Page last updated: 2024-10-17

chlorine and Pancreatic Neoplasms

chlorine has been researched along with Pancreatic Neoplasms in 28 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
" Comparisons of cultured pancreatic adenocarcinoma cells expressing the delta 508 mutant CFTR (CFPAC-1 cells) with genetically matched CFPAC-1 cells transfected with the wild-type CFTR demonstrate that expression of wild-type CFTR restores cAMP-mediated plasma membrane Cl- transport, but has no effect on pH regulation of endosomes labeled with either transferrin or wheat germ agglutinin."3.69Regulation of endocytic trafficking and acidification are independent of the cystic fibrosis transmembrane regulator. ( Dunn, KW; Gelman, DL; McGraw, TE; Park, J; Semrad, CE; Shevell, T, 1994)
"Ano1 is also highly expressed in gastrointestinal stromal tumors."1.37Ano1 as a regulator of proliferation. ( Bardsley, MR; Eisenman, ST; Farrugia, G; Gibbons, SJ; Harfe, BD; Ordog, T; Rock, JR; Stanich, JE, 2011)
"Chloride efflux from colon cancer cells is stimulated by cyclic AMP and vaso-active intestinal peptide (VIP), and can be inhibited by pretreatment of the cells with phorbol myristate acetate, which downregulates the cAMP-regulated chloride efflux mechanism."1.29X-ray microanalysis of epithelial and secretory cells in culture. ( Pålsgård, E; Roomans, GM; von Euler, A; von Steyern, CV, 1993)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19906 (21.43)18.7374
1990's15 (53.57)18.2507
2000's3 (10.71)29.6817
2010's3 (10.71)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Shiozaki, A1
Konishi, T1
Kosuga, T1
Kudou, M1
Kurashima, K1
Inoue, H1
Shoda, K1
Arita, T1
Konishi, H1
Morimura, R1
Komatsu, S1
Ikoma, H1
Toma, A1
Kubota, T1
Fujiwara, H1
Okamoto, K1
Otsuji, E1
Sauter, DRP1
Novak, I2
Pedersen, SF1
Larsen, EH1
Hoffmann, EK1
Ignáth, I1
Hegyi, P1
Venglovecz, V1
Székely, CA1
Carr, G1
Hasegawa, M1
Inoue, M1
Takács, T1
Argent, BE1
Gray, MA1
Rakonczay, Z1
Stanich, JE1
Gibbons, SJ1
Eisenman, ST1
Bardsley, MR1
Rock, JR1
Harfe, BD1
Ordog, T1
Farrugia, G1
Tajima, N1
Utano, K1
Kijima, S1
Kawai, A1
Fujita, A1
Sakuma, K1
Sugimoto, H1
Fujii, H1
DUKA, TV1
DESOUSA, RC1
JENNY, M1
Hede, SE1
Hansen, MR1
Dunn, KW1
Park, J1
Semrad, CE1
Gelman, DL1
Shevell, T1
McGraw, TE1
Rosenfeld, MA1
Rosenfeld, SJ1
Danel, C1
Banks, TC1
Crystal, RG1
Pålsgård, E2
Lindh, U1
Juntti-Berggren, L1
Berggren, PO1
Roomans, GM2
Grime, GW1
von Euler, A1
von Steyern, CV1
Platano, D1
Pollo, A1
Carbone, E1
Aicardi, G1
Ravichandran, D1
Cooper, A1
Johnson, CD1
Villanueva, CM1
Kogevinas, M1
Grimalt, JO1
Reissigl, H1
Bodner, E1
Falser, N1
Tahiri-Jouti, N1
Cambillau, C1
Viguerie, N1
Vidal, C1
Buscail, L1
Saint Laurent, N1
Vaysse, N1
Susini, C1
Becq, F1
Fanjul, M1
Mahieu, I1
Berger, Z1
Gola, M1
Hollande, E1
Bradbury, NA2
Jilling, T1
Berta, G1
Sorscher, EJ1
Bridges, RJ1
Kirk, KL1
Eidelman, O1
Guay-Broder, C1
van Galen, PJ1
Jacobson, KA1
Fox, C1
Turner, RJ1
Cabantchik, ZI1
Pollard, HB1
Schoumacher, RA1
Ram, J1
Iannuzzi, MC1
Wallace, RW1
Hon, CT1
Kelly, DR1
Schmid, SM1
Gelder, FB1
Rado, TA1
Kusano, K2
Gainer, H2
Brose, N1
Thomas, A1
Weber, MG1
Jahn, R1
Trebilcock, R1
Lynch, A1
Tomlinson, S1
Best, L1
Stoker, DJ1
Wynn, V1
Sato, T1
Komatsu, K1
Waddell, WR1
Loughry, RW1

