Page last updated: 2024-10-17

chlorine and Encephalopathy, Toxic

chlorine has been researched along with Encephalopathy, Toxic in 34 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Research Excerpts

ExcerptRelevanceReference
"Aluminum chloride treatment significantly caused cognitive dysfunction and mitochondria oxidative damage as compared to vehicle treated control group."2.78Naringin protects memory impairment and mitochondrial oxidative damage against aluminum-induced neurotoxicity in rats. ( Kumar, A; Prakash, A; Shur, B, 2013)
"Carveol has been researched as an antioxidant and Nrf2-activator in several studies."1.72Carveol ameliorates mercury-induced oxidative stress, neuroinflammation, and neurodegeneration in a mouse brain. ( Alattar, A; Alshaman, R; Alvi, AM; Gul, M; Hussain, N; Ikram, M; Khalil, AAK; Li, J; Li, S; Rashid, S; Shah, FA, 2022)
"L-Theanine is an amino acid derivative primarily found in tea."1.42Protective effect of L-Theanine against aluminium induced neurotoxicity in cerebral cortex, hippocampus and cerebellum of rat brain - histopathological, and biochemical approach. ( Shobana, C; Sumathi, T; Thangarajeswari, M; Usha, R, 2015)
" Chronic use of buffered aspirins, as aspegic, would likely constitute the major human aluminium uptake source."1.42Effect of lysine acetylsalicylate on aluminium accumulation and (Na(+)/K(+))ATPase activity in rat brain cortex synaptosomes after aluminium ingestion. ( Gonçalves, PP; Silva, VS, 2015)
"Melatonin pretreatment of the AlCl3 -administered rats reduced brain damage, and the tissues appeared like those of the control rats."1.42The protective properties of melatonin against aluminium-induced neuronal injury. ( Abdel Moneim, AE; Al-Olayan, EM; El-Khadragy, MF, 2015)
"Mangiferin is a phytochemical primarily present in the stem, leaves and bark of Mangifera indica."1.42Mangiferin ameliorates aluminium chloride-induced cognitive dysfunction via alleviation of hippocampal oxido-nitrosative stress, proinflammatory cytokines and acetylcholinesterase level. ( Jangra, A; Kasbe, P; Lahkar, M, 2015)
"Celecoxib treatment improved social affiliation in the AlCl3‑induced neurotoxicity group, the results of which were superior to piroxicam."1.42Cyclooxygenase I and II inhibitors distinctly enhance hippocampal- and cortex-dependent cognitive functions in mice. ( Ahmed, T; Ikram, MF; Syed, H; Yaqinuddin, A, 2015)
" Moreover, exposure to high Mn levels is known to cause adverse neurological effects in humans, which are yet mechanistically not well understood."1.39Molecular mechanisms of Mn induced neurotoxicity: RONS generation, genotoxicity, and DNA-damage response. ( Beneke, S; Böker, C; Bornhorst, J; Bürkle, A; Mangerich, A; Marschall, T; Meyer, S; Schwerdtle, T; Weber, T, 2013)
"Manganese (Mn) is an essential element and it acts as a cofactor for a number of enzymatic reactions, including those involved in amino acid, lipid, protein, and carbohydrate metabolism."1.38Manganese alters rat brain amino acids levels. ( Almeida, I; Aschner, M; Batoreu, MC; Marreilha dos Santos, AP; Ramos, R; Santos, D; Sidoryk-Wegrzynowicz, M, 2012)
" Our stereological and histopathological findings show that low-dose BA, as a proteasome inhibitor, can decrease the adverse effects of AlCl(3) on the cerebral cortex."1.37The neuroprotective role of boric acid on aluminum chloride-induced neurotoxicity. ( Colak, S; Geyikoglu, F; Keles, ON; Topal, A; Türkez, H; Unal, B, 2011)
"Aluminium, is a trace element available in the Earth's crust naturally and has a toxic potential for humans."1.37Neuroprotective effect of carvedilol against aluminium induced toxicity: possible behavioral and biochemical alterations in rats. ( Dogra, S; Kumar, A; Prakash, A, 2011)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (11.76)29.6817
2010's28 (82.35)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Han, M1
Böhlke, M1
Maher, T1
Kim, J1
Alattar, A1
Alvi, AM1
Rashid, S1
Hussain, N1
Gul, M1
Ikram, M1
Khalil, AAK1
Alshaman, R1
Shah, FA1
Li, S1
Li, J1
Yoshida, K1
Gi, M1
Fujioka, M1
Teramoto, I1
Wanibuchi, H1
Said, MM1
Rabo, MM1
Yan, D1
Jin, C1
Cao, Y2
Wang, L1
Lu, X1
Yang, J1
Wu, S2
Cai, Y1
El-Hady, WM1
Galal, AAA1
Nkpaa, KW1
Amadi, BA1
Wegwu, MO1
Farombi, EO1
Sudhakaran, S1
Athira, SS1
Mohanan, PV1
Jelenković, A1
Jovanović, MD1
Stevanović, I1
Petronijević, N1
Bokonjić, D1
Zivković, J1
Igić, R1
Bornhorst, J1
Meyer, S1
Weber, T1
Böker, C1
Marschall, T1
Mangerich, A1
Beneke, S1
Bürkle, A1
Schwerdtle, T1
Prakash, A2
Shur, B1
Kumar, A2
Sumathi, T1
Shobana, C1
Thangarajeswari, M1
Usha, R1
Yang, W1
Shi, L1
Chen, L1
Zhang, B1
Ma, K1
Liu, Y1
Qian, Y1
Silva, VS1
Gonçalves, PP1
Al-Olayan, EM1
El-Khadragy, MF1
Abdel Moneim, AE2
Singh, T1
Goel, RK1
Kasbe, P1
Jangra, A1
Lahkar, M1
Syed, H1
Ikram, MF1
Yaqinuddin, A1
Ahmed, T1
Abdel-Zaher, AO1
Hamdy, MM1
Abdel-Rahman, MS1
Abd El-Hamid, DH1
Chtourou, Y1
Fetoui, H1
Sefi, M1
Trabelsi, K1
Barkallah, M1
Boudawara, T1
Kallel, H1
Zeghal, N1
Cai, T1
Che, H1
Yao, T1
Chen, Y1
Huang, C1
Zhang, W1
Du, K1
Zhang, J1
Chen, J1
Luo, W1
Li, H1
Shi, N1
Lin, W1
You, J1
Zhou, W1
Shati, AA1
Elsaid, FG1
Hafez, EE1
Colak, S1
Geyikoglu, F1
Keles, ON1
Türkez, H1
Topal, A1
Unal, B1
Thirunavukkarasu, SV1
Venkataraman, S1
Raja, S1
Upadhyay, L1
Dogra, S1
Lebda, MA1
El-Neweshy, MS1
El-Sayed, YS1
Santos, D1
Batoreu, MC1
Almeida, I1
Ramos, R1
Sidoryk-Wegrzynowicz, M1
Aschner, M1
Marreilha dos Santos, AP1
Jovanova-Nesic, K1
Shoenfeld, Y1
Spector, NH1
Robe, PA1
Sadzot, B1
Frank, G1
Jyoti, A1
Sethi, P1
Sharma, D1
Girard, P1
Verniers, D1
Pansart, Y1
Gillardin, JM1
Bostanci, MO1
Bağirici, F1

