chlorine has been researched along with Nerve Pain in 19 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Various neuropathic pain models provide considerable evidence that changes in the glutamatergic, GABAergic, and monoaminergic systems." | 2.53 | The Role of Regulatory Transporters in Neuropathic Pain. ( Kerr, BJ; Yousuf, MS, 2016) |
| "Mechanical allodynia - the misperception of light touch as painful - occurs when inhibition is compromised." | 1.51 | Excitatory neurons are more disinhibited than inhibitory neurons by chloride dysregulation in the spinal dorsal horn. ( Lee, KY; Prescott, SA; Ratté, S, 2019) |
| "The behavioral features of neuropathic pain are not sexually dimorphic despite sex differences in the underlying neuroimmune signaling." | 1.51 | Chloride Dysregulation through Downregulation of KCC2 Mediates Neuropathic Pain in Both Sexes. ( De Koninck, Y; Gauthier, C; Lee, KY; Lorenzo, LE; Mapplebeck, JCS; Muley, MM; Prescott, SA; Salter, MW, 2019) |
| "Using the spared nerve injury model of neuropathic pain in Long-Evans rats, we first discovered a significant increase in noradrenergic innervation within the mPFC of nerve-injured compared to control animals." | 1.48 | Noradrenergic fiber sprouting and altered transduction in neuropathic prefrontal cortex. ( Cordeiro Matos, S; Longo, G; Ribeiro-da-Silva, A; Séguéla, P; Zamfir, M, 2018) |
| "Chronic neuropathic pain is a debilitating condition that remains difficult to treat." | 1.43 | Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain. ( Chen, H; Chen, SR; Hittelman, WN; Li, L; Pan, HL; Wen, L; Xie, JD, 2016) |
| "Although trigeminal neuropathic pain is one of the most common chronic pain syndromes, the etiology is still unknown." | 1.39 | Pre- and post-synaptic switches of GABA actions associated with Cl- homeostatic changes are induced in the spinal nucleus of the trigeminal nerve in a rat model of trigeminal neuropathic pain. ( Fukuda, A; Furukawa, T; Inoue, K; Kumada, T; Sato, K; Watanabe, M; Wei, B, 2013) |
| "The spared nerve injury (SNI) model of neuropathic pain was used for the purposes of this study." | 1.38 | Oral manganese as an MRI contrast agent for the detection of nociceptive activity. ( Behera, D; Biswal, S; Gold, G; Jacobs, KE; Moseley, M; Rosenberg, J; Yeomans, D, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 17 (89.47) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, KY | 2 |
| Ratté, S | 1 |
| Prescott, SA | 2 |
| Lorenzo, LE | 2 |
| Godin, AG | 1 |
| Ferrini, F | 1 |
| Bachand, K | 2 |
| Plasencia-Fernandez, I | 1 |
| Labrecque, S | 1 |
| Girard, AA | 1 |
| Boudreau, D | 2 |
| Kianicka, I | 2 |
| Gagnon, M | 2 |
| Doyon, N | 1 |
| Ribeiro-da-Silva, A | 2 |
| De Koninck, Y | 4 |
| Castro, A | 1 |
| Li, Y | 1 |
| Raver, C | 1 |
| Chandra, R | 1 |
| Masri, R | 1 |
| Lobo, MK | 1 |
| Keller, A | 1 |
| Cordeiro Matos, S | 1 |
| Zamfir, M | 1 |
| Longo, G | 1 |
| Séguéla, P | 1 |
| Tillman, L | 1 |
| Zhang, J | 1 |
| Mapplebeck, JCS | 1 |
| Gauthier, C | 1 |
| Muley, MM | 1 |
| Salter, MW | 3 |
| Bergeron, MJ | 1 |
| Lavertu, G | 1 |
| Castonguay, A | 1 |
| Tripathy, S | 1 |
| Bonin, RP | 1 |
| Perez-Sanchez, J | 1 |
| Wang, B | 1 |
| Dumas, L | 1 |
| Valade, I | 1 |
| Jacob-Wagner, M | 1 |
| Tardif, C | 1 |
| Isenring, P | 1 |
| Attardo, G | 1 |
| Coull, JA | 1 |
| Jeong, KY | 1 |
| Kim, HM | 1 |
| Kang, JH | 1 |
| Yousuf, MS | 1 |
| Kerr, BJ | 1 |
| Li, L | 2 |
| Chen, SR | 2 |
| Chen, H | 2 |
| Wen, L | 1 |
| Hittelman, WN | 1 |
| Xie, JD | 1 |
| Pan, HL | 2 |
| Tominaga, M | 1 |
| Kamaleddin, MA | 1 |
| Kahle, KT | 1 |
| Rinehart, J | 1 |
| Lifton, RP | 1 |
| Beggs, S | 2 |
| Jacobs, KE | 1 |
| Behera, D | 1 |
| Rosenberg, J | 1 |
| Gold, G | 1 |
| Moseley, M | 1 |
| Yeomans, D | 1 |
| Biswal, S | 1 |
| Asiedu, MN | 1 |
| Mejia, G | 1 |
| Ossipov, MK | 1 |
| Malan, TP | 1 |
| Kaila, K | 1 |
| Price, TJ | 1 |
| Zhou, HY | 1 |
| Byun, HS | 1 |
| Han, HD | 1 |
| Lopez-Berestein, G | 1 |
| Sood, AK | 1 |
| Wei, B | 1 |
| Kumada, T | 1 |
| Furukawa, T | 1 |
| Inoue, K | 1 |
| Watanabe, M | 1 |
| Sato, K | 1 |
| Fukuda, A | 1 |
| Keller, AF | 1 |
5 reviews available for chlorine and Nerve Pain
| Article | Year |
|---|---|
Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K
Topics: Central Nervous System; Chloride Channels; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Gene Target | 2019 |
The Role of Regulatory Transporters in Neuropathic Pain.