Reviews

1 review available for chlorine and Pancreatic Neoplasms

ArticleYear
[Drinking water chlorination and adverse health effects: review of epidemiological studies].
    Medicina clinica, 2001, Jun-09, Volume: 117, Issue:1

    Topics: Chlorides; Colonic Neoplasms; Female; Humans; Male; Pancreatic Neoplasms; Pregnancy; Prenatal Exposu

2001

Other Studies

27 other studies available for chlorine and Pancreatic Neoplasms

ArticleYear
Roles of voltage‑gated potassium channels in the maintenance of pancreatic cancer stem cells.
    International journal of oncology, 2021, Volume: 59, Issue:4

    Topics: 4-Aminopyridine; Aldehyde Dehydrogenase 1 Family; Animals; Chlorides; Female; Humans; Mice; Mice, In

2021
ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC).
    Pflugers Archiv : European journal of physiology, 2015, Volume: 467, Issue:7

    Topics: Adenocarcinoma; Anoctamin-1; Calcium; Case-Control Studies; Cell Line, Tumor; Cell Movement; Chlorid

2015
CFTR expression but not Cl- transport is involved in the stimulatory effect of bile acids on apical Cl-/HCO3- exchange activity in human pancreatic duct cells.
    Pancreas, 2009, Volume: 38, Issue:8

    Topics: Animals; Bicarbonates; Biological Transport; Calcium; Calcium Signaling; Carcinoma, Pancreatic Ducta

2009
Ano1 as a regulator of proliferation.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 301, Issue:6

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Animals, Newborn; Anoctamin-1; Antineopla

2011
Intraductal papillary mucinous neoplasm penetrating to the stomach, duodenum, and jejunum demonstrated on MR cholangiopancreatography with an oral negative contrast agent.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:1

    Topics: Administration, Oral; Aged; Carcinoma, Pancreatic Ductal; Chlorides; Cholangiopancreatography, Magne

2013
[EFFECT OF CHOLINE CHLORIDE ON SOME FUNCTIONS OF THE LIVER IN BOTKIN'S DISEASE].
    Sovetskaia meditsina, 1964, Volume: 27

    Topics: Chlorides; Choline; Communicable Diseases; Drug Therapy; Hepatitis; Hepatitis A; Humans; Liver Funct

1964
[DILUTION HYPONATREMIA IN A CASE OF PANCREATIC CARCINOMA].
    Schweizerische medizinische Wochenschrift, 1964, Jun-27, Volume: 94

    Topics: Blood Chemical Analysis; Body Fluids; Chlorides; Cortisone; Drug Therapy; Ethanol; Geriatrics; Gluco

1964
[DILUTION HYPONATREMIA IN A CASE OF PANCREATIC CARCINOMA].
    Schweizerische medizinische Wochenschrift, 1964, Jun-27, Volume: 94

    Topics: Blood Chemical Analysis; Body Fluids; Chlorides; Cortisone; Drug Therapy; Ethanol; Geriatrics; Gluco

1964
[DILUTION HYPONATREMIA IN A CASE OF PANCREATIC CARCINOMA].
    Schweizerische medizinische Wochenschrift, 1964, Jun-27, Volume: 94

    Topics: Blood Chemical Analysis; Body Fluids; Chlorides; Cortisone; Drug Therapy; Ethanol; Geriatrics; Gluco

1964
[DILUTION HYPONATREMIA IN A CASE OF PANCREATIC CARCINOMA].
    Schweizerische medizinische Wochenschrift, 1964, Jun-27, Volume: 94

    Topics: Blood Chemical Analysis; Body Fluids; Chlorides; Cortisone; Drug Therapy; Ethanol; Geriatrics; Gluco

1964
Adenosine receptors in rat and human pancreatic ducts stimulate chloride transport.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 456, Issue:2

    Topics: Adenocarcinoma; Animals; Calcium Signaling; Cell Line, Tumor; Chloride Channels; Chlorides; Cystic F

2008
Regulation of endocytic trafficking and acidification are independent of the cystic fibrosis transmembrane regulator.
    The Journal of biological chemistry, 1994, Feb-18, Volume: 269, Issue:7

    Topics: Adenocarcinoma; Cell Line; Cell Membrane; Chloride Channels; Chlorides; Colforsin; Cystic Fibrosis T

1994
Increasing expression of the normal human CFTR cDNA in cystic fibrosis epithelial cells results in a progressive increase in the level of CFTR protein expression, but a limit on the level of cAMP-stimulated chloride secretion.
    Human gene therapy, 1994, Volume: 5, Issue:9

    Topics: Adenocarcinoma; Adenoviruses, Human; Animals; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; C

1994
Proton-induced and electron-induced X-ray microanalysis of insulin-secreting cells.
    Scanning microscopy. Supplement, 1994, Volume: 8

