chlorine has been researched along with Nerve Pain in 19 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Excerpt | Relevance | Reference |
---|---|---|
"Various neuropathic pain models provide considerable evidence that changes in the glutamatergic, GABAergic, and monoaminergic systems." | 2.53 | The Role of Regulatory Transporters in Neuropathic Pain. ( Kerr, BJ; Yousuf, MS, 2016) |
"Mechanical allodynia - the misperception of light touch as painful - occurs when inhibition is compromised." | 1.51 | Excitatory neurons are more disinhibited than inhibitory neurons by chloride dysregulation in the spinal dorsal horn. ( Lee, KY; Prescott, SA; Ratté, S, 2019) |
"The behavioral features of neuropathic pain are not sexually dimorphic despite sex differences in the underlying neuroimmune signaling." | 1.51 | Chloride Dysregulation through Downregulation of KCC2 Mediates Neuropathic Pain in Both Sexes. ( De Koninck, Y; Gauthier, C; Lee, KY; Lorenzo, LE; Mapplebeck, JCS; Muley, MM; Prescott, SA; Salter, MW, 2019) |
"Using the spared nerve injury model of neuropathic pain in Long-Evans rats, we first discovered a significant increase in noradrenergic innervation within the mPFC of nerve-injured compared to control animals." | 1.48 | Noradrenergic fiber sprouting and altered transduction in neuropathic prefrontal cortex. ( Cordeiro Matos, S; Longo, G; Ribeiro-da-Silva, A; Séguéla, P; Zamfir, M, 2018) |
"Chronic neuropathic pain is a debilitating condition that remains difficult to treat." | 1.43 | Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain. ( Chen, H; Chen, SR; Hittelman, WN; Li, L; Pan, HL; Wen, L; Xie, JD, 2016) |
"Although trigeminal neuropathic pain is one of the most common chronic pain syndromes, the etiology is still unknown." | 1.39 | Pre- and post-synaptic switches of GABA actions associated with Cl- homeostatic changes are induced in the spinal nucleus of the trigeminal nerve in a rat model of trigeminal neuropathic pain. ( Fukuda, A; Furukawa, T; Inoue, K; Kumada, T; Sato, K; Watanabe, M; Wei, B, 2013) |
"The spared nerve injury (SNI) model of neuropathic pain was used for the purposes of this study." | 1.38 | Oral manganese as an MRI contrast agent for the detection of nociceptive activity. ( Behera, D; Biswal, S; Gold, G; Jacobs, KE; Moseley, M; Rosenberg, J; Yeomans, D, 2012) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (5.26) | 29.6817 |
2010's | 17 (89.47) | 24.3611 |
2020's | 1 (5.26) | 2.80 |
Authors | Studies |
---|---|
Lee, KY | 2 |
Ratté, S | 1 |
Prescott, SA | 2 |
Lorenzo, LE | 2 |
Godin, AG | 1 |
Ferrini, F | 1 |
Bachand, K | 2 |
Plasencia-Fernandez, I | 1 |
Labrecque, S | 1 |
Girard, AA | 1 |
Boudreau, D | 2 |
Kianicka, I | 2 |
Gagnon, M | 2 |
Doyon, N | 1 |
Ribeiro-da-Silva, A | 2 |
De Koninck, Y | 4 |
Castro, A | 1 |
Li, Y | 1 |
Raver, C | 1 |
Chandra, R | 1 |
Masri, R | 1 |
Lobo, MK | 1 |
Keller, A | 1 |
Cordeiro Matos, S | 1 |
Zamfir, M | 1 |
Longo, G | 1 |
Séguéla, P | 1 |
Tillman, L | 1 |
Zhang, J | 1 |
Mapplebeck, JCS | 1 |
Gauthier, C | 1 |
Muley, MM | 1 |
Salter, MW | 3 |
Bergeron, MJ | 1 |
Lavertu, G | 1 |
Castonguay, A | 1 |
Tripathy, S | 1 |
Bonin, RP | 1 |
Perez-Sanchez, J | 1 |
Wang, B | 1 |
Dumas, L | 1 |
Valade, I | 1 |
Jacob-Wagner, M | 1 |
Tardif, C | 1 |
Isenring, P | 1 |
Attardo, G | 1 |
Coull, JA | 1 |
Jeong, KY | 1 |
Kim, HM | 1 |
Kang, JH | 1 |
Yousuf, MS | 1 |
Kerr, BJ | 1 |
Li, L | 2 |
Chen, SR | 2 |
Chen, H | 2 |
Wen, L | 1 |
Hittelman, WN | 1 |
Xie, JD | 1 |
Pan, HL | 2 |
Tominaga, M | 1 |
Kamaleddin, MA | 1 |
Kahle, KT | 1 |
Rinehart, J | 1 |
Lifton, RP | 1 |
Beggs, S | 2 |
Jacobs, KE | 1 |
Behera, D | 1 |
Rosenberg, J | 1 |
Gold, G | 1 |
Moseley, M | 1 |
Yeomans, D | 1 |
Biswal, S | 1 |
Asiedu, MN | 1 |
Mejia, G | 1 |
Ossipov, MK | 1 |
Malan, TP | 1 |
Kaila, K | 1 |
Price, TJ | 1 |
Zhou, HY | 1 |
Byun, HS | 1 |
Han, HD | 1 |
Lopez-Berestein, G | 1 |
Sood, AK | 1 |
Wei, B | 1 |
Kumada, T | 1 |
Furukawa, T | 1 |
Inoue, K | 1 |
Watanabe, M | 1 |
Sato, K | 1 |
Fukuda, A | 1 |
Keller, AF | 1 |
5 reviews available for chlorine and Nerve Pain
Article | Year |
---|---|
Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K
Topics: Central Nervous System; Chloride Channels; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Gene Target | 2019 |
The Role of Regulatory Transporters in Neuropathic Pain.
