chlorine has been researched along with Nerve Degeneration in 43 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Optic neuritis is a common manifestation of multiple sclerosis, an inflammatory demyelinating disease of the CNS." | 5.39 | Calcium influx and calpain activation mediate preclinical retinal neurodegeneration in autoimmune optic neuritis. ( Bahr, BA; Bojcevski, J; Diem, R; Fairless, R; Hoffmann, DB; Müller, A; Naidoo, V; Stadelmann, C; Williams, SK, 2013) |
| "Mn-induced neuron degeneration, astrocytes, and microglia activation contribute to the changes of oxidative stress markers." | 1.42 | Melatonin inhibits manganese-induced motor dysfunction and neuronal loss in mice: involvement of oxidative stress and dopaminergic neurodegeneration. ( Deng, Y; Jiao, C; Li, Y; Liu, W; Mi, C; Wang, F; Xu, B; Xu, Z, 2015) |
| "Optic neuritis is a common manifestation of multiple sclerosis, an inflammatory demyelinating disease of the CNS." | 1.39 | Calcium influx and calpain activation mediate preclinical retinal neurodegeneration in autoimmune optic neuritis. ( Bahr, BA; Bojcevski, J; Diem, R; Fairless, R; Hoffmann, DB; Müller, A; Naidoo, V; Stadelmann, C; Williams, SK, 2013) |
| "Necrosis was evidenced at 4th week of exposure, whereas apoptosis arose at 8th week of exposure." | 1.37 | Toxic effects of inhaled manganese on the olfactory bulb: an ultrastructural approach in mice. ( Colin-Barenque, L; Fortoul, TI; Souza-Gallardo, LM, 2011) |
| "Occurrence of spontaneous epileptic seizures was analyzed at 2 months post-SE using continuous video-EEG monitoring." | 1.35 | Manganese enhanced MRI detects mossy fiber sprouting rather than neurodegeneration, gliosis or seizure-activity in the epileptic rat hippocampus. ( Einula, C; Gröhn, OH; Immonen, RJ; Kharatishvili, I; Pitkänen, A; Sierra, A, 2008) |
| "Although no spontaneous seizures were observed, Kcc3(-/-) mice displayed reduced seizure threshold and spike-wave complexes on electrocorticograms." | 1.32 | Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold. ( Boettger, T; Ehmke, H; Faulhaber, J; Horst, J; Hübner, CA; Jentsch, TJ; Keating, DJ; Lemcke, B; Leuwer, R; Maier, H; Pape, HC; Pfeffer, C; Rust, MB; Scheel, O; Schweizer, M; Seidenbecher, T; Völkl, H, 2003) |
| "Aluminum encephalopathy was formed in rabbits as a result of intraventricular administration of aluminum chloride." | 1.28 | [Pathological changes in the central nervous system studied on the model of aluminum encephalopathy]. ( Butikova, VI; Polonskaia, EL; Zhirov, SV, 1990) |
| " Mice were dosed three times weekly with 300 or 500 mg/kg allyl chloride for periods from 2-17 weeks." | 1.26 | The pathology of allyl chloride neurotoxicity in mice. ( He, F; Jacobs, JM; Scaravilli, F, 1981) |
| "Histopathologic and autoradiographic studies were performed on monkeys of the genera Saimiri and Macaca after acute and chronic oral exposure to several dosage regimens of methylmercuric chloride (MeHg)." | 1.25 | Alkylmercurial encephalopathy in the monkey (Saimiri sciureus and Macaca arctoides): a histopathologic and autoradiographic study. ( Evans, HL; Garman, RH; Weiss, B, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (18.60) | 18.7374 |
