chlorine has been researched along with Genetic Predisposition in 35 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To characterize the time course and physiologic significance of decline in serum immunoreactive trypsinogen (IRT) levels in infants with cystic fibrosis (CF) by mode of diagnosis and genotype, and to examine IRT heritability." | 7.73 | Genetic and physiologic correlates of longitudinal immunoreactive trypsinogen decline in infants with cystic fibrosis identified through newborn screening. ( Accurso, FJ; Corey, M; Hokanson, JE; Marshall, JA; Sommer, SS; Sontag, MK; Zerbe, GO, 2006) |
| "To determine how CD73 activity influences in vivo thrombosis, the time to ferric chloride-induced arterial thrombosis was measured in CD73-null mice." | 3.83 | Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice. ( Chepurko, E; Covarrubias, R; Cowan, PJ; Dwyer, KM; Gumina, RJ; Huttinger, R; Huttinger, ZM; Novitskaya, T; Reynolds, A; Robson, SC; Stanfill, K; Wheeler, DG, 2016) |
| "To characterize the time course and physiologic significance of decline in serum immunoreactive trypsinogen (IRT) levels in infants with cystic fibrosis (CF) by mode of diagnosis and genotype, and to examine IRT heritability." | 3.73 | Genetic and physiologic correlates of longitudinal immunoreactive trypsinogen decline in infants with cystic fibrosis identified through newborn screening. ( Accurso, FJ; Corey, M; Hokanson, JE; Marshall, JA; Sommer, SS; Sontag, MK; Zerbe, GO, 2006) |
| "We tested 39 patients with idiopathic chronic pancreatitis (mean age at diagnosis, 33 years) for common mutations of CFTR and of genes encoding a trypsin inhibitor (PSTI) and trypsinogen (PRSS1)." | 3.71 | Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations. ( Cohn, JA; Jowell, PS; Knowles, MR; Noone, PG; Silverman, LM; Zhou, Z, 2001) |
| "Initiation of celiac disease is triggered in the gastrointestinal tract by transglutaminase 2 (TG2) assisted deamidation of gluten peptides." | 1.46 | Towards Celiac-safe foods: Decreasing the affinity of transglutaminase 2 for gliadin by addition of ascorbyl palmitate and ZnCl ( Engstrom, N; Saenz-Méndez, P; Scheers, J; Scheers, N, 2017) |
| "Cystic fibrosis is a lethal autosomal recessive disorder usually associated with lung disease, pancreatic insufficiency and high sweat chloride levels." | 1.35 | Clinical and molecular characterization of S1118F-CFTR. ( Conoley, VG; Frederick, CA; Kappes, J; Li, C; Naren, AP; Nekkalapu, S; Penmatsa, H; Stokes, DC; Zhang, W, 2009) |
| "Platelet thrombus growth after FeCl(3)-induced acute endothelial injury was accelerated in mutant mice." | 1.31 | Characterization of a mouse model for thrombomodulin deficiency. ( Conway, EM; Cooley, BC; Hendrickson, SB; Isermann, BH; Kerlin, B; Lindner, V; Meh, DA; Mosesson, MW; Post, MJ; Shworak, NW; Ulfman, LH; von Andrian, UH; Weiler, H; Weitz, JI, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (11.43) | 18.2507 |
