Page last updated: 2024-10-17

chlorine and Muscle Relaxation

chlorine has been researched along with Muscle Relaxation in 42 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" The rate and amplitude of smooth muscle relaxation at low PO2 were significantly decreased by tolbutamide (5 mmol l-1), which is known to inhibit cyclic AMP-dependent protein kinases."3.68Evidence for decrease in myofilament responsiveness to Ca2+ during hypoxia in spontaneously active vascular smooth muscle in rats. ( Basilyuk, OV; Soloviev, AI, 1993)
"Glycine treatment during tachykinin- and acetylcholine-induced contractions significantly decreased the maintenance of muscle force compared to control."1.37Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle. ( Emala, CW; Gallos, G; Xu, D; Yim, PD; Zhang, Y, 2011)
"Allergic rhinitis, also known as hay fever, rose fever or summer catarrh, is a major challenge to health professionals."1.32Mast cell stabilization, lipoxygenase inhibition, hyaluronidase inhibition, antihistaminic and antispasmodic activities of Aller-7, a novel botanical formulation for allergic rhinitis. ( Amit, A; Bagchi, D; Bagchi, M; D'Souza, P; Pratibha, N; Saxena, VS; Stohs, SJ, 2003)
" The dosage of 230 mg/kg of nicotinamide given intraperitoneally 15 min before STZ administration (65 mg/kg i."1.32Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats. ( Kamata, K; Kobayashi, T; Matsumoto, T; Wakabayashi, K, 2004)
"Furosemide was unable to reduce 86Rb uptake at 10 mM [Cl-], although relaxation was still observed in 10 mM [Cl-]."1.30Furosemide-induced airway relaxation in guinea pigs: relation to Na-K-2Cl cotransporter function. ( Claybaugh, JR; Dressel, MV; Iwamoto, LM; Lavallee, SL; Nakamura, KT; Sato, AK, 1997)
"Indomethacin (1 microM) was found to produce approximately a 100% increase in the cholinergic response."1.29Prejunctional inhibition of cholinergic responses by prostaglandin E2 in human bronchi. ( Conanan, ND; Ellis, JL, 1996)
"Verapamil was found to produce considerable tracheal smooth muscle relaxation from a threshold concentration of 2 X 10(-7) M and with maximum effect at 10(-3) M."1.27The potential bronchodilator action of verapamil. ( Cade, JF; Clegg, EA; Moulds, RF; Pain, MC; Rubinfeld, AR; Santamaria, JD, 1984)
" CaCl2 dose-response (in the presence of 10(-5) mol."1.27Mechanism of hydralazine-induced relaxation of arterial smooth muscle. ( Aloamaka, CP; Ebeigbe, AB, 1985)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19909 (21.43)18.7374
1990's21 (50.00)18.2507
2000's7 (16.67)29.6817
2010's5 (11.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wei, YY1
Sun, LL1
Fu, ST1
Danielsson, J1
Yim, P2
Rinderspacher, A1
Fu, XW1
Zhang, Y3
Landry, DW1
Emala, CW3
Bozarov, A1
Wang, YZ1
Yu, JG1
Wunderlich, J1
Hassanain, HH1
Alhaj, M1
Cooke, HJ1
Grants, I1
Ren, T1
Christofi, FL1
Yim, PD1
Gallos, G2
Xu, D2
Chang, S1
Cook, JM1
Gerthoffer, WT1
Yau, KH1
Mak, JC1
Leung, SW1
Yang, D1
Vanhoutte, PM2
Amit, A1
Saxena, VS1
Pratibha, N1
D'Souza, P1
Bagchi, M1
Bagchi, D1
Stohs, SJ1
Matsumoto, T1
Wakabayashi, K1
Kobayashi, T1
Kamata, K1
Chan, YC1
Yao, XQ1
Lau, CW1
Chan, FL1
He, GW1
Bourreau, JP1
Huang, Y1
Valero, M1
Pereboom, D1
Garay, RP1
Alda, JO1
Sunagane, N1
Fujihara, R1
Uruno, T1
Kubota, K1
Kent, RL1
Harakal, C1
Santamore, WP1
Carey, RA1
Bove, AA1
Cade, JF1
Clegg, EA1
Moulds, RF1
Santamaria, JD1
Rubinfeld, AR1
Pain, MC1
Perez Vallina, JR1
Menendez Antolin, L1
Cantabrana, B1
Sanchez, M1
Hidalgo, A1
Wellman, GC1
Bevan, JA1
Huang, JC1
Garcia, ML1
Reuben, JP1
Kacsorowski, GJ1
Kasten, TP1
Settle, SL1
Misko, TP1
Riley, DP1
Weiss, RH1
Currie, MG1
Nickols, GA1
Greenberg, S1
McGowan, C1
Xie, J1
Summer, WR1
Evora, PR1
Pearson, PJ1
Schaff, HV1
Soloviev, AI1
Basilyuk, OV1
Bowman, JW1
Winterrowd, CA1
Friedman, AR1
Thompson, DP1
Klein, RD1
Davis, JP1
Maule, AG1
Blair, KL1
Geary, TG1
Ellis, JL1
Conanan, ND1
Lavallee, SL1
Iwamoto, LM1
Claybaugh, JR1
Dressel, MV1
Sato, AK1
Nakamura, KT1
Mittra, S1
Singh, M1
Schneider, DA1
Eades, SC1
Sato, T1
Hirota, K1
Matsuki, A1
Zsigmond, EK1
Rabito, SF1
Yarim, M1
Sarac, S1
Ertan, M1
Batu, OS1
Erol, K1
Janssen, LJ1
Wattie, J1
Lu-Chao, H1
Tazzeo, T1
Lu, M1
Battinelli, L1
Daniele, C1
Melchioni, C1
Salvatore, G1
Mazzanti, G1
Raffa, RB1
Aceto, JF1
Goldschmidt, JE1
Tallarida, RJ1
Saha, JK1
Sengupta, JN1
Goyal, RK1
Terai, T1
Deguchi, Y1
Ohtsuka, M1
Kumada, S1
Vaughan, P2
Kootsey, JM1
Feezor, MD1
Kelly, J1
Macdonald, A1
Flavahan, NA1
Robertson, B1
Gebremedhin, D1
Hadházy, P1
Magyar, K1
Rapoport, RM1
Esau, SA1
Sperelakis, N1
Ebeigbe, AB1
Aloamaka, CP1
Byrne, NG1
Muir, TC1