| 1990's | 7 (16.28) | 18.2507 |
| 2000's | 14 (32.56) | 29.6817 |
| 2010's | 13 (30.23) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lawes, M | 1 |
| Pinkas, A | 1 |
| Frohlich, BA | 1 |
| Iroegbu, JD | 1 |
| Ijomone, OM | 1 |
| Aschner, M | 3 |
| Olajide, OJ | 1 |
| Asogwa, NT | 1 |
| Moses, BO | 1 |
| Oyegbola, CB | 1 |
| Peres, TV | 1 |
| Arantes, LP | 1 |
| Miah, MR | 1 |
| Bornhorst, J | 1 |
| Schwerdtle, T | 1 |
| Bowman, AB | 1 |
| Leal, RB | 1 |
| Qinli, Z | 1 |
| Meiqing, L | 1 |
| Xia, J | 1 |
| Li, X | 1 |
| Weili, G | 1 |
| Xiuliang, J | 1 |
| Junwei, J | 1 |
| Hailan, Y | 1 |
| Ce, Z | 1 |
| Qiao, N | 1 |
| Hoffmann, DB | 1 |
| Williams, SK | 1 |
| Bojcevski, J | 1 |
| Müller, A | 1 |
| Stadelmann, C | 1 |
| Naidoo, V | 1 |
| Bahr, BA | 1 |
| Diem, R | 1 |
| Fairless, R | 1 |
| Suttkus, A | 1 |
| Rohn, S | 1 |
| Weigel, S | 1 |
| Glöckner, P | 1 |
| Arendt, T | 1 |
| Morawski, M | 1 |
| Deng, Y | 1 |
| Jiao, C | 1 |
| Mi, C | 1 |
| Xu, B | 1 |
| Li, Y | 1 |
| Wang, F | 1 |
| Liu, W | 1 |
| Xu, Z | 1 |
| Ma, X | 1 |
| Han, J | 1 |
| Wu, Q | 1 |
| Liu, H | 1 |
| Shi, S | 1 |
| Wang, C | 1 |
| Wang, Y | 1 |
| Xiao, J | 1 |
| Zhao, J | 2 |
| Jiang, J | 1 |
| Wan, C | 1 |
| Yang, Q | 1 |
| Zhao, C | 1 |
| Ye, Y | 1 |
| Zhao, F | 1 |
| Cai, T | 1 |
| Liu, M | 1 |
| Zheng, G | 1 |
| Luo, W | 1 |
| Chen, J | 1 |
| Zhang, P | 1 |
| Wong, TA | 1 |
| Lokuta, KM | 1 |
| Turner, DE | 1 |
| Vujisic, K | 1 |
| Liu, B | 1 |
| Tong, M | 1 |
| Dong, M | 1 |
| de la Monte, SM | 1 |
| Hershfinkel, M | 1 |
| Kandler, K | 1 |
| Knoch, ME | 1 |
| Dagan-Rabin, M | 1 |
| Aras, MA | 1 |
| Abramovitch-Dahan, C | 1 |
| Sekler, I | 1 |
| Aizenman, E | 1 |
| Milatovic, D | 1 |
| Zaja-Milatovic, S | 1 |
| Gupta, RC | 1 |
| Yu, Y | 1 |
| Colin-Barenque, L | 1 |
| Souza-Gallardo, LM | 1 |
| Fortoul, TI | 1 |
| Peneder, TM | 1 |
| Scholze, P | 1 |
| Berger, ML | 1 |
| Reither, H | 2 |
| Heinze, G | 1 |
| Bertl, J | 1 |
| Bauer, J | 1 |
| Richfield, EK | 1 |
| Hornykiewicz, O | 2 |
| Pifl, C | 2 |
| Haenold, R | 1 |
| Herrmann, KH | 1 |
| Schmidt, S | 1 |
| Reichenbach, JR | 1 |
| Schmidt, KF | 1 |
| Löwel, S | 1 |
| Witte, OW | 1 |
| Weih, F | 1 |
| Kretz, A | 1 |
| Bertrand, A | 1 |
| Khan, U | 1 |
| Hoang, DM | 1 |
| Novikov, DS | 1 |
| Krishnamurthy, P | 1 |
| Rajamohamed Sait, HB | 1 |
| Little, BW | 1 |
| Sigurdsson, EM | 1 |
| Wadghiri, YZ | 1 |
| Boswell, CA | 1 |
| Mundo, EE | 1 |
| Johnstone, B | 1 |
| Ulufatu, S | 1 |
| Schweiger, MG | 1 |
| Bumbaca, D | 1 |
| Fielder, PJ | 1 |
| Prabhu, S | 1 |
| Khawli, LA | 1 |
| Limbrick, DD | 1 |
| Sombati, S | 1 |
| DeLorenzo, RJ | 1 |
| Boettger, T | 1 |
| Rust, MB | 1 |
| Maier, H | 1 |
| Seidenbecher, T | 1 |
| Schweizer, M | 1 |
| Keating, DJ | 1 |
| Faulhaber, J | 1 |
| Ehmke, H | 1 |
| Pfeffer, C | 1 |
| Scheel, O | 1 |
| Lemcke, B | 1 |
| Horst, J | 1 |
| Leuwer, R | 1 |