| 2000's | 17 (48.57) | 29.6817 |
| 2010's | 13 (37.14) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JH | 1 |
| Ousingsawat, J | 1 |
| Cabrita, I | 1 |
| Bettels, RE | 1 |
| Große-Onnebrink, J | 1 |
| Schmalstieg, C | 1 |
| Biskup, S | 1 |
| Reunert, J | 1 |
| Rust, S | 1 |
| Schreiber, R | 1 |
| Kunzelmann, K | 1 |
| Marquardt, T | 1 |
| Smith, CW | 1 |
| Thomas, SG | 1 |
| Raslan, Z | 1 |
| Patel, P | 1 |
| Byrne, M | 1 |
| Lordkipanidzé, M | 1 |
| Bem, D | 1 |
| Meyaard, L | 1 |
| Senis, YA | 1 |
| Watson, SP | 1 |
| Mazharian, A | 1 |
| Sermet-Gaudelus, I | 1 |
| Elborn, JS | 1 |
| Puskarjov, M | 1 |
| Seja, P | 1 |
| Heron, SE | 1 |
| Williams, TC | 1 |
| Ahmad, F | 1 |
| Iona, X | 1 |
| Oliver, KL | 1 |
| Grinton, BE | 1 |
| Vutskits, L | 1 |
| Scheffer, IE | 1 |
| Petrou, S | 1 |
| Blaesse, P | 1 |
| Dibbens, LM | 1 |
| Berkovic, SF | 1 |
| Kaila, K | 1 |
| Subramaniam, S | 1 |
| Thielmann, I | 1 |
| Morowski, M | 1 |
| Pragst, I | 1 |
| Sandset, PM | 1 |
| Nieswandt, B | 1 |
| Etscheid, M | 1 |
| Kanse, SM | 1 |
| Covarrubias, R | 1 |
| Chepurko, E | 1 |
| Reynolds, A | 1 |
| Huttinger, ZM | 1 |
| Huttinger, R | 1 |
| Stanfill, K | 1 |
| Wheeler, DG | 1 |
| Novitskaya, T | 1 |
| Robson, SC | 1 |
| Dwyer, KM | 1 |
| Cowan, PJ | 1 |
| Gumina, RJ | 1 |
| Dhanesha, N | 1 |
| Prakash, P | 1 |
| Doddapattar, P | 1 |
| Khanna, I | 1 |
| Pollpeter, MJ | 1 |
| Nayak, MK | 1 |
| Staber, JM | 1 |
| Chauhan, AK | 1 |
| Engstrom, N | 1 |
| Saenz-Méndez, P | 1 |
| Scheers, J | 1 |
| Scheers, N | 1 |
| Voter, KZ | 1 |
| Ren, CL | 1 |
| Corbetta, S | 1 |
| Eller-Vainicher, C | 1 |
| Frigerio, M | 1 |
| Valaperta, R | 1 |
| Costa, E | 1 |
| Vicentini, L | 1 |
| Baccarelli, A | 1 |
| Beck-Peccoz, P | 1 |
| Spada, A | 1 |
| Grand, T | 1 |
| Mordasini, D | 1 |
| L'Hoste, S | 1 |
| Pennaforte, T | 1 |
| Genete, M | 1 |
| Biyeyeme, MJ | 1 |
| Vargas-Poussou, R | 1 |
| Blanchard, A | 1 |
| Teulon, J | 1 |
| Lourdel, S | 1 |
| Penmatsa, H | 1 |
| Frederick, CA | 1 |
| Nekkalapu, S | 1 |
| Conoley, VG | 1 |
| Zhang, W | 1 |
| Li, C | 1 |
| Kappes, J | 1 |
| Stokes, DC | 1 |
| Naren, AP | 1 |
| Burgel, PR | 1 |
| Fajac, I | 1 |
| Hubert, D | 1 |
| Grenet, D | 1 |
| Stremler, N | 1 |
| Roussey, M | 1 |
| Siret, D | 1 |
| Languepin, J | 1 |
| Mely, L | 1 |
| Fanton, A | 1 |
| Labbé, A | 1 |
| Domblides, P | 1 |
| Vic, P | 1 |
| Dagorne, M | 1 |
| Reynaud-Gaubert, M | 1 |
| Counil, F | 1 |
| Varaigne, F | 1 |
| Bienvenu, T | 1 |
| Bellis, G | 1 |
| Dusser, D | 1 |
| Martin, V | 1 |
| Guillermet-Guibert, J | 1 |
| Chicanne, G | 1 |
| Cabou, C | 1 |
