Page last updated: 2024-10-17

chlorine and HbS Disease

chlorine has been researched along with HbS Disease in 33 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Research Excerpts

ExcerptRelevanceReference
"Three patients had sickle cell anemia, two had sickle cell trait and one had S-C disease."1.26Hyperkalemic hyperchloremic metabolic acidosis in sickle cell hemoglobinopathies. ( Arruda, JA; Batlle, D; Itsarayoungyuen, K; Kurtzman, NA, 1982)
"Severe hyponatremia has been observed in three children with sickle cell disease, and mild hyponatremia was noted during 36% of random hospitalizations for sickle crisis secondary to vasoocclusion or infection."1.26Hyponatremia in sickle cell disease. A renal salt-losing state. ( Finberg, L; Kochen, JA; Radel, EG, 1976)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199011 (33.33)18.7374
1990's17 (51.52)18.2507
2000's1 (3.03)29.6817
2010's4 (12.12)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Han, J1
Zhang, X1
Oderinde, J1
Saraf, SL1
Gowhari, M1
Hassan, J1
Jain, S1
Gordeuk, VR1
Molokie, RE1
Kahle, KT1
Rinehart, J1
Lifton, RP1
Quarmyne, MO1
Risinger, M2
Linkugel, A1
Frazier, A1
Joiner, C1
Pan, D1
Kalfa, TA1
Wang, D1
Crable, S1
Ottlinger, A1
Chandra, S1
Mount, DB1
Hübner, CA1
Franco, RS2
Joiner, CH4
Günther, T1
Bookchin, RM1
Lew, DJ1
Balazs, T1
Ueda, Y1
Lew, VL1
Batlle, D1
Itsarayoungyuen, K1
Arruda, JA1
Kurtzman, NA1
Elisaf, M1
Katopodis, K1
Bouradas, K1
Siamopoulos, KC1
Brugnara, C7
De Franceschi, L2
Beuzard, Y3
Jouault, H1
Adragna, NC1
Lauf, PK2
Thompson, H1
Palascak, M1
Culliford, SJ1
Ellory, JC2
Gibson, JS2
Speake, PF2
Schwartz, RS1
Musto, S1
Fabry, ME4
Nagel, RL4
Vitoux, D2
Su, W1
Shmukler, BE1
Chernova, MN1
Stuart-Tilley, AK1
Alper, SL1
Green, M1
Hall, RJ1
Huntsman, RG1
Lawson, A1
Pearson, TC1
Wheeler, PC1
Radel, EG1
Kochen, JA1
Finberg, L1
Lawrence, C1
Hebbel, RP1
Olivieri, O1
Bachir, D1
Clark, MR1
Rossi, ME1
Gunn, RB1
Fröhlich, O1
Bunn, HF1
Tosteson, DC2
al-Rohil, N1
Jennings, ML1
Van Ha, T1
Dew, A1
Ge, DL1
Canessa, M2
Spalvins, A1
Blumenfeld, N1
Hellerstein, S1
Bunthrarungroj, T1

Reviews

6 reviews available for chlorine and HbS Disease

ArticleYear
Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases.
    Biochimica et biophysica acta, 2010, Volume: 1802, Issue:12

    Topics: Anemia, Sickle Cell; Animals; Caenorhabditis; Chlorides; Enzyme Activation; Epilepsy; Humans; Hypert

2010
Mechanisms, regulation and pathologic significance of Mg2+ efflux from erythrocytes.
    Magnesium research, 2006, Volume: 19, Issue:3

    Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Animals; Antiporters; Chlorides; Choline; Cystic Fibros

2006
Membrane transport of Na and K and cell dehydration in sickle erythrocytes.
    Experientia, 1993, Feb-15, Volume: 49, Issue:2

    Topics: Anemia, Sickle Cell; Biological Transport; Calcium; Chlorides; Erythrocyte Membrane; Erythrocytes, A

1993
[Physiopathology of erythrocyte membrane transport].
    Haematologica, 1991, Volume: 76 Suppl 3

    Topics: Anemia, Sickle Cell; Biological Transport; Biological Transport, Active; Carrier Proteins; Cations;

1991
Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology.
    Blood, 1991, Jan-15, Volume: 77, Issue:2

    Topics: Anemia, Sickle Cell; Cations; Cell Adhesion; Cell Membrane Permeability; Chlorides; Cytoplasm; Cytos

1991
Ion content and transport and the regulation of volume in sickle cells.
    Annals of the New York Academy of Sciences, 1989, Volume: 565

