Page last updated: 2024-10-17

chlorine and Seizures, Febrile

chlorine has been researched along with Seizures, Febrile in 4 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Seizures, Febrile: Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)

Research Excerpts

ExcerptRelevanceReference
"The causes of epilepsies and epileptic seizures are multifactorial."2.46Mutations affecting GABAergic signaling in seizures and epilepsy. ( Galanopoulou, AS, 2010)
"There were 23 patients with convulsions, including 13 with benign convulsions, 9 with febrile seizures, and 1 with epilepsy."1.35Clinical characteristics of benign convulsions with rotavirus gastroenteritis. ( Furukawa, S; Ichiyama, T; Kajimoto, M; Matsushige, T; Motoyama, M; Shiraishi, M, 2009)
"Though children with febrile convulsions only have seizures in the early stage of a febrile illness and not later, these seizures have been attributed to the fever."1.28Hyperpolarization and short-circuiting as mechanisms of seizure prevention following febrile convulsions. ( Aiyathurai, EJ; Jacob, E; Low, PS, 1989)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Puskarjov, M1
Seja, P1
Heron, SE1
Williams, TC1
Ahmad, F1
Iona, X1
Oliver, KL1
Grinton, BE1
Vutskits, L1
Scheffer, IE1
Petrou, S1
Blaesse, P1
Dibbens, LM1
Berkovic, SF1
Kaila, K1
Motoyama, M1
Ichiyama, T1
Matsushige, T1
Kajimoto, M1
Shiraishi, M1
Furukawa, S1
Galanopoulou, AS1
Aiyathurai, EJ1
Low, PS1
Jacob, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Relationship Between Polymorphisms of TRPV1 and KCC2 Gene in Children With Febrile Seizures[NCT04368936]121 participants (Actual)Observational [Patient Registry]2015-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for chlorine and Seizures, Febrile

ArticleYear
Mutations affecting GABAergic signaling in seizures and epilepsy.
    Pflugers Archiv : European journal of physiology, 2010, Volume: 460, Issue:2

    Topics: Angelman Syndrome; Animals; Channelopathies; Chloride Channels; Chlorides; CLC-2 Chloride Channels;

2010

Other Studies

3 other studies available for chlorine and Seizures, Febrile

ArticleYear
A variant of KCC2 from patients with febrile seizures impairs neuronal Cl- extrusion and dendritic spine formation.
    EMBO reports, 2014, Volume: 15, Issue:6

    Topics: Amino Acid Sequence; Animals; Australia; Blotting, Western; Chlorides; Dendritic Spines; Genetic Pre

2014
Clinical characteristics of benign convulsions with rotavirus gastroenteritis.
    Journal of child neurology, 2009, Volume: 24, Issue:5

    Topics: Anticonvulsants; Body Weight; Carbamazepine; Child; Child, Preschool; Chlorides; Creatinine; Female;

2009
Hyperpolarization and short-circuiting as mechanisms of seizure prevention following febrile convulsions.
    Brain & development, 1989, Volume: 11, Issue:4

    Topics: Blood Glucose; Calcium; Cerebral Cortex; Child, Preschool; Chlorides; Electroencephalography; Electr

1989