Page last updated: 2024-10-17

chlorine and Iron Overload

chlorine has been researched along with Iron Overload in 10 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)

Research Excerpts

ExcerptRelevanceReference
"Mercury chloride can cause severe liver injury, which involves multiple mechanisms."5.91Oleanolic acid inhibits mercury chloride induced-liver ferroptosis by regulating ROS/iron overload. ( Chen, J; Li, S; Li, W; Li, X; Liu, C; Ma, X; Ouyang, C; Tang, Y; Zhao, J; Zhou, J, 2023)
"Iron overload is a common pathophysiological state underlying many diseases that has a detrimental influence on cells."5.51Dexmedetomidine Promotes SH-SY5Y Cell Resistance Against Impairment of Iron Overload by Inhibiting NF-κB Pathways. ( Hu, XB; Kang, F; Kang, K; Li, J; Li, WH; Liu, LQ; Shen, YX; Xi, ZY, 2019)
" Moreover, a number of phenotype-associated genes in MDS macrophages exhibited diverse responses to iron overload or iron chelation upon stimulation by ferric chloride or deferoxamine (DFO, an iron chelator)."4.02Characteristics of macrophages from myelodysplastic syndrome microenvironment. ( Wu, Z; Xu, Y; Yang, D; Yang, F; Zhang, X, 2021)
"The protective effects of carvedilol, via its antioxidant effect, may have therapeutic potential in patients with iron overload."3.80Carvedilol protects against iron-induced microparticle generation and apoptosis of endothelial cells. ( Cao, JM; Chan, GC; Chan, S; Chen, MP; Cheung, YF, 2014)
"Mercury chloride can cause severe liver injury, which involves multiple mechanisms."1.91Oleanolic acid inhibits mercury chloride induced-liver ferroptosis by regulating ROS/iron overload. ( Chen, J; Li, S; Li, W; Li, X; Liu, C; Ma, X; Ouyang, C; Tang, Y; Zhao, J; Zhou, J, 2023)
"Iron overload is a common pathophysiological state underlying many diseases that has a detrimental influence on cells."1.51Dexmedetomidine Promotes SH-SY5Y Cell Resistance Against Impairment of Iron Overload by Inhibiting NF-κB Pathways. ( Hu, XB; Kang, F; Kang, K; Li, J; Li, WH; Liu, LQ; Shen, YX; Xi, ZY, 2019)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Yang, F1
Wu, Z1
Yang, D1
Zhang, X2
Xu, Y1
Ouyang, C1
Ma, X1
Zhao, J1
Li, S1
Liu, C1
Tang, Y1
Zhou, J1
Chen, J1
Li, X1
Li, W1
Chen, HJ1
Sugiyama, M1
Shimokawa, F1
Murakami, M1
Hashimoto, O1
Matsui, T1
Funaba, M1
Hu, XB1
Xi, ZY1
Liu, LQ1
Kang, K1
Li, WH1
Shen, YX1
Kang, F1
Li, J1
Lee, DH1
Jang, PS1
Chung, NG1
Cho, B1
Jeong, DC1
Kim, HK1
Chan, S1
Chen, MP1
Cao, JM1
Chan, GC1
Cheung, YF1
Budak, H1
Kocpinar, EF1
Gonul, N1
Ceylan, H1
Erol, HS1
Erdogan, O1
Villarroel, P1
Le Blanc, S1
Arredondo, M1
Clark, PR2
Chua-anusorn, W2
St Pierre, TG2
Fleming, AJ1
Jeffrey, GP1
Olynyk, JK1
Pootrakul, P1
Robins, E1
Lindeman, R1

Trials

1 trial available for chlorine and Iron Overload

ArticleYear
Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance.
    Blood, 2005, Jan-15, Volume: 105, Issue:2

    Topics: Biopsy; Chlorides; Humans; Iron; Iron Overload; Liver; Magnetic Resonance Imaging; Manganese Compoun

2005

Other Studies

9 other studies available for chlorine and Iron Overload

ArticleYear
Characteristics of macrophages from myelodysplastic syndrome microenvironment.
    Experimental cell research, 2021, 11-01, Volume: 408, Issue:1

    Topics: Adult; Aged; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cellular Microenvironment; Chl

2021
Oleanolic acid inhibits mercury chloride induced-liver ferroptosis by regulating ROS/iron overload.
    Ecotoxicology and environmental safety, 2023, Jun-15, Volume: 258

    Topics: Chemical and Drug Induced Liver Injury, Chronic; Chlorides; Ferroptosis; Halogens; Humans; Iron; Iro

2023
Response to iron overload in cultured hepatocytes.
    Scientific reports, 2020, 12-03, Volume: 10, Issue:1

    Topics: Adenylate Kinase; Animals; Cell Survival; Cells, Cultured; Chlorides; Ferric Compounds; Ferroptosis;

2020
Dexmedetomidine Promotes SH-SY5Y Cell Resistance Against Impairment of Iron Overload by Inhibiting NF-κB Pathways.
    Neurochemical research, 2019, Volume: 44, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Cell Line, Tumor; Cell Survival; Chlorides; Dexmedetomidine; D

2019
Deferasirox shows in vitro and in vivo antileukemic effects on murine leukemic cell lines regardless of iron status.
    Experimental hematology, 2013, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoates; Cell Line, Tumor; Chlorides; Crosses, Genetic;

2013
Carvedilol protects against iron-induced microparticle generation and apoptosis of endothelial cells.
    Acta haematologica, 2014, Volume: 132, Issue:2

    Topics: Adrenergic beta-Antagonists; Annexin A5; Apoptosis; Carbazoles; Carvedilol; Caspase 3; Cell-Derived

2014
Stimulation of gene expression and activity of antioxidant related enzyme in Sprague Dawley rat kidney induced by long-term iron toxicity.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2014, Volume: 166

    Topics: Animals; Biomarkers; Chlorides; Dose-Response Relationship, Drug; Enzyme Induction; Ferric Compounds

2014
Interleukin-6 and lipopolysaccharide modulate hepcidin mRNA expression by HepG2 cells.
    Biological trace element research, 2012, Volume: 150, Issue:1-3

    Topics: Absorption; Antimicrobial Cationic Peptides; Biological Transport; Cation Transport Proteins; Chlori

2012
Bi-exponential proton transverse relaxation rate (R2) image analysis using RF field intensity-weighted spin density projection: potential for R2 measurement of iron-loaded liver.
    Magnetic resonance imaging, 2003, Volume: 21, Issue:5

    Topics: Animals; Chlorides; Image Processing, Computer-Assisted; Iron; Iron Overload; Liver; Magnetic Resona

2003