Reviews

1 review available for chlorine and Encephalopathy, Toxic

ArticleYear
Aluminum excytotoxicity and neuroautotoimmunity: the role of the brain expression of CD32+ (FcγRIIa), ICAM-1+ and CD3ξ in aging.
    Current aging science, 2012, Volume: 5, Issue:3

    Topics: Aging; Aluminum Chloride; Aluminum Compounds; Animals; Autoimmunity; Brain; CD3 Complex; Cell Moveme

2012

Trials

1 trial available for chlorine and Encephalopathy, Toxic

ArticleYear
Naringin protects memory impairment and mitochondrial oxidative damage against aluminum-induced neurotoxicity in rats.
    The International journal of neuroscience, 2013, Volume: 123, Issue:9

    Topics: Acetylcholinesterase; Aluminum Chloride; Aluminum Compounds; Analysis of Variance; Animals; Brain; C

2013

Other Studies

32 other studies available for chlorine and Encephalopathy, Toxic

ArticleYear
Alcohol exposure increases manganese accumulation in the brain and exacerbates manganese-induced neurotoxicity in mice.
    Archives of toxicology, 2021, Volume: 95, Issue:12

    Topics: Alcohol Drinking; Animals; Binge Drinking; Brain; Chlorides; Dopamine; Dose-Response Relationship, D

2021
Carveol ameliorates mercury-induced oxidative stress, neuroinflammation, and neurodegeneration in a mouse brain.
    Neurotoxicology, 2022, Volume: 92