| Pape, HC | 1 |
| Völkl, H | 1 |
| Hübner, CA | 1 |
| Jentsch, TJ | 1 |
| Khorchide, M | 1 |
| Kattinger, A | 1 |
| Hardy, J | 1 |
| Revuelta, M | 1 |
| Castaño, A | 1 |
| Machado, A | 1 |
| Cano, J | 1 |
| Venero, JL | 1 |
| Lavoie, N | 1 |
| Peralta, MR | 1 |
| Chiasson, M | 1 |
| Lafortune, K | 1 |
| Pellegrini, L | 1 |
| Seress, L | 1 |
| Tóth, K | 1 |
| Immonen, RJ | 1 |
| Kharatishvili, I | 1 |
| Sierra, A | 1 |
| Einula, C | 1 |
| Pitkänen, A | 1 |
| Gröhn, OH | 1 |
| He, F | 1 |
| Jacobs, JM | 1 |
| Scaravilli, F | 1 |
| Lasiter, PS | 1 |
| Glanzman, DL | 1 |
| Maziarz, LJ | 1 |
| Godlewski, A | 1 |
| Goldberg, MP | 1 |
| Choi, DW | 1 |
| Takeda, A | 1 |
| Sawashita, J | 1 |
| Takefuta, S | 1 |
| Okada, S | 1 |
| He, BP | 1 |
| Strong, MJ | 2 |
| Jin, H | 1 |
| Chen, WQ | 1 |
| Tang, XW | 1 |
| Chiang, LY | 1 |
| Yang, CY | 1 |
| Schloss, JV | 1 |
| Wu, JY | 1 |
| Kawahara, M | 1 |
| Kato, M | 1 |
| Kuroda, Y | 1 |
| Garman, RH | 1 |
| Weiss, B | 1 |
| Evans, HL | 1 |
| Peredery, O | 1 |
| Persinger, MA | 1 |
| Blomme, C | 1 |
| Parker, G | 1 |
| Franceschetti, S | 1 |
| Bugiani, O | 1 |
| Panzica, F | 1 |
| Avanzini, G | 1 |
| Lai, JC | 1 |
| Chan, AW | 1 |
| Leung, TK | 1 |
| Minski, MJ | 1 |
| Lim, L | 1 |
| Garruto, RM | 1 |
| Polonskaia, EL | 1 |
| Butikova, VI | 1 |
| Zhirov, SV | 1 |
| Solomon, PR | 2 |
| Pingree, TM | 1 |
| Baldwin, D | 1 |
| Koota, D | 1 |
| Perl, DP | 1 |
| Pendlebury, WW | 2 |
| Beal, MF | 1 |
| Kowall, NW | 1 |
| Crapper, DR | 1 |
| Schlaepfer, WW | 1 |
43 other studies available for chlorine and Nerve Degeneration
| Article | Year |
|---|---|
Metal-induced neurotoxicity in a RAGE-expressing C. elegans model.
Topics: Animals; Animals, Genetically Modified; Cadmium Chloride; Cadmium Poisoning; Caenorhabditis elegans; | 2020 |
Multidirectional inhibition of cortico-hippocampal neurodegeneration by kolaviron treatment in rats.
Topics: Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Animals; Antioxidants; Cell Death; Cerebra | 2017 |
Role of Caenorhabditis elegans AKT-1/2 and SGK-1 in Manganese Toxicity.
Topics: Active Transport, Cell Nucleus; Animals; Animals, Genetically Modified; Behavior, Animal; Caenorhabd | 2018 |
Necrostatin-1 inhibits the degeneration of neural cells induced by aluminum exposure.
Topics: Aluminum Chloride; Aluminum Compounds; Animals; Animals, Newborn; Cell Death; Cell Survival; Cells, | 2013 |
Calcium influx and calpain activation mediate preclinical retinal neurodegeneration in autoimmune optic neuritis.
Topics: Amyloid beta-Protein Precursor; Animals; Calcium; Calpain; Chlorides; Dipeptides; Disease Models, An | 2013 |
Aggrecan, link protein and tenascin-R are essential components of the perineuronal net to protect neurons against iron-induced oxidative stress.
Topics: Aggrecans; Animals; Brain; Brevican; Chlorides; Chondroitin Sulfates; Extracellular Matrix; Extracel | 2014 |
Melatonin inhibits manganese-induced motor dysfunction and neuronal loss in mice: involvement of oxidative stress and dopaminergic neurodegeneration.
