Page last updated: 2024-08-21

chlormethiazole and Apoplexy

chlormethiazole has been researched along with Apoplexy in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.00)18.2507
2000's14 (70.00)29.6817
2010's4 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, J; Wang, LN; Zhang, J1
Liu, J; Wang, LN2
Ji, X; Liu, J; Ma, X; Wang, LN1
Carlsson, KC; Hooker, AC; Karlsson, MO; Savić, RM1
Lutsep, HL; Vaishnav, A1
Marshall, JW; Ridley, RM1
Green, AR; Marshall, JW; Ridley, RM1
Ashwood, T; Ekblom, M; Jonsson, EN; Karlsson, MO; Lyden, P; Odergren, T; Zingmark, PH1
Hess, DC1
Caster, O; Jonsson, EN; Nyberg, J; Ribbing, J1
Bankhead, C1
Arboix, A; Ashwood, T; Díez-Tejedor, E; Grossman, E; Leys, D; Teitelbaum, J; Wahlgren, NG1
Baker, HF; Cross, AJ; Green, AR; Jackson, DM; Marshall, JW; Ridley, RM1
Cross, AJ; Gabrielsson, J; Green, AR; Hainsworth, AH; Jones, JA; Lambert, DG; Murray, TK; Nelson, RM; Richards, DA1
Albers, G; Ashwood, T; Jacoby, M; Lyden, P; Mazzeo, P; Nordlund, A; Odergren, T; Schim, J1
Ashwood, T; Atkinson, RP; Claesson, L; Levin, K; Lyden, P; Ng, K; Odergren, T; Rajput, A; Salazar-Grueso, E; Shuaib, A; Wechsler, L1
Hankey, GJ1
Sareen, D1

Reviews

7 review(s) available for chlormethiazole and Apoplexy

ArticleYear
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke.
    The Cochrane database of systematic reviews, 2018, 10-30, Volume: 10

    Topics: Acute Disease; Chlormethiazole; Diazepam; Disorders of Excessive Somnolence; GABA Agonists; gamma-Aminobutyric Acid; Humans; Neuroprotective Agents; Randomized Controlled Trials as Topic; Rhinitis; Stroke

2018
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke.
    The Cochrane database of systematic reviews, 2013, Feb-28, Issue:2

    Topics: Chlormethiazole; Diazepam; GABA Agonists; Humans; Neuroprotective Agents; Randomized Controlled Trials as Topic; Stroke

2013
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke.
    The Cochrane database of systematic reviews, 2014, Aug-06, Issue:8

    Topics: Acute Disease; Chlormethiazole; Diazepam; Disorders of Excessive Somnolence; GABA Agonists; Humans; Neuroprotective Agents; Randomized Controlled Trials as Topic; Rhinitis; Stroke

2014
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke.
    The Cochrane database of systematic reviews, 2016, Oct-04, Volume: 10

    Topics: Acute Disease; Chlormethiazole; Diazepam; Disorders of Excessive Somnolence; GABA Agonists; Humans; Neuroprotective Agents; Randomized Controlled Trials as Topic; Rhinitis; Stroke

2016
GABA agonist: clomethiazole.
    Current medical research and opinion, 2002, Volume: 18 Suppl 2

    Topics: Chlormethiazole; GABA Modulators; GABA-A Receptor Agonists; Humans; Neuroprotective Agents; Stroke

2002
Assessment of cognitive and motor deficits in a marmoset model of stroke.
    ILAR journal, 2003, Volume: 44, Issue:2

    Topics: Animals; Behavior, Animal; Benzenesulfonates; Callithrix; Chlormethiazole; Cognition; Disease Models, Animal; Female; Male; Motor Activity; Neuroprotective Agents; Nitrogen Oxides; Psychomotor Performance; Pyridines; Recovery of Function; Stroke

2003
Neuroprotective agents in acute ischemic stroke.
    The Journal of the Association of Physicians of India, 2002, Volume: 50

    Topics: Acute Disease; Adult; Aged; Animals; Antioxidants; Calcium Channel Blockers; Chlormethiazole; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Forecasting; GABA Modulators; Guanidines; Humans; Imidazoles; Middle Aged; Naltrexone; Narcotic Antagonists; Neuroprotective Agents; Pipecolic Acids; Piperidines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Stroke; Thiazoles

2002

Trials

4 trial(s) available for chlormethiazole and Apoplexy

ArticleYear
Population pharmacokinetics of clomethiazole and its effect on the natural course of sedation in acute stroke patients.
    British journal of clinical pharmacology, 2003, Volume: 56, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Chlormethiazole; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Middle Aged; Regression Analysis; Stroke

2003
Results in 95 hemorrhagic stroke patients included in CLASS, a controlled trial of clomethiazole versus placebo in acute stroke patients.
    Stroke, 2000, Volume: 31, Issue:1