Topics: Animals; Biogenic Monoamines; Chlorides; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Membrane Tr | 2016 |
[Thermosensitive TRP channels and brain function].
Topics: Animals; Anoctamin-1; Calcium; Calcium Channels; Chloride Channels; Chlorides; Drug Discovery; Human | 2016 |
Molecular, biophysical, and pharmacological properties of calcium-activated chloride channels.
Topics: Animals; Asthma; Calcium; Chloride Channels; Chlorides; Cystic Fibrosis; Humans; Ion Channel Gating; | 2018 |
Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases.
Topics: Anemia, Sickle Cell; Animals; Caenorhabditis; Chlorides; Enzyme Activation; Epilepsy; Humans; Hypert | 2010 |
14 other studies available for chlorine and Nerve Pain
| Article | Year |
|---|---|
Excitatory neurons are more disinhibited than inhibitory neurons by chloride dysregulation in the spinal dorsal horn.
Topics: Animals; Chlorides; Female; Hyperalgesia; K Cl- Cotransporters; Male; Models, Animal; Models, Biolog | 2019 |
Enhancing neuronal chloride extrusion rescues α2/α3 GABA
Topics: Analgesia; Analgesics; Animals; Brain-Derived Neurotrophic Factor; Chlorides; Disease Models, Animal | 2020 |
Neuropathic pain after chronic nerve constriction may not correlate with chloride dysregulation in mouse trigeminal nucleus caudalis neurons.
Topics: Animals; Chlorides; Disease Models, Animal; Female; K Cl- Cotransporters; Male; Mice; Neuralgia; Neu | 2017 |
Noradrenergic fiber sprouting and altered transduction in neuropathic prefrontal cortex.
Topics: Adrenergic Agents; Animals; Barium Compounds; Chlorides; Disease Models, Animal; Dopamine beta-Hydro | 2018 |
Chloride Dysregulation through Downregulation of KCC2 Mediates Neuropathic Pain in Both Sexes.
Topics: Acetazolamide; Animals; Brain-Derived Neurotrophic Factor; Carbonic Anhydrase Inhibitors; Chlorides; | 2019 |
Chloride extrusion enhancers as novel therapeutics for neurological diseases.
Topics: Analgesics; Animals; Chlorides; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; HEK293 Ce | 2013 |
Investigation of the functional difference between the pathological itching and neuropathic pain-induced rat brain using manganese-enhanced MRI.
Topics: Animals; Brain; Chlorides; Contrast Media; Magnetic Resonance Imaging; Male; Manganese Compounds; Ne | 2016 |
Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain.
Topics: Animals; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Homeostasis; Injections, Spinal; K Cl- | 2016 |
Microglia-neuronal signalling in neuropathic pain hypersensitivity 2.0.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Communication; Chlorides; Humans; Microglia; Models | 2010 |
Oral manganese as an MRI contrast agent for the detection of nociceptive activity.
Topics: Administration, Oral; Animals; Chlorides; Contrast Media; Magnetic Resonance Imaging; Male; Manganes | 2012 |
Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice.
Topics: Analgesia; Analgesics; Animals; Benzodiazepines; Chlorides; GABA-A Receptor Agonists; Isoxazoles; K | 2012 |
N-methyl-D-aspartate receptor- and calpain-mediated proteolytic cleavage of K+-Cl- cotransporter-2 impairs spinal chloride homeostasis in neuropathic pain.
Topics: Animals; Biological Transport; Calpain; Chlorides; Electrophysiology; Glutamic Acid; Homeostasis; K | 2012 |
Pre- and post-synaptic switches of GABA actions associated with Cl- homeostatic changes are induced in the spinal nucleus of the trigeminal nerve in a rat model of trigeminal neuropathic pain.
Topics: Animals; Chlorides; Disease Models, Animal; gamma-Aminobutyric Acid; HEK293 Cells; Homeostasis; Huma | 2013 |
Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Cell Communication; Cells, Cultured; Chlorides; | 2007 |