    Topics: Anemia, Sickle Cell; Biological Transport; Calcium; Carrier Proteins; Cell Membrane Permeability; Ch

1989

Other Studies

27 other studies available for chlorine and HbS Disease

ArticleYear
Increased vancomycin dosing requirements in sickle cell disease due to hyperfiltration-dependent and independent pathways.
    Haematologica, 2017, Volume: 102, Issue:8

    Topics: Adult; Anemia, Sickle Cell; Anti-Bacterial Agents; Chlorides; Chromium Compounds; Genotype; Glomerul

2017
Volume regulation and KCl cotransport in reticulocyte populations of sickle and normal red blood cells.
    Blood cells, molecules & diseases, 2011, Aug-15, Volume: 47, Issue:2

    Topics: Anemia, Sickle Cell; Automation, Laboratory; Cell Size; Cellular Senescence; Chlorides; Erythrocyte

2011
K-Cl cotransporter gene expression during human and murine erythroid differentiation.
    The Journal of biological chemistry, 2011, Sep-02, Volume: 286, Issue:35

    Topics: Anemia, Sickle Cell; Animals; Anions; Cell Differentiation; Cell Line, Tumor; Chlorides; Erythrocyte

2011
Dehydration and delayed proton equilibria of red blood cells suspended in isosmotic phosphate buffers. Implications for studies of sickled cells.
    The Journal of laboratory and clinical medicine, 1984, Volume: 104, Issue:6

    Topics: Anemia, Sickle Cell; Bicarbonates; Buffers; Chlorides; Erythrocytes; Hemoglobins; Humans; Hydrogen-I

1984
Hyperkalemic hyperchloremic metabolic acidosis in sickle cell hemoglobinopathies.
    The American journal of medicine, 1982, Volume: 72, Issue:2

    Topics: Acidosis, Renal Tubular; Adult; Aged; Aldosterone; Anemia, Sickle Cell; Chlorides; Glomerular Filtra

1982
Hyperkalemic hyperchloremic metabolic acidosis in a patient with sickle cell beta-thalassemia.
    American journal of hematology, 1995, Volume: 50, Issue:2

    Topics: Acidosis; Anemia, Sickle Cell; beta-Thalassemia; Chlorides; Female; Humans; Hyperkalemia; Middle Age

1995
Modulation of erythrocyte potassium chloride cotransport, potassium content, and density by dietary magnesium intake in transgenic SAD mouse.
    Blood, 1996, Oct-01, Volume: 88, Issue:7

    Topics: Anemia, Sickle Cell; Animals; Biological Transport; Carrier Proteins; Chlorides; Diet; Disease Model

1996
Oxidative activation of K-Cl cotransport by diamide in erythrocytes from humans with red cell disorders, and from several other mammalian species.
    The Journal of membrane biology, 1997, Feb-01, Volume: 155, Issue:3

    Topics: Anemia, Sickle Cell; Animals; Carrier Proteins; Cell Size; Child; Chlorides; Diamide; Erythrocytes;

1997
The formation of transferrin receptor-positive sickle reticulocytes with intermediate density is not determined by fetal hemoglobin content.
    Blood, 1997, Oct-15, Volume: 90, Issue:8

    Topics: Anemia, Sickle Cell; Carrier Proteins; Cell Separation; Chlorides; Fetal Hemoglobin; Flow Cytometry;

1997
Effects of urea and oxygen tension on K flux in sickle cells.
    Pflugers Archiv : European journal of physiology, 1998, Volume: 435, Issue:5

    Topics: Anemia, Sickle Cell; Chlorides; Erythrocytes; Hemoglobin, Sickle; Humans; In Vitro Techniques; Ion T

1998
K+-Cl- cotransport: 'to be or not to be' oxygen sensitive.
    The Journal of physiology, 1998, Aug-15, Volume: 511 ( Pt 1)

    Topics: Anemia, Sickle Cell; Carrier Proteins; Chlorides; Erythrocytes; Hemoglobin, Sickle; Humans; Hyperton

1998
Differential oxygen sensitivity of the K+-Cl- cotransporter in normal and sickle human red blood cells.
    The Journal of physiology, 1998, Aug-15, Volume: 511 ( Pt 1)

    Topics: Anemia, Sickle Cell; Bumetanide; Carboxylic Acids; Carrier Proteins; Chlorides; Egtazic Acid; Enzyme

