Page last updated: 2024-10-17

chlorine and Glioma

chlorine has been researched along with Glioma in 42 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"The transport of radiolabeled L-glutamic acid by LRM55 glioma cells in culture was examined."7.67Characterization of L-glutamic acid transport by glioma cells in culture: evidence for sodium-independent, chloride-dependent high affinity influx. ( Martin, DL; Waniewski, RA, 1984)
"Swelling of C6 glioma cells in hypotonic medium (180 mOsm) results in two- to three-fold activation of K+ (86Rb+) influx suppressed by 10 microM bumetanide."3.69Swelling-induced activation of Na+,K+,2Cl- cotransport in C6 glioma cells: kinetic properties and intracellular signalling mechanisms. ( Aksentsev, SL; Fedulov, AS; Konev, SV; Kvacheva, ZB; Mezen, NI; Mongin, AA; Orlov, SN, 1996)
"C6 glioma cells accumulate the organic osmolyte inositol in response to chronic hypertonic stress."3.68Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux. ( Jackson, PS; Strange, K, 1993)
"The transport of radiolabeled L-glutamic acid by LRM55 glioma cells in culture was examined."3.67Characterization of L-glutamic acid transport by glioma cells in culture: evidence for sodium-independent, chloride-dependent high affinity influx. ( Martin, DL; Waniewski, RA, 1984)
"Glioma is a lethal malignant brain cancer, and many reports have shown that abnormalities in the behavior of water and ion channels play an important role in regulating tumor proliferation, migration, apoptosis, and differentiation."1.62Prediction of LncRNA-encoded small peptides in glioma and oligomer channel functional analysis using in silico approaches. ( Cao, Y; Lee, I; Meng, X; Sun, J; Wang, W; Yang, R; Zhang, W, 2021)
"Brain gliomas are highly epileptogenic."1.40Cortical GABAergic excitation contributes to epileptic activities around human glioma. ( Baulac, M; Bielle, F; Capelle, L; Chazal, G; Cresto, N; Devaux, B; Duyckaerts, C; Huberfeld, G; Kourdougli, N; Le Van Quyen, M; Miles, R; Pallud, J; Pellegrino, C; Rivera, C; Varlet, P, 2014)
"Malignant gliomas are highly invasive brain cancers that carry a dismal prognosis."1.39Calcium entry via TRPC1 channels activates chloride currents in human glioma cells. ( Cuddapah, VA; Sontheimer, H; Turner, KL, 2013)
"High-grade gliomas are devastating brain tumors associated with a mean survival of <50 weeks."1.33High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model. ( Bajenaru, ML; Bock, NA; Clarke, L; Guha, A; Gutmann, DH; Henkelman, RM; Herlyn, D; Kaplan, D; Karim, Z; Lavoie, JF; Purev, E; Qian, B; Reti, R; Sabha, N; Scheidenhelm, DK; Shannon, P; Swoboda, R; Tong, A; Wei, Q, 2006)
"This implies that gliomas are dependent upon dynamic HCO(-)(3)-independent H(+) buffering pathways such as the type 1 Na(+)/H(+) exchanger (NHE1)."1.31Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes. ( Cala, PM; Gorin, FA; Jorgensen, NK; McLean, LA; Roscoe, J, 2000)
"The present findings demonstrate that brain tumors can be imaged with radioactive zinc."1.31Zinc-65 imaging of rat brain tumors. ( Enomoto, S; Oku, N; Takeda, A; Tamano, H, 2001)
" Since lithium requires chronic administration for therapeutic efficacy, and because its beneficial effects last well beyond its discontinuation, it has been postulated that lithium may exert major effects at the genomic level."1.30Lithium stimulates gene expression through the AP-1 transcription factor pathway. ( Chen, G; Huang, LD; Manji, HK; Yuan, PX, 1998)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199010 (23.81)18.7374
1990's11 (26.19)18.2507
2000's12 (28.57)29.6817
2010's7 (16.67)24.3611
2020's2 (4.76)2.80

