chlorine and Glioma
chlorine has been researched along with Glioma in 42 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The transport of radiolabeled L-glutamic acid by LRM55 glioma cells in culture was examined." | 7.67 | Characterization of L-glutamic acid transport by glioma cells in culture: evidence for sodium-independent, chloride-dependent high affinity influx. ( Martin, DL; Waniewski, RA, 1984) |
| "Swelling of C6 glioma cells in hypotonic medium (180 mOsm) results in two- to three-fold activation of K+ (86Rb+) influx suppressed by 10 microM bumetanide." | 3.69 | Swelling-induced activation of Na+,K+,2Cl- cotransport in C6 glioma cells: kinetic properties and intracellular signalling mechanisms. ( Aksentsev, SL; Fedulov, AS; Konev, SV; Kvacheva, ZB; Mezen, NI; Mongin, AA; Orlov, SN, 1996) |
| "C6 glioma cells accumulate the organic osmolyte inositol in response to chronic hypertonic stress." | 3.68 | Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux. ( Jackson, PS; Strange, K, 1993) |
| "The transport of radiolabeled L-glutamic acid by LRM55 glioma cells in culture was examined." | 3.67 | Characterization of L-glutamic acid transport by glioma cells in culture: evidence for sodium-independent, chloride-dependent high affinity influx. ( Martin, DL; Waniewski, RA, 1984) |
| "Glioma is a lethal malignant brain cancer, and many reports have shown that abnormalities in the behavior of water and ion channels play an important role in regulating tumor proliferation, migration, apoptosis, and differentiation." | 1.62 | Prediction of LncRNA-encoded small peptides in glioma and oligomer channel functional analysis using in silico approaches. ( Cao, Y; Lee, I; Meng, X; Sun, J; Wang, W; Yang, R; Zhang, W, 2021) |
| "Brain gliomas are highly epileptogenic." | 1.40 | Cortical GABAergic excitation contributes to epileptic activities around human glioma. ( Baulac, M; Bielle, F; Capelle, L; Chazal, G; Cresto, N; Devaux, B; Duyckaerts, C; Huberfeld, G; Kourdougli, N; Le Van Quyen, M; Miles, R; Pallud, J; Pellegrino, C; Rivera, C; Varlet, P, 2014) |
| "Malignant gliomas are highly invasive brain cancers that carry a dismal prognosis." | 1.39 | Calcium entry via TRPC1 channels activates chloride currents in human glioma cells. ( Cuddapah, VA; Sontheimer, H; Turner, KL, 2013) |
| "High-grade gliomas are devastating brain tumors associated with a mean survival of <50 weeks." | 1.33 | High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model. ( Bajenaru, ML; Bock, NA; Clarke, L; Guha, A; Gutmann, DH; Henkelman, RM; Herlyn, D; Kaplan, D; Karim, Z; Lavoie, JF; Purev, E; Qian, B; Reti, R; Sabha, N; Scheidenhelm, DK; Shannon, P; Swoboda, R; Tong, A; Wei, Q, 2006) |
