chlorine has been researched along with Kidney, Polycystic in 22 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with panduratin A reduced the number of renal cyst colonies corresponding with a decrease in cell proliferation and phosphorylated p70/S6K, a downstream target of mTOR signaling." | 5.72 | Pharmacological Effects of Panduratin A on Renal Cyst Development in In Vitro and In Vivo Models of Polycystic Kidney Disease. ( Chabang, N; Fongsupa, S; Soodvilai, S; Srimai, N; Tonum, K; Torres, JA; Tuchinda, P; Weimbs, T, 2022) |
| "Cyst enlargement in polycystic kidney disease (PKD) involves cAMP-activated proliferation of cyst-lining epithelial cells and transepithelial fluid secretion into the cyst lumen via cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel." | 5.39 | Steviol reduces MDCK Cyst formation and growth by inhibiting CFTR channel activity and promoting proteasome-mediated CFTR degradation. ( Chatsudthipong, L; Chatsudthipong, V; Homvisasevongsa, S; Muanprasat, C; Soodvilai, S; Yuajit, C, 2013) |
| "Isoliquiritigenin (ISLQ) is a plant-derived chalcone that has a wide range of biological activities." | 5.38 | Novel action of the chalcone isoliquiritigenin as a cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor: potential therapy for cholera and polycystic kidney disease. ( Chatsudthipong, V; Chokchaisiri, R; Muanprasat, C; Sirianant, L; Soodvilai, S; Suksamrarn, A, 2012) |
| "In autosomal dominant polycystic kidney disease (ADPKD), the precise steps leading to cyst formation and loss of renal function remain uncertain." | 2.42 | Autosomal dominant polycystic kidney disease: molecular genetics and pathophysiology. ( Germino, GG; Sutters, M, 2003) |
| "Understanding polycystic kidney disease: A systems biology approach." | 2.42 | Lillian Jean Kaplan International Prize for advancement in the understanding of polycystic kidney disease. Understanding polycystic kidney disease: a systems biology approach. ( Grantham, JJ, 2003) |
| "Polycystic kidney disease is a bilateral disorder that affects approximately 200,000-400,000 persons in the United States." | 2.36 | Polycystic kidney disease: a predominance of giant nephrons. ( Grantham, JJ, 1983) |
| "Treatment with panduratin A reduced the number of renal cyst colonies corresponding with a decrease in cell proliferation and phosphorylated p70/S6K, a downstream target of mTOR signaling." | 1.72 | Pharmacological Effects of Panduratin A on Renal Cyst Development in In Vitro and In Vivo Models of Polycystic Kidney Disease. ( Chabang, N; Fongsupa, S; Soodvilai, S; Srimai, N; Tonum, K; Torres, JA; Tuchinda, P; Weimbs, T, 2022) |
| "Polycystic kidney diseases are characterized by numerous bilateral renal cysts that continuously enlarge and, through compression of intact nephrons, lead to a decline in kidney function over time." | 1.40 | Hypoxia-inducible factor-1α causes renal cyst expansion through calcium-activated chloride secretion. ( Buchholz, B; Burzlaff, N; Eckardt, KU; Faria, D; Jantsch, J; Klanke, B; Kroening, S; Kunzelmann, K; Schley, G; Schreiber, R; Willam, C, 2014) |
| "Cyst enlargement in polycystic kidney disease (PKD) involves cAMP-activated proliferation of cyst-lining epithelial cells and transepithelial fluid secretion into the cyst lumen via cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel." | 1.39 | Steviol reduces MDCK Cyst formation and growth by inhibiting CFTR channel activity and promoting proteasome-mediated CFTR degradation. ( Chatsudthipong, L; Chatsudthipong, V; Homvisasevongsa, S; Muanprasat, C; Soodvilai, S; Yuajit, C, 2013) |
