chlorine has been researched along with Blood Clot in 208 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using ferric chloride-induced carotid artery injury, inferior vena cava ligation model, and platelet function tests, we demonstrated that XN uniquely prevents both venous and arterial thrombosis by inhibiting platelet activation." | 7.85 | Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release. ( Cao, Y; Gu, J; Huang, W; Ji, C; Lee, KH; Li, K; Ma, L; Morris-Natschke, SL; Niu, H; Qin, C; Wei, Z; Wen, L; Xia, Q; Xin, G; Xing, Z; Yeh, JL; Zhang, R; Zheng, H, 2017) |
| "Co-administration of FO and low-dose aspirin may act synergistically to protect against thrombosis and injury-induced vascular remodelling in mice." | 7.81 | Aspirin enhances protective effect of fish oil against thrombosis and injury-induced vascular remodelling. ( Funk, CD; Gong, Y; Li, X; Lin, M; Piao, L; Song, WL; Xiao, B; Yang, F; Yin, H; Yu, Y; Zhang, J; Zhang, Q; Zhu, L, 2015) |
| "The mechanism of action of the widely used in vivo ferric chloride (FeCl3) thrombosis model remains poorly understood; although endothelial cell denudation is historically cited, a recent study refutes this and implicates a role for erythrocytes." | 7.81 | Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach. ( Ciciliano, JC; Dixon, JB; Fay, ME; Gachet, C; Hechler, B; Lam, WA; Li, R; Lyon, LA; Meeks, S; Myers, DR; Sakurai, Y, 2015) |
| "Application of ferric chloride (FeCl(3)) to exposed blood vessels is widely used to initiate thrombosis in laboratory mice." | 7.79 | Red blood cells mediate the onset of thrombosis in the ferric chloride murine model. ( Barr, JD; Chauhan, AK; Hansen, JK; Motto, DG; Schaeffer, GV, 2013) |
| "We evaluate the anti-platelet and anti-thrombotic effects of cilostazol using Multiplate® and PFA-100® in vitro and ex vivo with freshly isolated rat whole blood and in vivo venous and arterial thrombosis models in the same species, in an effort to assess the sensitivity of the whole blood aggregometer assays without potential issues of species differences." | 7.77 | Evaluation of anti-platelet and anti-thrombotic effects of cilostazol with PFA-100® and Multiplate® whole blood aggregometer in vitro, ex vivo and FeCl3-induced thrombosis models in vivo. ( Bae, IH; Chung, JH; Jeong, YS; Kim, CW; Lim, KM; Park, JW; Park, YH; Yun, JW, 2011) |
| "Epidemiologic studies have correlated elevated plasma fibrinogen (hyperfibrinogenemia) with risk of cardiovascular disease and arterial and venous thrombosis." | 7.77 | Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice. ( Cardenas, JC; Church, FC; Machlus, KR; Wolberg, AS, 2011) |
| "The study was performed to investigate, in an animal model of arterial thrombosis in vivo, whether diclofenac differentially influences platelet activation and thrombosis in vessels under non-stimulated conditions or during acute systemic inflammation, such as induced by tumor necrosis factor-alpha (TNF-alpha)." | 7.75 | Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo. ( Buerkle, MA; Hellwig, N; Klauss, V; Krötz, F; Mannell, H; Pircher, J; Pohl, U; Sohn, HY; Struthmann, L, 2009) |
| "The pharmacological properties of YM-254890, a specific G(alpha)q/11 inhibitor, on acute thrombosis and chronic neointima formation after vascular injury have been investigated." | 7.73 | Pharmacological properties of YM-254890, a specific G(alpha)q/11 inhibitor, on thrombosis and neointima formation in mice. ( Hayashi, K; Kawasaki, T; Moritani, Y; Nagai, K; Saito, T; Shigenaga, T; Takamatsu, H; Takasaki, J; Taniguchi, M; Uemura, T, 2005) |
| "Further to characterize the processes involved in the FeCl3-induced thrombosis model, we determined the effect of aspirin, heparin, hirudin, trans-4-(aminomethyl) cyclohexane carboxylic acid (AMCHA), thrombocytopenia, and flow modifications on time to occlusion (TTO) and thrombus weight (TW) in the rat carotid artery." | 7.70 | Demonstration of flow and platelet dependency in a ferric chloride-induced model of thrombosis. ( Kambayashi, J; Lockyer, S, 1999) |
| "AEW significantly reduced thrombus weight." | 5.62 | Aqueous extract of Whitmania pigra Whitman ameliorates ferric chloride-induced venous thrombosis in rats via antioxidation. ( Gui, S; Li, P; Lin, B; Tang, P; Wu, Z; Yang, W; Ye, Y; Zhan, Y, 2021) |
| "Hydrogen sulfide (H2S) is a novel gaseous transmitter, regulating a multitude of biological processes in the cardiovascular and other systems." | 5.43 | Hydrogen sulfide attenuates ferric chloride-induced arterial thrombosis in rats. ( Hu, LF; Li, Q; Liu, CF; Qin, YR; Wang, F; Wang, XH; You, SJ; Zhang, Y, 2016) |
| "Ferric chloride has been widely used to induce arterial thrombosis in a variety of species." | 5.33 | An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research. ( Wang, X; Xu, L, 2005) |
| "Z-335 (0." | 5.31 | Z-335, a new thromboxane A(2) receptor antagonist, prevents arterial thrombosis induced by ferric chloride in rats. ( Kurimoto, T; Sato, R; Tanaka, T, 2000) |
| " Genetic deletion of TSP-1 did not affect platelet activation in vitro, but in vivo models of hemostasis and thrombosis showed that TSP-1-deficient mice had prolonged bleeding, defective thrombosis, and increased sensitivity to the prostacyclin mimetic iloprost." | 4.02 | Thrombospondin-1 promotes hemostasis through modulation of cAMP signaling in blood platelets. ( Aburima, A; Berger, M; Febbraio, M; Naseem, KM; Poole, AW; Spurgeon, BEJ; Webb, BA; Wraith, KS, 2021) |
| " A carotid arterial thrombosis model was induced by ferric chloride in Sprague Dawley rats." | 3.91 | Antithrombotic Effect of Artemisia princeps Pampanini Extracts in Vitro and in FeCl ( Kim, JY; Kim, KJ; Kim, MS; Seok, PR; Shin, JH, 2019) |