Authors

AuthorsStudies
Cao, Y1
Yang, R1
Lee, I1
Zhang, W1
Sun, J1
Meng, X1
Wang, W1
Stepanenko, AA1
Sosnovtseva, AO1
Valikhov, MP1
Chekhonin, VP1
Wang, Y1
Zhang, S1
Li, SJ1
Pallud, J1
Le Van Quyen, M1
Bielle, F1
Pellegrino, C1
Varlet, P1
Cresto, N1
Baulac, M1
Duyckaerts, C1
Kourdougli, N1
Chazal, G1
Devaux, B1
Rivera, C1
Miles, R1
Capelle, L1
Huberfeld, G1
Di Angelantonio, S1
Murana, E1
Cocco, S1
Scala, F1
Bertollini, C1
Molinari, MG1
Lauro, C1
Bregestovski, P1
Limatola, C1
Ragozzino, D1
Habela, CW3
Olsen, ML2
Sontheimer, H6
Rouzaire-Dubois, B1
Ouanounou, G1
O'Regan, S1
Dubois, JM1
Cuddapah, VA3
Venkatpurwar, V1
Shiras, A1
Pokharkar, V1
Watkins, S1
Moore, LS1
Barclay, TT1
Turner, KL1
Cai, Z1
Song, F1
Yang, MS1
Schade, S1
Lyons, SA1
Amaral, MD1
Toimela, T1
Mäenpää, H1
Mannerström, M1
Tähti, H1
Tauro, JR1
Gemeinhart, RA1
Wei, Q1
Clarke, L1
Scheidenhelm, DK1
Qian, B1
Tong, A1
Sabha, N1
Karim, Z1
Bock, NA1
Reti, R1
Swoboda, R1
Purev, E1
Lavoie, JF1
Bajenaru, ML1
Shannon, P1
Herlyn, D1
Kaplan, D1
Henkelman, RM1
Gutmann, DH1
Guha, A1
Ernest, NJ1
Waniewski, RA1
Martin, DL3
Wolpaw, EW2
Nederman, T1
Acker, H1
Carlsson, J1
Pinegin, LE1
Dolzhenko, DA1
Kato, K1
Hasegawa, K1
Goto, S1
Inaguma, Y1
Jackson, PS1
Strange, K3
McManus, ML1
Mountian, I1
Chou, KY1
Van Driessche, W1
Mongin, AA1
Aksentsev, SL1
Orlov, SN1
Kvacheva, ZB1
Mezen, NI1
Fedulov, AS1
Konev, SV1
Emma, F1
McManus, M1
Kaiho, H1
Matsuoka, I1
Kimura, J1
Nakanishi, H1
Yuan, PX1
Chen, G1
Huang, LD1
Manji, HK1
Pancrazio, JJ1
Ma, W1
Grant, GM1
Shaffer, KM1
Kao, WY1
Liu, QY1
Manos, P1
Barker, JL1
Stenger, DA1
Amoroso, S1
Tortiglione, A1
Secondo, A1
Catalano, A1
Montagnani, S1
Di Renzo, G1
Annunziato, L1
McLean, LA1
Roscoe, J1
Jorgensen, NK1
Gorin, FA1
Cala, PM1
Ringel, F1
Chang, RC1
Staub, F1
Baethmann, A1
Plesnila, N1
Takeda, A1
Tamano, H1
Enomoto, S1
Oku, N1
Manor, D1
Moran, N1
Segal, M1
Perlman, JH1
Gershengorn, MC1
Zafra, F1
Giménez, C1
Chassande, O1
Frelin, C1
Farahifar, D1
Jean, T1
Lazdunski, M1
Shenkin, HA1
Gutterman, P1
Hankiewicz, J1
Lesniak, M1
Miyazaki, Y1
Suematsu, K1
Nakamura, J1