    Topics: Acute Disease; Aged; Chlormethiazole; Female; Humans; Infusions, Intravenous; Intracranial Hemorrhages; Male; Middle Aged; Neuroprotective Agents; Stroke

2000
The Clomethiazole Acute Stroke Study in tissue-type plasminogen activator-treated stroke (CLASS-T): final results.
    Neurology, 2001, Oct-09, Volume: 57, Issue:7

    Topics: Acute Disease; Aged; Brain Ischemia; Chlormethiazole; Double-Blind Method; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Neuroprotective Agents; Stroke; Tissue Plasminogen Activator; Treatment Outcome

2001
Clomethiazole Acute Stroke Study in ischemic stroke (CLASS-I): final results.
    Stroke, 2002, Volume: 33, Issue:1

    Topics: Acute Disease; Adult; Aged; Brain Ischemia; Chlormethiazole; Double-Blind Method; Female; GABA Modulators; Humans; Male; Middle Aged; Neuroprotective Agents; Stroke; Time Factors

2002

Other Studies

9 other study(ies) available for chlormethiazole and Apoplexy

ArticleYear
Modeling subpopulations with the $MIXTURE subroutine in NONMEM: finding the individual probability of belonging to a subpopulation for the use in model analysis and improved decision making.
    The AAPS journal, 2009, Volume: 11, Issue:1

    Topics: Algorithms; Anticonvulsants; Chlormethiazole; Computer Simulation; Decision Making; Decision Support Techniques; Epilepsy; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Likelihood Functions; Monitoring, Physiologic; Nonlinear Dynamics; Patients; Poisson Distribution; Pregabalin; Probability; Randomized Controlled Trials as Topic; Software; Stroke

2009
Comparison of the neuroprotective effect of clomethiazole, AR-R15896AR and NXY-059 in a primate model of stroke using histological and behavioural measures.
    Brain research, 2003, May-16, Volume: 972, Issue:1-2

    Topics: Animals; Behavior, Animal; Benzenesulfonates; Callithrix; Cerebral Cortex; Chlormethiazole; Disease Models, Animal; Drug Administration Routes; Evaluation Studies as Topic; Extinction, Psychological; Motor Activity; Neostriatum; Neuroprotective Agents; Nitrogen Oxides; Pyridines; Space Perception; Stereotaxic Techniques; Stroke; Time Factors

2003
NXY-059: a hopeful sign in the treatment of stroke.
    Stroke, 2006, Volume: 37, Issue:10

    Topics: Animals; Benzenesulfonates; Callithrix; Chlormethiazole; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Fibrinolytic Agents; Free Radical Scavengers; Hemorrhage; Humans; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Nitrogen Oxides; Pyridines; Randomized Controlled Trials as Topic; Research Design; Rodentia; Stroke; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome

2006
The lasso--a novel method for predictive covariate model building in nonlinear mixed effects models.
    Journal of pharmacokinetics and pharmacodynamics, 2007, Volume: 34, Issue:4

    Topics: Algorithms; Chlormethiazole; Computer Simulation; Humans; Linear Models; Models, Statistical; Neuroprotective Agents; Nonlinear Dynamics; Pharmacokinetics; Regression Analysis; Stroke

2007
Clomethiazole. Chlormethiazole, Zendra.
    Drugs in R&D, 1999, Volume: 1, Issue:1

    Topics: Animals; Chlormethiazole; Drugs, Investigational; Gerbillinae; Humans; Neuroprotective Agents; Stroke

1999
What's new with neuroprotective agents in stroke?
    Drugs in R&D, 1999, Volume: 1, Issue:1

    Topics: Animals; Chlormethiazole; Cytidine Diphosphate Choline; Drugs, Investigational; Humans; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles

1999
Clomethiazole protects against hemineglect in a primate model of stroke.
    Brain research bulletin, 2000, May-01, Volume: 52, Issue:1

    Topics: Animals; Attention; Behavior, Animal; Brain; Callithrix; Chlormethiazole; Choice Behavior; GABA Modulators; Movement Disorders; Neuroprotective Agents; Stroke

2000
Neuroprotective efficacy of AR-A008055, a clomethiazole analogue, in a global model of acute ischaemic stroke and its effect on ischaemia-induced glutamate and GABA efflux in vitro.
    Neuropharmacology, 2001, Volume: 41, Issue:2

    Topics: Animals; Brain Ischemia; Chlormethiazole; Female; gamma-Aminobutyric Acid; Gerbillinae; Glutamic Acid; Hippocampus; Male; Methylamines; Neuroprotective Agents; Rats; Rats, Wistar; Stroke; Thiazoles

2001
Clomethiazole: an unsuccessful bachelor, but perhaps a prosperous married man?
    Stroke, 2002, Volume: 33, Issue:1

    Topics: Acute Disease; Animals; Brain Ischemia; Chlormethiazole; Clinical Trials as Topic; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Neuroprotective Agents; Stroke; Tissue Plasminogen Activator

2002