| " Troα6/Troα10 displayed prominent inhibitory effect of thrombus formation in fluorescein sodium-induced platelet thrombus formation of mesenteric venules and ferric chloride-induced carotid artery injury thrombosis model without prolonging the in vivo bleeding time." | 3.85 | Trowaglerix Venom Polypeptides As a Novel Antithrombotic Agent by Targeting Immunoglobulin-Like Domains of Glycoprotein VI in Platelet. ( Chang, CH; Chung, CH; Hsu, CC; Huang, TF; Peng, HC; Tsai, CC; Tseng, YJ; Tu, YS, 2017) |
| "Using ferric chloride-induced carotid artery injury, inferior vena cava ligation model, and platelet function tests, we demonstrated that XN uniquely prevents both venous and arterial thrombosis by inhibiting platelet activation." | 3.85 | Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release. ( Cao, Y; Gu, J; Huang, W; Ji, C; Lee, KH; Li, K; Ma, L; Morris-Natschke, SL; Niu, H; Qin, C; Wei, Z; Wen, L; Xia, Q; Xin, G; Xing, Z; Yeh, JL; Zhang, R; Zheng, H, 2017) |
| " In a mouse model of ferric chloride-induced arterial thrombosis, GPVI-CD39 effectively delayed vascular thrombosis but did not increase tail bleeding time in vivo." | 3.85 | ADPase CD39 Fused to Glycoprotein VI-Fc Boosts Local Antithrombotic Effects at Vascular Lesions. ( Adler, K; Borst, O; Brandl, R; Degen, H; Fassbender, J; Gawaz, M; Göbel, S; Jamasbi, J; Lorenz, R; Mojica Munoz, AK; Münch, G; Siess, W; Ungerer, M; Walker, B; Ziegler, M, 2017) |
| "To determine how CD73 activity influences in vivo thrombosis, the time to ferric chloride-induced arterial thrombosis was measured in CD73-null mice." | 3.83 | Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice. ( Chepurko, E; Covarrubias, R; Cowan, PJ; Dwyer, KM; Gumina, RJ; Huttinger, R; Huttinger, ZM; Novitskaya, T; Reynolds, A; Robson, SC; Stanfill, K; Wheeler, DG, 2016) |
| " Finally, the blockade of water entry by acetazolamide attenuated ballooning in vitro and markedly suppressed thrombus formation in vivo in a mouse model of thrombosis." | 3.81 | Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets. ( Agbani, EO; Brown, E; Collins, PW; Cosemans, JM; Heemskerk, JW; Hers, I; Mattheij, NJ; Poole, AW; van den Bosch, MT; Williams, CM, 2015) |
| " In a ferric chloride thrombosis model in vivo, this translated into a defect, under mild injury conditions." | 3.81 | Leukemia-associated Rho guanine-nucleotide exchange factor is not critical for RhoA regulation, yet is important for platelet activation and thrombosis in mice. ( Goggs, R; Harper, MT; Offermanns, S; Poole, AW; Walsh, TG; Williams, CM, 2015) |
| " In vivo, 10 nmol/kg of PZL318 slowed the tumor growth of S180 mice and alleviated the thrombosis of ferric chloride-treated ICR mice, while 100 μmol/kg of PZL318 did not injure healthy mice and they exhibited no liver toxicity." | 3.81 | Small molecule PZL318: forming fluorescent nanoparticles capable of tracing their interactions with cancer cells and activated platelets, slowing tumor growth and inhibiting thrombosis. ( Feng, Q; Li, S; Peng, S; Wang, F; Wang, Y; Wu, J; Wu, W; Zhang, X; Zhao, M; Zhao, S, 2015) |
| "The mechanism of action of the widely used in vivo ferric chloride (FeCl3) thrombosis model remains poorly understood; although endothelial cell denudation is historically cited, a recent study refutes this and implicates a role for erythrocytes." | 3.81 | Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach. ( Ciciliano, JC; Dixon, JB; Fay, ME; Gachet, C; Hechler, B; Lam, WA; Li, R; Lyon, LA; Meeks, S; Myers, DR; Sakurai, Y, 2015) |
| "Co-administration of FO and low-dose aspirin may act synergistically to protect against thrombosis and injury-induced vascular remodelling in mice." | 3.81 | Aspirin enhances protective effect of fish oil against thrombosis and injury-induced vascular remodelling. ( Funk, CD; Gong, Y; Li, X; Lin, M; Piao, L; Song, WL; Xiao, B; Yang, F; Yin, H; Yu, Y; Zhang, J; Zhang, Q; Zhu, L, 2015) |
| "By using a ferric chloride (FeCl3)-induced carotid artery injury thrombosis model, we found time to blood flow cessation was significantly prolonged in Tymp(-/-) and Tymp(+/-) mice compared with wild-type mice." | 3.80 | Thymidine phosphorylase participates in platelet signaling and promotes thrombosis. ( Gigante, A; Hirano, M; Li, W; McIntyre, TM; Perez-Perez, MJ; Silverstein, RL; Yue, H, 2014) |
| " We further analyzed the impact of direct platelet-collagen binding by blocking glycoprotein VI (GPVI) and integrin α2β1 in our ferric chloride murine thrombosis model." | 3.80 | Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation. ( Brown, C; Crawford, B; Danisment, O; Hegadorn, CA; Lillicrap, D; Mewburn, J; Nieswandt, B; Pruss, CM; Rydz, N; Shida, Y; Sponagle, K; Stegner, D; Vidal, B, 2014) |
| " Therefore, the aim of this study was to investigate the effect of Que or DiOHF treatment on platelet function and ferric chloride-induced carotid artery thrombosis in a mouse model of type 1 diabetes." | 3.80 | The flavonols quercetin and 3',4'-dihydroxyflavonol reduce platelet function and delay thrombus formation in a model of type 1 diabetes. ( Jackson, DE; Linden, MD; Mosawy, S; Woodman, OL, 2014) |
| "Deep vein thrombosis was induced by exposure to ferric chloride or ligation of the infrarenal vena cava of C57BL/6 mice after pretreatment with enoxaparin, ticagrelor or vehicle and in P2Y(12-/-) mice." | 3.79 | Contrast ultrasound for the quantification of deep vein thrombosis in living mice: effects of enoxaparin and P2Y12 receptor inhibition. ( Bode, C; Boeynaems, JM; Duerschmied, D; Guenther, F; Hein, L; Herr, N; Idzko, M; Mauler, M; Robaye, B; Roming, F; Von Zur Muhlen, C; Witsch, T, 2013) |
