Page last updated: 2024-10-17

chlorine and Endotoxin Shock

chlorine has been researched along with Endotoxin Shock in 24 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Research Excerpts

ExcerptRelevanceReference
"To determine if acidosis, induced by dilute hydrochloric acid (HCl) infusion, will increase circulating inflammatory mediator levels in an experimental model of severe sepsis in rats."3.73Hyperchloremic acidosis increases circulating inflammatory molecules in experimental sepsis. ( Almasri, E; Kellum, JA; Song, M, 2006)
"Thirty consecutive patients with septic shock were prospectively included on ICU admission."2.77Defining metabolic acidosis in patients with septic shock using Stewart approach. ( Mallat, J; Michel, D; Salaun, P; Thevenin, D; Tronchon, L, 2012)
"Patients with septic shock, defined according to Sepsis-2 definition, were eligible."1.62Does Chloride Intake at the Early Phase of Septic Shock Resuscitation Impact on Renal Outcome? ( Aubron, C; Balzer, T; Chapalain, X; Darreau, C; Delbove, A; Egreteau, PY; Huet, O; Jacquier, S; Lerolle, N; Martino, F; Saint-Martin, M, 2021)
"Retrospective analysis of a pediatric septic shock database."1.48Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock. ( Allen, GL; Anas, N; Bigham, MT; Checchia, PA; Cvijanovich, NZ; Fitzgerald, JC; Freishtat, RJ; Gedeit, R; Gertz, S; Grunwell, JR; Hall, M; Meyer, K; Nowak, J; Quasney, M; Raj, SS; Stenson, EK; Thomas, NJ; Weiss, SL; Wong, HR, 2018)
"Metabolic acidosis is common in septic shock, yet few data exist on its etiological temporal profile during resuscitation; this is partly due to limitations in bedside monitoring tools (base excess, anion gap)."1.34Hyperchloremia is the dominant cause of metabolic acidosis in the postresuscitation phase of pediatric meningococcal sepsis. ( Durward, A; Murdoch, IA; O'Dell, E; Tibby, SM, 2007)
"Five children with septic shock are presented who had persisting base deficit after large volume resuscitation with 0."1.31Chasing the base deficit: hyperchloraemic acidosis following 0.9% saline fluid resuscitation. ( Durward, A; Mayer, A; Murdoch, IA; Skellett, S; Tibby, SM, 2000)
"Septic shock was induced in adult baboons by the infusion of live Escherichia coli."1.27Changes in red blood cell transmembrane potential, electrolytes, and energy content in septic shock. ( Illner, H; Peitzman, AB; Shires, GT, 1983)
"Compared with control dogs, dogs with endotoxic shock had mildly, though insignificantly, increased anion gaps and significantly increased blood lactate concentrations."1.27Osmolal and anion gaps in dogs with acute endotoxic shock. ( Hauptman, JG; Tvedten, H, 1986)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19908 (33.33)18.7374
1990's2 (8.33)18.2507
2000's5 (20.83)29.6817
2010's5 (20.83)24.3611
2020's4 (16.67)2.80