Other Studies

42 other studies available for chlorine and Muscle Relaxation

ArticleYear
HEF-19-induced relaxation of colonic smooth muscles and the underlying mechanisms.
    World journal of gastroenterology, 2013, Aug-28, Volume: 19, Issue:32

    Topics: Acetylcholine; Animals; Barium Compounds; Calcium Channel Blockers; Calcium Channels; Calcium Chlori

2013
Chloride channel blockade relaxes airway smooth muscle and potentiates relaxation by β-agonists.
    American journal of physiology. Lung cellular and molecular physiology, 2014, Aug-01, Volume: 307, Issue:3

    Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Asthma; Cell Membrane; Chloride Channels; Chloride

2014
Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:6

    Topics: Adenosine; Animals; Chlorides; Cimetidine; Colon; Dihydropyridines; Dimaprit; Dose-Response Relation

2009
Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:5

    Topics: Acetylcholine; Animals; Cells, Cultured; Cesium; Chlorides; Electrophysiology; Glycine; Guinea Pigs;

2011
Targeting the restricted α-subunit repertoire of airway smooth muscle GABAA receptors augments airway smooth muscle relaxation.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Jan-15, Volume: 302, Issue:2

    Topics: Animals; Asthma; Benzodiazepines; Cell Line; Chlorides; GABA-A Receptor Agonists; Guinea Pigs; Human

2012
A synthetic chloride channel relaxes airway smooth muscle of the rat.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Anions; Calcimycin; Calcium Ionophores; Carbachol; Chloride Channels; Chlorides; Cystic Fib

2012
Mast cell stabilization, lipoxygenase inhibition, hyaluronidase inhibition, antihistaminic and antispasmodic activities of Aller-7, a novel botanical formulation for allergic rhinitis.
    Drugs under experimental and clinical research, 2003, Volume: 29, Issue:3

    Topics: Animals; Barium Compounds; Carbachol; Cetirizine; Chlorides; Dose-Response Relationship, Drug; Drug

2003
Alterations in vascular endothelial function in the aorta and mesenteric artery in type II diabetic rats.
    Canadian journal of physiology and pharmacology, 2004, Volume: 82, Issue:3

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Chlorides; Diabetes Mellitus, Experimen

2004
The relaxant effect of urocortin in rat pulmonary arteries.
    Regulatory peptides, 2004, Sep-15, Volume: 121, Issue:1-3

    Topics: Animals; Barium Compounds; Carbazoles; Chlorides; Corticotropin-Releasing Hormone; Endothelium; Indo

2004
Role of chloride transport proteins in the vasorelaxant action of nitroprusside in isolated rat aorta.
    European journal of pharmacology, 2006, Dec-28, Volume: 553, Issue:1-3