    Topics: Animals; Calcium; Cell Line; Chlorides; Electron Probe Microanalysis; Insulin; Insulin Secretion; In

1994
X-ray microanalysis of epithelial and secretory cells in culture.
    Scanning microscopy, 1993, Volume: 7, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Chloride Channels; Chlorides; Colonic Neoplasms; Cyclic AMP; Cysti

1993
Up-regulation of L- and non-L, non-N-type Ca2+ channels by basal and stimulated protein kinase C activation in insulin-secreting RINm5F cells.
    FEBS letters, 1996, Aug-05, Volume: 391, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Barium; Cadmium; Cadmium Chloride; Calcium Channel Blockers; Calciu

1996
Growth inhibitory effect of lithium gammalinolenate on pancreatic cancer cell lines: the influence of albumin and iron.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:1

    Topics: Albumins; Cell Division; Chlorides; Dose-Response Relationship, Drug; Drug Screening Assays, Antitum

1998
[Balanced parenteral nutrition following total pancreatectomy. (Metabolic data)].
    Infusionstherapie und klinische Ernahrung, 1975, Volume: 2, Issue:2

    Topics: Aged; Antibodies; Blood Glucose; Blood Proteins; Calcium; Chlorides; Duodenum; Feces; Female; Humans

1975
Characterization of a membrane tyrosine phosphatase in AR42J cells: regulation by somatostatin.
    The American journal of physiology, 1992, Volume: 262, Issue:6 Pt 1

    Topics: Animals; Cell Line; Cell Membrane; Chlorides; Chromatography, Gel; Enzyme Stability; Hydrogen-Ion Co

1992
Anion channels in a human pancreatic cancer cell line (Capan-1) of ductal origin.
    Pflugers Archiv : European journal of physiology, 1992, Volume: 420, Issue:1

    Topics: Adenocarcinoma; Anions; Cell Membrane; Chloride Channels; Chlorides; Electrochemistry; Humans; Ion C

1992
Regulation of plasma membrane recycling by CFTR.
    Science (New York, N.Y.), 1992, Apr-24, Volume: 256, Issue:5056

    Topics: Base Sequence; Cell Membrane; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Tra

1992
A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Jun-15, Volume: 89, Issue:12

    Topics: 2-Chloroadenosine; Adenocarcinoma; Adenosine; Cell Line; Chlorides; Chromosome Deletion; Colonic Neo

1992
A cystic fibrosis pancreatic adenocarcinoma cell line.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:10

    Topics: Adenocarcinoma; Antigens, Neoplasm; Base Sequence; Cell Division; Cell Line; Chloride Channels; Chlo

1990
Whole cell current analyses of pancreatic acinar AR42J cells. I. Voltage- and Ca(2+)-activated currents.
    The American journal of physiology, 1991, Volume: 260, Issue:5 Pt 1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Calcium; Calcium Channels; Cell

1991
Whole cell current analyses of pancreatic acinar AR42J cells. II. CCK and receptor-activated membrane currents.
    The American journal of physiology, 1991, Volume: 260, Issue:5 Pt 1

    Topics: Animals; Calcimycin; Calcium Channels; Cell Line; Chlorides; Cholecystokinin; Egtazic Acid; Kinetics

1991
A chloride- and calcium-dependent glutamate-binding protein from rat brain. Identification as a ubiquitous constituent of the inner mitochondrial membrane.
    The Journal of biological chemistry, 1990, Jun-25, Volume: 265, Issue:18

    Topics: Animals; Calcium; Cell Line; Cell Membrane; Cerebellum; Cerebral Cortex; Chlorides; Fluorescent Anti

1990
Na+/H+ exchange is responsible for intracellular pH regulation in insulin-secreting HIT-T15 cells.
    Molecular and cellular endocrinology, 1990, May-28, Volume: 71, Issue:1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1990
Pancreatic islet cell tumour with watery diarrhoea and hypokalaemia.
    Gut, 1970, Volume: 11, Issue:11

    Topics: Adenoma, Islet Cell; Bicarbonates; Chlorides; Diarrhea; Feces; Female; Hematocrit; Humans; Hypokalem

1970
Diarrheogenic tumor of the pancreas.
    American journal of surgery, 1973, Volume: 126, Issue:3

    Topics: Adenoma, Islet Cell; Calcium; Chlorides; Diarrhea; Follow-Up Studies; Gastric Juice; Gastrins; Human

1973
Gastric acid secretion after pancreaticoduodenectomy.
    Archives of surgery (Chicago, Ill. : 1960), 1968, Volume: 96, Issue:4

    Topics: Adenoma; Adenoma, Chromophobe; Adult; Aged; Bile Duct Neoplasms; Carcinoma; Chlorides; Common Bile D

1968