| Jandrot-Perrus, M | 1 |
| Plantavid, M | 1 |
| Vanhaesebroeck, B | 1 |
| Payrastre, B | 1 |
| Gratacap, MP | 1 |
| Hooman, N | 1 |
| Jafari, D | 1 |
| Jalali-Farahani, S | 1 |
| Lahouti Harahdashti, A | 1 |
| Anagnostopoulou, P | 1 |
| Riederer, B | 1 |
| Duerr, J | 1 |
| Michel, S | 1 |
| Binia, A | 1 |
| Agrawal, R | 1 |
| Liu, X | 1 |
| Kalitzki, K | 1 |
| Xiao, F | 1 |
| Chen, M | 1 |
| Schatterny, J | 1 |
| Hartmann, D | 1 |
| Thum, T | 1 |
| Kabesch, M | 1 |
| Soleimani, M | 2 |
| Seidler, U | 1 |
| Mall, MA | 1 |
| Aboud, AA | 1 |
| Tidball, AM | 1 |
| Kumar, KK | 1 |
| Neely, MD | 1 |
| Ess, KC | 1 |
| Erikson, KM | 1 |
| Bowman, AB | 1 |
| Keim, V | 1 |
| Aviv, A | 1 |
| Hollenberg, NK | 1 |
| Weder, A | 1 |
| Jeck, N | 1 |
| Waldegger, S | 1 |
| Lampert, A | 1 |
| Boehmer, C | 1 |
| Waldegger, P | 1 |
| Lang, PA | 1 |
| Wissinger, B | 1 |
| Friedrich, B | 1 |
| Risler, T | 1 |
| Moehle, R | 1 |
| Lang, UE | 1 |
| Zill, P | 1 |
| Bondy, B | 1 |
| Schaeffeler, E | 1 |
| Asante-Poku, S | 1 |
| Seyberth, H | 1 |
| Schwab, M | 1 |
| Lang, F | 1 |
| Gamba, G | 1 |
| Schmidlin, O | 1 |
| Tanaka, M | 1 |
| Bollen, AW | 1 |
| Yi, SL | 1 |
| Morris, RC | 1 |
| Cantin, AM | 1 |
| Hanrahan, JW | 1 |
| Bilodeau, G | 1 |
| Ellis, L | 1 |
| Dupuis, A | 1 |
| Liao, J | 1 |
| Zielenski, J | 1 |
| Durie, P | 1 |
| Sontag, MK | 1 |
| Corey, M | 1 |
| Hokanson, JE | 1 |
| Marshall, JA | 1 |
| Sommer, SS | 1 |
| Zerbe, GO | 1 |
| Accurso, FJ | 1 |
| Clark, JS | 1 |
| Vandorpe, DH | 1 |
| Chernova, MN | 1 |
| Heneghan, JF | 1 |
| Stewart, AK | 1 |
| Alper, SL | 1 |
| Paranjape, SM | 1 |
| Zeitlin, PL | 1 |
| Quinton, PM | 1 |
| Zhu, Y | 1 |
| Carmeliet, P | 1 |
| Fay, WP | 1 |
| Newman Taylor, AJ | 1 |
| Cullinan, P | 1 |
| Lympany, PA | 1 |
| Harris, JM | 1 |
| Dowdeswell, RJ | 1 |
| du Bois, RM | 1 |
| Höglund, P | 1 |
| Holmberg, C | 1 |
| Sherman, P | 1 |
| Kere, J | 1 |
| Weiler, H | 1 |
| Lindner, V | 1 |
| Kerlin, B | 1 |
| Isermann, BH | 1 |
| Hendrickson, SB | 1 |
| Cooley, BC | 1 |
| Meh, DA | 1 |
| Mosesson, MW | 1 |
| Shworak, NW | 1 |
| Post, MJ | 1 |
| Conway, EM | 1 |
| Ulfman, LH | 1 |
| von Andrian, UH | 1 |
| Weitz, JI | 1 |
| Noone, PG | 1 |
| Zhou, Z | 1 |
| Silverman, LM | 1 |
| Jowell, PS | 1 |
| Knowles, MR | 1 |
| Cohn, JA | 1 |
| Buck, KJ | 1 |
| McQuilkin, SJ | 1 |
| Harris, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Relationship Between Polymorphisms of TRPV1 and KCC2 Gene in Children With Febrile Seizures[NCT04368936] | 121 participants (Actual) | Observational [Patient Registry] | 2015-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for chlorine and Genetic Predisposition
| Article | Year |
|---|---|
Ivacaftor treatment in patients with cystic fibrosis and the G551D-CFTR mutation.
