chlorine has been researched along with Hepatolenticular Degeneration in 6 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
Excerpt | Relevance | Reference |
---|---|---|
"The most common Wilson disease (WD) mutations p." | 1.43 | Functional analysis and drug response to zinc and D-penicillamine in stable ATP7B mutant hepatic cell lines. ( Aggarwal, A; Bhatt, M; Chandhok, G; Horvath, J; Schmidt, HH; Zibert, A, 2016) |
"The association of ClC-4 and the Wilson's disease protein (ATP7B) was determined by co-immunoprecipitation." | 1.32 | Involvement of chloride channels in hepatic copper metabolism: ClC-4 promotes copper incorporation into ceruloplasmin. ( Wang, T; Weinman, SA, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (66.67) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chandhok, G | 1 |
Horvath, J | 1 |
Aggarwal, A | 1 |
Bhatt, M | 1 |
Zibert, A | 1 |
Schmidt, HH | 1 |
Wang, T | 1 |
Weinman, SA | 1 |
Walshe, JM | 1 |
Koutenský, J | 1 |
Eybl, V | 1 |
Koutenská, M | 1 |
Sýkora, J | 1 |
Mertl, F | 1 |
Sunderman, FW | 1 |
Nomoto, S | 1 |
Wysocki, K | 1 |
Owczarek, L | 1 |
Górski, S | 1 |
Kurnatowska, A | 1 |
6 other studies available for chlorine and Hepatolenticular Degeneration
Article | Year |
---|---|
Functional analysis and drug response to zinc and D-penicillamine in stable ATP7B mutant hepatic cell lines.
Topics: Adenosine Triphosphatases; Apoptosis; Carcinoma, Hepatocellular; Cation Transport Proteins; Cell Sur | 2016 |
Involvement of chloride channels in hepatic copper metabolism: ClC-4 promotes copper incorporation into ceruloplasmin.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Carcinoma, Hepatocellular; Cation Transpor | 2004 |
Management of penicillamine nephropathy in Wilson's disease: a new chelating agent.
Topics: Adolescent; Chelating Agents; Chlorides; Copper; Ethylenediamines; Hepatolenticular Degeneration; Hu | 1969 |
Influence of sodium diethyldithiocarbamate on the toxicity and distribution of copper in mice.
Topics: Animals; Biotransformation; Bone and Bones; Brain; Chelating Agents; Chlorides; Copper; Digestive Sy | 1971 |
Measurement of human serum ceruloplasmin by its p-phenylenediamine oxidase activity.
Topics: Adult; Aniline Compounds; Animals; Bilirubin; Buffers; Ceruloplasmin; Chlorides; Copper; Female; Hem | 1970 |
Investigations by the use of radioactive copper (64Cu) in chronic liver diseases.
Topics: Adolescent; Adult; Aged; Chlorides; Chronic Disease; Copper; Female; Hepatitis; Hepatolenticular Deg | 1969 |