    Topics: Animals; Aorta, Thoracic; Calcium; Cations; Chloride Channels; Chlorides; Culture Media; Cyclic GMP;

2006
Mechanism of relaxant action of papaverine IV. Roles of sodium ion and cyclic AMP.
    Japanese journal of pharmacology, 1984, Volume: 35, Issue:4

    Topics: Animals; Bucladesine; Chlorides; Colon; Cyclic AMP; Deoxycholic Acid; Guinea Pigs; Lithium; Lithium

1984
An index for comparing the inhibitory action of vasodilators.
    European journal of pharmacology, 1982, Nov-05, Volume: 85, Issue:1

    Topics: Animals; Barium; Barium Compounds; Chlorides; In Vitro Techniques; Male; Muscle Relaxation; Muscle,

1982
The potential bronchodilator action of verapamil.
    The Australian journal of experimental biology and medical science, 1984, Volume: 62 ( Pt 2)

    Topics: Animals; Barium; Barium Compounds; Bronchi; Chlorides; Dinoprost; Dose-Response Relationship, Drug;

1984
Involvement of sodium/calcium exchange in the diclofenac-induced spasmolytic effect on rat uterus.
    General pharmacology, 1995, Volume: 26, Issue:6

    Topics: Amiloride; Animals; Calcium; Chlorides; Diclofenac; Dose-Response Relationship, Drug; Female; Ion Ex

1995
Barium inhibits the endothelium-dependent component of flow but not acetylcholine-induced relaxation in isolated rabbit cerebral arteries.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:1

    Topics: Acetylcholine; Animals; Barium Compounds; Benzopyrans; Cerebral Arteries; Chlorides; Cromakalim; End

1995
Inhibition of beta-adrenoceptor agonist relaxation of airway smooth muscle by Ca(2+)-activated K+ channel blockers.
    European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1

    Topics: Acetylcholine; Albuterol; Animals; Cadmium; Cadmium Chloride; Calcium; Calcium Channels; Charybdotox

1993
Potentiation of nitric oxide-mediated vascular relaxation by SC52608, a superoxide dismutase mimic.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1995, Volume: 208, Issue:2

    Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Blood Pressure; Chlorides; Cyclic GMP; Endothelium

1995
Selective pulmonary and venous smooth muscle relaxation by furosemide: a comparison with morphine.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3

    Topics: Animals; Arteries; Biological Transport; Chlorides; Dogs; Endothelium, Vascular; Female; Furosemide;

1994
Impaired endothelium-dependent relaxation after coronary reperfusion injury: evidence for G-protein dysfunction.
    The Annals of thoracic surgery, 1994, Volume: 57, Issue:6

    Topics: Acetylcholine; Adenosine Diphosphate; Aluminum Chloride; Aluminum Compounds; Animals; Calcimycin; Ca

1994
Evidence for decrease in myofilament responsiveness to Ca2+ during hypoxia in spontaneously active vascular smooth muscle in rats.
    Experimental physiology, 1993, Volume: 78, Issue:3

    Topics: Actin Cytoskeleton; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Calcium; Chlorides; Cy

1993
Nitric oxide mediates the inhibitory effects of SDPNFLRFamide, a nematode FMRFamide-related neuropeptide, in Ascaris suum.
    Journal of neurophysiology, 1995, Volume: 74, Issue:5

    Topics: Amino Acid Sequence; Animals; Ascaris suum; Chlorides; Culture Media; Female; FMRFamide; Helminth Pr

1995
Prejunctional inhibition of cholinergic responses by prostaglandin E2 in human bronchi.
    American journal of respiratory and critical care medicine, 1996, Volume: 154, Issue:1

    Topics: Acetylcholine; Adult; Atropine; Barium Compounds; Bronchi; Charybdotoxin; Chlorides; Cyclooxygenase

1996
Furosemide-induced airway relaxation in guinea pigs: relation to Na-K-2Cl cotransporter function.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Animals; Animals, Newborn; Biological Transport; Bumetanide; Carrier Proteins; Chlorides; Epithelium

1997
Possible mechanism of captopril induced endothelium-dependent relaxation in isolated rabbit aorta.
    Molecular and cellular biochemistry, 1998, Volume: 183, Issue:1-2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Ascorbic Acid; Captopril; Chlorides; Dose-

1998
Antagonist of nitric oxide synthesis inhibits nerve-mediated relaxation of isolated strips of rumen and reticulum.
    Journal of dairy science, 1998, Volume: 81, Issue:10

    Topics: Animals; Barium Compounds; Cattle; Chlorides; Electric Stimulation; Muscarinic Antagonists; Muscle R