Other Studies

42 other studies available for chlorine and Glioma

ArticleYear
Prediction of LncRNA-encoded small peptides in glioma and oligomer channel functional analysis using in silico approaches.
    PloS one, 2021, Volume: 16, Issue:3

    Topics: Brain Neoplasms; Cell Membrane; Chlorides; Datasets as Topic; Gene Expression Regulation, Neoplastic

2021
A new insight into aggregation of oncolytic adenovirus Ad5-delta-24-RGD during CsCl gradient ultracentrifugation.
    Scientific reports, 2021, 08-09, Volume: 11, Issue:1

    Topics: A549 Cells; Adenoviridae; Adenoviridae Infections; Animals; Antioxidants; Cell Line; Cell Line, Tumo

2021
Zn(2+) induces apoptosis in human highly metastatic SHG-44 glioma cells, through inhibiting activity of the voltage-gated proton channel Hv1.
    Biochemical and biophysical research communications, 2013, Aug-23, Volume: 438, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chlorid

2013
Cortical GABAergic excitation contributes to epileptic activities around human glioma.
    Science translational medicine, 2014, Jul-09, Volume: 6, Issue:244

    Topics: Action Potentials; Brain Neoplasms; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Glioma; Glutamates

2014
A role for intracellular zinc in glioma alteration of neuronal chloride equilibrium.
    Cell death & disease, 2014, Oct-30, Volume: 5

    Topics: Animals; Brain Neoplasms; Chlorides; Coculture Techniques; Female; gamma-Aminobutyric Acid; Glioma;

2014
ClC3 is a critical regulator of the cell cycle in normal and malignant glial cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-10, Volume: 28, Issue:37

    Topics: Analysis of Variance; Angiogenesis Inhibitors; Animals; Animals, Newborn; Cell Cycle; Cell Division;

2008
Sodium-dependent activity of aquaporin-1 in rat glioma cells: a new mechanism of cell volume regulation.
    Pflugers Archiv : European journal of physiology, 2009, Volume: 457, Issue:5

    Topics: Animals; Aquaporin 1; Cell Size; Chlorides; Glioma; Hypotonic Solutions; Ion Channels; Isotonic Solu

2009
Molecular interaction and functional regulation of ClC-3 by Ca2+/calmodulin-dependent protein kinase II (CaMKII) in human malignant glioma.
    The Journal of biological chemistry, 2010, Apr-09, Volume: 285, Issue:15

    Topics: Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Chloride Chan

2010
Porphyran capped gold nanoparticles as a novel carrier for delivery of anticancer drug: in vitro cytotoxicity study.
    International journal of pharmaceutics, 2011, May-16, Volume: 409, Issue:1-2

    Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Chlorides; Doxorubicin; Drug Carriers; Drug Delivery

2011
Kinase activation of ClC-3 accelerates cytoplasmic condensation during mitotic cell rounding.
    American journal of physiology. Cell physiology, 2012, Feb-01, Volume: 302, Issue:3

    Topics: Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Cycle; Cell Division; Cell Line, Tumor; Cel

2012
Calcium entry via TRPC1 channels activates chloride currents in human glioma cells.
    Cell calcium, 2013, Volume: 53, Issue:3

    Topics: Calcium; Chloride Channels; Chlorides; Electric Conductivity; Glioma; Humans; TRPC Cation Channels

2013
Capillary liquid chromatographic-high-resolution mass spectrometric analysis of ribonucleotides.
    Journal of chromatography. A, 2002, Nov-08, Volume: 976, Issue:1-2

    Topics: Cell Extracts; Chlorides; Chromatography, High Pressure Liquid; Glioma; Hydrogen-Ion Concentration;

2002
Expression of voltage-gated chloride channels in human glioma cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jul-02, Volume: 23, Issue:13

    Topics: Antibodies; Astrocytoma; Biopsy; Blotting, Western; Cell Membrane; Chloride Channels; Chlorides; CLC

2003
Development of an in vitro blood-brain barrier model-cytotoxicity of mercury and aluminum.
    Toxicology and applied pharmacology, 2004, Feb-15, Volume: 195, Issue:1

