chlorine has been researched along with Down Syndrome in 7 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In conclusion, no correlation between dental caries and salivary ionic composition as well as α-amylase secretion rate was found in DS children." | 1.39 | Does the chemistry in the saliva of Down syndrome children explain their low caries prevalence? ( Areias, C; de Andrade, C; Leal, I; Macho, V; Melo, P; Sampaio-Maia, B, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Parrini, M | 1 |
| Naskar, S | 1 |
| Alberti, M | 1 |
| Colombi, I | 1 |
| Morelli, G | 1 |
| Rocchi, A | 1 |
| Nanni, M | 1 |
| Piccardi, F | 1 |
| Charles, S | 1 |
| Ronzitti, G | 1 |
| Mingozzi, F | 1 |
| Contestabile, A | 1 |
| Cancedda, L | 1 |
| Ruf, K | 1 |
| Demerath, A | 1 |
| Hebestreit, H | 1 |
| Kunzmann, S | 1 |
| Areias, C | 1 |
| Sampaio-Maia, B | 1 |
| Macho, V | 1 |
| Leal, I | 1 |
| Melo, P | 1 |
| de Andrade, C | 1 |
| Davidovich, E | 1 |
| Aframian, DJ | 1 |
| Shapira, J | 1 |
| Peretz, B | 1 |
| Peng, S | 1 |
| Rapoport, SI | 1 |
| Pearce, RJ | 1 |
| Galdzicki, Z | 1 |
| Jara, L | 1 |
| Ondarza, A | 1 |
| Blanco, R | 1 |
| Rivera, L | 1 |
| Milunsky, A | 1 |
7 other studies available for chlorine and Down Syndrome
| Article | Year |
|---|---|
Restoring neuronal chloride homeostasis with anti-NKCC1 gene therapy rescues cognitive deficits in a mouse model of Down syndrome.
Topics: Animals; Chlorides; Disease Models, Animal; Down Syndrome; Gene Knockdown Techniques; Genetic Therap | 2021 |
Is sweat testing for cystic fibrosis feasible in patients with down syndrome?
Topics: Adolescent; Adult; Age Factors; Case-Control Studies; Child; Child, Preschool; Chlorides; Cystic Fib | 2018 |
Does the chemistry in the saliva of Down syndrome children explain their low caries prevalence?
Topics: Adolescent; Calcium; Case-Control Studies; Child; Chlorides; Dental Caries; DMF Index; Down Syndrome | 2013 |
A comparison of the sialochemistry, oral pH, and oral health status of Down syndrome children to healthy children.
Topics: Adolescent; Calcium; Child; Child, Preschool; Chlorides; Dental Caries; Dental Plaque Index; DMF Ind | 2010 |
Abnormal chloride and potassium conductances in cultured embryonic tongue muscle from trisomy 16 mouse.
Topics: Animals; Chlorides; Culture Techniques; Diploidy; Disease Models, Animal; Down Syndrome; Electric Co | 2000 |
Composition of the parotid saliva in Chilean children with Down's syndrome.
Topics: Adolescent; Adult; Bicarbonates; Child; Chile; Chlorides; Dental Caries; Down Syndrome; Electrolytes | 1991 |
Down's syndrome and cystic fibrosis.
Topics: Bone Marrow Diseases; Chlorides; Cystic Fibrosis; Down Syndrome; Humans; Infant; Pancreatic Diseases | 1969 |