Page last updated: 2024-10-17

chlorine and Deep Vein Thrombosis

chlorine has been researched along with Deep Vein Thrombosis in 33 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Research Excerpts

ExcerptRelevanceReference
"The goal of this study was to develop and validate a new fibrin-targeted imaging agent that enables high-resolution near-infrared fluorescence (NIRF) imaging of deep vein thrombosis (DVT)."7.78Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence. ( Bhayana, B; Hara, T; Jaffer, FA; Kessinger, CW; Khatri, A; Lin, CP; McCarthy, JR; Tearney, GJ; Thompson, B; Weissleder, R, 2012)
"Human obesity is associated with an increased risk for arterial and venous thrombosis and with elevated levels of leptin in the blood."7.72Inhibition of endogenous leptin protects mice from arterial and venous thrombosis. ( Dellas, C; Konstantinides, S; Loskutoff, DJ; Neels, JG; Schäfer, K, 2004)
"AEW significantly reduced thrombus weight."5.62Aqueous extract of Whitmania pigra Whitman ameliorates ferric chloride-induced venous thrombosis in rats via antioxidation. ( Gui, S; Li, P; Lin, B; Tang, P; Wu, Z; Yang, W; Ye, Y; Zhan, Y, 2021)
"Deep vein thrombosis was induced by exposure to ferric chloride or ligation of the infrarenal vena cava of C57BL/6 mice after pretreatment with enoxaparin, ticagrelor or vehicle and in P2Y(12-/-) mice."3.79Contrast ultrasound for the quantification of deep vein thrombosis in living mice: effects of enoxaparin and P2Y12 receptor inhibition. ( Bode, C; Boeynaems, JM; Duerschmied, D; Guenther, F; Hein, L; Herr, N; Idzko, M; Mauler, M; Robaye, B; Roming, F; Von Zur Muhlen, C; Witsch, T, 2013)
"The goal of this study was to develop and validate a new fibrin-targeted imaging agent that enables high-resolution near-infrared fluorescence (NIRF) imaging of deep vein thrombosis (DVT)."3.78Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence. ( Bhayana, B; Hara, T; Jaffer, FA; Kessinger, CW; Khatri, A; Lin, CP; McCarthy, JR; Tearney, GJ; Thompson, B; Weissleder, R, 2012)
"Murine (C57BL/6 mice) models of ferric chloride (FeCl(3))-induced carotid arterial and vena cava thrombosis were established."3.74Lipopolysaccharide augments venous and arterial thrombosis in the mouse. ( Wang, X, 2008)
"To further explore the relationship between FXI and venous thrombosis, we evaluated FXI-deficient and wild-type mice in a ferric chloride (FeCl(3))-induced vena cava thrombosis model."3.73Effects of factor XI deficiency on ferric chloride-induced vena cava thrombosis in mice. ( Gailani, D; Hsu, MY; Ogletree, ML; Schumacher, WA; Seiffert, DA; Smith, PL; Wang, X, 2006)
"Human obesity is associated with an increased risk for arterial and venous thrombosis and with elevated levels of leptin in the blood."3.72Inhibition of endogenous leptin protects mice from arterial and venous thrombosis. ( Dellas, C; Konstantinides, S; Loskutoff, DJ; Neels, JG; Schäfer, K, 2004)
" In three different types of thrombosis models in rats, including stasis and thrombin-induced venous, glass surface-activated arterio-venous shunt, and ferric chloride-induced arterial thrombosis models, CX-397 and rHV-1 elicited potent antithrombotic effects, where the minimum effective doses of rHV-1 tended to be higher than those of CX-397 in the arterio-venous shunt and arterial thrombosis models."3.70Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban. ( Fukazawa, T; Goto, Y; Hayashi, H; Inoue, Y; Komatsu, Y, 1999)
