chlorine has been researched along with Brain Injuries in 38 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| " after they had been assigned to one of 8 groups in a 3-way analysis of variance design that involved (1) induction of limbic seizures by a systemic injection of lithium/pilocarpine, (2) physical restraint, and (3) administration of acepromazine." | 7.68 | Extreme hypothermia induced by a synergism of acute limbic seizures, physical restraint, and acepromazine: implications for survival following brain injury. ( Bureau, YR; Persinger, MA, 1993) |
| "Phenytoin treatment prevented the occurrence of convulsive and EEG seizures; however, lipid peroxidation was unaffected (16." | 5.27 | Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy. ( Triggs, WJ; Willmore, LJ, 1984) |
| " after they had been assigned to one of 8 groups in a 3-way analysis of variance design that involved (1) induction of limbic seizures by a systemic injection of lithium/pilocarpine, (2) physical restraint, and (3) administration of acepromazine." | 3.68 | Extreme hypothermia induced by a synergism of acute limbic seizures, physical restraint, and acepromazine: implications for survival following brain injury. ( Bureau, YR; Persinger, MA, 1993) |
| "Amiodarone (AMD) is a powerful antiarrhythmic drug preferred for treatments of tachycardias." | 1.91 | Oxidative Brain Injury Induced by Amiodarone in Rats: Protective Effect of S-methyl Methionine Sulfonium Chloride. ( Turkyilmaz, IB, 2023) |
| "Female LCR rats had less iron-induced brain swelling, smaller lesion volumes, and reduced BBB disruption and HO-1 upregulation compared with male LCR rats." | 1.43 | Effect of Gender on Iron-induced Brain Injury in Low Aerobic Capacity Rats. ( Britton, SL; Du, H; Gao, F; Hua, Y; Keep, RF; Koch, LG; Xi, G; Zheng, M, 2016) |
| "Phenytoin treatment prevented the occurrence of convulsive and EEG seizures; however, lipid peroxidation was unaffected (16." | 1.27 | Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy. ( Triggs, WJ; Willmore, LJ, 1984) |
| "Most studies of clinically relevant cerebral edema emphasize the effect of added tissue fluid in white matter on gross distortion with transtentorial and subfalcine brain herniation." | 1.26 | Biology of glial swelling in experimental brain edema. ( Auen, EL; Barron, KD; Bourke, RS; Kimelberg, HK; Nelson, LR; Popp, AJ; Waldman, JB, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (52.63) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 8 (21.05) | 29.6817 |
| 2010's | 6 (15.79) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Igarashi, K | 1 |
| Iwai, H | 1 |
| Tanaka, KI | 1 |
| Kuwahara, Y | 1 |
| Kitanaka, J | 1 |
| Kitanaka, N | 1 |
| Kurimasa, A | 1 |
| Tomita, K | 1 |
| Sato, T | 1 |
| Turkyilmaz, IB | 1 |
| Ichai, C | 1 |
| Payen, JF | 1 |
| Orban, JC | 1 |
| Quintard, H | 1 |
| Roth, H | 1 |
| Legrand, R | 1 |
| Francony, G | 1 |
| Leverve, XM | 1 |
| Zhao, F | 1 |
| Xi, G | 2 |
| Liu, W | 1 |
| Keep, RF | 2 |
| Hua, Y | 2 |
| Zheng, M | 1 |
| Du, H | 1 |
| Gao, F | 1 |
| Koch, LG | 1 |
| Britton, SL | 1 |
| Martínez-Valverde, T | 1 |
| Sánchez-Guerrero, A | 1 |
| Vidal-Jorge, M | 1 |
| Torné, R | 1 |
| Castro, L | 1 |