1998
Two distinct pathways mediate the formation of intermediate density cells and hyperdense cells from normal density sickle red blood cells.
    Blood, 1998, Dec-15, Volume: 92, Issue:12

    Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Buffers; Calcium; Carbon Dioxide; Carrier Proteins; Cen

1998
The effect of hemoglobin A and S on the volume- and pH-dependence of K-Cl cotransport in human erythrocyte ghosts.
    The Journal of membrane biology, 1999, Feb-01, Volume: 167, Issue:3

    Topics: Anemia, Sickle Cell; Carrier Proteins; Cell Size; Centrifugation, Density Gradient; Chlorides; Eryth

1999
Mouse K-Cl cotransporter KCC1: cloning, mapping, pathological expression, and functional regulation.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: 3' Untranslated Regions; 5' Untranslated Regions; Amino Acid Sequence; Anemia, Sickle Cell; Animals;

1999
Sickle cell crisis treated by exchange transfusion. Treatment of two patients with heterozygous sickle cell syndrome.
    JAMA, 1975, Mar-03, Volume: 231, Issue:9

    Topics: Adult; Anemia, Sickle Cell; Bicarbonates; Calcium; Chlorides; Exchange Transfusion, Whole Blood; Fev

1975
Hyponatremia in sickle cell disease. A renal salt-losing state.
    The Journal of pediatrics, 1976, Volume: 88, Issue:5

    Topics: Adolescent; Anemia, Sickle Cell; Body Weight; Child; Child, Preschool; Chlorides; Female; Humans; Hy

1976
The unique red cell heterogeneity of SC disease: crystal formation, dense reticulocytes, and unusual morphology.
    Blood, 1991, Oct-15, Volume: 78, Issue:8

    Topics: Anemia, Sickle Cell; Blood Cell Count; Cell Separation; Chlorides; Crystallization; Erythrocytes; Fe

1991
K+ efflux in deoxygenated sickle cells in the presence or absence of DIOA, a specific inhibitor of the [K+, Cl-] cotransport system.
    British journal of haematology, 1991, Volume: 77, Issue:1

    Topics: Adult; Anemia, Sickle Cell; Biological Transport; Carboxylic Acids; Carrier Proteins; Chlorides; Hum

1991
Permeability characteristics of deoxygenated sickle cells.
    Blood, 1990, Nov-15, Volume: 76, Issue:10

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1990
Anion transport in sickle red blood cells.
    Pediatric research, 1990, Volume: 28, Issue:6

    Topics: Anemia, Sickle Cell; Anion Exchange Protein 1, Erythrocyte; Biological Transport, Active; Cell Membr

1990
Volume-dependent K+ transport in rabbit red blood cells comparison with oxygenated human SS cells.
    The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 1

    Topics: Anemia, Sickle Cell; Animals; Anions; Biological Transport; Chlorides; Disease Models, Animal; Eryth

1989
Acid pH induces formation of dense cells in sickle erythrocytes.
    Blood, 1989, Volume: 74, Issue:1

    Topics: Anemia, Sickle Cell; Biological Transport; Centrifugation, Density Gradient; Chlorides; Erythrocytes

1989
Deoxygenation-induced cation fluxes in sickle cells: relationship between net potassium efflux and net sodium influx.
    Blood cells, 1988, Volume: 13, Issue:3

    Topics: Anemia, Sickle Cell; Cations, Monovalent; Cell Separation; Chlorides; Erythrocytes; Humans; Hydrogen

1988
Activation of a K:C1 cotransporter by cell swelling in HbAA and HbSS red cells.
    Progress in clinical and biological research, 1987, Volume: 240

    Topics: Anemia, Sickle Cell; Cell Membrane Permeability; Chlorides; Erythrocyte Aging; Erythrocyte Membrane;

1987
Deoxygenation inhibits the volume-stimulated, Cl(-)-dependent K+ efflux in SS and young AA cells: a cytosolic Mg2+ modulation.
    Blood, 1987, Volume: 70, Issue:6

    Topics: Anemia, Sickle Cell; Chlorides; Cytoplasm; Erythrocyte Aging; Erythrocytes, Abnormal; Hemoglobin A;

1987
Erythrocyte composition in sickle-cell anemia.
    The Journal of laboratory and clinical medicine, 1974, Volume: 83, Issue:4

    Topics: Adolescent; Anemia, Sickle Cell; Child; Child, Preschool; Chlorides; Electrolytes; Electrophoresis;

1974