Page last updated: 2024-10-17

chlorine and Corneal Diseases

chlorine has been researched along with Corneal Diseases in 4 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Corneal Diseases: Diseases of the cornea.

Research Excerpts

ExcerptRelevanceReference
" One group was given an intraperitoneal injection daily of CPZ HCl, 5 mg/kg for 4 days followed by 4 more days of a daily dosage of 10 mg/kg."1.27Chlorpromazine and lithium interaction: a biochemical and histological study. ( Messiha, FS; Sproat, HF; Striegler, RL, 1983)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Noecker, RJ1
Herrygers, LA1
Anwaruddin, R1
Messiha, FS1
Sproat, HF1
Striegler, RL1
Woods, DE1
Sokol, PA1
Iglewski, BH1
Kempster, AJ1
Larke, JR1
Marsters, JB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of BAK on the Blood Aqueous Barrier of Pseudophakic Patients[NCT01280110]Phase 444 participants (Actual)Interventional2011-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Aqueous Humor Flare

Aqueous humor flare indicates the degree of a break in the blood-aqueous barrier. It is objectively measured with a Laser flare meter. (NCT01280110)
Timeframe: Baseline, 15 days and 30 days.

,
Interventionphotons/msec (Mean)
Baseline15 days30 days
Preservative-free Lubricating Drops9.38.48.4
Preserved (BAK 0.006%) Lubricating Drop8.411.411.9

Macular Thickness

Macular thickness will be measured with an Optical coherence tomography (OCT). Measures 5% under the normal population according to the OCT software will be considered break in the blood-retina barrier. (NCT01280110)
Timeframe: Baseline, 15 days and 30 days.

,
Interventionμm (Mean)
Baseline15 days30 days
Preservative-free Lubricating Drops259.2256.4258.3
Preserved (BAK 0.006%) Lubricating Drop258.5254.9255.9

Other Studies

4 other studies available for chlorine and Corneal Diseases

ArticleYear
Corneal and conjunctival changes caused by commonly used glaucoma medications.
    Cornea, 2004, Volume: 23, Issue:5

    Topics: Animals; Antihypertensive Agents; Benzalkonium Compounds; Chlorides; Conjunctiva; Conjunctival Disea

2004
Chlorpromazine and lithium interaction: a biochemical and histological study.
    Brain research bulletin, 1983, Volume: 11, Issue:2

    Topics: Alcohol Oxidoreductases; Animals; Chlorides; Chlorpromazine; Corneal Diseases; Drug Interactions; Et

1983
Modulatory effect of iron on the pathogenesis of Pseudomonas aeruginosa mouse corneal infections.
    Infection and immunity, 1982, Volume: 35, Issue:2

    Topics: Animals; Bacterial Toxins; Biological Transport; Chlorides; Corneal Diseases; Culture Media; Female;

1982
The effect of hypertonic saline on human corneal hydration.
    The British journal of physiological optics, 1975, Volume: 30, Issue:1

    Topics: Chlorides; Contact Lenses, Hydrophilic; Cornea; Corneal Diseases; Dose-Response Relationship, Drug;

1975