"It can lead to pulmonary embolism with severe respiratory insufficiency and risk of death."2.66By word of mouse: using animal models in venous thrombosis research. ( Brill, A; Campos, J, 2020)
"Mouse models of venous thrombosis contribute to our understanding of the initiation, propagation, and resolution of venous thrombus, as well as allow for the evaluation of new pharmaceutical approaches to prophylaxis and treatment of deep vein thrombosis."2.48Critical review of mouse models of venous thrombosis. ( Diaz, JA; Henke, PK; Mackman, N; Myers, DD; Obi, AT; Wakefield, TW; Wrobleski, SK, 2012)
"AEW significantly reduced thrombus weight."1.62Aqueous extract of Whitmania pigra Whitman ameliorates ferric chloride-induced venous thrombosis in rats via antioxidation. ( Gui, S; Li, P; Lin, B; Tang, P; Wu, Z; Yang, W; Ye, Y; Zhan, Y, 2021)
"Leading experts in venous thrombosis research came together through the American Venous Forum to develop a consensus on maximizing the utility and application of available mouse models of venous thrombosis."1.51Choosing a Mouse Model of Venous Thrombosis. ( Cooley, B; Diaz, JA; Grover, SP; Henke, PK; Lal, BK; Mackman, N; Palmer, OR; Saha, P; Smith, A; Wakefield, TW, 2019)
"In addition, a mouse venous thrombosis model was constructed and treated with miR-126-Exo to clarify the therapeutic effect of miR-126-Exo by histological analysis."1.48Endothelial progenitor cell-derived exosomes, loaded with miR-126, promoted deep vein thrombosis resolution and recanalization. ( Liu, X; Lu, D; Ma, T; Meng, Q; Shen, Z; Sun, J; Yang, J; Yang, Z; Zhang, J; Zhang, Z, 2018)
"Fibrin deposition was significantly greater in VGs of CRP-Tg mice than in WT controls."1.40C-reactive protein induces expression of tissue factor and plasminogen activator inhibitor-1 and promotes fibrin accumulation in vein grafts. ( Fay, WP; Fish, PM; Ji, Y; Lohman, AW; Strawn, TL; Szalai, AJ; Wu, J, 2014)
"Venous thrombosis was induced by electrolytic stimulus to the femoral vein or inferior vena cava ligation."1.39Elevated prothrombin promotes venous, but not arterial, thrombosis in mice. ( Aleman, MM; Byrnes, JR; Cooley, BC; Heisler, MJ; Machlus, KR; Walton, BL; Wang, JG; Wolberg, AS, 2013)
"Animal models studying venous thrombosis are scarce and, in most cases, very crude and rely on sacrificing the animals to excise formed thrombi."1.38In vivo monitoring of venous thrombosis in mice. ( Aghourian, MN; Blostein, MD; Lemarié, CA, 2012)
"Venous thrombosis is augmented by overexpression of the cellular senescence protein p16(INK4a)."1.37Overexpression of the cell cycle inhibitor p16INK4a promotes a prothrombotic phenotype following vascular injury in mice. ( Cardenas, JC; Church, FC; Krishnamurthy, J; Owens, AP; Sharpless, NE; Whinna, HC, 2011)
"Protein infusion of FIX-Triple into haemophilia B mice was not thrombogenic, even at a dose of 13-fold higher than FIX-WT."1.36FIX-Triple, a gain-of-function factor IX variant, improves haemostasis in mouse models without increased risk of thrombosis. ( Kao, CY; Kao, JT; Lin, CN; Lin, SW; Shi, GY; Tao, MH; Wu, HL; Yang, YL; Yu, IS, 2010)