    Topics: Animals; Antioxidants; Brain; Chlorides; Cyclohexane Monoterpenes; Cyclooxygenase 2; Hazardous Subst

2022
Long-term administration of excess zinc impairs learning and memory in aged mice.
    The Journal of toxicological sciences, 2019, Volume: 44, Issue:10

    Topics: Aging; Animals; Avoidance Learning; Chlorides; Female; Hippocampus; Maze Learning; Memory; Mice; Mic

2019
Neuroprotective effects of eugenol against aluminiuminduced toxicity in the rat brain.
    Arhiv za higijenu rada i toksikologiju, 2017, Mar-01, Volume: 68, Issue:1

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Chlorides; Disease Models, Animal; Eug

2017
Effects of Aluminium on Long-Term Memory in Rats and on SIRT1 Mediating the Transcription of CREB-Dependent Gene in Hippocampus.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 121, Issue:4

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor;

2017
Neurotoxic Outcomes of Subchronic Manganese Chloride Exposure via Contaminated Water in Adult Male Rats and the Potential Benefits of Ebselen.
    Biological trace element research, 2018, Volume: 186, Issue:1

    Topics: Administration, Oral; Animals; Antioxidants; Azoles; Chlorides; Dose-Response Relationship, Drug; In

2018
Ethanol increases manganese-Induced spatial learning and memory deficits via oxidative/nitrosative stress induced p53 dependent/independent hippocampal apoptosis.
    Toxicology, 2019, 04-15, Volume: 418

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Behavior, Animal; Chlorides; Disease Models, Anim

2019
Zinc oxide nanoparticle induced neurotoxic potential upon interaction with primary astrocytes.
    Neurotoxicology, 2019, Volume: 73

    Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Caspase 3; Caspase 7; Cell Survival; Cells, Cultur

2019
Influence of the green tea leaf extract on neurotoxicity of aluminium chloride in rats.
    Phytotherapy research : PTR, 2014, Volume: 28, Issue:1

    Topics: Acetylcholinesterase; Aluminum Chloride; Aluminum Compounds; Alzheimer Disease; Animals; Avoidance L

2014
Molecular mechanisms of Mn induced neurotoxicity: RONS generation, genotoxicity, and DNA-damage response.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:7

    Topics: Animals; Astrocytes; Biological Availability; Brain; Cell Line, Tumor; Chlorides; DNA Damage; Food C

2013
Protective effect of L-Theanine against aluminium induced neurotoxicity in cerebral cortex, hippocampus and cerebellum of rat brain - histopathological, and biochemical approach.
    Drug and chemical toxicology, 2015, Volume: 38, Issue:1

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Cerebellum; Cerebral Cortex; Chlorides

2015
Protective effects of perindopril on d-galactose and aluminum trichloride induced neurotoxicity via the apoptosis of mitochondria-mediated intrinsic pathway in the hippocampus of mice.
    Brain research bulletin, 2014, Volume: 109

    Topics: Aluminum Chloride; Aluminum Compounds; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis;

2014
Effect of lysine acetylsalicylate on aluminium accumulation and (Na(+)/K(+))ATPase activity in rat brain cortex synaptosomes after aluminium ingestion.
    Toxicology letters, 2015, Jan-05, Volume: 232, Issue:1

    Topics: Administration, Oral; Aluminum Chloride; Aluminum Compounds; Animals; Aspirin; Cerebral Cortex; Chlo

2015
The protective properties of melatonin against aluminium-induced neuronal injury.
    International journal of experimental pathology, 2015, Volume: 96, Issue:3

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Protei

2015
Neuroprotective effect of Allium cepa L. in aluminium chloride induced neurotoxicity.
    Neurotoxicology, 2015, Volume: 49

    Topics: Acetylcholinesterase; Aluminum Chloride; Aluminum Compounds; Animals; Avoidance Learning; Brain; Cat

2015
Mangiferin ameliorates aluminium chloride-induced cognitive dysfunction via alleviation of hippocampal oxido-nitrosative stress, proinflammatory cytokines and acetylcholinesterase level.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2015, Volume: 31

    Topics: Acetylcholinesterase; Aluminum Chloride; Aluminum Compounds; Animals; Behavior, Animal; Biomarkers;

2015
Cyclooxygenase I and II inhibitors distinctly enhance hippocampal- and cortex-dependent cognitive functions in mice.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Celecoxib; Cerebral Cortex; Chlorides; Cognition; Cy

