome P-450 CYP2E1 Inhibitors; Diacylglycerol O-Acyltransferase; Disease Models, Animal; Fatty Acid Synthases; Fatty Liver, Alcoholic; Male; Mice; Oxidative Stress; Phosphorylation; PPAR alpha; RNA, Messenger; Sterol Regulatory Element Binding Protein 1 | 2014 |
Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia.
Topics: Alzheimer Disease; Animals; Chlormethiazole; CREB-Binding Protein; Cyclic GMP; Disease Models, Animal; Drug Repositioning; GABA-A Receptor Agonists; Hippocampus; Long-Term Potentiation; Male; Mice; Mice, Transgenic; Neuroprotective Agents; Nitric Oxide; Nootropic Agents; Signal Transduction; Synapses; Xenopus laevis | 2015 |
Diazepam and chlormethiazole attenuate the development of hyperthermia in an animal model of the serotonin syndrome.
Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Brain; Chlormethiazole; Clorgyline; Diazepam; Disease Models, Animal; Fever; Kinetics; Male; Microdialysis; Neuroprotective Agents; Rats; Rats, Wistar; Serotonin Syndrome; Time Factors | 2003 |
Comparison of the neuroprotective effect of clomethiazole, AR-R15896AR and NXY-059 in a primate model of stroke using histological and behavioural measures.
Topics: Animals; Behavior, Animal; Benzenesulfonates; Callithrix; Cerebral Cortex; Chlormethiazole; Disease Models, Animal; Drug Administration Routes; Evaluation Studies as Topic; Extinction, Psychological; Motor Activity; Neostriatum; Neuroprotective Agents; Nitrogen Oxides; Pyridines; Space Perception; Stereotaxic Techniques; Stroke; Time Factors | 2003 |
Long-term effects of clomethiazole in a model of global ischemia.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Brain Ischemia; Cell Count; Chlormethiazole; Disease Models, Animal; Disease Progression; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Gerbillinae; Hippocampus; In Vitro Techniques; Neurons; Neuroprotective Agents; Spatial Behavior; Time | 2003 |
The proteasome inhibitor, PS-341, causes cytokeratin aggresome formation.
Topics: Actins; Animals; Boronic Acids; Bortezomib; Cell Membrane; Cells, Cultured; Chlormethiazole; Dicarbethoxydihydrocollidine; Disease Models, Animal; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Fluorescent Antibody Technique, Indirect; Hepatocytes; Inclusion Bodies; Keratins; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Microscopy, Confocal; Phosphoproteins; Protease Inhibitors; Pyrazines; Zonula Occludens-1 Protein | 2004 |
Clomethiazole: mechanisms underlying lasting neuroprotection following hypoxia-ischemia.
Topics: Animals; Arginase; Brain; Carotid Arteries; Chlormethiazole; Disease Models, Animal; Electrophysiology; Evoked Potentials; Hypoxia-Ischemia, Brain; Ligation; Male; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, GABA; Time Factors | 2005 |
Modeling drug- and system-related changes in body temperature: application to clomethiazole-induced hypothermia, long-lasting tolerance development, and circadian rhythm in rats.
Topics: Animals; Body Temperature; Chlormethiazole; Circadian Rhythm; Disease Models, Animal; Drug Tolerance; Hypnotics and Sedatives; Hypothermia; Male; Rats; Rats, Sprague-Dawley | 2006 |
The effect of chlormethiazole on neuronal damage in a model of transient focal ischaemia.
Topics: Animals; Blood Pressure; Cell Death; Cerebral Cortex; Cerebrovascular Disorders; Chlormethiazole; Corpus Striatum; Disease Models, Animal; Heart Rate; Ischemic Attack, Transient; Male; Neurons; Rats; Time Factors | 1995 |
Clomethiazole is neuroprotective in models of global and focal cerebral ischemia when infused at doses producing clinically relevant plasma concentrations.
Topics: Animals; Arterial Occlusive Diseases; Chlormethiazole; Disease Models, Animal; Dose-Response Relationship, Drug; Gerbillinae; Infarction, Middle Cerebral Artery; Infusions, Intravenous; Ischemic Attack, Transient; Male; Neuroprotective Agents; Prosencephalon; Rats; Rats, Long-Evans | 2000 |
Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole.
Topics: Animals; Apoenzymes; Body Weight; Chlormethiazole; Chlorzoxazone; Chymotrypsin; Cysteine Endopeptidases; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Disease Models, Animal; Ethanol; Hydroxylation; Immunohistochemistry; Liver; Liver Diseases, Alcoholic; Male; Multienzyme Complexes; Organ Size; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Trypsin | 2000 |