"Dalteparin was used as a reference compound."1.36Evaluation of AR-H067637, the active metabolite of the new direct thrombin inhibitor AZD0837, in models of venous and arterial thrombosis and bleeding in anaesthetised rats. ( Elg, M; Johansson, K; Kjaer, M; Pehrsson, S, 2010)
"This study compared arterial to venous thrombosis in the mutationally analogous Factor V Leiden mouse."1.34Increased venous versus arterial thrombosis in the Factor V Leiden mouse. ( Chen, CY; Cooley, BC; Schmeling, G, 2007)
"Vena cava thrombosis was induced by either oxidative injury to topical FeCl(2) (FeCl(2)-VT) or stenosis-limited blood flow and a hypotonic pressure stress (stasis-VT) in rats."1.34Quantification of platelet composition in experimental venous thrombosis by real-time polymerase chain reaction. ( Hsu, MY; Monticello, TM; Schumacher, WA; Steinbacher, TE; Wang, X, 2007)
" Dose-response studies identified a PCI dose (5 mg kg(-1) bolus plus 5 mg kg(-1) h(-1), i."1.33Murine model of ferric chloride-induced vena cava thrombosis: evidence for effect of potato carboxypeptidase inhibitor. ( Hsu, MY; Ogletree, ML; Schumacher, WA; Smith, PL; Wang, X, 2006)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.03)18.2507
2000's10 (30.30)29.6817
2010's20 (60.61)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Campos, J1
Brill, A1
Li, P1
Lin, B2
Tang, P1
Ye, Y1
Wu, Z1
Gui, S1
Zhan, Y1
Yang, W1
Song, W1
Ci, H1
Tian, G1
Zhang, Y1
Ge, X1
Sun, J1
Zhang, Z2
Ma, T1
Yang, Z1
Zhang, J1
Liu, X1
Lu, D1
Shen, Z1
Yang, J1
Meng, Q1
Diaz, JA2
Saha, P1
Cooley, B1
Palmer, OR1
Grover, SP1
Mackman, N2
Wakefield, TW2
Henke, PK3
Smith, A1
Lal, BK1
Guenther, F1
Herr, N1
Mauler, M1
Witsch, T1
Roming, F1
Hein, L1
Boeynaems, JM1
Robaye, B1
Idzko, M1
Bode, C1
Von Zur Muhlen, C1
Duerschmied, D1
Aleman, MM1
Walton, BL1
Byrnes, JR1
Wang, JG1
Heisler, MJ1
Machlus, KR1
Cooley, BC3
Wolberg, AS1
Zhou, W1
Abdurahman, A1
Umar, A1
Iskander, G1
Abdusalam, E1
Berké, B1
Bégaud, B1
Moore, N1
Ji, Y1
Fish, PM1
Strawn, TL1
Lohman, AW1
Wu, J1
Szalai, AJ1
Fay, WP1
Cui, G1
Shan, L1
Guo, L1
Chu, IK1
Li, G1
Quan, Q1
Zhao, Y1
Chong, CM1
Yu, P1
Hoi, MP1
Sun, Y1
Wang, Y1
Lee, SM1
Xie, H1
Kong, X1
Zhou, H1
Xie, Y1
Sheng, L1
Wang, T1
Xia, L1
Yan, J1
Kao, CY1
Lin, CN1
Yu, IS1
Tao, MH1
Wu, HL1
Shi, GY1
Yang, YL1
Kao, JT1
Lin, SW1
Pehrsson, S1
Johansson, K1
Kjaer, M1
Elg, M1
Cardenas, JC1
Owens, AP1
Krishnamurthy, J1
Sharpless, NE1
Whinna, HC1
Church, FC1
Aghourian, MN1
Lemarié, CA1
Blostein, MD1
Obi, AT1
Myers, DD1
Wrobleski, SK1
Bird, JE2
Smith, PL5
Wang, X7
Schumacher, WA6
Barbera, F2
Revelli, JP1
Seiffert, D1
Huang, C1
Hara, T1
Bhayana, B1
Thompson, B1
Kessinger, CW2
Khatri, A1
McCarthy, JR2
Weissleder, R2
Lin, CP2
Tearney, GJ1
Jaffer, FA2
Joglekar, MV1
Ware, J1
Xu, J1
Fitzgerald, ME1
Gartner, TK1
Crescente, M1
Thomas, GM1
Demers, M1
Voorhees, JR1
Wong, SL1
Ho-Tin-Noé, B1
Wagner, DD1
Ripplinger, CM1
Li, C1
Kim, JW1
Konstantinides, S1
Schäfer, K1
Neels, JG1
Dellas, C1
Loskutoff, DJ1
Röttger, C1
Madlener, K1
Heil, M1
Gerriets, T1
Walberer, M1
Wessels, T1
Bachmann, G1
Kaps, M1
Stolz, E1
Peternel, L1
Drevensek, G1
Cerne, M1
Stalc, A1
Stegnar, M1
Budihna, MV1
Szema, L1
Chen, CY2
Schwab, JP1
Schmeling, G2
Hsu, MY4
Ogletree, ML2
Steinbacher, TE1
Monticello, TM1
Gailani, D1
Seiffert, DA1
Tamasi, JA1
Bird, E1
Komatsu, Y1
Inoue, Y1
Goto, Y1
Fukazawa, T1
Hayashi, H1

Reviews

2 reviews available for chlorine and Deep Vein Thrombosis

ArticleYear
By word of mouse: using animal models in venous thrombosis research.
    Platelets, 2020, May-18, Volume: 31, Issue:4

    Topics: Animals; Chlorides; Constriction, Pathologic; Disease Models, Animal; Femoral Vein; Ferric Compounds

2020
Critical review of mouse models of venous thrombosis.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:3

    Topics: Animals; Chlorides; Constriction; Disease Models, Animal; Electrolysis; Ferric Compounds; Ligation;

2012

Other Studies

31 other studies available for chlorine and Deep Vein Thrombosis

ArticleYear
Aqueous extract of Whitmania pigra Whitman ameliorates ferric chloride-induced venous thrombosis in rats via antioxidation.
    Journal of thrombosis and thrombolysis, 2021, Volume: 52, Issue:1

    Topics: Animals; Antioxidants; Chlorides; Ferric Compounds; Leeches; NF-E2-Related Factor 2; Oxidative Stres

2021
Edoxaban improves venous thrombosis via increasing hydrogen sulfide and homocysteine in rat model.
    Molecular medicine reports, 2017, Volume: 16, Issue:5

    Topics: Animals; Anticoagulants; Chlorides; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Disease

2017
Endothelial progenitor cell-derived exosomes, loaded with miR-126, promoted deep vein thrombosis resolution and recanalization.
    Stem cell research & therapy, 2018, 08-23, Volume: 9, Issue:1

    Topics: Animals; Base Sequence; Bone Marrow Cells; Cadherins; Cell Movement; Cellular Senescence; Chlorides;

2018
Choosing a Mouse Model of Venous Thrombosis.
    Arteriosclerosis, thrombosis, and vascular biology, 2019, Volume: 39, Issue:3

    Topics: Algorithms; Animals; Chlorides; Disease Models, Animal; Electrolysis; Endothelial Cells; Endothelium

2019
Contrast ultrasound for the quantification of deep vein thrombosis in living mice: effects of enoxaparin and P2Y12 receptor inhibition.
    Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:6

    Topics: Adenosine; Animals; Anticoagulants; Chlorides; Contrast Media; Enoxaparin; Ferric Compounds; Male; M

2013
Elevated prothrombin promotes venous, but not arterial, thrombosis in mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:8

    Topics: Animals; Blood Coagulation; Blood Platelets; Carotid Arteries; Chlorides; Disease Models, Animal; Fe

2013
Effects of Cydonia oblonga Miller extracts on blood hemostasis, coagulation and fibrinolysis in mice, and experimental thrombosis in rats.
    Journal of ethnopharmacology, 2014, May-28, Volume: 154, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Coagulation; Cardiovascular Agents; Carotid Artery Thro

2014
C-reactive protein induces expression of tissue factor and plasminogen activator inhibitor-1 and promotes fibrin accumulation in vein grafts.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:10

    Topics: Animals; C-Reactive Protein; Cell Movement; Chlorides; Coronary Artery Bypass; Ferric Compounds; Fib

2014
Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy.
    Scientific reports, 2015, Jun-03, Volume: 5

    Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Chlorides; Disease Models,

2015
TLR4 is involved in the pathogenic effects observed in a murine model of antiphospholipid syndrome.
    Clinical immunology (Orlando, Fla.), 2015, Volume: 160, Issue:2

    Topics: Animals; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; beta 2-Glycoprotein I; Carotid Art

2015
FIX-Triple, a gain-of-function factor IX variant, improves haemostasis in mouse models without increased risk of thrombosis.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:2

    Topics: Animals; Chlorides; Coagulants; Dependovirus; Disease Models, Animal; Dose-Response Relationship, Dr

2010
Evaluation of AR-H067637, the active metabolite of the new direct thrombin inhibitor AZD0837, in models of venous and arterial thrombosis and bleeding in anaesthetised rats.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:6

    Topics: Amidines; Animals; Antithrombin III; Antithrombins; Azetidines; Blood Coagulation; Chlorides; Daltep

2010
Overexpression of the cell cycle inhibitor p16INK4a promotes a prothrombotic phenotype following vascular injury in mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:4

    Topics: Animals; Blood Coagulation; Blood Coagulation Tests; Bone Marrow Transplantation; Chlorides; Cyclin-

2011
In vivo monitoring of venous thrombosis in mice.
    Journal of thrombosis and haemostasis : JTH, 2012, Volume: 10, Issue:3

    Topics: Animals; Anticoagulants; Blood Coagulation; Chlorides; Dalteparin; Disease Models, Animal; Ferric Co

2012
Effects of plasma kallikrein deficiency on haemostasis and thrombosis in mice: murine ortholog of the Fletcher trait.
    Thrombosis and haemostasis, 2012, Volume: 107, Issue:6

    Topics: Animals; Bleeding Time; Chlorides; Disease Models, Animal; Ferric Compounds; Hemorrhage; Hemostasis;

2012
A platelet target for venous thrombosis? P2Y1 deletion or antagonism protects mice from vena cava thrombosis.
    Journal of thrombosis and thrombolysis, 2012, Volume: 34, Issue:2