Authors

AuthorsStudies
Ampuero Acuña, C1
Tomarelli Rubio, G1
Montes Franceschini, S1
Donoso Fuentes, A1
Dhanani, LY1
Totton, RR1
Jara-Quijada, E1
Pérez-Won, M1
Tabilo-Munizaga, G1
Lemus-Mondaca, R1
González-Cavieres, L1
Palma-Acevedo, A1
Herrera-Lavados, C1
Milovanovic, S1
Grzegorczyk, A1
Świątek, Ł1
Grzęda, A1
Dębczak, A1
Tyskiewicz, K1
Konkol, M1
Li, Y2
Chang, P1
Sankaran, S1
Jang, H1
Nie, Y1
Zeng, A1
Hussain, S1
Wu, JY1
Chen, X2
Shi, L2
Senapati, A1
Chetri, BK1
Mitra, S1
Shelke, RG1
Rangan, L1
Chauhan, AS1
Tiwari, M1
Indoliya, Y1
Mishra, SK1
Lavania, UC1
Chauhan, PS1
Chakrabarty, D1
Tripathi, RD1
Akaputra, R1
Hatta, M1
Massi, MN1
Djaharuddin, I1
Bukhari, A1
Aminuddin, A1
Santoso, A1
Natzir, R1
Bahar, B1
Fachri, M1
Farsida, F1
Fathimah, A1
Ubaidah, FM1
Sridiana, E1
Dwiyanti, R1
Syukri, A1
Junita, AR1
Febrianti, A1
Primaguna, MR1
Azhar, A1
Rajaure, YS1
Thapa, B1
Budhathoki, L1
Rana, SR1
Khadka, M1
Batchu, UR1
Surapaneni, JR1
Cheemalamarri, C1
Mandava, K1
Puvvada, N1
Shetty, PR1
Mv, S1
Ranjbarian, P1
Goudarzi, F1
Akya, A1
Heidarinia, H1
Farasat, A1
Rostamian, M1
Suri, K1
Rajput, N1
Sharma, P1
Omble, AD1
Kulkarni, K1
Gahlay, GK1
Fernandez Garcia, E1
Paudel, U1
Noji, MC1
Bowman, CE1
Rustgi, AK1
Pitarresi, JR1
Wellen, KE1
Arany, Z1
Weissenrieder, JS1
Foskett, JK1
Lee, MS2
Han, HJ1
Choi, TI1
Lee, KH1
Baasankhuu, A1
Kim, HT1
Kim, CH1
Redd, PS1
Payero, L1
Gilbert, DM1
Page, CA1
King, R1
McAssey, EV1
Bodie, D1
Diaz, S1
Hancock, CN1
Lee, HS1
Jung, S1
Lee, SW1
Kim, YT1
Lee, J1
Ren, T1
Yu, Z1
Yu, H1
Deng, K1
Wang, Z1
Li, X1
Wang, H1
Wang, L2
Xu, Y1
Lascano, J1
Riley, L1
Khodayari, N1
Brantly, M1
Gupta, R1
Pradhan, J1
Haldar, A1
Murapaka, C1
Chandra Mondal, P1
Gao, R1
Dai, TY1
Meng, Z1
Sun, XF1
Liu, DX1
Shi, MM1
Li, HR1
Kang, X1
Bi, B1
Zhang, YT1
Xu, TW1
Yan, JM1
Jiang, Q1
Helmchen, G1
Guo, H1
Xiang, W1
Fang, Y1
Li, J4
Lin, Y1
An, X1
Jiang, D1
Cao, Q1
Xu, F1
Shiigi, H1
Wang, W1
Chen, Z1
Akosman, I1
Kumar, N1
Mortenson, R1
Lans, A1
De La Garza Ramos, R1
Eleswarapu, A1
Yassari, R1
Fourman, MS1
Jana, S1
Evans, EGB1
Jang, HS1
Zhang, S2
Zhang, H1
Rajca, A1
Gordon, SE1
Zagotta, WN1
Stoll, S1
Mehl, RA1
Miller, S1
Lee, DA1
Muhimpundu, S1
Maxwell, CA1
Liu, Z1
Shen, F1
Tong, Q1
Tang, M1
Peng, M1
Jiao, Z1
Jiang, Y1
Ao, L1
Fu, W1
Lv, X1
Jiang, G1
Hou, L1
Tu, WC1
McManamen, AM1
Su, X1
Jeacopello, I1
Takezawa, MG1
Hieber, DL1
Hassan, GW1
Lee, UN1
Anana, EV1
Locknane, MP1
Stephenson, MW1
Shinkawa, VAM1
Wald, ER1
DeMuri, GP1
Adams, KN1
Berthier, E1
Thongpang, S1
Theberge, AB1
Jiang, L1
Li, Z1
Dong, Q1
Rong, X1
Dong, G1
Huang, J1
Liang, Y1
Sun, S1
Zhang, R1
Miao, Z1
Senju, C1
Nakazawa, Y1
Oso, T1
Shimada, M1
Kato, K1
Matsuse, M1
Tsujimoto, M1
Masaki, T1
Miyazaki, Y1
Fukushima, S1
Tateishi, S1
Utani, A1
Murota, H1
Tanaka, K1
Mitsutake, N1
Moriwaki, S1
Nishigori, C1
Ogi, T1
Liu, C1
Zhang, X1
Wang, B1
Luo, Z1
Qian, D1
Liu, J1
Waterhouse, GIN1
Barbosa, M1
Marques-Sá, J1
Carvalho, C1
Fernandes, V1
Grilli, D1
Smetana, V1
Ahmed, SJ1
Shtender, V1
Pani, M1
Manfrinetti, P1
Mudring, AV1
Kuang, Y1
Yang, D1
Gai, S1
He, F1
An, B1
Yang, P1
Notini, L1
Schulz, K1
Kubeneck, LJ1
Grigg, ARC1
Rothwell, KA1
