chlorine has been researched along with Glaucoma in 17 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results confirm the beneficial effect of supplemental alkalinization for such CAI-induced symptoms in somewhat less than half of the affected patients and suggest the need for long-term studies in which the dosage of sodium acetate is titrated in relation to measured changes in the level of metabolic acidosis." | 2.65 | The influence of supplemental sodium acetate on carbonic anhydrase inhibitor-induced side effects. ( Arrigg, CA; Epstein, DL; Giovanoni, R; Grant, WM, 1981) |
| "Proximal renal tubular acidosis associated with ocular abnormalities such as band keratopathy, glaucoma, and cataracts is caused by mutations in the Na(+)-HCO(3)(-) cotransporter (NBC-1)." | 1.31 | Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis. ( Amano, S; Araie, M; Endou, H; Fujita, T; Goto, A; Hara, C; Hara, M; Ibaraki, N; Igarashi, T; Inatomi, J; Ishii, Y; Kagaya, H; Kawakami, H; Kunimi, M; Moriyama, N; Noiri, E; Oshika, T; Satoh, H; Seki, G; Tsukamoto, K; Usui, T, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, Y | 1 |
| Jin, W | 1 |
| Sun, Q | 1 |
| Li, N | 1 |
| Jiang, M | 1 |
| Liu, Y | 1 |
| Sun, L | 1 |
| Lucia, U | 1 |
| Grisolia, G | 1 |
| Astori, MR | 1 |
| HEMPEL, AC | 1 |
| DUNDAS, JB | 1 |
| Noecker, RJ | 1 |
| Herrygers, LA | 1 |
| Anwaruddin, R | 1 |
| Chan, KC | 1 |
| Fu, QL | 1 |
| So, KF | 1 |
| Wu, EX | 1 |
| Sarda, RP | 1 |
| Charan, H | 1 |
| Ohri, RN | 1 |
| Spaeth, GL | 1 |
| Arrigg, CA | 1 |
| Epstein, DL | 1 |
| Giovanoni, R | 1 |
| Grant, WM | 1 |
| Haskins, SC | 1 |
| Munger, RJ | 1 |
| Helphrey, MG | 1 |
| Gilroy, BA | 1 |
| Patz, JD | 1 |
| Steele, MD | 1 |
| Shapiro, W | 1 |
| Usui, T | 1 |
| Hara, M | 1 |
| Satoh, H | 1 |
| Moriyama, N | 1 |
| Kagaya, H | 1 |
| Amano, S | 1 |
| Oshika, T | 1 |
| Ishii, Y | 1 |
| Ibaraki, N | 1 |
| Hara, C | 1 |
| Kunimi, M | 1 |
| Noiri, E | 1 |
| Tsukamoto, K | 1 |
| Inatomi, J | 1 |
| Kawakami, H | 1 |
| Endou, H | 1 |
| Igarashi, T | 1 |
| Goto, A | 1 |
| Fujita, T | 1 |
| Araie, M | 1 |
| Seki, G | 1 |
| Vibat, CR | 1 |
| Holland, MJ | 1 |
| Kang, JJ | 1 |
| Putney, LK | 1 |
| O'Donnell, ME | 1 |
| Mennear, JH | 1 |
| Cherniavskiĭ, GIa | 1 |
| Gurtovaia, EE | 1 |
| Mogilevskaia, FIa | 1 |
| Suprun, AV | 1 |
| Fedorova, SM | 1 |
| Maren, TH | 1 |
| Harris, LS | 1 |
| Mittag, TW | 1 |
| Galin, MA | 1 |
| Sevcík, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of BAK on the Blood Aqueous Barrier of Pseudophakic Patients[NCT01280110] | Phase 4 | 44 participants (Actual) | Interventional | 2011-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Aqueous humor flare indicates the degree of a break in the blood-aqueous barrier. It is objectively measured with a Laser flare meter. (NCT01280110)
Timeframe: Baseline, 15 days and 30 days.
| Intervention | photons/msec (Mean) | ||
|---|---|---|---|
| Baseline | 15 days | 30 days | |
| Preservative-free Lubricating Drops | 9.3 | 8.4 | 8.4 |
| Preserved (BAK 0.006%) Lubricating Drop | 8.4 | 11.4 | 11.9 |
Macular thickness will be measured with an Optical coherence tomography (OCT). Measures 5% under the normal population according to the OCT software will be considered break in the blood-retina barrier. (NCT01280110)
Timeframe: Baseline, 15 days and 30 days.
| Intervention | μm (Mean) | ||
|---|---|---|---|
| Baseline | 15 days | 30 days | |
| Preservative-free Lubricating Drops | 259.2 | 256.4 | 258.3 |
| Preserved (BAK 0.006%) Lubricating Drop | 258.5 | 254.9 | 255.9 |
1 trial available for chlorine and Glaucoma
| Article | Year |
|---|---|
The influence of supplemental sodium acetate on carbonic anhydrase inhibitor-induced side effects.