Topics: Animals; Antioxidants; Apoptosis; CD11b Antigen; Chlorides; Dopamine; Dopamine Plasma Membrane Trans | 2015 |
Involvement of dysregulated Wip1 in manganese-induced p53 signaling and neuronal apoptosis.
Topics: Animals; Apoptosis; Basal Ganglia; bcl-2-Associated X Protein; bcl-X Protein; Chlorides; Disease Mod | 2015 |
Synthesis and neuroprotective effects of the complex nanoparticles of iron and sapogenin isolated from the defatted seeds of Camellia oleifera.
Topics: Acetylcholine; Animals; Behavior, Animal; Biomarkers; Biphenyl Compounds; Brain; Camellia; Chlorides | 2017 |
Manganese induces dopaminergic neurodegeneration via microglial activation in a rat model of manganism.
Topics: Animals; Chlorides; Dopamine; Gene Expression; Interleukin-1beta; Male; Manganese Compounds; Microgl | 2009 |
Microglia enhance manganese chloride-induced dopaminergic neurodegeneration: role of free radical generation.
Topics: Analysis of Variance; Animals; Animals, Newborn; CD11b Antigen; Cell Survival; Cells, Cultured; Chlo | 2009 |
Brain insulin-like growth factor and neurotrophin resistance in Parkinson's disease and dementia with Lewy bodies: potential role of manganese neurotoxicity.
Topics: Aged; Aged, 80 and over; Animals; Brain; Cells, Cultured; Chlorides; Female; Gene Expression Regulat | 2009 |
Intracellular zinc inhibits KCC2 transporter activity.
Topics: Animals; Cell Line; Cerebral Cortex; Chlorides; Cytoprotection; Humans; Hypoxia-Ischemia, Brain; Int | 2009 |
Oxidative damage and neurodegeneration in manganese-induced neurotoxicity.
Topics: Adenosine Triphosphate; Animals; Basal Ganglia; Biomarkers; Cells, Cultured; Cerebral Cortex; Chlori | 2009 |
Toxic effects of inhaled manganese on the olfactory bulb: an ultrastructural approach in mice.
Topics: Air Pollution; Animals; Chlorides; Inhalation Exposure; Male; Manganese; Manganese Compounds; Mice; | 2011 |
Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice.
Topics: alpha-Synuclein; Animals; Blotting, Western; Chlorides; Chromatography, High Pressure Liquid; Corpus | 2011 |
Magnetic resonance imaging of the mouse visual pathway for in vivo studies of degeneration and regeneration in the CNS.
Topics: Animals; Chlorides; Female; Image Enhancement; Image Processing, Computer-Assisted; Immunohistochemi | 2012 |
Non-invasive, in vivo monitoring of neuronal transport impairment in a mouse model of tauopathy using MEMRI.
Topics: Animals; Chlorides; Contrast Media; Humans; Magnetic Resonance Imaging; Manganese Compounds; Mice; M | 2013 |
Vascular physiology and protein disposition in a preclinical model of neurodegeneration.
Topics: Amyotrophic Lateral Sclerosis; Animals; Blood Volume; Blood-Brain Barrier; Cerebrovascular Circulati | 2013 |
Calcium influx constitutes the ionic basis for the maintenance of glutamate-induced extended neuronal depolarization associated with hippocampal neuronal death.
Topics: Animals; Animals, Newborn; Brain Injuries; Calcium; Calcium Channel Blockers; Calcium Signaling; Cel | 2003 |
Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold.
Topics: Animals; Cell Size; Cerebellum; Chlorides; Deafness; Embryonic and Fetal Development; Gene Deletion; | 2003 |
alpha-Synuclein selectively increases manganese-induced viability loss in SK-N-MC neuroblastoma cells expressing the human dopamine transporter.
Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Cell Death; Cell Line, Tumor; Cell Survival; Chlorides | 2004 |
Kainate-induced zinc translocation from presynaptic terminals causes neuronal and astroglial cell death and mRNA loss of BDNF receptors in the hippocampal formation and amygdala.
Topics: Amygdala; Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Cell Death; Chelating Agents; Chlo | 2005 |
Extracellular chelation of zinc does not affect hippocampal excitability and seizure-induced cell death in rats.