Fantappiè, G1
ThomasArrigo, LK1
Kretzschmar, R1
Siswanto, FM1
Okukawa, K1
Tamura, A1
Oguro, A1
Imaoka, S1
Kim, CG1
Jung, M1
Kim, HS1
Lee, CK1
Jeung, HC1
Koo, DH1
Bae, WK1
Zang, DY1
Kim, BJ1
Kim, H1
Yun, UJ1
Che, J1
Park, S1
Kim, TS1
Kwon, WS1
Park, J1
Cho, SW1
Nam, CM1
Chung, HC1
Rha, SY1
Colombo, N1
Van Gorp, T1
Matulonis, UA1
Oaknin, A1
Grisham, RN1
Fleming, GF1
Olawaiye, AB1
Nguyen, DD1
Greenstein, AE1
Custodio, JM1
Pashova, HI1
Tudor, IC1
Lorusso, D1
Zhou, F1
Jiang, Z1
Liang, H1
Ru, S1
Bettiol, AA1
Gao, W1
Lipsyc-Sharf, M1
Jain, E1
Collins, LC1
Rosenberg, SM1
Ruddy, KJ1
Tamimi, RM1
Schapira, L1
Come, SE1
Peppercorn, JM1
Borges, VF1
Warner, E1
Snow, C1
Krop, IE1
Kim, D1
Weiss, J1
Zanudo, JGT1
Partridge, AH1
Wagle, N1
Waks, AG1
Moskowitz, A1
Berg, KM1
Grossestreuer, AV1
Balaji, L1
Liu, X1
Cocchi, MN1
Chase, M1
Gong, MN1
Gong, J1
Parikh, SM1
Ngo, L1
Berlin, N1
Donnino, MW1
Zhou, Y1
Chen, Q1
Zhong, S1
Liu, H1
Koh, K1
Chen, H1
He, J1
Chen, J1
Liu, S1
Lin, L1
Zhang, Y1
Xiao, S1
Cao, S1
Yan, B2
Deng, J1
Gu, J1
Tao, Y1
Huang, C1
Lai, C1
Yong, Q1
Shen, Y1
Gong, Z1
Cao, J1
Mao, W1
Yao, Y1
Zhao, J1
Li, Q1
Liu, K1
Liu, B1
Feng, S1
Chandran, V1
Kunjan, C1
Veerapandian, V1
Kannan, R1
Zhang, T1
von Gunten, U1
Caruso, FR1
Goulart, CDL1
Jr, JCB1
de Oliveira, CR1
Mendes, RG1
Arena, R1
Borghi-Silva, A1
Carrasco-Nuñes, N1
Romano, M1
Cabeza, M1
Jiang, B1
Chen, D1
Zhao, C1
Ma, Y1
Yang, W1
Shen, X1
Satheeshkumar, K1
Saravanakumar, P1
Kalavathi, A1
Vennila, KN1
Elango, KP1
Mues Genannt Koers, L1
Prevost, D1
Paulssen, E1
Hoehr, C1
Ulhassan, Z1
Yang, S1
He, D1
Khan, AR1
Salam, A1
Azhar, W1
Muhammad, S1
Ali, S1
Hamid, Y1
Khan, I1
Sheteiwy, MS1
Zhou, W1
Wang, X1
Xie, Q1
Wang, Y1
Lü, H1
Fu, M1
Wang, D1
Shin, TG1
Kim, WY1
Jo, YH1
Hwang, YJ1
Choi, SH1
Lim, T1
Han, KS1
Shin, J1
Suh, GJ1
Kim, KS1
Kang, GH1
Chapalain, X1
Huet, O1
Balzer, T1
Delbove, A1
Martino, F1
Jacquier, S1
Egreteau, PY1
Darreau, C1
Saint-Martin, M1
Lerolle, N1
Aubron, C1
Stenson, EK2
Cvijanovich, NZ2
Anas, N2
Allen, GL2
Thomas, NJ2
Bigham, MT2
Weiss, SL2
Fitzgerald, JC2
Checchia, PA1
Meyer, K2
Quasney, M2
Hall, M2
Gedeit, R2
Freishtat, RJ2
Nowak, J2
Raj, SS1
Gertz, S2
Grunwell, JR2
Wong, HR2
Jain, PN1
Lutfi, R1
Guirgis, FW1
Williams, DJ1
Hale, M1
Bajwa, AA1
Shujaat, A1
Patel, N1
Kalynych, CJ1
Jones, AE1
Wears, RL1
Dodani, S1
Quinten, VM1
van Meurs, M1
Ter Maaten, JC1
Ligtenberg, JJ1
Mallat, J1
Michel, D1
Salaun, P1
Thevenin, D1
Tronchon, L1
Uchino, S1
Cole, L1
Morimatsu, H2
Goldsmith, D1
Ronco, C1
Bellomo, R1
Kellum, JA1
Song, M1
Almasri, E1
O'Dell, E1
Tibby, SM2
Durward, A2
Murdoch, IA2
Shires, GT2
Peitzman, AB1
Illner, H1
Pittner, RA1
Spitzer, JA1
Mirza, BI1
Sahani, M1
Leehey, DJ1
Patel, SB1
Yang, VL1
Ing, TS1
Skellett, S1
Mayer, A1
Gibson, WH1
Cook, JJ1
Gatipon, G1
Moses, ME1
Karlen, JR1
Piver, MS1
Snyder, SL1
Walker, RI1
Hauptman, JG1
Tvedten, H1
Flear, CT1
Kurihara, Y1
Takeichi, S1
Csata, S1
Gallays, F1
Toth, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253]Phase 3400 participants (Anticipated)Interventional2015-05-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for chlorine and Endotoxin Shock