| "Application of ferric chloride (FeCl(3)) to exposed blood vessels is widely used to initiate thrombosis in laboratory mice." | 3.79 | Red blood cells mediate the onset of thrombosis in the ferric chloride murine model. ( Barr, JD; Chauhan, AK; Hansen, JK; Motto, DG; Schaeffer, GV, 2013) |
| " We investigated the thrombolytic effects of saxatilin in mice using a ferric chloride-induced carotid arterial thrombosis model." | 3.79 | Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice. ( Heo, JH; Hong, SY; Kang, S; Kim, YD; Kwon, I; Nam, HS; Yang, SH, 2013) |
| " However, using a ferric chloride-induced arterial thrombosis model, the formation of stable thrombi was significantly impaired, preventing vessel occlusion or leading to recanalization and thromboembolization." | 3.78 | Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10. ( Bachmann, S; Dütting, S; Hagedorn, I; Italiano, JE; Kunert, S; Meyer, I; Nieswandt, B; Schulze, H; Schwiebert, S, 2012) |
| "In this study, we report BF066, a novel adenine derivative, inhibits platelet activation and thrombosis via the adenosine receptor (A(2A)) activation and phosphodiesterase (PDE) inhibition." | 3.78 | BF066, a novel dual target antiplatelet agent without significant bleeding. ( Ding, Z; Du, H; Liu, G; Pan, C; Wei, X; Ye, J; Zhang, S; Zhang, Y, 2012) |
| " A ferric chloride injury model of thrombosis was also evaluated." | 3.78 | Use of a mouse model to elucidate the phenotypic effects of the von Willebrand factor cleavage mutants, Y1605A/M1606A and R1597W. ( Bryant, A; Golder, M; Haberichter, S; Hegadorn, C; Lillicrap, D; Pruss, CM, 2012) |
| "Using recombinant proteins and a murine model, we demonstrated that an ADAMTS13 variant truncated after either the eighth thrombospondin type 1 repeat or the spacer domain inhibits ferric chloride-induced arterial thrombosis in ADAMTS13(-/-) mice with efficacy similar to that of full-length ADAMTS13." | 3.77 | Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis. ( Jin, SY; Sorvillo, N; Voorberg, J; Xiao, J; Xue, J; Zheng, XL, 2011) |
| "We evaluate the anti-platelet and anti-thrombotic effects of cilostazol using Multiplate® and PFA-100® in vitro and ex vivo with freshly isolated rat whole blood and in vivo venous and arterial thrombosis models in the same species, in an effort to assess the sensitivity of the whole blood aggregometer assays without potential issues of species differences." | 3.77 | Evaluation of anti-platelet and anti-thrombotic effects of cilostazol with PFA-100® and Multiplate® whole blood aggregometer in vitro, ex vivo and FeCl3-induced thrombosis models in vivo. ( Bae, IH; Chung, JH; Jeong, YS; Kim, CW; Lim, KM; Park, JW; Park, YH; Yun, JW, 2011) |
| "Epidemiologic studies have correlated elevated plasma fibrinogen (hyperfibrinogenemia) with risk of cardiovascular disease and arterial and venous thrombosis." | 3.77 | Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice. ( Cardenas, JC; Church, FC; Machlus, KR; Wolberg, AS, 2011) |
| "001) and had a shorter time to thrombotic occlusion following ferric chloride injury of the carotid artery (median time to thrombosis of 8 vs." | 3.76 | Enhanced platelet reactivity and thrombosis in Apoe-/- mice exposed to cigarette smoke is attenuated by P2Y12 antagonism. ( Caicedo, J; Dong, A; Gairola, CG; Han, SG; Mueller, P; Saha, S; Smyth, SS, 2010) |
| " Both in vivo thrombus formation in ferric chloride-injured arterioles and thrombocytopenia induced by collagen plus epinephrine challenge were more dramatic in Adamts13(S/S) than in Adamts13(L/L) but less than in Adamts13(-/-)." | 3.75 | The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation. ( Banno, F; Chauhan, AK; Kokame, K; Miyata, S; Miyata, T; Wagner, DD; Yang, J, 2009) |
| "Although nicorandil has a number of beneficial cardiovascular actions, its effects on endothelial cells in the context of thrombosis have not been elucidated." | 3.75 | Nicorandil attenuates FeCl(3)-induced thrombus formation through the inhibition of reactive oxygen species production. ( Eguchi, Y; Higashijima, N; Ishida, H; Ishizuka, N; Kawamura, Y; Takahari, Y; Tamura, N, 2009) |
| "The study was performed to investigate, in an animal model of arterial thrombosis in vivo, whether diclofenac differentially influences platelet activation and thrombosis in vessels under non-stimulated conditions or during acute systemic inflammation, such as induced by tumor necrosis factor-alpha (TNF-alpha)." | 3.75 | Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo. ( Buerkle, MA; Hellwig, N; Klauss, V; Krötz, F; Mannell, H; Pircher, J; Pohl, U; Sohn, HY; Struthmann, L, 2009) |
| " We hypothesized that anti-HSP60 autoantibodies could potentiate thrombosis, and evaluated the effect of anti-murine HSP60 antibodies in a ferric chloride (FeCl3)-induced murine model of carotid artery injury." | 3.75 | Autoantibodies to heat shock protein 60 promote thrombus formation in a murine model of arterial thrombosis. ( Dieudé, M; Gillis, MA; Lajoie, G; Levine, JS; Merhi, Y; Rauch, J; Théorêt, JF; Thorin, E, 2009) |
| " In vivo the most effective molecule (TM5007) inhibits coagulation in 2 models: a rat arteriovenous (AV) shunt model and a mouse model of ferric chloride-induced testicular artery thrombosis." | 3.74 | Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis. ( Hirayama, N; Ishida, H; Izuhara, Y; Kurokawa, K; Miyata, T; Nangaku, M; Takahashi, S; Takizawa, S; van Ypersele de Strihou, C, 2008) |