| "Isoliquiritigenin (ISLQ) is a plant-derived chalcone that has a wide range of biological activities." | 1.38 | Novel action of the chalcone isoliquiritigenin as a cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor: potential therapy for cholera and polycystic kidney disease. ( Chatsudthipong, V; Chokchaisiri, R; Muanprasat, C; Sirianant, L; Soodvilai, S; Suksamrarn, A, 2012) |
| "Hydrocortisone acetate is known to produce polycystic kidney disease when administered to susceptible animals in the perinatal period." | 1.27 | Effects of lithium chloride and ethacrynic acid on experimental polycystic kidney disease. ( Crocker, JF; McDonald, AT, 1988) |
| "By contrast, distal cysts maintained steep concentration gradients for creatinine and urea." | 1.26 | Macropuncture study of polycystic disease in adult human kidneys. ( Grady, A; Grantham, J; Huseman, R; Welling, D, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Tonum, K | 1 |
| Srimai, N | 1 |
| Chabang, N | 1 |
| Fongsupa, S | 1 |
| Tuchinda, P | 1 |
| Torres, JA | 1 |
| Weimbs, T | 1 |
| Soodvilai, S | 4 |
| Talbi, K | 1 |
| Cabrita, I | 1 |
| Schreiber, R | 2 |
| Kunzelmann, K | 2 |
| Shim, JW | 1 |
| Territo, PR | 1 |
| Simpson, S | 1 |
| Watson, JC | 1 |
| Jiang, L | 1 |
| Riley, AA | 1 |
| McCarthy, B | 1 |
| Persohn, S | 1 |
| Fulkerson, D | 1 |
| Blazer-Yost, BL | 1 |
| Yuajit, C | 1 |
| Homvisasevongsa, S | 1 |
| Chatsudthipong, L | 1 |
| Muanprasat, C | 3 |
| Chatsudthipong, V | 3 |
| Buchholz, B | 1 |
| Schley, G | 1 |
| Faria, D | 1 |
| Kroening, S | 1 |
| Willam, C | 1 |
| Klanke, B | 1 |
| Burzlaff, N | 1 |
| Jantsch, J | 1 |
| Eckardt, KU | 1 |
| Pathomthongtaweechai, N | 1 |
| Wallace, DP | 3 |
| Sirianant, L | 1 |
| Chokchaisiri, R | 1 |
| Suksamrarn, A | 1 |
| Sutters, M | 1 |
| Germino, GG | 1 |
| Grantham, JJ | 5 |
| Cuppage, FE | 1 |
| Huseman, RA | 1 |
| Chapman, A | 1 |
| Huseman, R | 1 |
| Grady, A | 1 |
| Welling, D | 1 |
| Grantham, J | 1 |
| Sullivan, LP | 2 |
| Schwiebert, EM | 1 |
| Braunstein, GM | 1 |
| King, SR | 1 |
| Peti-Peterdi, J | 1 |
| Hanaoka, K | 1 |
| Guggino, WB | 1 |
| Guay-Woodford, LM | 1 |
| Bell, PD | 1 |
| Taylor, AL | 1 |
| Perrone, RD | 1 |
| McLaughlin, ML | 1 |
| Crocker, JF | 1 |
| McDonald, AT | 1 |
| Enia, G | 1 |
| Catalano, C | 1 |
| Zoccali, C | 1 |
| Maggiore, Q | 1 |
| Poon, TF | 1 |
| Ward, MK | 1 |
| Kerr, DN | 1 |
| Giselson, N | 1 |
| Heinegard, D | 1 |
| Holmberg, CG | 1 |
| Lindberg, LG | 1 |
| Lindstedt, E | 1 |
| Lindstedt, G | 1 |
| Schersten, B | 1 |
| Gault, MH | 1 |
| Ferguson, EL | 1 |
| Sidhu, JS | 1 |
| Corbin, RP | 1 |
| Raszeja-Wanic, B | 2 |
| Jasiński, K | 2 |
| Szereszewska, H | 2 |
5 reviews available for chlorine and Kidney, Polycystic
| Article | Year |
|---|---|
Cyclic AMP-mediated cyst expansion.
Topics: Animals; Arginine Vasopressin; Calcium Channel Blockers; Calcium Signaling; Cell Proliferation; Chlo | 2011 |
Autosomal dominant polycystic kidney disease: molecular genetics and pathophysiology.
Topics: Apoptosis; Cell Differentiation; Cell Division; Chlorides; Epithelial Cells; Humans; Membrane Protei | 2003 |
Lillian Jean Kaplan International Prize for advancement in the understanding of polycystic kidney disease. Understanding polycystic kidney disease: a systems biology approach.
Topics: Animals; Body Fluids; Cell Division; Chlorides; Cyclic AMP; Humans; Kidney; Polycystic Kidney Diseas | 2003 |
Polycystic kidney disease: a predominance of giant nephrons.
Topics: Aging; Animals; Basement Membrane; Biological Transport; Body Fluids; Cell Membrane Permeability; Ch | 1983 |
Chloride and fluid secretion in polycystic kidney disease.
Topics: Animals; Body Fluids; Chlorides; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Hu | 1998 |
17 other studies available for chlorine and Kidney, Polycystic
| Article | Year |
|---|---|
Pharmacological Effects of Panduratin A on Renal Cyst Development in In Vitro and In Vivo Models of Polycystic Kidney Disease.
Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Cell Proliferation; Chalcones; Chlorides; Cysti | 2022 |
Gender-Dependent Phenotype in Polycystic Kidney Disease Is Determined by Differential Intracellular Ca
Topics: Animals; Anoctamin-1; Calcium; Calcium Signaling; Cell Proliferation; Chlorides; Dihydrotestosterone | 2021 |
Hydrocephalus in a rat model of Meckel Gruber syndrome with a TMEM67 mutation.
Topics: Animals; Brain; Chlorides; Choroid Plexus; Ciliary Motility Disorders; Encephalocele; Female; Hydroc | 2019 |
Steviol reduces MDCK Cyst formation and growth by inhibiting CFTR channel activity and promoting proteasome-mediated CFTR degradation.
Topics: Animals; Apoptosis; Biological Transport; Cell Line; Cell Proliferation; Chlorides; Cystic Fibrosis | 2013 |
Hypoxia-inducible factor-1α causes renal cyst expansion through calcium-activated chloride secretion.
Topics: Animals; Chloride Channels; Chlorides; Dogs; Female; Gene Expression Regulation; Glucose Transport P | 2014 |
Pranlukast inhibits renal epithelial cyst progression via activation of AMP-activated protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; Cell Proliferation; Cell Survival; Chlorides; Chromones; Col | 2014 |
Novel action of the chalcone isoliquiritigenin as a cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor: potential therapy for cholera and polycystic kidney disease.
Topics: Animals; Antidiarrheals; Cell Line; Chalcones; Chlorides; Cholera; Cholera Toxin; Cystic Fibrosis Tr | 2012 |
Ultrastructure and function of cysts from human adult polycystic kidneys.
Topics: Adult; Chlorides; Creatinine; Humans; Hydrogen-Ion Concentration; Microscopy, Electron; Polycystic K | 1980 |
Macropuncture study of polycystic disease in adult human kidneys.
Topics: Adult; Biopsy, Needle; Blood Urea Nitrogen; Body Fluids; Chlorides; Creatinine; Cysts; Female; Glome | 1980 |
Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Autocrine Communication; Calcium; Cell L | 2002 |
Cyst function in polycystic kidney disease: nongradient cysts.
Topics: Absorption; Acetazolamide; Adult; Amiloride; Biological Transport; Bumetanide; Cell Membrane; Chlori | 1989 |
Effects of lithium chloride and ethacrynic acid on experimental polycystic kidney disease.
Topics: Animals; Biological Transport; Blood; Chlorides; Ethacrynic Acid; Female; Histocytochemistry; Hydroc | 1988 |
Hyperchloraemia: a non-specific finding in chronic renal failure.
Topics: Acid-Base Equilibrium; Bicarbonates; Chlorides; Diabetic Nephropathies; Glomerulonephritis; Humans; | 1985 |
Renal medullary cystic disease or familial juvenile nephronophthisis: a renal tubular disease. Biochemical findings in two siblings.
Topics: Adolescent; Alkaline Phosphatase; Amino Acids; Blood Urea Nitrogen; Calcium; Chlorides; Chronic Kidn | 1970 |
Fluid and electrolyte complications of peritoneal dialysis. Choice of dialysis solutions.
Topics: Acute Kidney Injury; Adult; Alkalosis; Bicarbonates; Blood; Blood Glucose; Blood Pressure; Blood Ure | 1971 |
[Studies on pathogenesis of hyperchloremic acidosis in chronic renal diseases].
Topics: Acidosis; Aged; Chlorides; Female; Glomerulonephritis; Humans; Hydrogen-Ion Concentration; Male; Mid | 1967 |
Investigations on pathogenesis of hyperchloremic acidosis in chronic renal diseases.
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Adult; Aged; Bicarbonates; Chlorides; Chronic Diseas | 1968 |