chlorine has been researched along with Spinal Cord Injuries in 21 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current anti-spastic medication significantly compromises motor recovery after spinal cord injury (SCI), indicating a critical need for alternative interventions." | 1.91 | Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition with step-training. ( Bilchak, J; Caron, G; Côté, MP, 2023) |
| "At the cellular level, spasticity is considered to be primarily caused by the hyperexcitability of spinal α-motoneurons (MNs) within the spinal stretch reflex circuit." | 1.72 | Molecular Identification of Pro-Excitogenic Receptor and Channel Phenotypes of the Deafferented Lumbar Motoneurons in the Early Phase after SCT in Rats. ( Ji, B; Skup, M; Wojtaś, B, 2022) |
| "Unlike current anti-spastic pharmacological treatments, rehabilitation attenuates spastic symptoms without causing an active depression in spinal excitability, thus avoiding further interference with motor recovery." | 1.56 | Rehabilitation Decreases Spasticity by Restoring Chloride Homeostasis through the Brain-Derived Neurotrophic Factor-KCC2 Pathway after Spinal Cord Injury. ( Beverungen, H; Côté, MP; Klaszky, M; Klaszky, SC, 2020) |
| "Hydrogen has been deemed as a novel antioxidant." | 1.40 | Molecular hydrogen suppresses reactive astrogliosis related to oxidative injury during spinal cord injury in rats. ( Li, J; Li, XN; Liu, FT; Sun, XJ; Xiang, ZH; Xu, SM; Yuan, HB, 2014) |
| "Sprague Dawley rats received a spinal cord transection at T12 and were assigned to SCI-7d, SCI-14d, SCI-14d+exercise, SCI-28d, SCI-28d+exercise, or SCI-56d groups." | 1.40 | Exercise modulates chloride homeostasis after spinal cord injury. ( Côté, MP; Gandhi, S; Houlé, JD; Zambrotta, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 4 (19.05) | 2.80 |
| Authors | Studies |
|---|---|
| Hudson, KE | 1 |
| Grau, JW | 1 |
| Ji, B | 1 |
| Wojtaś, B | 1 |
| Skup, M | 1 |
| Caron, G | 1 |
| Bilchak, J | 1 |
| Côté, MP | 3 |
| Beverungen, H | 1 |
| Klaszky, SC | 1 |
| Klaszky, M | 1 |
| Tillman, L | 1 |
| Zhang, J | 1 |
| Liu, FT | 1 |
| Xu, SM | 1 |
| Xiang, ZH | 1 |
| Li, XN | 1 |
| Li, J | 1 |
| Yuan, HB | 1 |
| Sun, XJ | 1 |
| Gandhi, S | 1 |
| Zambrotta, M | 1 |
| Houlé, JD | 1 |
| Gackière, F | 1 |
| Vinay, L | 4 |
| Shen, XF | 1 |
| Zhao, Y | 1 |
| Zhang, YK | 1 |
| Jia, LY | 1 |
| Ju, G | 1 |
| Martirosyan, NL | 1 |
| Bennett, KM | 1 |
| Theodore, N | 1 |
| Preul, MC | 1 |
| Boulenguez, P | 3 |
| Liabeuf, S | 3 |
| Viemari, JC | 1 |
| Bos, R | 2 |
| Brocard, C | 2 |
| Brocard, F | 1 |
| Bras, H | 2 |
| Coulon, P | 1 |
| Pearlstein, E | 1 |
| Sadlaoud, K | 2 |
| Stil, A | 1 |
| Tazerart, S | 1 |
| Buttigieg, D | 1 |
| Haase, G | 1 |
| Stieltjes, B | 2 |
| Klussmann, S | 1 |
| Bock, M | 1 |
| Umathum, R | 1 |
| Mangalathu, J | 1 |
| Letellier, E | 1 |
| Rittgen, W | 1 |
| Edler, L | 1 |
| Krammer, PH | 1 |
| Kauczor, HU | 1 |
| Martin-Villalba, A | 1 |
| Essig, M | 2 |
| Bonny, JM | 1 |
| Mailly, P | 1 |
| Renou, JP | 1 |
| Orsal, D | 1 |
| Benmoussa, A | 1 |
| Stettler, O | 1 |
| Walder, N | 1 |
| Petter-Puchner, AH | 1 |
| Brejnikow, M | 1 |
| Redl, H | 1 |
| Vaziri, ND | 1 |
| Bruno, A | 1 |
| Byrne, C | 1 |
| Mirahmadi, MK | 1 |
| Nikakhtar, B | 1 |
| Gordon, S | 1 |
| Zeien, L | 1 |
| Fehlings, MG | 2 |
| Nashmi, R | 2 |
| Liu, D | 1 |
| Sybert, TE | 1 |
| Qian, H | 1 |
| Liu, J | 1 |
| Jones, OT | 1 |
| Anderson, DK | 1 |
| Prockop, LD | 1 |
| Means, ED | 1 |
| Hartley, LE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Adjuvant Therapy for Severe COPD Patients in the Stable Phase by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study[NCT02850185] | 170 participants (Anticipated) | Interventional | 2016-07-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for chlorine and Spinal Cord Injuries
| Article | Year |
|---|---|
Ionic Plasticity: Common Mechanistic Underpinnings of Pathology in Spinal Cord Injury and the Brain.
