Page last updated: 2024-10-17

chlorine and Down Syndrome

chlorine has been researched along with Down Syndrome in 7 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)

Research Excerpts

ExcerptRelevanceReference
"In conclusion, no correlation between dental caries and salivary ionic composition as well as α-amylase secretion rate was found in DS children."1.39Does the chemistry in the saliva of Down syndrome children explain their low caries prevalence? ( Areias, C; de Andrade, C; Leal, I; Macho, V; Melo, P; Sampaio-Maia, B, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Parrini, M1
Naskar, S1
Alberti, M1
Colombi, I1
Morelli, G1
Rocchi, A1
Nanni, M1
Piccardi, F1
Charles, S1
Ronzitti, G1
Mingozzi, F1
Contestabile, A1
Cancedda, L1
Ruf, K1
Demerath, A1
Hebestreit, H1
Kunzmann, S1
Areias, C1
Sampaio-Maia, B1
Macho, V1
Leal, I1
Melo, P1
de Andrade, C1
Davidovich, E1
Aframian, DJ1
Shapira, J1
Peretz, B1
Peng, S1
Rapoport, SI1
Pearce, RJ1
Galdzicki, Z1
Jara, L1
Ondarza, A1
Blanco, R1
Rivera, L1
Milunsky, A1

Other Studies

7 other studies available for chlorine and Down Syndrome

ArticleYear
Restoring neuronal chloride homeostasis with anti-NKCC1 gene therapy rescues cognitive deficits in a mouse model of Down syndrome.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2021, 10-06, Volume: 29, Issue:10

    Topics: Animals; Chlorides; Disease Models, Animal; Down Syndrome; Gene Knockdown Techniques; Genetic Therap

2021
Is sweat testing for cystic fibrosis feasible in patients with down syndrome?
    BMC pulmonary medicine, 2018, Jan-16, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Age Factors; Case-Control Studies; Child; Child, Preschool; Chlorides; Cystic Fib

2018
Does the chemistry in the saliva of Down syndrome children explain their low caries prevalence?
    European journal of paediatric dentistry, 2013, Volume: 14, Issue:1

    Topics: Adolescent; Calcium; Case-Control Studies; Child; Chlorides; Dental Caries; DMF Index; Down Syndrome

2013
A comparison of the sialochemistry, oral pH, and oral health status of Down syndrome children to healthy children.
    International journal of paediatric dentistry, 2010, Volume: 20, Issue:4

    Topics: Adolescent; Calcium; Child; Child, Preschool; Chlorides; Dental Caries; Dental Plaque Index; DMF Ind

2010
Abnormal chloride and potassium conductances in cultured embryonic tongue muscle from trisomy 16 mouse.
    Brain research. Developmental brain research, 2000, Aug-30, Volume: 122, Issue:2

    Topics: Animals; Chlorides; Culture Techniques; Diploidy; Disease Models, Animal; Down Syndrome; Electric Co

2000
Composition of the parotid saliva in Chilean children with Down's syndrome.
    Archivos de biologia y medicina experimentales, 1991, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Bicarbonates; Child; Chile; Chlorides; Dental Caries; Down Syndrome; Electrolytes

1991
Down's syndrome and cystic fibrosis.
    Pediatrics, 1969, Volume: 43, Issue:5

    Topics: Bone Marrow Diseases; Chlorides; Cystic Fibrosis; Down Syndrome; Humans; Infant; Pancreatic Diseases

1969