| " beta(3)(L746A) mice were resistant to both pulmonary thromboembolism and to ferric chloride-induced thrombosis of the carotid artery." | 3.74 | The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation. ( Ablooglu, AJ; Fogelstrand, P; Ginsberg, MH; Partridge, AW; Petrich, BG; Shattil, SJ; Yousefi, N, 2007) |
| "Surgical castration was performed in male rats and ferric chloride (FeCl(3)), as a stimulator, induced the experimental arterial thrombosis." | 3.74 | Experimental arterial thrombosis regulated by androgen and its receptor via modulation of platelet activation. ( Cong, Y; Deng, X; Li, J; Li, S; Li, X; Li, Y, 2007) |
| " After exposure for 10 +/- 1 weeks, arterial thrombosis and neointima formation at the carotid artery were induced using 10% ferric chloride." | 3.74 | Cigarette smoke exposure promotes arterial thrombosis and vessel remodeling after vascular injury in apolipoprotein E-deficient mice. ( Berges, A; Humboldt, T; Konstantinides, S; Lebrun, S; Leifheit, M; Meurrens, K; Sawalich, M; Schaefer, K; Schleef, R; Schroeter, MR; Wallerath, T; Xu, H, 2008) |
| " In vivo effect of CPI was also investigated using ferric chloride-induced arterial thrombosis model in rat." | 3.74 | Antithrombotic effects due to pharmacological modulation of thrombin-activatable fibrinolysis inhibitor in rats. ( Bhatt, S; Jain, MR; Patel, PR; Sharma, A; Soni, H, 2008) |
| "Murine (C57BL/6 mice) models of ferric chloride (FeCl(3))-induced carotid arterial and vena cava thrombosis were established." | 3.74 | Lipopolysaccharide augments venous and arterial thrombosis in the mouse. ( Wang, X, 2008) |
"The overall rank-order of potency in thrombosis models based on per cent of vessels occluded, average carotid blood flow, and thrombus weight was aspirin=argatroban=tirofiban| 3.74 | Prediction of the therapeutic index of marketed anti-coagulants and anti-platelet agents by guinea pig models of thrombosis and hemostasis. ( Allegretto, N; Barbera, F; Bird, JE; Giancarli, MR; Ogletree, ML; Schumacher, WA; Seiffert, D; Wong, P, 2008) | |
| "The pharmacological properties of YM-254890, a specific G(alpha)q/11 inhibitor, on acute thrombosis and chronic neointima formation after vascular injury have been investigated." | 3.73 | Pharmacological properties of YM-254890, a specific G(alpha)q/11 inhibitor, on thrombosis and neointima formation in mice. ( Hayashi, K; Kawasaki, T; Moritani, Y; Nagai, K; Saito, T; Shigenaga, T; Takamatsu, H; Takasaki, J; Taniguchi, M; Uemura, T, 2005) |
| " A ferric chloride model of thrombosis was used to investigate thrombus formation in carotid arteries." | 3.73 | Platelet PECAM-1 inhibits thrombus formation in vivo. ( Barrett, NE; Cooley, B; Falati, S; Furie, B; Furie, BC; Gibbins, JM; Gross, PL; Merrill-Skoloff, G; Newman, DK; Newman, PJ; Patil, S; Pixton, KL; Stapleton, M; Weiler, H, 2006) |
| " In vivo experiments in a ferric-chloride thrombosis model of the mouse carotid artery demonstrate similar antithrombotic potency of activation-specific scFv, when compared with the conformation-unspecific blockers tirofiban and eptifibatide." | 3.73 | Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets. ( Ahrens, I; Bassler, N; Bode, C; Chen, YC; Fitzgerald, D; Hagemeyer, CE; Kenny, D; Meade, G; Moran, N; Peter, K; Schwarz, M; Stoll, P; Ylanne, J, 2006) |
| "The recent observation that knock-out of protease-activated receptor-4 (PAR4) ablates thrombin signaling in mouse platelets and protects against ferric chloride-induced thrombosis of mouse mesenteric arterioles suggests that thrombin's actions on platelets can play an important role in thrombosis." | 3.71 | Protection against thrombosis in mice lacking PAR3. ( Coughlin, SR; Hamilton, JR; Lease, KE; Weiss, EJ, 2002) |
| " Compound 5 is highly selective for thrombin over trypsin, is efficacious in the rat ferric chloride model of arterial thrombosis and is orally bioavailable in dogs and cynomolgus monkeys." | 3.70 | L-374,087, an efficacious, orally bioavailable, pyridinone acetamide thrombin inhibitor. ( Chen, IW; Chen, Z; Cook, JJ; Cutrona, KJ; Dorsey, BD; Dyer, DL; Gardell, SJ; Krueger, JA; Lewis, SD; Lin, JH; Lucas, BJ; Lyle, EA; Lynch, JJ; McDonough, CM; Naylor-Olsen, AM; Sanderson, PE; Shafer, JA; Stranieri, MT; Vacca, JP; Vastag, K, 1998) |
| " In three different types of thrombosis models in rats, including stasis and thrombin-induced venous, glass surface-activated arterio-venous shunt, and ferric chloride-induced arterial thrombosis models, CX-397 and rHV-1 elicited potent antithrombotic effects, where the minimum effective doses of rHV-1 tended to be higher than those of CX-397 in the arterio-venous shunt and arterial thrombosis models." | 3.70 | Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban. ( Fukazawa, T; Goto, Y; Hayashi, H; Inoue, Y; Komatsu, Y, 1999) |
| "Further to characterize the processes involved in the FeCl3-induced thrombosis model, we determined the effect of aspirin, heparin, hirudin, trans-4-(aminomethyl) cyclohexane carboxylic acid (AMCHA), thrombocytopenia, and flow modifications on time to occlusion (TTO) and thrombus weight (TW) in the rat carotid artery." | 3.70 | Demonstration of flow and platelet dependency in a ferric chloride-induced model of thrombosis. ( Kambayashi, J; Lockyer, S, 1999) |
| "Thrombosis is one of the major causes of human death worldwide." | 2.50 | Involvement of neutrophils in thrombus formation in living mice. ( Darbousset, R; Dignat-George, F; Dubois, C; Mezouar, S; Panicot-Dubois, L, 2014) |
| "Mouse models of thrombosis have extended our understanding of the role of tissue factor (TF) in thrombogenesis." | 2.46 | Tissue factor and thrombosis models. ( Gross, PL; Kretz, CA; Vaezzadeh, N, 2010) |