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Sexuality research & social policy : journal of NSRC : SR & SP, 2023, Apr-05

    Topics: Acute Kidney Injury; Adult; Aged; Albumins; Alloys; Amides; Amino Acids; Animals; Antineoplastic Com

2023
Defining metabolic acidosis in patients with septic shock using Stewart approach.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:3

    Topics: Acid-Base Equilibrium; Acidosis; Aged; Anions; Blood Gas Analysis; Chlorides; Female; Humans; Intens

2012
Solute mass balance during isovolaemic high volume haemofiltration.
    Intensive care medicine, 2003, Volume: 29, Issue:9

    Topics: Adult; Aged; Blood Glucose; Calcium; Carbon Dioxide; Chlorides; Creatinine; Cross-Over Studies; Elec

2003

Other Studies

21 other studies available for chlorine and Endotoxin Shock

ArticleYear
[Extreme electrolyte depletion associated with septic shock as a form of presentation of cystic fibrosis].
    Andes pediatrica : revista Chilena de pediatria, 2022, Volume: 93, Issue:1

    Topics: Alkalosis; Child; Chlorides; Cystic Fibrosis; Humans; Hyponatremia; Infant; Infant, Newborn; Male; S

2022
Hypochloraemia is associated with 28-day mortality in patients with septic shock: a retrospective analysis of a multicentre prospective registry.
    Emergency medicine journal : EMJ, 2021, Volume: 38, Issue:6

    Topics: Aged; Albumins; Biomarkers; Chlorides; Emergency Service, Hospital; Female; Humans; Lactates; Male;

2021
Does Chloride Intake at the Early Phase of Septic Shock Resuscitation Impact on Renal Outcome?
    Shock (Augusta, Ga.), 2021, 09-01, Volume: 56, Issue:3

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Chlorides; Critical Care; Female; Fluid Therapy; Hospi

2021
Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2018, Volume: 19, Issue:2

    Topics: Child; Child, Preschool; Chlorides; Critical Illness; Female; Humans; Infant; Intensive Care Units,

2018
Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock.
    Intensive care medicine, 2018, Volume: 44, Issue:11

    Topics: Acute Kidney Injury; Child; Chlorides; Databases, Factual; Humans; Intensive Care Units; Retrospecti

2018
The relationship of intravenous fluid chloride content to kidney function in patients with severe sepsis or septic shock.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:3

    Topics: Acute Kidney Injury; Aged; Chlorides; Creatinine; Female; Fluid Therapy; Humans; Length of Stay; Lin