| Gandara, D | 1 |
| Munar, F | 2 |
| Poca, MA | 2 |
| Sahuquillo, J | 2 |
| Shulga, A | 1 |
| Thomas-Crusells, J | 1 |
| Sigl, T | 1 |
| Blaesse, A | 1 |
| Mestres, P | 1 |
| Meyer, M | 1 |
| Yan, Q | 1 |
| Kaila, K | 1 |
| Saarma, M | 1 |
| Rivera, C | 1 |
| Giehl, KM | 1 |
| Zhu, L | 1 |
| Wang, HD | 1 |
| Yu, XG | 1 |
| Jin, W | 1 |
| Qiao, L | 1 |
| Lu, TJ | 1 |
| Hu, ZL | 1 |
| Zhou, J | 1 |
| Bourdeaux, C | 1 |
| Brown, J | 1 |
| Gibson, CJ | 1 |
| Meyer, RC | 1 |
| Hamm, RJ | 1 |
| Limbrick, DD | 1 |
| Sombati, S | 1 |
| DeLorenzo, RJ | 1 |
| Makara, JK | 1 |
| Rappert, A | 1 |
| Matthias, K | 1 |
| Steinhäuser, C | 1 |
| Spät, A | 1 |
| Kettenmann, H | 1 |
| COOPER, IS | 1 |
| THOMSEN, AC | 2 |
| ANTHONISEN, P | 1 |
| HILDEN, T | 1 |
| FAGIN, ID | 1 |
| MEHAN, DJ | 1 |
| GASS, HH | 1 |
| CLASEN, RA | 3 |
| COOKE, PM | 1 |
| PANDOLFI, S | 2 |
| CARNECKI, G | 1 |
| BRYAR, G | 1 |
| Yao, Y | 1 |
| Sun, S | 1 |
| Kong, Q | 1 |
| Tong, E | 1 |
| Eisenhut, M | 1 |
| Bonislawski, DP | 1 |
| Schwarzbach, EP | 1 |
| Cohen, AS | 1 |
| Yap, SL | 1 |
| Spector, RG | 1 |
| Willmore, LJ | 2 |
| Rubin, JJ | 1 |
| Triggs, WJ | 1 |
| Bourke, RS | 1 |
| Kimelberg, HK | 2 |
| Nelson, LR | 1 |
| Barron, KD | 2 |
| Auen, EL | 1 |
| Popp, AJ | 1 |
| Waldman, JB | 1 |
| Bureau, YR | 1 |
| Persinger, MA | 1 |
| Hasbani, MJ | 1 |
| Hyrc, KL | 1 |
| Faddis, BT | 1 |
| Romano, C | 1 |
| Goldberg, MP | 1 |
| Ferrer, AM | 1 |
| de Nadal, M | 1 |
| Pedraza, S | 1 |
| Garnacho, A | 1 |
| Rose, JW | 1 |
| Waniewski, RA | 1 |
| Cragoe, EJ | 1 |
| Casey, D | 1 |
| Kvitnitskii-Ryzhov, IuN | 1 |
| Hindo, WA | 1 |
| Rayudu, GV | 1 |
| Ermakova, IA | 1 |
| Burdine, JA | 1 |
| Waltz, TA | 1 |
| Matsen, FA | 1 |
| Rapp, F | 1 |
| Reddy, DR | 1 |
| Prabhakar, V | 1 |
| Rao, BD | 1 |
| Kolb, R | 1 |
| Steinbereithner, K | 1 |
| Mineta, T | 1 |
| Tsutsumi, E | 1 |
| Suzuki, H | 1 |
| Kasai, M | 1 |
| Metzel, E | 1 |
| Zimmermann, WE | 1 |
| Watanabe, T | 1 |
| Fujita, Y | 1 |
| Mitani, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Coagulation Activation in Patients With Intracranial Hypertension After Treatment With Mannitol or Hypertonic Saline Solution.[NCT03409237] | 0 participants (Actual) | Observational | 2020-12-03 | Withdrawn (stopped due to No participant enrolled. The human resources to perform the study also due to the COBID emegency) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for chlorine and Brain Injuries
| Article | Year |
|---|---|
Half-molar sodium lactate infusion to prevent intracranial hypertensive episodes in severe traumatic brain injured patients: a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Body Fluids; Brain Injuries; Chlorides; Double-Blind Method; Female; Humans | 2013 |
Cerebral hemodynamic effects of 7.2% hypertonic saline in patients with head injury and raised intracranial pressure.
Topics: Adult; Aged; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Chlorides; Female; Hemodyn | 2000 |
36 other studies available for chlorine and Brain Injuries
| Article | Year |
|---|---|
Neuroprotective effect of oxytocin on cognitive dysfunction, DNA damage, and intracellular chloride disturbance in young mice after cranial irradiation.