| "To fully characterize thrombus formation in these settings, in vivo models are necessary to study the various components and intricate interactions that are involved." | 2.44 | Murine models of vascular thrombosis (Eitzman series). ( Eitzman, DT; Westrick, RJ; Winn, ME, 2007) |
| "AEW significantly reduced thrombus weight." | 1.62 | Aqueous extract of Whitmania pigra Whitman ameliorates ferric chloride-induced venous thrombosis in rats via antioxidation. ( Gui, S; Li, P; Lin, B; Tang, P; Wu, Z; Yang, W; Ye, Y; Zhan, Y, 2021) |
| "KPI and KPIHSA similarly reduced thrombus size and occlusion in both venous and arterial thrombosis models when administered at the time of injury, but only KPI was effective when administered one hour before injury." | 1.48 | Fusion to Human Serum Albumin Extends the Circulatory Half-Life and Duration of Antithrombotic Action of the Kunitz Protease Inhibitor Domain of Protease Nexin 2. ( Bhakta, V; Eltringham-Smith, LJ; Sheffield, WP, 2018) |
| "Thrombosis is a main cause of acute cardiovascular events, and detecting thrombi in small arteries via noninvasive imaging remains challenging." | 1.46 | Photoacoustic Imaging: A Novel Tool for Detecting Carotid Artery Thrombosis in Mice. ( Fan, Q; Fu, C; Li, B; Ma, G; Yao, Y, 2017) |
| "Hydrogen sulfide (H2S) is a novel gaseous transmitter, regulating a multitude of biological processes in the cardiovascular and other systems." | 1.43 | Hydrogen sulfide attenuates ferric chloride-induced arterial thrombosis in rats. ( Hu, LF; Li, Q; Liu, CF; Qin, YR; Wang, F; Wang, XH; You, SJ; Zhang, Y, 2016) |
| "Platelet adhesion and in vitro thrombus formation under high arterial shear rates (1,700 s(-1)) were significantly augmented in cd44(-/-) mice." | 1.43 | CD44 sensitivity of platelet activation, membrane scrambling and adhesion under high arterial shear rates. ( Alzoubi, K; Borst, O; Chatterjee, M; Chen, H; Elvira, B; Föller, M; Gawaz, M; Lang, F; Liu, G; Luo, D; Mak, TW; Münzer, P; Umbach, AT; Voelkl, J; Walker, B, 2016) |
| " In the dose-response study, a single administration of prasugrel at 0." | 1.42 | Prevention of occlusive arterial thrombus formation by a single loading dose of prasugrel suppresses neointimal hyperplasia in mice. ( Jakubowski, JA; Mizuno, M; Ohno, K; Sugidachi, A; Tomizawa, A, 2015) |
| "In vitro extracellular CyPA enhanced thrombus formation even in CyPA(-/-) platelets." | 1.42 | Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo. ( Borst, O; Chatterjee, M; Fischer, G; Gawaz, M; Heinzmann, D; Lang, F; Langer, H; Mack, AF; Malešević, M; May, AE; Münzer, P; Schmidt, EM; Schönberger, T; Seizer, P; Ungern-Sternberg, SN, 2015) |
| "In vitro thrombus formation at shear rates of 1700 s(-1) and in vivo thrombus formation after FeCl3 injury were significantly blunted in Smpd1(-/-) mice while bleeding time was unaffected." | 1.40 | Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation. ( Borst, O; Chatterjee, M; Cosemans, JM; Elvers, M; Feijge, MA; Ferlinz, K; Gawaz, M; Gulbins, E; Heemskerk, JW; Lang, F; Leibrock, C; May, AE; Münzer, P; Schaller, M; Schmid, E; Schmidt, EM; Schmidt, S; Seizer, P; Towhid, ST; Walker, B, 2014) |
| "Anfibatide also inhibited thrombus growth at low shear conditions, though less than at high shear." | 1.40 | Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis. ( Dai, X; Hou, Y; Lei, X; Li, BX; Liang, C; Marshall, AH; Ni, H; Reheman, A; Vanhoorelbeke, K; Wang, Y; Zhou, H, 2014) |
| "GDF-15(-/-) mice showed an accelerated thrombus formation and a reduced survival rate after collagen-induced pulmonary thromboembolism." | 1.39 | GDF-15 prevents platelet integrin activation and thrombus formation. ( Rossaint, J; Vestweber, D; Zarbock, A, 2013) |
| " Either fucoidan or heparin was dosed at 0." | 1.38 | An antithrombotic fucoidan, unlike heparin, does not prolong bleeding time in a murine arterial thrombosis model: a comparative study of Undaria pinnatifida sporophylls and Fucus vesiculosus. ( Kim, JK; Kwon, OC; Lee, S; Min, SK; Park, KH, 2012) |
| "Thrombosis was generated in murine carotid arteries and femoral veins by brief vascular surface electrolytic injury." | 1.37 | In vivo fluorescence imaging of large-vessel thrombosis in mice. ( Cooley, BC, 2011) |
| "Process of occlusive thrombus growth was continuously visualized by 3-D imaging system equipped with ultra-fast confocal microscopy, and time to vascular occlusion was measured in each mouse." | 1.36 | Possible mechanism of preventive effects of coffee intake on the formation of arterial occlusive thrombosis. ( Aoki, T; Goto, S; Ishida, H; Takahari, Y; Tamura, N; Toda, E; Urano, T, 2010) |
| "Dalteparin was used as a reference compound." | 1.36 | Evaluation of AR-H067637, the active metabolite of the new direct thrombin inhibitor AZD0837, in models of venous and arterial thrombosis and bleeding in anaesthetised rats. ( Elg, M; Johansson, K; Kjaer, M; Pehrsson, S, 2010) |
| "The development and application of animal models of thrombosis have played a crucial role in the discovery and validation of novel drug targets and the selection of new agents for clinical evaluation, and have informed dosing and safety information for clinical trials." | 1.36 | In vivo models for the evaluation of antithrombotics and thrombolytics. ( Mousa, SA, 2010) |
| "Variable thrombocytopenia was observed in mice expressing 2B VWF, mimicking the severity seen in 2B VWD patients: mice expressing the V1316M mutation showed the most severe thrombocytopenia." | 1.36 | Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions. ( Golder, M; Hegadorn, C; Laverty, K; Lillicrap, D; Mewburn, J; Pruss, CM; Sponagle, K, 2010) |
