chlorine has been researched along with Muscle Spasticity in 8 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Selected examples from three series of isomeric (alkylthio)-1,2,4-triazoles were prepared and examined for anticonvulsant activity versus strychnine-, maximal-electroshock-, pentylenetetrazole-, and 3-mercaptopropionic-acid-induced seizures in mice." | 3.69 | 5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents. ( Dalton, CR; Dudley, MW; Kane, JM; Kehne, JH; Ketteler, HJ; McCloskey, TC; Miller, FP; Ogden, AM; Senyah, Y; Staeger, MA, 1994) |
| "Current anti-spastic medication significantly compromises motor recovery after spinal cord injury (SCI), indicating a critical need for alternative interventions." | 1.91 | Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition with step-training. ( Bilchak, J; Caron, G; Côté, MP, 2023) |
| "At the cellular level, spasticity is considered to be primarily caused by the hyperexcitability of spinal α-motoneurons (MNs) within the spinal stretch reflex circuit." | 1.72 | Molecular Identification of Pro-Excitogenic Receptor and Channel Phenotypes of the Deafferented Lumbar Motoneurons in the Early Phase after SCT in Rats. ( Ji, B; Skup, M; Wojtaś, B, 2022) |
| "Unlike current anti-spastic pharmacological treatments, rehabilitation attenuates spastic symptoms without causing an active depression in spinal excitability, thus avoiding further interference with motor recovery." | 1.56 | Rehabilitation Decreases Spasticity by Restoring Chloride Homeostasis through the Brain-Derived Neurotrophic Factor-KCC2 Pathway after Spinal Cord Injury. ( Beverungen, H; Côté, MP; Klaszky, M; Klaszky, SC, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Ji, B | 1 |
| Wojtaś, B | 1 |
| Skup, M | 1 |
| Caron, G | 1 |
| Bilchak, J | 1 |
| Côté, MP | 2 |
| Beverungen, H | 1 |
| Klaszky, SC | 1 |
| Klaszky, M | 1 |
| Boulenguez, P | 2 |
| Liabeuf, S | 2 |
| Vinay, L | 2 |
| Bos, R | 1 |
| Sadlaoud, K | 1 |
| Buttigieg, D | 1 |
| Brocard, C | 1 |
| Haase, G | 1 |
| Bras, H | 1 |
| Akinfieva, TA | 1 |
| Gerasimova, IL | 1 |
| Kane, JM | 1 |
| Staeger, MA | 1 |
| Dalton, CR | 1 |
| Miller, FP | 1 |
| Dudley, MW | 1 |
| Ogden, AM | 1 |
| Kehne, JH | 1 |
| Ketteler, HJ | 1 |
| McCloskey, TC | 1 |
| Senyah, Y | 1 |
| Matsumoto, K | 1 |
1 review available for chlorine and Muscle Spasticity
| Article | Year |
|---|---|
[Gastric, intestinal and pancreatic diseases and pulmonary findings (including esophageal diseases)].
Topics: Adult; Celiac Disease; Chlorides; Cystic Fibrosis; Esophageal Neoplasms; Female; Gastrointestinal Di | 1971 |
7 other studies available for chlorine and Muscle Spasticity
| Article | Year |
|---|---|
Molecular Identification of Pro-Excitogenic Receptor and Channel Phenotypes of the Deafferented Lumbar Motoneurons in the Early Phase after SCT in Rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chlorides; gamma-Aminobutyric Aci | 2022 |
Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition with step-training.
Topics: Animals; Bumetanide; Chlorides; Motor Neurons; Muscle Spasticity; Rats; Spinal Cord; Spinal Cord Inj | 2023 |
Rehabilitation Decreases Spasticity by Restoring Chloride Homeostasis through the Brain-Derived Neurotrophic Factor-KCC2 Pathway after Spinal Cord Injury.
Topics: Animals; Brain-Derived Neurotrophic Factor; Chlorides; Female; H-Reflex; Homeostasis; K Cl- Cotransp | 2020 |
[Reduced neuronal inhibition and spasticity following spinal cord injury].
Topics: Animals; Brain-Derived Neurotrophic Factor; Chlorides; gamma-Aminobutyric Acid; Glycine; H-Reflex; H | 2011 |
Activation of 5-HT2A receptors upregulates the function of the neuronal K-Cl cotransporter KCC2.
Topics: Animals; Blotting, Western; Bridged Bicyclo Compounds; Chlorides; Gene Expression Regulation; H-Refl | 2013 |
[Comparative toxicity of various barium compounds].
Topics: Animals; Barium; Barium Compounds; Chlorides; Guinea Pigs; Humans; Mice; Muscle Spasticity; Nitrates | 1984 |
5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents.
Topics: Animals; Anticonvulsants; Cerebellum; Cerebral Cortex; Chlorides; Electroshock; Flumazenil; Male; Mi | 1994 |