| "This implies that gliomas are dependent upon dynamic HCO(-)(3)-independent H(+) buffering pathways such as the type 1 Na(+)/H(+) exchanger (NHE1)." | 1.31 | Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes. ( Cala, PM; Gorin, FA; Jorgensen, NK; McLean, LA; Roscoe, J, 2000) |
| "The present findings demonstrate that brain tumors can be imaged with radioactive zinc." | 1.31 | Zinc-65 imaging of rat brain tumors. ( Enomoto, S; Oku, N; Takeda, A; Tamano, H, 2001) |
| " Since lithium requires chronic administration for therapeutic efficacy, and because its beneficial effects last well beyond its discontinuation, it has been postulated that lithium may exert major effects at the genomic level." | 1.30 | Lithium stimulates gene expression through the AP-1 transcription factor pathway. ( Chen, G; Huang, LD; Manji, HK; Yuan, PX, 1998) |
Research
Studies (42)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (23.81) | 18.7374 |
| 1990's | 11 (26.19) | 18.2507 |
| 2000's | 12 (28.57) | 29.6817 |
| 2010's | 7 (16.67) | 24.3611 |
| 2020's | 2 (4.76) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Cao, Y | 1 |
| Yang, R | 1 |
| Lee, I | 1 |
| Zhang, W | 1 |
| Sun, J | 1 |
| Meng, X | 1 |
| Wang, W | 1 |
| Stepanenko, AA | 1 |
| Sosnovtseva, AO | 1 |
| Valikhov, MP | 1 |
| Chekhonin, VP | 1 |
| Wang, Y | 1 |
| Zhang, S | 1 |
| Li, SJ | 1 |
| Pallud, J | 1 |
| Le Van Quyen, M | 1 |
| Bielle, F | 1 |
| Pellegrino, C | 1 |
| Varlet, P | 1 |
| Cresto, N | 1 |
| Baulac, M | 1 |
| Duyckaerts, C | 1 |
| Kourdougli, N | 1 |
| Chazal, G | 1 |
| Devaux, B | 1 |
| Rivera, C | 1 |
| Miles, R | 1 |
| Capelle, L | 1 |
| Huberfeld, G | 1 |
| Di Angelantonio, S | 1 |
| Murana, E | 1 |
| Cocco, S | 1 |
| Scala, F | 1 |
| Bertollini, C | 1 |
| Molinari, MG | 1 |
| Lauro, C | 1 |
| Bregestovski, P | 1 |
| Limatola, C | 1 |
| Ragozzino, D | 1 |
| Habela, CW | 3 |
| Olsen, ML | 2 |
| Sontheimer, H | 6 |
| Rouzaire-Dubois, B | 1 |
| Ouanounou, G | 1 |
| O'Regan, S | 1 |
| Dubois, JM | 1 |
| Cuddapah, VA | 3 |
| Venkatpurwar, V | 1 |
| Shiras, A | 1 |
| Pokharkar, V | 1 |
| Watkins, S | 1 |
| Moore, LS | 1 |
| Barclay, TT | 1 |
| Turner, KL | 1 |
| Cai, Z | 1 |
| Song, F | 1 |
| Yang, MS | 1 |
| Schade, S | 1 |
| Lyons, SA | 1 |
| Amaral, MD | 1 |
| Toimela, T | 1 |
| Mäenpää, H | 1 |
| Mannerström, M | 1 |
| Tähti, H | 1 |
| Tauro, JR | 1 |
| Gemeinhart, RA | 1 |
| Wei, Q | 1 |
| Clarke, L | 1 |
| Scheidenhelm, DK | 1 |
| Qian, B | 1 |
| Tong, A | 1 |
| Sabha, N | 1 |
| Karim, Z | 1 |
| Bock, NA | 1 |
| Reti, R | 1 |
| Swoboda, R | 1 |
| Purev, E | 1 |
| Lavoie, JF | 1 |
| Bajenaru, ML | 1 |
| Shannon, P | 1 |
| Herlyn, D | 1 |
| Kaplan, D | 1 |
| Henkelman, RM | 1 |
| Gutmann, DH | 1 |
| Guha, A | 1 |
| Ernest, NJ | 1 |
| Waniewski, RA | 1 |
| Martin, DL | 3 |
| Wolpaw, EW | 2 |
| Nederman, T | 1 |
| Acker, H | 1 |
| Carlsson, J | 1 |
| Pinegin, LE | 1 |
| Dolzhenko, DA | 1 |
| Kato, K | 1 |
| Hasegawa, K | 1 |
| Goto, S | 1 |
| Inaguma, Y | 1 |
| Jackson, PS | 1 |
| Strange, K | 3 |
| McManus, ML | 1 |
| Mountian, I | 1 |
| Chou, KY | 1 |
| Van Driessche, W | 1 |
| Mongin, AA | 1 |
| Aksentsev, SL | 1 |
| Orlov, SN | 1 |
| Kvacheva, ZB | 1 |
| Mezen, NI | 1 |
| Fedulov, AS | 1 |
| Konev, SV | 1 |
| Emma, F | 1 |
| McManus, M | 1 |
| Kaiho, H | 1 |
| Matsuoka, I | 1 |
| Kimura, J | 1 |
| Nakanishi, H | 1 |
| Yuan, PX | 1 |
| Chen, G | 1 |
| Huang, LD | 1 |
| Manji, HK | 1 |
| Pancrazio, JJ | 1 |
| Ma, W | 1 |
| Grant, GM | 1 |
| Shaffer, KM | 1 |
| Kao, WY | 1 |
| Liu, QY | 1 |
| Manos, P | 1 |
| Barker, JL | 1 |
| Stenger, DA | 1 |
| Amoroso, S | 1 |
| Tortiglione, A | 1 |
| Secondo, A | 1 |
| Catalano, A | 1 |
| Montagnani, S | 1 |
| Di Renzo, G | 1 |
| Annunziato, L | 1 |
| McLean, LA | 1 |
| Roscoe, J | 1 |
| Jorgensen, NK | 1 |
| Gorin, FA | 1 |
| Cala, PM | 1 |
| Ringel, F | 1 |
| Chang, RC | 1 |
| Staub, F | 1 |
| Baethmann, A | 1 |
| Plesnila, N | 1 |
| Takeda, A | 1 |
| Tamano, H | 1 |
| Enomoto, S | 1 |
| Oku, N | 1 |
| Manor, D | 1 |
| Moran, N | 1 |
| Segal, M | 1 |
| Perlman, JH | 1 |
| Gershengorn, MC | 1 |
| Zafra, F | 1 |
| Giménez, C | 1 |
| Chassande, O | 1 |
| Frelin, C | 1 |
| Farahifar, D | 1 |
| Jean, T | 1 |
| Lazdunski, M | 1 |
| Shenkin, HA | 1 |
| Gutterman, P | 1 |
| Hankiewicz, J | 1 |
| Lesniak, M | 1 |
| Miyazaki, Y | 1 |
| Suematsu, K | 1 |
| Nakamura, J | 1 |
Other Studies
42 other studies available for chlorine and Glioma
| Article | Year |
|---|---|
Prediction of LncRNA-encoded small peptides in glioma and oligomer channel functional analysis using in silico approaches.
Topics: Brain Neoplasms; Cell Membrane; Chlorides; Datasets as Topic; Gene Expression Regulation, Neoplastic | 2021 |
A new insight into aggregation of oncolytic adenovirus Ad5-delta-24-RGD during CsCl gradient ultracentrifugation.
Topics: A549 Cells; Adenoviridae; Adenoviridae Infections; Animals; Antioxidants; Cell Line; Cell Line, Tumo | 2021 |
Zn(2+) induces apoptosis in human highly metastatic SHG-44 glioma cells, through inhibiting activity of the voltage-gated proton channel Hv1.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chlorid | 2013 |
Cortical GABAergic excitation contributes to epileptic activities around human glioma.
Topics: Action Potentials; Brain Neoplasms; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Glioma; Glutamates | 2014 |
A role for intracellular zinc in glioma alteration of neuronal chloride equilibrium.
Topics: Animals; Brain Neoplasms; Chlorides; Coculture Techniques; Female; gamma-Aminobutyric Acid; Glioma; | 2014 |
ClC3 is a critical regulator of the cell cycle in normal and malignant glial cells.
Topics: Analysis of Variance; Angiogenesis Inhibitors; Animals; Animals, Newborn; Cell Cycle; Cell Division; | 2008 |
Sodium-dependent activity of aquaporin-1 in rat glioma cells: a new mechanism of cell volume regulation.