| "Gene therapy for severe von Willebrand disease (vWD) seems an interesting treatment alternative with long-term therapeutic potential." | 1.35 | Restoration of plasma von Willebrand factor deficiency is sufficient to correct thrombus formation after gene therapy for severe von Willebrand disease. ( Chuah, MK; De Meyer, SF; Deckmyn, H; Lenting, PJ; Pareyn, I; Petrus, I; VandenDriessche, T; Vandeputte, N; Vanhoorelbeke, K, 2008) |
| "The degree of arterial damage and the thrombus extension were, however, not significantly different." | 1.35 | Obesity promotes injury induced femoral artery thrombosis in mice. ( Cleuren, AC; Hoylaerts, MF; Lijnen, HR; Nagai, N; Van Vlijmen, BJ, 2008) |
| "Aspirin pre-treatment at the dose tested did not influence either endothelial injury or platelet thrombus growth, while clopidogrel pretreatment significantly inhibited 3D growth and prolonged occlusion time up to 64." | 1.35 | Imaging of structural changes in endothelial cells and thrombus formation at the site of FeCl(3)-induced injuries in mice cremasteric arteries. ( Eguchi, Y; Goto, S; Ishida, H; Kawamura, Y; Takahari, Y; Tamura, N; Urano, T, 2009) |
| "Aspirin treatment of wild-type mice causes similar effects, while the thromboxane A(2) analogue U46619 was borderline effective in suppressing the embolisation in alpha2-null mice." | 1.34 | Role of murine integrin alpha2beta1 in thrombus stabilization and embolization: contribution of thromboxane A2. ( Cosemans, JM; Eckes, B; Heemskerk, JW; Kuijpers, MJ; Munnix, IC; Nieswandt, B; Pozgajova, M, 2007) |
| "This study compared arterial to venous thrombosis in the mutationally analogous Factor V Leiden mouse." | 1.34 | Increased venous versus arterial thrombosis in the Factor V Leiden mouse. ( Chen, CY; Cooley, BC; Schmeling, G, 2007) |
| "Vena cava thrombosis was induced by either oxidative injury to topical FeCl(2) (FeCl(2)-VT) or stenosis-limited blood flow and a hypotonic pressure stress (stasis-VT) in rats." | 1.34 | Quantification of platelet composition in experimental venous thrombosis by real-time polymerase chain reaction. ( Hsu, MY; Monticello, TM; Schumacher, WA; Steinbacher, TE; Wang, X, 2007) |
| "However, neither its role in thrombus formation and cardiovascular disorders nor its suitability as a therapeutic target structure is entirely clear." | 1.34 | Diminished thrombus formation and alleviation of myocardial infarction and reperfusion injury through antibody- or small-molecule-mediated inhibition of selectin-dependent platelet functions. ( Boehncke, WH; Krahn, T; Ludwig, RJ; Nieswandt, B; Oostingh, GJ; Pozgajova, M; Schön, MP, 2007) |
| "Obesity is a major risk factor for development of thrombotic cardiovascular disease." | 1.34 | Factor V Leiden mutation is associated with enhanced arterial thrombotic tendency in lean but not in obese mice. ( Cleuren, AC; Hoylaerts, MF; Lijnen, HR; Nagai, N; Rosendaal, FR; Van Hoef, B; Van Vlijmen, BJ, 2007) |
| "Times to initial thrombus formation and vessel occlusion were delayed in FcRgamma(-/-) compared with wild-type mice after severe injury." | 1.33 | Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo. ( Dubois, C; Furie, B; Furie, BC; Merrill-Skoloff, G; Panicot-Dubois, L, 2006) |
| "Ferric chloride has been widely used to induce arterial thrombosis in a variety of species." | 1.33 | An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research. ( Wang, X; Xu, L, 2005) |
| "The delay in thrombus formation in hemin-treated mice was completely blunted by tin protoporphyrin-IX, a HO-1 inhibitor, but not by copper protoporphyrin-IX, which does not inhibit the enzyme." | 1.32 | Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivo. ( Bordel, R; Lindenblatt, N; Menger, MD; Schareck, W; Vollmar, B, 2004) |
| "Z-335 (0." | 1.31 | Z-335, a new thromboxane A(2) receptor antagonist, prevents arterial thrombosis induced by ferric chloride in rats. ( Kurimoto, T; Sato, R; Tanaka, T, 2000) |
| "Ferric chloride was used to induce carotid artery injury in 97 wild-type (WT), 84 PAI-1-/-, and 84 VN-/- mice." | 1.31 | Plasminogen activator inhibitor-1 and its cofactor vitronectin stabilize arterial thrombi after vascular injury in mice. ( Konstantinides, S; Loskutoff, DJ; Schäfer, K; Thinnes, T, 2001) |
| "Platelet thrombus growth after FeCl(3)-induced acute endothelial injury was accelerated in mutant mice." | 1.31 | Characterization of a mouse model for thrombomodulin deficiency. ( Conway, EM; Cooley, BC; Hendrickson, SB; Isermann, BH; Kerlin, B; Lindner, V; Meh, DA; Mosesson, MW; Post, MJ; Shworak, NW; Ulfman, LH; von Andrian, UH; Weiler, H; Weitz, JI, 2001) |
| "01), and reduced weight of the thrombus (18." | 1.30 | Inhibition of arterial thrombus formation by ApoA1 Milano. ( Khan, S; Li, D; Mehta, JL; Nichols, WW; Saldeen, T; Weng, S; Yang, B; Zander, DS, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (9.62) | 18.7374 |
| 1990's | 7 (3.37) | 18.2507 |
| 2000's | 67 (32.21) | 29.6817 |
| 2010's | 107 (51.44) | 24.3611 |
| 2020's | 7 (3.37) | 2.80 |
| Authors | Studies |
|---|---|
| Sugimoto, T | 1 |
| Yamada, H | 1 |
| Wada, N | 1 |
| Motoyama, S | 1 |
| Saburi, M | 1 |
| Kubota, H | 1 |
| Miyawaki, D | 1 |
| Wakana, N | 1 |
| Kami, D | 1 |
| Ogata, T | 1 |
| Ibi, M | 1 |
| Matoba, S | 1 |
| Gul, H | 1 |
| Jabeen, Q | 1 |
| Al-Horani, RA | 1 |
| Abdelfadiel, EI | 1 |
| Afosah, DK | 1 |
| Morla, S | 1 |
| Sistla, JC | 1 |
| Mohammed, B | 1 |
| Martin, EJ | 1 |
| Sakagami, M | 1 |
| Brophy, DF | 1 |
| Desai, UR | 1 |
| Kim, KJ | 1 |
| Kim, MS | 1 |
| Seok, PR | 1 |
| Shin, JH | 1 |
| Kim, JY | 1 |
| Ye, S | 1 |
| Liu, Y | 3 |
| Lu, Y | 1 |
| Ji, Y | 1 |