Topics: Animals; Brain Injuries; Chlorides; Cognitive Dysfunction; Cranial Irradiation; DNA Damage; Hippocam | 2022 |
Oxidative Brain Injury Induced by Amiodarone in Rats: Protective Effect of S-methyl Methionine Sulfonium Chloride.
Topics: Amiodarone; Animals; Antioxidants; Brain; Brain Injuries; Chlorides; Glutathione; Oxidative Stress; | 2023 |
Minocycline Attenuates Iron-Induced Brain Injury.
Topics: Albumins; Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Blotting, Western; Brain; Brain Edema | 2016 |
Effect of Gender on Iron-induced Brain Injury in Low Aerobic Capacity Rats.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain Edema; Brain Injuries; Caudate Nucleus; Chlor | 2016 |
Characterization of the Ionic Profile of the Extracellular Space of the Injured and Ischemic Brain: A Microdialysis Study.
Topics: Adolescent; Adult; Brain Injuries; Brain Ischemia; Chlorides; Extracellular Space; Female; Humans; I | 2017 |
Posttraumatic GABA(A)-mediated [Ca2+]i increase is essential for the induction of brain-derived neurotrophic factor-dependent survival of mature central neurons.
Topics: Animals; Animals, Newborn; Axons; Axotomy; Brain Injuries; Brain-Derived Neurotrophic Factor; Bumeta | 2008 |
Erythropoietin prevents zinc accumulation and neuronal death after traumatic brain injury in rat hippocampus: in vitro and in vivo studies.
Topics: Analysis of Variance; Animals; Brain Injuries; Cell Count; Cell Death; Cells, Cultured; Chlorides; D | 2009 |
Sodium bicarbonate lowers intracranial pressure after traumatic brain injury.
Topics: Blood Pressure; Brain Injuries; Catheterization, Central Venous; Cerebrovascular Circulation; Chlori | 2010 |
Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus.
Topics: Animals; Blotting, Western; Brain Injuries; Calcium Channel Blockers; Calcium Signaling; Chlorides; | 2010 |
Calcium influx constitutes the ionic basis for the maintenance of glutamate-induced extended neuronal depolarization associated with hippocampal neuronal death.
Topics: Animals; Animals, Newborn; Brain Injuries; Calcium; Calcium Channel Blockers; Calcium Signaling; Cel | 2003 |
Astrocytes from mouse brain slices express ClC-2-mediated Cl- currents regulated during development and after injury.
Topics: Animals; Astrocytes; Brain; Brain Injuries; Cadmium; Cell Membrane; Cerebral Cortex; Cesium; Chlorid | 2003 |
Disorders of electrolyte metabolism in diseases of the central nervous system.
Topics: Brain; Brain Injuries; Brain Neoplasms; Central Nervous System; Chlorides; Electrolytes; Humans; Sod | 1953 |
[Hyperchloremia and hypernatremia after cranial trauma].
Topics: Blood; Brain; Brain Injuries; Chlorides; Humans; Hypernatremia; Sodium; Water-Electrolyte Imbalance | 1954 |
Electrolyte disturbances in cerebral lesions.
Topics: Blood; Brain; Brain Injuries; Chlorides; Sodium; Sodium, Dietary; Water-Electrolyte Imbalance; Wound | 1954 |
Hyponatremia and hypochloremia as a complication of head injury; report of a case simulating intracranial hematoma.
Topics: Brain; Brain Injuries; Cerebral Hemorrhage; Chlorides; Craniocerebral Trauma; Diagnosis, Differentia | 1958 |
HYPERTONIC UREA IN EXPERIMENTAL CEREBRAL EDEMA.
Topics: Animals; Blood Chemical Analysis; Brain Edema; Brain Injuries; Calcium; Cerebral Hemorrhage; Chlorid | 1965 |
7beta-hydroxycholesterol reduces the extent of reactive gliosis caused by iron deposition in the hippocampus but does not attenuate the iron-induced seizures in rats.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents; Astrocytes; Brain Injuries; Chlorides; Convuls | 2006 |
Re: "Circulating levels of KL-6 in acute respiratory distress syndrome sepsis or traumatic brain injury in critically ill children" by Briassoulis et al. (Pediatr Pulmonol 2006; 41:790-795).