Topics: Animals; Aquaporin 1; Cell Size; Chlorides; Glioma; Hypotonic Solutions; Ion Channels; Isotonic Solu | 2009 |
Molecular interaction and functional regulation of ClC-3 by Ca2+/calmodulin-dependent protein kinase II (CaMKII) in human malignant glioma.
Topics: Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Chloride Chan | 2010 |
Porphyran capped gold nanoparticles as a novel carrier for delivery of anticancer drug: in vitro cytotoxicity study.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Chlorides; Doxorubicin; Drug Carriers; Drug Delivery | 2011 |
Kinase activation of ClC-3 accelerates cytoplasmic condensation during mitotic cell rounding.
Topics: Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Cycle; Cell Division; Cell Line, Tumor; Cel | 2012 |
Calcium entry via TRPC1 channels activates chloride currents in human glioma cells.
Topics: Calcium; Chloride Channels; Chlorides; Electric Conductivity; Glioma; Humans; TRPC Cation Channels | 2013 |
Capillary liquid chromatographic-high-resolution mass spectrometric analysis of ribonucleotides.
Topics: Cell Extracts; Chlorides; Chromatography, High Pressure Liquid; Glioma; Hydrogen-Ion Concentration; | 2002 |
Expression of voltage-gated chloride channels in human glioma cells.
Topics: Antibodies; Astrocytoma; Biopsy; Blotting, Western; Cell Membrane; Chloride Channels; Chlorides; CLC | 2003 |
Development of an in vitro blood-brain barrier model-cytotoxicity of mercury and aluminum.
Topics: Aluminum Chloride; Aluminum Compounds; Animals; Blood-Brain Barrier; Cell Line; Cell Line, Tumor; Ce | 2004 |
Development of amine-containing polymeric particles.
Topics: Amines; Biocompatible Materials; Cell Line, Tumor; Chlorides; Drug Delivery Systems; Fluoresceins; F | 2005 |
High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model.
Topics: Animals; Brain Neoplasms; Chlorides; Contrast Media; Disease Models, Animal; ErbB Receptors; Gene Ex | 2006 |
Cytoplasmic condensation is both necessary and sufficient to induce apoptotic cell death.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Apoptosis; Caspases; Cell Death; Cell Line, Tumor; | 2008 |
Characterization of L-glutamic acid transport by glioma cells in culture: evidence for sodium-independent, chloride-dependent high affinity influx.
Topics: Animals; Biological Transport; Cells, Cultured; Chlorides; Glioma; Glutamates; Glutamic Acid; Gramic | 1984 |
Cl- transport in a glioma cell line: evidence for two transport mechanisms.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Astrocytes; Bicarbonates; Cell | 1984 |
Penetration of substances into tumor tissue: a methodological study with microelectrodes and cellular spheroids.
Topics: Biological Transport; Calcium; Cations; Cell Aggregation; Cells, Cultured; Chlorides; Cytological Te | 1983 |
[Effect of furosemide on intracranial pressure in patients with intracranial hypertension].
Topics: Brain Diseases; Brain Neoplasms; Chlorides; Diuresis; Furosemide; Glioma; Humans; Intracranial Press | 1983 |
Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27.
Topics: Arsenates; Cadmium; Cadmium Chloride; Cell Line; Centrifugation, Density Gradient; Chlorides; Choler | 1994 |
Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux.
Topics: Animals; Biological Transport; Cell Line; Chloride Channels; Chlorides; Fatty Acids, Nonesterified; | 1993 |
Acute volume regulation of brain cells in response to hypertonic challenge.
Topics: Animals; Brain Neoplasms; Bumetanide; Cell Size; Chlorides; Glioma; Hypertonic Solutions; In Vitro T | 1993 |
Electrolyte transport mechanisms involved in regulatory volume increase in C6 glioma cells.