| Mei, L | 1 |
| Yang, M | 1 |
| Gong, X | 1 |
| Gu, Q | 1 |
| Li, D | 3 |
| Yang, F | 2 |
| Li, CJ | 1 |
| Wilbs, J | 1 |
| Kong, XD | 1 |
| Middendorp, SJ | 1 |
| Prince, R | 1 |
| Cooke, A | 1 |
| Demarest, CT | 1 |
| Abdelhafez, MM | 1 |
| Roberts, K | 1 |
| Umei, N | 1 |
| Gonschorek, P | 1 |
| Lamers, C | 1 |
| Deyle, K | 1 |
| Rieben, R | 1 |
| Cook, KE | 1 |
| Angelillo-Scherrer, A | 1 |
| Heinis, C | 1 |
| Li, P | 1 |
| Lin, B | 2 |
| Tang, P | 1 |
| Ye, Y | 1 |
| Wu, Z | 1 |
| Gui, S | 1 |
| Zhan, Y | 1 |
| Yang, W | 1 |
| Aburima, A | 1 |
| Berger, M | 1 |
| Spurgeon, BEJ | 1 |
| Webb, BA | 1 |
| Wraith, KS | 1 |
| Febbraio, M | 1 |
| Poole, AW | 3 |
| Naseem, KM | 1 |
| Polak, D | 1 |
| Talar, M | 1 |
| Wolska, N | 1 |
| Wojkowska, DW | 1 |
| Karolczak, K | 1 |
| Kramkowski, K | 2 |
| Bonda, TA | 1 |
| Watala, C | 1 |
| Przygodzki, T | 1 |
| Smith, CW | 1 |
| Thomas, SG | 1 |
| Raslan, Z | 1 |
| Patel, P | 1 |
| Byrne, M | 1 |
| Lordkipanidzé, M | 1 |
| Bem, D | 1 |
| Meyaard, L | 1 |
| Senis, YA | 1 |
| Watson, SP | 1 |
| Mazharian, A | 1 |
| Kang, C | 1 |
| Gwon, S | 1 |
| Song, C | 1 |
| Kang, PM | 1 |
| Park, SC | 1 |
| Jeon, J | 1 |
| Hwang, DW | 1 |
| Lee, D | 1 |
| Martinez de Lizarrondo, S | 1 |
| Gakuba, C | 1 |
| Herbig, BA | 1 |
| Repessé, Y | 1 |
| Ali, C | 1 |
| Denis, CV | 4 |
| Lenting, PJ | 4 |
| Touzé, E | 1 |
| Diamond, SL | 1 |
| Vivien, D | 1 |
| Gauberti, M | 1 |
| Yang, J | 2 |
| Jin, K | 1 |
| Xiao, J | 2 |
| Ma, J | 1 |
| Ma, D | 3 |
| Chang, CH | 1 |
| Chung, CH | 1 |
| Tu, YS | 1 |
| Tsai, CC | 1 |
| Hsu, CC | 2 |
| Peng, HC | 1 |
| Tseng, YJ | 1 |
| Huang, TF | 2 |
| Hu, L | 2 |
| Chang, L | 1 |
| Zhang, Y | 4 |
| Zhai, L | 1 |
| Zhang, S | 4 |
| Qi, Z | 1 |
| Yan, H | 1 |
| Yan, Y | 1 |
| Luo, X | 1 |
| Wang, Y | 8 |
| Kunapuli, SP | 2 |
| Ye, H | 1 |
| Ding, Z | 3 |
| Chrysanthopoulou, A | 1 |
| Kambas, K | 1 |
| Stakos, D | 1 |
| Mitroulis, I | 1 |
| Mitsios, A | 1 |
| Vidali, V | 1 |
| Angelidou, I | 1 |
| Bochenek, M | 1 |
| Arelaki, S | 1 |
| Arampatzioglou, A | 1 |
| Galani, IE | 1 |
| Skendros, P | 1 |
| Couladouros, EA | 1 |
| Konstantinides, S | 4 |
| Andreakos, E | 1 |
| Schäfer, K | 4 |
| Ritis, K | 1 |
| Li, B | 1 |
| Fu, C | 1 |
| Ma, G | 1 |
| Fan, Q | 1 |
| Yao, Y | 1 |
| Degen, H | 1 |
| Borst, O | 4 |
| Ziegler, M | 1 |
| Mojica Munoz, AK | 1 |
| Jamasbi, J | 1 |
| Walker, B | 3 |
| Göbel, S | 1 |
| Fassbender, J | 1 |
| Adler, K | 1 |
| Brandl, R | 1 |
| Münch, G | 1 |
| Lorenz, R | 1 |
| Siess, W | 1 |
| Gawaz, M | 4 |
| Ungerer, M | 1 |
| Lu, DH | 1 |
| Huang, SW | 1 |
| Tu, HJ | 1 |
| Liou, HC | 1 |
| Liao, HM | 1 |
| Chen, CH | 1 |
| Fu, WM | 1 |
| Gau, SS | 1 |
| Hu, M | 2 |
| Luo, D | 3 |
| Yue, M | 2 |
| Wang, S | 2 |
| Chen, X | 1 |
| Zhou, Y | 3 |
| Cai, Y | 1 |
| Hu, X | 1 |
| Ke, Y | 1 |
| Yang, Z | 1 |
| Hu, H | 3 |
| Novotny, J | 1 |
| Chandraratne, S | 1 |
| Weinberger, T | 1 |
| Philippi, V | 1 |
| Stark, K | 1 |
| Ehrlich, A | 1 |
| Pircher, J | 2 |
| Konrad, I | 1 |
| Oberdieck, P | 1 |
| Titova, A | 1 |
| Hoti, Q | 1 |
| Schubert, I | 1 |
| Legate, KR | 1 |
| Urtz, N | 1 |
| Lorenz, M | 1 |
| Pelisek, J | 1 |
| Massberg, S | 1 |
| von Brühl, ML | 1 |
| Schulz, C | 1 |
| Misra, A | 1 |
| Prakash, P | 2 |
| Aggarwal, H | 1 |
| Dhankani, P | 1 |
| Kumar, S | 1 |
| Pandey, CP | 1 |
| Pugh, N | 1 |
| Bihan, D | 1 |
| Barthwal, MK | 1 |
| Farndale, RW | 1 |
| Dikshit, DK | 1 |
| Dikshit, M | 1 |
| Sheffield, WP | 3 |
| Eltringham-Smith, LJ | 3 |
| Bhakta, V | 3 |
| Assumpção, TC | 3 |
| Mizurini, DM | 3 |
| Monteiro, RQ | 3 |
| Ahlstedt, S | 1 |
| Reyes, M | 1 |
| Kotsyfakis, M | 3 |
| Mather, TN | 1 |
| Andersen, JF | 1 |
| Lukszo, J | 1 |
| Ribeiro, JMC | 1 |
| Francischetti, IMB | 1 |
| Zhou, J | 3 |
| Song, Z | 1 |
| Han, M | 1 |
| Yu, B | 1 |
| Lv, G | 1 |
| Han, N | 1 |
| Liu, Z | 1 |
| Yin, J | 1 |
| Kastetter, B | 1 |
| Matrai, AB | 1 |
| Cooley, BC | 5 |
| Liang, W | 1 |
| Fan, Y | 1 |
| Lu, H | 1 |
| Chang, Z | 1 |
| Hu, W | 1 |
| Sun, J | 1 |
| Wang, H | 1 |
| Zhu, T | 1 |
| Wang, J | 1 |
| Adili, R | 1 |
| Garcia-Barrio, MT | 1 |
| Holinstat, M | 1 |
| Eitzman, D | 1 |
| Zhang, J | 2 |
| Chen, YE | 1 |
| Moreno, A | 1 |
| Pitoc, GA | 1 |
| Ganson, NJ | 1 |
| Layzer, JM | 1 |
| Hershfield, MS | 1 |
| Tarantal, AF | 1 |
| Sullenger, BA | 1 |
| Spasov, AA | 1 |
| Kucheryavenko, AF | 1 |
| Sirotenko, VS | 1 |
| Anisimova, VA | 1 |
| Divaeva, LN | 1 |
| Kuz'menko, TA | 1 |
| Morkovnik, AS | 1 |
| Guenther, F | 1 |
| Herr, N | 1 |
| Mauler, M | 1 |
| Witsch, T | 1 |
| Roming, F | 1 |
| Hein, L | 1 |
| Boeynaems, JM | 1 |
| Robaye, B | 1 |
| Idzko, M | 1 |
| Bode, C | 2 |
| Von Zur Muhlen, C | 2 |
| Duerschmied, D | 1 |
| Li, Y | 3 |
| Qi, Y | 1 |
| Ribeiro, JM | 2 |
| Francischetti, IM | 2 |
| Lei, X | 1 |
| Reheman, A | 1 |
| Hou, Y | 1 |
| Zhou, H | 1 |
| Marshall, AH | 1 |
| Liang, C | 1 |
| Dai, X | 1 |
| Li, BX | 1 |
| Vanhoorelbeke, K | 2 |
| Ni, H | 1 |
| Gupta, N | 3 |
| Li, W | 5 |
| Willard, B | 1 |
| Silverstein, RL | 5 |
| McIntyre, TM | 5 |
| Münzer, P | 3 |
| Schmid, E | 1 |
| Feijge, MA | 1 |
| Cosemans, JM | 3 |
| Chatterjee, M | 4 |
| Schmidt, EM | 2 |
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| Towhid, ST | 1 |
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| Ivanov, IS | 1 |
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| Williams, CM | 2 |
| Mattheij, NJ | 1 |
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| Alzoubi, K | 1 |
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| Zhou, Q | 1 |
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| Zhu, W | 1 |
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| Wang, Z | 2 |