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Blood-Brain Barrier; Cell Line; Cell Line, Tumor; Ce

2004
Development of amine-containing polymeric particles.
    Journal of biomaterials science. Polymer edition, 2005, Volume: 16, Issue:10

    Topics: Amines; Biocompatible Materials; Cell Line, Tumor; Chlorides; Drug Delivery Systems; Fluoresceins; F

2005
High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model.
    Cancer research, 2006, Aug-01, Volume: 66, Issue:15

    Topics: Animals; Brain Neoplasms; Chlorides; Contrast Media; Disease Models, Animal; ErbB Receptors; Gene Ex

2006
Cytoplasmic condensation is both necessary and sufficient to induce apoptotic cell death.
    Journal of cell science, 2008, Feb-01, Volume: 121, Issue:Pt 3

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Apoptosis; Caspases; Cell Death; Cell Line, Tumor;

2008
Characterization of L-glutamic acid transport by glioma cells in culture: evidence for sodium-independent, chloride-dependent high affinity influx.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1984, Volume: 4, Issue:9

    Topics: Animals; Biological Transport; Cells, Cultured; Chlorides; Glioma; Glutamates; Glutamic Acid; Gramic

1984
Cl- transport in a glioma cell line: evidence for two transport mechanisms.
    Brain research, 1984, Apr-16, Volume: 297, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Astrocytes; Bicarbonates; Cell

1984
Penetration of substances into tumor tissue: a methodological study with microelectrodes and cellular spheroids.
    In vitro, 1983, Volume: 19, Issue:6

    Topics: Biological Transport; Calcium; Cations; Cell Aggregation; Cells, Cultured; Chlorides; Cytological Te

1983
[Effect of furosemide on intracranial pressure in patients with intracranial hypertension].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1983, Volume: 83, Issue:5

    Topics: Brain Diseases; Brain Neoplasms; Chlorides; Diuresis; Furosemide; Glioma; Humans; Intracranial Press

1983
Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27.
    The Journal of biological chemistry, 1994, Apr-15, Volume: 269, Issue:15

    Topics: Arsenates; Cadmium; Cadmium Chloride; Cell Line; Centrifugation, Density Gradient; Chlorides; Choler

1994
Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1

    Topics: Animals; Biological Transport; Cell Line; Chloride Channels; Chlorides; Fatty Acids, Nonesterified;

1993
Acute volume regulation of brain cells in response to hypertonic challenge.
    Anesthesiology, 1993, Volume: 78, Issue:6

    Topics: Animals; Brain Neoplasms; Bumetanide; Cell Size; Chlorides; Glioma; Hypertonic Solutions; In Vitro T

1993
Electrolyte transport mechanisms involved in regulatory volume increase in C6 glioma cells.
    The American journal of physiology, 1996, Volume: 271, Issue:4 Pt 1

    Topics: Animals; Antiporters; Bicarbonates; Biological Transport, Active; Carrier Proteins; Cell Size; Chlor

1996
Swelling-induced activation of Na+,K+,2Cl- cotransport in C6 glioma cells: kinetic properties and intracellular signalling mechanisms.
    Biochimica et biophysica acta, 1996, Dec-04, Volume: 1285, Issue:2

    Topics: Bumetanide; Carrier Proteins; Cell Size; Chlorides; Diuretics; Glioma; Hypotonic Solutions; Ion Exch

1996
Intracellular electrolytes regulate the volume set point of the organic osmolyte/anion channel VSOAC.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: Animals; Chlorides; Glioma; Homeostasis; Hypertonic Solutions; Hypotonic Solutions; Intracellular Fl

1997
Identification of P2X7 (P2Z) receptor in N18TG-2 cells and NG108-15 cells.
    Journal of neurochemistry, 1998, Volume: 70, Issue:3

    Topics: Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Cations; Chlorides; Dose-Resp