1998
The role of the N-methyl-D-aspartic acid receptor in the relaxant effect of ketamine on tracheal smooth muscle.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:6

    Topics: Animals; Bronchodilator Agents; Chlorides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Fe

1998
Synthesis, structural elucidation and pharmacological properties of some 5-acetyl-3,4-dihydro-6-methyl-4-(substituted phenyl)-2(1H) -pyrimidinones.
    Farmaco (Societa chimica italiana : 1989), 1999, Jun-30, Volume: 54, Issue:6

    Topics: Animals; Barium Compounds; Calcium Channel Blockers; Chlorides; Ileum; In Vitro Techniques; Magnetic

1999
Muscarinic excitation-contraction coupling mechanisms in tracheal and bronchial smooth muscles.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 91, Issue:3

    Topics: Animals; Bronchi; Bronchial Hyperreactivity; Calcium; Calcium-Transporting ATPases; Carbachol; Chlor

2001
Muscle relaxing activity of Hyssopus officinalis essential oil on isolated intestinal preparations.
    Planta medica, 2002, Volume: 68, Issue:3

    Topics: Acetylcholine; Animals; Barium Compounds; Bicyclic Monoterpenes; Bridged Bicyclo Compounds; Calcium

2002
The effect of lowered extracellular Na+ concentration on ultraviolet light-induced relaxation of vasoconstricted rabbit isolated thoracic aorta.
    Life sciences, 1992, Volume: 51, Issue:25

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcium; Chlorides; Female; Lithium; Muscle Relaxation; Mus

1992
Role of chloride ions in lower esophageal sphincter tone and relaxation.
    The American journal of physiology, 1992, Volume: 263, Issue:1 Pt 1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1992
Effects of the anticholinergic drug prifinium bromide on urinary bladder contractions in rat in vivo and in guinea-pig in vitro.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:4

    Topics: Animals; Atropine; Barium; Barium Compounds; Butylamines; Calcium Channel Blockers; Chlorides; Elect

1991
Kinetic analysis of chloride conductance in frog skeletal muscle at pH 5.
    Pflugers Archiv : European journal of physiology, 1991, Volume: 419, Issue:5

    Topics: Animals; Chlorides; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Membrane Potentials;

1991
Substitute anions and the chloride conductance of frog muscle: effects of chlorate and bromate on steady-state values and kinetics.
    Pflugers Archiv : European journal of physiology, 1991, Volume: 419, Issue:2

    Topics: Animals; Anions; Bromates; Chlorates; Chlorides; Electric Conductivity; Hydrogen-Ion Concentration;

1991
Relaxant effects of alpha-adrenoceptor agonists in the rat isolated gastric fundus.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; At

1990
Pertussis toxin inhibits endothelium-dependent relaxations evoked by fluoride.
    European journal of pharmacology, 1990, Mar-13, Volume: 178, Issue:1

    Topics: Acetylcholine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Coronary Vessels

1990
Actions of anaesthetics and avermectin on GABAA chloride channels in mammalian dorsal root ganglion neurones.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: Anesthetics; Animals; Cats; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Hydr

1989
Inhibition by quinine of endothelium-dependent relaxation of rabbit aortic strips.
    British journal of pharmacology, 1987, Volume: 92, Issue:4

    Topics: 4-Aminopyridine; Aminopyridines; Animals; Aorta, Thoracic; Barium; Barium Compounds; Calcimycin; Chl

1987
Cyclic guanosine monophosphate inhibition of contraction may be mediated through inhibition of phosphatidylinositol hydrolysis in rat aorta.
    Circulation research, 1986, Volume: 58, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Aorta, Thoracic; Atrial Natriuretic

1986
Effect of low chloride on relaxation in hamster diaphragm muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:1

    Topics: Animals; Chlorides; Cricetinae; Diaphragm; Mesocricetus; Muscle Contraction; Muscle Relaxation; Osmo

1986
Mechanism of hydralazine-induced relaxation of arterial smooth muscle.
    Cardiovascular research, 1985, Volume: 19, Issue:7

    Topics: Animals; Barium; Barium Compounds; Calcium; Calcium Chloride; Chlorides; Dose-Response Relationship,

1985
Mechanisms underlying electrical and mechanical responses of the bovine retractor penis to inhibitory nerve stimulation and to an inhibitory extract.
    British journal of pharmacology, 1985, Volume: 85, Issue:1

    Topics: Animals; Cattle; Cell Membrane; Chlorides; Electric Stimulation; Electrophysiology; In Vitro Techniq

1985