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| Fu, X | 1 |
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| Qin, YR | 1 |
| You, SJ | 1 |
| Li, Q | 1 |
| Wang, XH | 1 |
| Hu, LF | 1 |
| Liu, CF | 1 |
| Cui, H | 1 |
| Tan, YX | 1 |
| Österholm, C | 1 |
| Hedin, U | 1 |
| Vlodavsky, I | 1 |
| Li, JP | 1 |
| Covarrubias, R | 1 |
| Chepurko, E | 1 |
| Reynolds, A | 1 |
| Huttinger, ZM | 1 |
| Huttinger, R | 1 |
| Stanfill, K | 1 |
| Wheeler, DG | 1 |
| Novitskaya, T | 1 |
| Robson, SC | 1 |
| Dwyer, KM | 1 |
| Cowan, PJ | 1 |
| Gumina, RJ | 1 |
| Dhanesha, N | 1 |
| Doddapattar, P | 1 |
| Khanna, I | 1 |
| Pollpeter, MJ | 1 |
| Nayak, MK | 1 |
| Staber, JM | 1 |
| Chauhan, AK | 4 |
| Zhao, Z | 1 |
| Wang, R | 1 |
| Huo, Z | 1 |
| Li, C | 1 |
| Tien, AJ | 1 |
| Chueh, TH | 1 |
| Hsia, CP | 1 |
| Chien, CT | 1 |
| Xin, G | 1 |
| Wei, Z | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| TOLERANCE STUDY OF N-ACETYLCYSTEINE FOR THROMBOLYSIS IN THE ACUTE PHASE OF ISCHEMIC STROKE / ETUDE DE TOLERANCE DE LA N-ACETYLCYSTEINE POUR LA THROMBOLYSE A LA PHASE AIGUË DE L'INFARCTUS CEREBRAL[NCT04920448] | Phase 2 | 19 participants (Anticipated) | Interventional | 2021-06-07 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for chlorine and Blood Clot
| Article | Year |
|---|---|
Involvement of neutrophils in thrombus formation in living mice.
Topics: Animals; Arteries; Blood Proteins; Chlorides; Computer Systems; Cytoplasmic Granules; Disease Models | 2014 |
Pathogenesis of thrombosis.
Topics: Animals; Blood Coagulation Factors; Cell-Derived Microparticles; Chlorides; Collagen; Disease Models | 2009 |
Tissue factor and thrombosis models.
Topics: Animals; Blood Coagulation; Blood Vessels; Chlorides; Disease Models, Animal; Evidence-Based Medicin | 2010 |
Murine models of vascular thrombosis (Eitzman series).
Topics: Animals; Atherosclerosis; Blood Coagulation; Blood Vessels; Chlorides; Collagen; Disease Models, Ani | 2007 |
The relationship between surface charge (potential characteristics) of the vascular interface and thrombosis.
Topics: Animals; Blood Cells; Blood Sedimentation; Blood Vessel Prosthesis; Blood Vessels; Capillary Permeab | 1983 |
The rôle of surface phenomena in intravascular thrombosis.
Topics: Biological Transport; Biological Transport, Active; Blood Vessel Prosthesis; Blood Vessels; Calcium; | 1973 |
202 other studies available for chlorine and Blood Clot
| Article | Year |
|---|---|
Repeated Social Defeat Exaggerates Fibrin-Rich Clot Formation by Enhancing Neutrophil Extracellular Trap Formation via Platelet-Neutrophil Interactions.
Topics: Animals; Antibodies; Blood Coagulation; Blood Platelets; CD11b Antigen; Cell Communication; Chloride | 2021 |
Evaluation of Sida cordifolia L. for its potential against thrombosis in experimental models.
Topics: Animals; Anticoagulants; Carrageenan; Chlorides; Collagen; Epinephrine; Female; Ferric Compounds; Lu | 2022 |
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Topics: Allosteric Regulation; Animals; Anticoagulants; Blood Coagulation; Chlorides; Disease Models, Animal | 2019 |
Antithrombotic Effect of Artemisia princeps Pampanini Extracts in Vitro and in FeCl
Topics: Adult; Animals; Artemisia; Cell Adhesion; Cell Adhesion Molecules; Chlorides; Female; Ferric Compoun | 2019 |
Cyclic RGD functionalized liposomes targeted to activated platelets for thrombosis dual-mode magnetic resonance imaging.
Topics: Animals; Blood Platelets; Chlorides; Ferric Compounds; Gadolinium DTPA; Liposomes; Magnetic Resonanc | 2020 |
Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs.
Topics: Animals; Anticoagulants; Blood Coagulation; Chlorides; Cloning, Molecular; Disease Models, Animal; D | 2020 |
Aqueous extract of Whitmania pigra Whitman ameliorates ferric chloride-induced venous thrombosis in rats via antioxidation.
Topics: Animals; Antioxidants; Chlorides; Ferric Compounds; Leeches; NF-E2-Related Factor 2; Oxidative Stres | 2021 |
Thrombospondin-1 promotes hemostasis through modulation of cAMP signaling in blood platelets.
Topics: Animals; Bleeding Time; Blood Platelets; CD36 Antigens; Cells, Cultured; Chlorides; Cyclic AMP; Cycl | 2021 |
Adenosine Receptor Agonist HE-NECA Enhances Antithrombotic Activities of Cangrelor and Prasugrel in vivo by Decreasing of Fibrinogen Density in Thrombus.
Topics: Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Adult; Animals; Antithrombins; Blood Pre | 2021 |
Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.
Topics: Animals; Blood Platelets; Carrier Proteins; Cells, Cultured; Chlorides; Disease Models, Animal; Enzy | 2017 |
Fibrin-Targeted and H
Topics: Animals; Boronic Acids; Carotid Artery Thrombosis; CD40 Ligand; Cell Survival; Chlorides; Drug Carri | 2017 |
Potent Thrombolytic Effect of
Topics: Acetylcysteine; Animals; Blood Platelets; Chlorides; Disease Models, Animal; Ferric Compounds; Fibri | 2017 |
Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis.
Topics: Animals; Chlorides; Endothelial Cells; Ferric Compounds; Hemostasis; Immunohistochemistry; Lipoprote | 2017 |
Trowaglerix Venom Polypeptides As a Novel Antithrombotic Agent by Targeting Immunoglobulin-Like Domains of Glycoprotein VI in Platelet.
Topics: Animals; Binding Sites; Blood Platelets; Carotid Artery Injuries; Chlorides; Computer-Aided Design; | 2017 |
Platelets Express Activated P2Y
Topics: Adenosine Monophosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Cell Line; Chlorides; Cy | 2017 |
Interferon lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-driven thromboinflammation.
Topics: Animals; Autophagy; Blood Coagulation; Blood Platelets; Case-Control Studies; