Page last updated: 2024-10-17

chlorine and Leishmaniasis, Cutaneous

chlorine has been researched along with Leishmaniasis, Cutaneous in 6 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Leishmaniasis, Cutaneous: An endemic disease that is characterized by the development of single or multiple localized lesions on exposed areas of skin that typically ulcerate. The disease has been divided into Old and New World forms. Old World leishmaniasis is separated into three distinct types according to epidemiology and clinical manifestations and is caused by species of the L. tropica and L. aethiopica complexes as well as by species of the L. major genus. New World leishmaniasis, also called American leishmaniasis, occurs in South and Central America and is caused by species of the L. mexicana or L. braziliensis complexes.

Research Excerpts

ExcerptRelevanceReference
"Disulfiram has primarily been used to treat alcoholism."1.42Antileishmanial Activity of Disulfiram and Thiuram Disulfide Analogs in an Ex Vivo Model System Is Selectively Enhanced by the Addition of Divalent Metal Ions. ( Melby, PC; Peniche, AG; Renslo, AR; Travi, BL, 2015)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Debus, D1
Genç, S1
Kurz, P1
Holzer, M1
Bauer, K1
Heimke-Brinck, R1
Baier, M1
Sebald, H1
Debus, A1
Bogdan, C4
Stahl, KW4
Molkara, S1
Poursoltani, E1
Maleki, M1
Khamesipour, A1
Salehi, M1
Goyonlo, VM1
Jebran, AF1
Schleicher, U2
Steiner, R1
Wentker, P1
Mahfuz, F1
Stahl, HC2
Amin, FM1
Ahmadi, F1
Sauerborn, R1
Bermejo, JL1
Amirih, ML1
Sakhayee, I1
Peniche, AG1
Renslo, AR1
Melby, PC1
Travi, BL1
Oliveira-Neto, MP1
Martins, VJ1
Mattos, MS1
Pirmez, C1
Brahin, LR1
Benchimol, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 2 Study Electrothermocauterisation of Afghan Patients With Anthroponotic Cutaneous Leishmaniasis With and Without Pharmaceutical Chlorite Listed in the German Drug Codex (DAC N-055)[NCT00947362]Phase 2/Phase 3134 participants (Actual)Interventional2004-08-31Completed
Phase II Open Randomized Clinical & Health Economic Trial Comparing Intralesional Antimony Therapy Versus Wound Care Management in Old World Cutaneous Leishmaniasis Patients in Northern Afghanistan[NCT00996463]Phase 263 participants (Anticipated)Interventional2010-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for chlorine and Leishmaniasis, Cutaneous

ArticleYear
Salvage therapy with Sodium chlorosum (formerly DAC N-055) for cases of refractory lupoid cutaneous leishmaniasis: results from a compassionate use study with 0.09% Sodium chlorosum in amphiphilic basic cream.
    BMC infectious diseases, 2019, Nov-28, Volume: 19, Issue:1

    Topics: Administration, Topical; Adolescent; Adult; Child; Child, Preschool; Chlorides; Drug Resistance; Ery

2019
Rapid healing of cutaneous leishmaniasis by high-frequency electrocauterization and hydrogel wound care with or without DAC N-055: a randomized controlled phase IIa trial in Kabul.
    PLoS neglected tropical diseases, 2014, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Afghanistan; Aged; Child; Child, Preschool; Chlorides; Electrocoagulation; Female

2014
A randomized controlled phase IIb wound healing trial of cutaneous leishmaniasis ulcers with 0.045% pharmaceutical chlorite (DAC N-055) with and without bipolar high frequency electro-cauterization versus intralesional antimony in Afghanistan.
    BMC infectious diseases, 2014, Nov-25, Volume: 14

    Topics: Adult; Afghanistan; Antimony Sodium Gluconate; Antiprotozoal Agents; Bandages; Chlorides; Electrocoa

2014

Other Studies

3 other studies available for chlorine and Leishmaniasis, Cutaneous

ArticleYear
Case Report: Local Treatment of a Leishmania tropica Infection in a Syrian Child with a Novel Filmogenic Preparation of Pharmaceutical Sodium Chlorite (LeiProtect®).
    The American journal of tropical medicine and hygiene, 2022, 01-10, Volume: 106, Issue:3

    Topics: Child; Chlorides; Humans; Leishmania tropica; Leishmaniasis, Cutaneous; Middle Aged; Pharmaceutical

2022
Antileishmanial Activity of Disulfiram and Thiuram Disulfide Analogs in an Ex Vivo Model System Is Selectively Enhanced by the Addition of Divalent Metal Ions.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10

    Topics: Animals; Cations, Divalent; Cell Line; Chlorides; Disulfiram; Dose-Response Relationship, Drug; Drug

2015
South American cutaneous leishmaniasis of the eyelids: report of five cases in Rio de Janeiro State, Brazil.
    Ophthalmology, 2000, Volume: 107, Issue:1

    Topics: Aged; Animals; Antimony; Antiprotozoal Agents; Brazil; Child; Child, Preschool; Chlorides; Eye Infec

2000