Topics: Animals; Biogenic Monoamines; Chlorides; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Membrane Tr | 2016 |
[Thermosensitive TRP channels and brain function].
Topics: Animals; Anoctamin-1; Calcium; Calcium Channels; Chloride Channels; Chlorides; Drug Discovery; Human | 2016 |
Molecular, biophysical, and pharmacological properties of calcium-activated chloride channels.
Topics: Animals; Asthma; Calcium; Chloride Channels; Chlorides; Cystic Fibrosis; Humans; Ion Channel Gating; | 2018 |
Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases.
Topics: Anemia, Sickle Cell; Animals; Caenorhabditis; Chlorides; Enzyme Activation; Epilepsy; Humans; Hypert | 2010 |
14 other studies available for chlorine and Nerve Pain
Article | Year |
---|---|
Excitatory neurons are more disinhibited than inhibitory neurons by chloride dysregulation in the spinal dorsal horn.
Topics: Animals; Chlorides; Female; Hyperalgesia; K Cl- Cotransporters; Male; Models, Animal; Models, Biolog | 2019 |
Enhancing neuronal chloride extrusion rescues α2/α3 GABA
Topics: Analgesia; Analgesics; Animals; Brain-Derived Neurotrophic Factor; Chlorides; Disease Models, Animal | 2020 |
Neuropathic pain after chronic nerve constriction may not correlate with chloride dysregulation in mouse trigeminal nucleus caudalis neurons.
Topics: Animals; Chlorides; Disease Models, Animal; Female; K Cl- Cotransporters; Male; Mice; Neuralgia; Neu | 2017 |
Noradrenergic fiber sprouting and altered transduction in neuropathic prefrontal cortex.
Topics: Adrenergic Agents; Animals; Barium Compounds; Chlorides; Disease Models, Animal; Dopamine beta-Hydro | 2018 |
Chloride Dysregulation through Downregulation of KCC2 Mediates Neuropathic Pain in Both Sexes.
Topics: Acetazolamide; Animals; Brain-Derived Neurotrophic Factor; Carbonic Anhydrase Inhibitors; Chlorides; | 2019 |
Chloride extrusion enhancers as novel therapeutics for neurological diseases.
Topics: Analgesics; Animals; Chlorides; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; HEK293 Ce | 2013 |
Investigation of the functional difference between the pathological itching and neuropathic pain-induced rat brain using manganese-enhanced MRI.
Topics: Animals; Brain; Chlorides; Contrast Media; Magnetic Resonance Imaging; Male; Manganese Compounds; Ne | 2016 |
Chloride Homeostasis Critically Regulates Synaptic NMDA Receptor Activity in Neuropathic Pain.
Topics: Animals; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Homeostasis; Injections, Spinal; K Cl- | 2016 |
Microglia-neuronal signalling in neuropathic pain hypersensitivity 2.0.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Communication; Chlorides; Humans; Microglia; Models | 2010 |
Oral manganese as an MRI contrast agent for the detection of nociceptive activity.
Topics: Administration, Oral; Animals; Chlorides; Contrast Media; Magnetic Resonance Imaging; Male; Manganes | 2012 |
Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice.
Topics: Analgesia; Analgesics; Animals; Benzodiazepines; Chlorides; GABA-A Receptor Agonists; Isoxazoles; K | 2012 |
N-methyl-D-aspartate receptor- and calpain-mediated proteolytic cleavage of K+-Cl- cotransporter-2 impairs spinal chloride homeostasis in neuropathic pain.
Topics: Animals; Biological Transport; Calpain; Chlorides; Electrophysiology; Glutamic Acid; Homeostasis; K | 2012 |
Pre- and post-synaptic switches of GABA actions associated with Cl- homeostatic changes are induced in the spinal nucleus of the trigeminal nerve in a rat model of trigeminal neuropathic pain.
Topics: Animals; Chlorides; Disease Models, Animal; gamma-Aminobutyric Acid; HEK293 Cells; Homeostasis; Huma | 2013 |
Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Cell Communication; Cells, Cultured; Chlorides; | 2007 |