1998
Lithium stimulates gene expression through the AP-1 transcription factor pathway.
    Brain research. Molecular brain research, 1998, Jul-15, Volume: 58, Issue:1-2

    Topics: Animals; Base Sequence; Binding Sites; Chlorides; Consensus Sequence; Gene Expression Regulation, Ne

1998
A role for inwardly rectifying K+ channels in differentiation of NG108-15 neuroblastoma x glioma cells.
    Journal of neurobiology, 1999, Volume: 38, Issue:4

    Topics: Animals; Cation Transport Proteins; Cell Differentiation; Cesium; Chlorides; Choline O-Acetyltransfe

1999
Sodium nitroprusside prevents chemical hypoxia-induced cell death through iron ions stimulating the activity of the Na+-Ca2+ exchanger in C6 glioma cells.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Bepridil; Calcium; Calcium Channel Block

2000
Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes.
    American journal of physiology. Cell physiology, 2000, Volume: 278, Issue:4

    Topics: Acids; Astrocytes; Bicarbonates; Buffers; Carbon Dioxide; Chlorides; DNA Mutational Analysis; DNA, C

2000
Contribution of anion transporters to the acidosis-induced swelling and intracellular acidification of glial cells.
    Journal of neurochemistry, 2000, Volume: 75, Issue:1

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anions; Antiporters; Bicarbonates; Bumeta

2000
Zinc-65 imaging of rat brain tumors.
    Cancer research, 2001, Jul-01, Volume: 61, Issue:13

    Topics: Animals; Autoradiography; Brain; Brain Neoplasms; Carbon Radioisotopes; Chlorides; Fluorodeoxyglucos

2001
Calcium dependence of serotonin-evoked conductance in C6 glioma cells.
    Glia, 1992, Volume: 6, Issue:2

    Topics: Brain Neoplasms; Calcium; Cell Membrane; Chlorides; Glioma; Membrane Potentials; Neural Conduction;

1992
Thyrotropin-releasing hormone stimulation of phosphoinositide hydrolysis desensitizes. Evidence against mediation by protein kinase C or calcium.
    Endocrinology, 1991, Volume: 129, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cells, Cultured; Chlorides; Dose-Re

1991
Efflux and exchange of glycine by plasma membrane vesicles isolated from glioblastoma cells.
    Biochimica et biophysica acta, 1988, Dec-22, Volume: 946, Issue:2

    Topics: Azo Compounds; Biological Transport; Cell Membrane; Chlorides; Glioma; Glycine; In Vitro Techniques;

1988
The Na+/K+/Cl- cotransport in C6 glioma cells. Properties and role in volume regulation.
    European journal of biochemistry, 1988, Feb-01, Volume: 171, Issue:3

    Topics: Biological Transport; Bumetanide; Carrier Proteins; Cells, Cultured; Chlorides; Flow Cytometry; Furo

1988
Sulfate-chloride exchange transport in a glioma cell line.
    Biochimica et biophysica acta, 1986, Feb-27, Volume: 855, Issue:2

    Topics: Animals; Biological Transport; Cell Line; Chlorides; Chlorine; Glioma; Kinetics; Potassium; Radioiso

1986
The analysis of body water compartments in postoperative craniotomy patients. 3. The effects of dexamethasone.
    Journal of neurosurgery, 1969, Volume: 31, Issue:4

    Topics: Adult; Astrocytoma; Body Fluids; Body Weight; Brain Neoplasms; Chlorides; Craniotomy; Dexamethasone;

1969
Adenosine deaminase in cerebrospinal fluid.
    Enzymologia, 1972, Dec-31, Volume: 43, Issue:6

    Topics: Adenosine; Adolescent; Adult; Aged; Aminohydrolases; Brain; Brain Neoplasms; Central Nervous System

1972
Effect of ethacrynic acid on lowering of intracranial pressure.
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:12

    Topics: Adolescent; Adult; Brain Edema; Brain Neoplasms; Child; Chlorides; Craniocerebral Trauma; Depression

1969