2015
Trends in vital signs and routine biomarkers in patients with sepsis during resuscitation in the emergency department: a prospective observational pilot study.
    BMJ open, 2016, 05-25, Volume: 6, Issue:5

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflam

2016
Hyperchloremic acidosis increases circulating inflammatory molecules in experimental sepsis.
    Chest, 2006, Volume: 130, Issue:4

    Topics: Acid-Base Equilibrium; Acidosis; Animals; Blood Pressure; Chlorides; Enzyme-Linked Immunosorbent Ass

2006
Hyperchloremia is the dominant cause of metabolic acidosis in the postresuscitation phase of pediatric meningococcal sepsis.
    Critical care medicine, 2007, Volume: 35, Issue:10

    Topics: Acidosis; Child, Preschool; Chlorides; Cohort Studies; Fluid Therapy; Humans; Infant; Meningococcal

2007
Stewart has come to the bedside: is it time to use the Stewart methodology routinely?
    Critical care medicine, 2007, Volume: 35, Issue:10

    Topics: Acidosis; Chlorides; Fluid Therapy; Humans; Mathematics; Resuscitation; Shock, Septic

2007
Changes in red blood cell transmembrane potential, electrolytes, and energy content in septic shock.
    The Journal of trauma, 1983, Volume: 23, Issue:9

    Topics: Animals; Biological Transport, Active; Cell Membrane Permeability; Chlorides; Disease Models, Animal

1983
Shift from alpha- to beta-type adrenergic receptor-mediated responses in chronically endotoxemic rats.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Angiotensin II; Animals; Cells, Cultured; Chlorides; Endotoxins; Escherichia coli; Glucagon; Inosito

1993
Saline-induced dilutional acidosis in a maintenance hemodialysis patient.
    The International journal of artificial organs, 1999, Volume: 22, Issue:10

    Topics: Acidosis; Aged; Chlorides; Fluid Therapy; Hemodilution; Humans; Kidney Failure, Chronic; Male; Renal

1999
Chasing the base deficit: hyperchloraemic acidosis following 0.9% saline fluid resuscitation.
    Archives of disease in childhood, 2000, Volume: 83, Issue:6

    Topics: Acidosis; Adolescent; Child; Child, Preschool; Chlorides; Fluid Therapy; Humans; Shock, Septic; Sodi

2000
Effect of endotoxin shock on skeletal muscle cell membrane potential.
    Surgery, 1977, Volume: 81, Issue:5

    Topics: Animals; Chlorides; Dogs; Gallamine Triethiodide; Hydrogen-Ion Concentration; Membrane Potentials; M

1977
Reduction of mortality and morbidity associated with pelvic exenteration.
    Gynecologic oncology, 1975, Volume: 3, Issue:2

    Topics: Acidosis; Adolescent; Adult; Aged; Arteries; Chlorides; Hemorrhage; Humans; Infant; Ligation; Liver

1975
Inhibition of lethality in endotoxin-challenged mice treated with zinc chloride.
    Infection and immunity, 1976, Volume: 13, Issue:3

    Topics: Animals; Chlorides; Lipopolysaccharides; Male; Mice; Salmonella typhi; Shock, Septic; Zinc

1976
Osmolal and anion gaps in dogs with acute endotoxic shock.
    American journal of veterinary research, 1986, Volume: 47, Issue:7

    Topics: Animals; Anions; Carbon Dioxide; Chlorides; Dogs; Female; Hydrogen-Ion Concentration; Lactates; Male

1986
Electrolyte and body water changes after trauma.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1970, Volume: 4

    Topics: Animals; Biological Transport, Active; Biopsy; Body Water; Cell Membrane Permeability; Chlorides; Do

1970
[Very rare cardiac arrest due to succinylcholine chloride shock--a successfully treated case].
    Nihon Ishikai zasshi. Journal of the Japan Medical Association, 1970, Mar-01, Volume: 63, Issue:5

    Topics: Adult; Amputation, Surgical; Chlorides; Heart Arrest; Heart Massage; Humans; Leg; Male; Shock, Septi

1970
[Acute renal failure caused by zinc chloride poisoning].
    Zeitschrift fur Urologie und Nephrologie, 1968, Volume: 61, Issue:5

    Topics: Acute Kidney Injury; Adult; Anuria; Chlorides; Humans; Male; Renal Dialysis; Shock, Septic; Suicide;

1968