Page last updated: 2024-08-21

chlormethiazole and Alcoholic Liver Diseases

chlormethiazole has been researched along with Alcoholic Liver Diseases in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Bruckner, T; Burhenne, J; Haefeli, WE; Hohmann, N; Moreira, B; Mueller, S; Schröder, F; Seitz, HK; Teng, H2
Seitz, HK1
Badger, TM; Fang, C; Ingelman-Sundberg, M; Lindros, KO; Ronis, MJ1
Donohue, TM; Fang, C; French, BA; French, SW; Fu, P; Gouillon, Z; Hagbjork, AL; Ingelman-Sundberg, M; Li, J; Lucas, D1
Gayford, JJ; Milne, S; Wylie, AS1
Hoensch, HP1

Reviews

1 review(s) available for chlormethiazole and Alcoholic Liver Diseases

ArticleYear
The role of cytochrome P4502E1 in the pathogenesis of alcoholic liver disease and carcinogenesis.
    Chemico-biological interactions, 2020, Jan-25, Volume: 316

    Topics: Alcoholic Intoxication; Animals; Carcinogenesis; Cell Line, Tumor; Chlormethiazole; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Ethanol; Humans; Liver Cirrhosis; Liver Diseases, Alcoholic; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Tretinoin; Vitamin A

2020

Trials

1 trial(s) available for chlormethiazole and Alcoholic Liver Diseases

ArticleYear
Effect of Clomethiazole Vs. Clorazepate on Hepatic Fat and Serum Transaminase Activities in Alcohol-Associated Liver Disease: Results from a Randomized, Controlled Phase II Clinical Trial.
    Alcohol and alcoholism (Oxford, Oxfordshire), 2023, Mar-10, Volume: 58, Issue:2

    Topics: Alanine Transaminase; Alcoholism; Animals; Chlormethiazole; Clorazepate Dipotassium; Cytochrome P-450 CYP2E1; Ethanol; Fatty Liver; Humans; Liver; Liver Diseases, Alcoholic; Reactive Oxygen Species; Transaminases

2023

Other Studies

5 other study(ies) available for chlormethiazole and Alcoholic Liver Diseases

ArticleYear
Clomethiazole inhibits cytochrome P450 2E1 and improves alcoholic liver disease.
    Gut, 2022, Volume: 71, Issue:4

    Topics: Chlormethiazole; Cytochrome P-450 CYP2E1; Ethanol; Humans; Liver Diseases, Alcoholic

2022
Zonated expression of cytokines in rat liver: effect of chronic ethanol and the cytochrome P450 2E1 inhibitor, chlormethiazole.
    Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:5

    Topics: Animals; Chlormethiazole; Cytochrome P-450 CYP2E1 Inhibitors; Cytokines; Ethanol; Gene Expression; Interleukin-1; Interleukins; Liver; Liver Diseases, Alcoholic; Male; Rats; Rats, Sprague-Dawley; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

1998
Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 2000, Volume: 224, Issue:4

    Topics: Animals; Apoenzymes; Body Weight; Chlormethiazole; Chlorzoxazone; Chymotrypsin; Cysteine Endopeptidases; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Disease Models, Animal; Ethanol; Hydroxylation; Immunohistochemistry; Liver; Liver Diseases, Alcoholic; Male; Multienzyme Complexes; Organ Size; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Trypsin

2000
Physical morbidity in patients admitted for detoxification from alcohol.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1991, Volume: 26, Issue:5-6

    Topics: Adult; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Chlormethiazole; Erythrocyte Indices; Female; Follow-Up Studies; Humans; Liver Diseases, Alcoholic; Liver Function Tests; Male; Middle Aged; Substance Abuse Treatment Centers

1991
Effect of chlormethiazole on the hepatic monooxygenase enzyme system.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 329

    Topics: Adult; Chlormethiazole; Coumarins; Enzyme Induction; Female; Humans; Liver; Liver Diseases, Alcoholic; Male; Oxygenases; Umbelliferones

1986