Topics: Acetates; Acidosis; Adult; Aged; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Chlorides; Clinical | 1981 |
16 other studies available for chlorine and Glaucoma
| Article | Year |
|---|---|
Role of the chloride channel blocker in the formation of filtering tract scars after glaucoma surgery in rats.
Topics: Animals; Chloride Channels; Chlorides; Cicatrix; Glaucoma; Intraocular Pressure; Rats; Rats, Sprague | 2023 |
Constructal law analysis of Cl
Topics: Aqueous Humor; Chlorides; Glaucoma; Humans; Models, Theoretical | 2017 |
THE RELATIONSHIP OF THE MAJOR CONSTITUENTS OF BLOOD PLASMA TO THE INTRAOCULAR PRESSURE DURING PHASIC VARIATIONS AND AMMONIUM CHLORIDE ADMINISTRATION.
Topics: Ammonium Chloride; Bicarbonates; Blood; Blood Proteins; Chlorides; Glaucoma; Humans; Intraocular Pre | 1964 |
LOWE'S SYNDROME.
Topics: Acidosis; Albuminuria; Alkalies; Anti-Bacterial Agents; Blood; Bone Diseases; Calcium; Cataract; Chi | 1964 |
Corneal and conjunctival changes caused by commonly used glaucoma medications.
Topics: Animals; Antihypertensive Agents; Benzalkonium Compounds; Chlorides; Conjunctiva; Conjunctival Disea | 2004 |
Evaluation of the visual system in a rat model of chronic glaucoma using manganese-enhanced magnetic resonance imaging.
Topics: Animals; Chlorides; Chronic Disease; Contrast Media; Diffusion Magnetic Resonance Imaging; Disease M | 2007 |
Ocular tension and electrolyte changes after glycerol. A study of blood and aqueous humor in normal rabbits and those in which intraocular pressure has been raised artificially.
Topics: Animals; Aqueous Humor; Chlorides; Glaucoma; Glycerol; Intraocular Pressure; Potassium; Rabbits; Sod | 1967 |
Potassium, acetazolamide, and intraocular pressure.
Topics: Acetazolamide; Adult; Aged; Bicarbonates; Child; Chlorides; Electrocardiography; Female; Glaucoma; H | 1967 |
Effect of acetazolamide in blood acid-base and electrolyte values in dogs.
Topics: Acetazolamide; Acid-Base Equilibrium; Administration, Oral; Animals; Carbon Dioxide; Chlorides; Dog | 1981 |
Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis, Renal Tubular; Amiloride; Animals; Bicar | 2001 |
Quantitation of Na+-K+-2Cl- cotransport splice variants in human tissues using kinetic polymerase chain reaction.
Topics: Alternative Splicing; Amino Acid Sequence; Base Sequence; Cells, Cultured; Chlorides; DNA Primers; G | 2001 |
Familial pharmacology.
Topics: Adrenal Cortex Hormones; Chlorides; Coumarins; Drug Resistance; Forecasting; Glaucoma; Glucosephosph | 1977 |
[Experience with a drug complex for stabilization of visual functions in glaucomatous patients].
Topics: Adenosine Triphosphate; Adult; Aged; Chlorides; Choline; Drug Therapy, Combination; Glaucoma; Humans | 1976 |
The rates of movement of Na+, Cl-, and HCO-3 from plasma to posterior chamber: effect of acetazolamide and relation to the treatment of glaucoma.
Topics: Acetazolamide; Animals; Aqueous Humor; Bicarbonates; Biological Transport, Active; Chlorides; Dogs; | 1976 |
Aqueous dynamics of pilocarpine-treated eyes. The influence of topically applied epinephrine.
Topics: Aqueous Humor; Boric Acids; Chlorides; Drug Synergism; Epinephrine; Follow-Up Studies; Glaucoma; Hum | 1971 |
[Effect of bicarbonates and chlorides on the flow equilibrium of the eye].
Topics: Acid-Base Equilibrium; Aqueous Humor; Bicarbonates; Chlorides; Glaucoma; Humans; Infusions, Parenter | 1969 |