    Topics: Animals; Blood Platelets; Chlorides; Deoxyadenine Nucleotides; Ferric Compounds; Gene Deletion; Mice

2012
Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence.
    JACC. Cardiovascular imaging, 2012, Volume: 5, Issue:6

    Topics: Animals; Chlorides; Disease Models, Animal; Femoral Vein; Ferric Compounds; Fibrin; Fluorescent Dyes

2012
Platelets, glycoprotein Ib-IX, and von Willebrand factor are required for FeCl(3)-induced occlusive thrombus formation in the inferior vena cava of mice.
    Platelets, 2013, Volume: 24, Issue:3

    Topics: Animals; Blood Platelets; Chlorides; Disease Models, Animal; Ferric Compounds; Mice; Platelet Glycop

2013
ADAMTS13 exerts a thrombolytic effect in microcirculation.
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:3

    Topics: ADAM Proteins; ADAMTS13 Protein; Animals; Chlorides; Computer Systems; Disease Models, Animal; Drug

2012
Inflammation modulates murine venous thrombosis resolution in vivo: assessment by multimodal fluorescence molecular imaging.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:11

    Topics: Animals; Biomarkers; Chlorides; Dextrans; Disease Models, Animal; Femoral Vein; Ferric Compounds; Fl

2012
Inhibition of endogenous leptin protects mice from arterial and venous thrombosis.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:11

    Topics: Animals; Antibodies, Blocking; Arterial Occlusive Diseases; Chlorides; Ferric Compounds; Leptin; Mic

2004
Is heparin treatment the optimal management for cerebral venous thrombosis? Effect of abciximab, recombinant tissue plasminogen activator, and enoxaparin in experimentally induced superior sagittal sinus thrombosis.
    Stroke, 2005, Volume: 36, Issue:4

    Topics: Abciximab; Angiography; Animals; Antibodies, Monoclonal; Anticoagulants; Blood Platelets; Chlorides;

2005
Evaluation of two experimental venous thrombosis models in the rat.
    Thrombosis research, 2005, Volume: 115, Issue:6

    Topics: Animals; Blood Coagulation Tests; Chlorides; Disease Models, Animal; Female; Ferric Compounds; Hemos

2005
A murine model of deep vein thrombosis: characterization and validation in transgenic mice.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:3

    Topics: Animals; Anticoagulants; Chlorides; Coronary Artery Disease; Coronary Vessels; Disease Models, Anima

2005
Murine model of ferric chloride-induced vena cava thrombosis: evidence for effect of potato carboxypeptidase inhibitor.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:2

    Topics: Animals; Carboxypeptidase B2; Carboxypeptidases; Carotid Artery Thrombosis; Chlorides; Disease Model

2006
Increased venous versus arterial thrombosis in the Factor V Leiden mouse.
    Thrombosis research, 2007, Volume: 119, Issue:6

    Topics: Amino Acid Substitution; Animals; Arginine; Arterial Occlusive Diseases; Arteries; Chlorides; Diseas

2007
Quantification of platelet composition in experimental venous thrombosis by real-time polymerase chain reaction.
    Thrombosis research, 2007, Volume: 119, Issue:5

    Topics: Animals; Blood Platelets; Chemokine CCL2; Chlorides; Disease Models, Animal; Ferric Compounds; Gene

2007
Effects of factor XI deficiency on ferric chloride-induced vena cava thrombosis in mice.
    Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:9

    Topics: Animals; Chlorides; Disease Models, Animal; Factor XI Deficiency; Ferric Compounds; Fibrinolysis; Fi

2006
Deficiency in thrombin-activatable fibrinolysis inhibitor (TAFI) protected mice from ferric chloride-induced vena cava thrombosis.
    Journal of thrombosis and thrombolysis, 2007, Volume: 23, Issue:1

    Topics: Animals; Bleeding Time; Carboxypeptidase B2; Carotid Artery Diseases; Chlorides; Coagulants; Disease

2007
Lipopolysaccharide augments venous and arterial thrombosis in the mouse.
    Thrombosis research, 2008, Volume: 123, Issue:2

    Topics: Animals; Arteries; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Dose-Response Relat

2008
Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban.
    Thrombosis and haemostasis, 1999, Volume: 81, Issue:2

    Topics: Amino Acid Sequence; Animals; Arginine; Arterial Occlusive Diseases; Arteriovenous Shunt, Surgical;

1999