Topics: Animals; Antiporters; Bicarbonates; Biological Transport, Active; Carrier Proteins; Cell Size; Chlor | 1996 |
Swelling-induced activation of Na+,K+,2Cl- cotransport in C6 glioma cells: kinetic properties and intracellular signalling mechanisms.
Topics: Bumetanide; Carrier Proteins; Cell Size; Chlorides; Diuretics; Glioma; Hypotonic Solutions; Ion Exch | 1996 |
Intracellular electrolytes regulate the volume set point of the organic osmolyte/anion channel VSOAC.
Topics: Animals; Chlorides; Glioma; Homeostasis; Hypertonic Solutions; Hypotonic Solutions; Intracellular Fl | 1997 |
Identification of P2X7 (P2Z) receptor in N18TG-2 cells and NG108-15 cells.
Topics: Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Cations; Chlorides; Dose-Resp | 1998 |
Lithium stimulates gene expression through the AP-1 transcription factor pathway.
Topics: Animals; Base Sequence; Binding Sites; Chlorides; Consensus Sequence; Gene Expression Regulation, Ne | 1998 |
A role for inwardly rectifying K+ channels in differentiation of NG108-15 neuroblastoma x glioma cells.
Topics: Animals; Cation Transport Proteins; Cell Differentiation; Cesium; Chlorides; Choline O-Acetyltransfe | 1999 |
Sodium nitroprusside prevents chemical hypoxia-induced cell death through iron ions stimulating the activity of the Na+-Ca2+ exchanger in C6 glioma cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Bepridil; Calcium; Calcium Channel Block | 2000 |
Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes.
Topics: Acids; Astrocytes; Bicarbonates; Buffers; Carbon Dioxide; Chlorides; DNA Mutational Analysis; DNA, C | 2000 |
Contribution of anion transporters to the acidosis-induced swelling and intracellular acidification of glial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anions; Antiporters; Bicarbonates; Bumeta | 2000 |
Zinc-65 imaging of rat brain tumors.
Topics: Animals; Autoradiography; Brain; Brain Neoplasms; Carbon Radioisotopes; Chlorides; Fluorodeoxyglucos | 2001 |
Calcium dependence of serotonin-evoked conductance in C6 glioma cells.
Topics: Brain Neoplasms; Calcium; Cell Membrane; Chlorides; Glioma; Membrane Potentials; Neural Conduction; | 1992 |
Thyrotropin-releasing hormone stimulation of phosphoinositide hydrolysis desensitizes. Evidence against mediation by protein kinase C or calcium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cells, Cultured; Chlorides; Dose-Re | 1991 |
Efflux and exchange of glycine by plasma membrane vesicles isolated from glioblastoma cells.
Topics: Azo Compounds; Biological Transport; Cell Membrane; Chlorides; Glioma; Glycine; In Vitro Techniques; | 1988 |
The Na+/K+/Cl- cotransport in C6 glioma cells. Properties and role in volume regulation.
Topics: Biological Transport; Bumetanide; Carrier Proteins; Cells, Cultured; Chlorides; Flow Cytometry; Furo | 1988 |
Sulfate-chloride exchange transport in a glioma cell line.
Topics: Animals; Biological Transport; Cell Line; Chlorides; Chlorine; Glioma; Kinetics; Potassium; Radioiso | 1986 |
The analysis of body water compartments in postoperative craniotomy patients. 3. The effects of dexamethasone.
Topics: Adult; Astrocytoma; Body Fluids; Body Weight; Brain Neoplasms; Chlorides; Craniotomy; Dexamethasone; | 1969 |
Adenosine deaminase in cerebrospinal fluid.
Topics: Adenosine; Adolescent; Adult; Aged; Aminohydrolases; Brain; Brain Neoplasms; Central Nervous System | 1972 |
Effect of ethacrynic acid on lowering of intracranial pressure.
Topics: Adolescent; Adult; Brain Edema; Brain Neoplasms; Child; Chlorides; Craniocerebral Trauma; Depression | 1969 |