Topics: Adolescent; Adult; Aminophenols; Child; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Co | 2013 |
Diagnosis of cystic fibrosis.
Topics: Bronchiectasis; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dia | 2008 |
Urinary potassium excretion and sodium sensitivity in blacks.
Topics: Animals; Black People; Chlorides; Disease Models, Animal; Diuresis; Genetic Predisposition to Diseas | 2004 |
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.
Topics: Animals; Bumetanide; Cations; Chlorides; Electrochemistry; Genetic Diseases, Inborn; Genetic Predisp | 2005 |
Atypical cystic fibrosis and CFTR-related diseases.
Topics: Adolescent; Adult; Airway Obstruction; Aspergillosis, Allergic Bronchopulmonary; Aspergillus fumigat | 2008 |
Human genetics. What is good about cystic fibrosis?
Topics: Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Enterotox | 1994 |
29 other studies available for chlorine and Genetic Predisposition
| Article | Year |
|---|---|
TMEM16A deficiency: a potentially fatal neonatal disease resulting from impaired chloride currents.
Topics: Anoctamin-1; Biological Transport; Calcium; Chloride Channels; Chlorides; Cystic Fibrosis; Female; G | 2021 |
Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.
Topics: Animals; Blood Platelets; Carrier Proteins; Cells, Cultured; Chlorides; Disease Models, Animal; Enzy | 2017 |
The impact of personalised therapies on respiratory medicine.
Topics: Aminophenols; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genet | 2013 |
A variant of KCC2 from patients with febrile seizures impairs neuronal Cl- extrusion and dendritic spine formation.
Topics: Amino Acid Sequence; Animals; Australia; Blotting, Western; Chlorides; Dendritic Spines; Genetic Pre | 2014 |
Defective thrombus formation in mice lacking endogenous factor VII activating protease (FSAP).
Topics: Animals; Blood Coagulation Tests; Carotid Arteries; Carotid Artery Diseases; Chlorides; Collagen; Di | 2015 |
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; | 2016 |
Endothelial Cell-Derived von Willebrand Factor Is the Major Determinant That Mediates von Willebrand Factor-Dependent Acute Ischemic Stroke by Promoting Postischemic Thrombo-Inflammation.
Topics: ADAMTS13 Protein; Animals; Blood Platelets; Bone Marrow Transplantation; Carotid Artery Diseases; Ch | 2016 |
Towards Celiac-safe foods: Decreasing the affinity of transglutaminase 2 for gliadin by addition of ascorbyl palmitate and ZnCl
Topics: Ascorbic Acid; Celiac Disease; Chlorides; Drug Evaluation, Preclinical; Epitopes, T-Lymphocyte; Food | 2017 |
Analysis of the 206M polymorphic variant of the SLC26A6 gene encoding a Cl- oxalate transporter in patients with primary hyperparathyroidism.
Topics: Aged; Chlorides; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Hyperp | 2009 |
Novel CLCN5 mutations in patients with Dent's disease result in altered ion currents or impaired exchanger processing.
Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Line; Cell Membrane; Child; Child, Preschoo | 2009 |
Clinical and molecular characterization of S1118F-CFTR.
Topics: Blotting, Western; Cells, Cultured; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conduc | 2009 |
Non-classic cystic fibrosis associated with D1152H CFTR mutation.
Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Child; Child, Preschool; Chlorides; Cohort Studies | 2010 |
Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo.
Topics: Animals; Bleeding Time; Blood Platelets; Cell Lineage; Cells, Cultured; Chlorides; Class I Phosphati | 2010 |
An infant with alternating metabolic acidosis and alkalosis: question.
Topics: Acidosis; Acute Kidney Injury; Alkalosis; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane | 2012 |
SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation.
Topics: 3' Untranslated Regions; Airway Obstruction; Animals; Antiporters; Asthma; Bronchitis; Calcium; Chil | 2012 |
Genetic risk for Parkinson's disease correlates with alterations in neuronal manganese sensitivity between two human subjects.
Topics: Biosensing Techniques; Case-Control Studies; Cell Line; Cell Survival; Chlorides; Dose-Response Rela | 2012 |
[Molecular pathogenesis of pancreatitis].
Topics: Chlorides; DNA Mutational Analysis; Genetic Predisposition to Disease; Humans; Membrane Transport Pr | 2002 |
Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension.
Topics: Adult; Amino Acid Substitution; Animals; Anion Transport Proteins; Black People; Chloride Channels; | 2004 |
Chloride-dominant salt sensitivity in the stroke-prone spontaneously hypertensive rat.
Topics: Animals; Bicarbonates; Blood Pressure; Body Weight; Chlorides; Creatinine; Drug Combinations; Electr | 2005 |
Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers.
Topics: Adult; Analysis of Variance; Blotting, Northern; Blotting, Western; Case-Control Studies; Cells, Cul | 2006 |
Genetic and physiologic correlates of longitudinal immunoreactive trypsinogen decline in infants with cystic fibrosis identified through newborn screening.
Topics: Biomarkers; Body Height; Body Weight; Chlorides; Cystic Fibrosis; DNA Mutational Analysis; Fats; Fec | 2006 |
Species differences in Cl- affinity and in electrogenicity of SLC26A6-mediated oxalate/Cl- exchange correlate with the distinct human and mouse susceptibilities to nephrolithiasis.
Topics: Animals; Antiporters; Chlorides; Female; Genetic Predisposition to Disease; Humans; Hydrogen-Ion Con | 2008 |
The role of SLC26A6-mediated chloride/oxalate exchange in causing susceptibility to nephrolithiasis.
Topics: Animals; Antiporters; Chlorides; Genetic Predisposition to Disease; Humans; Membrane Transport Prote | 2008 |
Plasminogen activator inhibitor-1 is a major determinant of arterial thrombolysis resistance.
Topics: Animals; Blood Platelets; Carotid Arteries; Carotid Stenosis; Chlorides; Ferric Compounds; Genetic P | 1999 |
Interaction of HLA phenotype and exposure intensity in sensitization to complex platinum salts.
Topics: Adult; Chlorides; Female; Genetic Predisposition to Disease; HLA Antigens; HLA-DR3 Antigen; HLA-DR6 | 1999 |
Distinct outcomes of chloride diarrhoea in two siblings with identical genetic background of the disease: implications for early diagnosis and treatment.
Topics: Chloride Channels; Chlorides; Diarrhea; Genetic Predisposition to Disease; Heterozygote; Humans; Inf | 2001 |
Characterization of a mouse model for thrombomodulin deficiency.
Topics: Animals; Blood Coagulation; Carotid Artery Thrombosis; Chlorides; Cytokines; Ferric Compounds; Fibri | 2001 |
Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.
Topics: Adolescent; Adult; Alleles; alpha-Amylases; Child; Chlorides; Cystic Fibrosis; Epithelium; Female; G | 2001 |
Modulation of gamma-aminobutyric acidA receptor-operated chloride channels by benzodiazepine inverse agonists is related to genetic differences in ethanol withdrawal seizure severity.
Topics: Animals; Benzodiazepines; Carbolines; Chloride Channels; Chlorides; Convulsants; Ethanol; Flunitraze | 1991 |