Topics: Brain; Chlorides; gamma-Aminobutyric Acid; Humans; Potassium; Receptors, GABA-A; Spinal Cord Injurie | 2022 |
Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K
Topics: Central Nervous System; Chloride Channels; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Gene Target | 2019 |
Chapter 1--importance of chloride homeostasis in the operation of rhythmic motor networks.
Topics: Animals; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Homeostasis; Locomotion; Memb | 2011 |
18 other studies available for chlorine and Spinal Cord Injuries
| Article | Year |
|---|---|
Molecular Identification of Pro-Excitogenic Receptor and Channel Phenotypes of the Deafferented Lumbar Motoneurons in the Early Phase after SCT in Rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chlorides; gamma-Aminobutyric Aci | 2022 |
Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition with step-training.
Topics: Animals; Bumetanide; Chlorides; Motor Neurons; Muscle Spasticity; Rats; Spinal Cord; Spinal Cord Inj | 2023 |
Rehabilitation Decreases Spasticity by Restoring Chloride Homeostasis through the Brain-Derived Neurotrophic Factor-KCC2 Pathway after Spinal Cord Injury.
Topics: Animals; Brain-Derived Neurotrophic Factor; Chlorides; Female; H-Reflex; Homeostasis; K Cl- Cotransp | 2020 |
Molecular hydrogen suppresses reactive astrogliosis related to oxidative injury during spinal cord injury in rats.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Proliferation; Cells, Cultured; Chlorides; Cytokines; En | 2014 |
Exercise modulates chloride homeostasis after spinal cord injury.
Topics: Acetates; Animals; Brain-Derived Neurotrophic Factor; Bumetanide; Chloride Channels; Chlorides; Cord | 2014 |
Contribution of the potassium-chloride cotransporter KCC2 to the strength of inhibition in the neonatal rodent spinal cord in vitro.
Topics: Animals; Chlorides; Down-Regulation; K Cl- Cotransporters; Membrane Potentials; Mice; Mice, Transgen | 2015 |
A modified ferric tannate method for visualizing a blood vessel and its usage in the study of spinal cord injury.
Topics: Animals; Biomarkers; Blood Vessels; Chlorides; Coloring Agents; Disease Models, Animal; Ferric Compo | 2009 |
Manganese-enhanced magnetic resonance imaging in experimental spinal cord injury: correlation between T1-weighted changes and Mn(2+) concentrations.
Topics: Animals; Chlorides; Disease Models, Animal; Female; Image Enhancement; Magnetic Resonance Imaging; M | 2010 |
[Reduced neuronal inhibition and spasticity following spinal cord injury].
Topics: Animals; Brain-Derived Neurotrophic Factor; Chlorides; gamma-Aminobutyric Acid; Glycine; H-Reflex; H | 2011 |
Activation of 5-HT2A receptors upregulates the function of the neuronal K-Cl cotransporter KCC2.
Topics: Animals; Blotting, Western; Bridged Bicyclo Compounds; Chlorides; Gene Expression Regulation; H-Refl | 2013 |
Manganese-enhanced magnetic resonance imaging for in vivo assessment of damage and functional improvement following spinal cord injury in mice.
Topics: Algorithms; Animals; Chlorides; Contrast Media; Image Enhancement; Image Interpretation, Computer-As | 2006 |
Analysis of laminar activity in normal and injured rat spinal cord by manganese enhanced MRI.
Topics: Animals; Chlorides; Contrast Media; Female; Image Processing, Computer-Assisted; Longitudinal Studie | 2008 |
Manganese enhanced magnetic resonance imaging in a contusion model of spinal cord injury in rats: correlation with motor function.
Topics: Animals; Chlorides; Contrast Media; Disease Models, Animal; Image Enhancement; Image Processing, Com | 2008 |
Maintenance hemodialysis in end-stage renal disease associated with spinal cord injury.
Topics: Acute Kidney Injury; Adult; Aged; Bicarbonates; Blood Pressure; Body Weight; Chlorides; Heart Rate; | 1982 |
Changes in pharmacological sensitivity of the spinal cord to potassium channel blockers following acute spinal cord injury.
Topics: 4-Aminopyridine; Action Potentials; Animals; Axons; Cesium; Chlorides; Electrophysiology; Male; Micr | 1996 |
Superoxide production after spinal injury detected by microperfusion of cytochrome c.
Topics: Animals; Chlorides; Cytochrome c Group; Edetic Acid; Ferric Compounds; Free Radicals; Kinetics; Male | 1998 |
Abnormal axonal physiology is associated with altered expression and distribution of Kv1.1 and Kv1.2 K+ channels after chronic spinal cord injury.
Topics: 4-Aminopyridine; Action Potentials; Animals; Axons; Cesium; Chlorides; Elapid Venoms; Female; Gene E | 2000 |
Cerebrospinal fluid lactate and electrolyte levels following experimental spinal cord injury.
Topics: Animals; Calcium; Cats; Chlorides; Electrolytes; Female; Lactates; Magnesium; Potassium; Sodium; Spi | 1976 |