2015
Protective effect of citicoline against aluminum-induced cognitive impairments in rats.
    Toxicology and industrial health, 2017, Volume: 33, Issue:4

    Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Avoidance Learning; Behavior, Animal; Chlo

2017
Silymarin, a natural antioxidant, protects cerebral cortex against manganese-induced neurotoxicity in adult rats.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2010, Volume: 23, Issue:6

    Topics: Acetylcholinesterase; Animals; Antioxidants; Cells, Cultured; Cerebral Cortex; Chlorides; Glutathion

2010
Manganese induces tau hyperphosphorylation through the activation of ERK MAPK pathway in PC12 cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 119, Issue:1

    Topics: Animals; Cell Culture Techniques; Cell Survival; Chlorides; Enzyme Activation; Extracellular Signal-

2011
NF-E2-related factor 2 activation in PC12 cells: its protective role in manganese-induced damage.
    Archives of toxicology, 2011, Volume: 85, Issue:8

    Topics: Animals; Apoptosis; Chlorides; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; Hydroquino

2011
Biochemical and molecular aspects of aluminium chloride-induced neurotoxicity in mice and the protective role of Crocus sativus L. extraction and honey syrup.
    Neuroscience, 2011, Feb-23, Volume: 175

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Chlorides; Crocus; Disease Models, Ani

2011
The neuroprotective role of boric acid on aluminum chloride-induced neurotoxicity.
    Toxicology and industrial health, 2011, Volume: 27, Issue:8

    Topics: Aluminum Chloride; Aluminum Compounds; Analysis of Variance; Animals; Boric Acids; Brain Diseases; C

2011
Neuroprotective effect of Manasamitra vatakam against aluminium induced cognitive impairment and oxidative damage in the cortex and hippocampus of rat brain.
    Drug and chemical toxicology, 2012, Volume: 35, Issue:1

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Avoidance Learning; Cerebral Cortex; C

2012
Neuroprotective effect of carvedilol against aluminium induced toxicity: possible behavioral and biochemical alterations in rats.
    Pharmacological reports : PR, 2011, Volume: 63, Issue:4

    Topics: Adrenergic beta-Antagonists; Aluminum Chloride; Aluminum Compounds; Animals; Brain; Carbazoles; Carv

2011
Neurohepatic toxicity of subacute manganese chloride exposure and potential chemoprotective effects of lycopene.
    Neurotoxicology, 2012, Volume: 33, Issue:1

    Topics: Acetylcholinesterase; Alkaline Phosphatase; Animals; Antioxidants; Body Weight; Brain; Carotenoids;

2012
Evaluating the potential role of pomegranate peel in aluminum-induced oxidative stress and histopathological alterations in brain of female rats.
    Biological trace element research, 2012, Volume: 150, Issue:1-3

    Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Apoptosis; Apoptosis Regulat

2012
Manganese alters rat brain amino acids levels.
    Biological trace element research, 2012, Volume: 150, Issue:1-3

    Topics: Amino Acids; Animals; Brain; Brain Chemistry; Chlorides; Dose-Response Relationship, Drug; Extrapyra

2012
Sodium bromide encephalopathy with decreased serum Cl- level and increased anion gap: report of one case.
    European neurology, 2004, Volume: 51, Issue:4

    Topics: Acid-Base Imbalance; Adult; Anions; Bromides; Chlorides; Electroencephalography; Humans; Magnetic Re

2004
Bacopa monniera prevents from aluminium neurotoxicity in the cerebral cortex of rat brain.
    Journal of ethnopharmacology, 2007, Apr-20, Volume: 111, Issue:1

    Topics: Aldehydes; Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Bacopa; Cerebral Cortex; Ch

2007
Efficacy of moclobemide in a rat model of neurotoxicant-induced edema.
    Canadian journal of physiology and pharmacology, 2007, Volume: 85, Issue:5

    Topics: Administration, Oral; Animals; Body Mass Index; Brain Edema; Calcium; Cerebral Cortex; Chlorides; Do

2007
Neuroprotective effect of aminoguanidine on iron-induced neurotoxicity.
    Brain research bulletin, 2008, May-15, Volume: 76, Issue:1-2

    Topics: Animals; Chlorides; Enzyme Inhibitors; Ferric Compounds; Guanidines; Hippocampus; Male; Neurons; Neu

2008