Topics: Adrenergic beta-Agonists; Brain Injuries; Chloride Channels; Chlorides; Cyclic AMP; Cystic Fibrosis | 2006 |
Brain injury impairs dentate gyrus inhibitory efficacy.
Topics: Animals; Blotting, Western; Brain Injuries; Chlorides; Dentate Gyrus; Electrophysiology; Fluorescent | 2007 |
Cerebral composition and function in experimental brain injury in the rat.
Topics: Animals; Autoradiography; Biological Transport, Active; Brain Chemistry; Brain Edema; Brain Injuries | 1967 |
Effects of antiperoxidants on FeCl2-induced lipid peroxidation and focal edema in rat brain.
Topics: Animals; Brain Edema; Brain Injuries; Cerebral Cortex; Chlorides; Ferric Compounds; Iron; Lipid Pero | 1984 |
Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy.
Topics: Animals; Brain Injuries; Chlorides; Electroencephalography; Epilepsy; Ferric Compounds; Lipid Peroxi | 1984 |
Biology of glial swelling in experimental brain edema.
Topics: Animals; Astrocytes; Brain Edema; Brain Injuries; Capillaries; Cats; Cerebral Cortex; Chlorides; Neu | 1980 |
Extreme hypothermia induced by a synergism of acute limbic seizures, physical restraint, and acepromazine: implications for survival following brain injury.
Topics: Acepromazine; Animals; Body Temperature Regulation; Brain Injuries; Chlorides; Hypothermia; Limbic S | 1993 |
Distinct roles for sodium, chloride, and calcium in excitotoxic dendritic injury and recovery.
Topics: Animals; Brain Injuries; Bridged Bicyclo Compounds; Calcium; Cells, Cultured; Chlorides; Coculture T | 1998 |
Astrocytic swelling in traumatic-hypoxic brain injury. Beneficial effects of an inhibitor of anion exchange transport and glutamate uptake in glial cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Astrocytes; Biological Transpor | 1989 |
Reserpine in experimental cerebral edema: further observations.
Topics: Animals; Blood Pressure; Body Temperature; Brain Edema; Brain Injuries; Cerebral Cortex; Cerebral He | 1974 |
[The pathogenesis of edema and swelling of the brain].
Topics: Astrocytes; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Capillary Permeability; Carbon | 1974 |
Technetium in cryogenic cerebral injury and edema.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Brain Neoplasms; Cerebrospinal Fluid Proteins; Cerebrov | 1972 |
[Osmotic shifts in the blood and cerebrospinal fluid of the newborn following asphyxia and intrauterine trauma].
Topics: Acid-Base Equilibrium; Asphyxia Neonatorum; Birth Injuries; Blood; Blood Glucose; Brain Injuries; Ca | 1973 |
Localization of 113mIn-chelates compared with 99mTc-sodium pertechnetate in experimental cerebral lesions.
Topics: Animals; Blood-Brain Barrier; Brain Injuries; Brain Neoplasms; Cerebral Cortex; Chlorides; Cricetina | 1969 |
Tube feeding syndrome (protein intoxication), (a report of three cases).
Topics: Adult; Aged; Brain Injuries; Chlorides; Dehydration; Dietary Proteins; Enteral Nutrition; Humans; Hy | 1971 |
[Comparative studies on the behaviour of CSF- and serum osmolarity under high osmotic load in head and brain injuries].
Topics: Acid-Base Equilibrium; Adolescent; Adult; Amino Acids; Brain Injuries; Cerebrospinal Fluid; Child; C | 1972 |
Clinical and experimental studies on cerebral hypernatremia.
Topics: Adult; Bone and Bones; Brain; Brain Injuries; Brain Neoplasms; Chlorides; Craniocerebral Trauma; Ele | 1971 |
Changes of oxygen pressure, acid-base balance, metabolites and electrolytes in cerebrospinal fluid and blood after cerebral injury.
Topics: Acid-Base Equilibrium; Bicarbonates; Brain; Brain Edema; Brain Injuries; Carbon Dioxide; Chlorides; | 1971 |
[Metabolic alkalosis during convalescence of from head injuries].
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Adult; Alkalosis; Blood Gas Analysis; Brain Injuries; | 1968 |