Topics: Animals; Cell Death; Chelating Agents; Chlorides; Edetic Acid; Electrophysiology; Extracellular Spac | 2007 |
Manganese enhanced MRI detects mossy fiber sprouting rather than neurodegeneration, gliosis or seizure-activity in the epileptic rat hippocampus.
Topics: Algorithms; Animals; Blood-Brain Barrier; Chlorides; Chronic Disease; Contrast Media; Data Interpret | 2008 |
The pathology of allyl chloride neurotoxicity in mice.
Topics: Allyl Compounds; Animals; Chlorides; Mice; Nerve Degeneration; Peripheral Nerves; Peripheral Nervous | 1981 |
Cortical substrates of taste aversion learning: dorsal prepiriform (insular) lesions disrupt taste aversion learning.
Topics: Animals; Avoidance Learning; Axons; Brain Mapping; Chlorides; Conditioning, Classical; Lithium; Lith | 1982 |
[Morphological and histoenzymatic changes in the horn of Ammon and cerebellar cortex after administration of large doses of zinc chloride].
Topics: Animals; Cerebellar Cortex; Chlorides; Esterases; Female; Hippocampus; Male; Nerve Degeneration; Rat | 1982 |
Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury.
Topics: Animals; Calcium; Calcium Radioisotopes; Cell Death; Cells, Cultured; Cerebral Cortex; Chlorides; Ex | 1993 |
Distribution of zinc in the substantia nigra of rats treated with 6-hydroxydopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Autoradiography; Blood-Brain Barrier; Ch | 1998 |
A morphological analysis of the motor neuron degeneration and microglial reaction in acute and chronic in vivo aluminum chloride neurotoxicity.
Topics: Aluminum Chloride; Aluminum Compounds; Animals; Axotomy; Brain; Chlorides; Functional Laterality; Mi | 2000 |
Polyhydroxylated C(60), fullerenols, as glutamate receptor antagonists and neuroprotective agents.
Topics: Animals; Binding Sites; Brain; Calcium; Carbon; Cell Death; Cells, Cultured; Chlorides; Excitatory A | 2000 |
Effects of aluminum on the neurotoxicity of primary cultured neurons and on the aggregation of beta-amyloid protein.
Topics: Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Amyloid beta-Peptides; Animals; Astringent | 2001 |
Alkylmercurial encephalopathy in the monkey (Saimiri sciureus and Macaca arctoides): a histopathologic and autoradiographic study.
Topics: Animals; Autoradiography; Brain Diseases; Cerebral Cortex; Chlorides; Ganglia, Spinal; Macaca; Male; | 1975 |
Absence of maternal behavior in rats with lithium/pilocarpine seizure-induced brain damage: support of MacLean's triune brain theory.
Topics: Animals; Brain; Brain Mapping; Cerebral Cortex; Chlorides; Electroencephalography; Evoked Potentials | 1992 |
Synaptic and nonsynaptic determinants of excitability changes in aluminum-intoxicated rabbit CA1 pyramidal neurons studied in vitro.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Culture Techniques; Dose-Respon | 1992 |
Neurochemical changes in rats chronically treated with a high concentration of manganese chloride.
Topics: Acetylcholinesterase; Animals; Brain Diseases; Chlorides; Electrolytes; Manganese; Manganese Compoun | 1992 |
Potentiation in the neurotoxic induction of experimental chronic neurodegenerative disorders: N-butyl benzenesulfonamide and aluminum chloride.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Chronic Disease; Drug Synergism | 1991 |
[Pathological changes in the central nervous system studied on the model of aluminum encephalopathy].
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Brain Diseases; Chlorides; Disease Models, | 1990 |
Disrupted retention of the classically conditioned nictitating membrane response in rabbits with aluminum-induced neurofibrillary degeneration.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Conditioning, Classical; Inject | 1988 |
Results of immunocytochemical, neurochemical, and behavioral studies in aluminum-induced neurofilamentous degeneration.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Behavior, Animal; Brain Chemistry; Chlorid | 1987 |
Experimental neurofibrillary degeneration and altered electrical activity.
Topics: Aluminum; Animals; Brain; Brain Diseases; Cerebral Cortex; Chlorides; Disease Models, Animal; Electr | 1973 |
Calcium-induced degeneration of axoplasm in isolated segments of rat peripheral nerve.
Topics: Animals; Axons; Calcium; Cell Membrane; Cell Membrane Permeability; Chelating Agents; Chlorides; Cyt | 1974 |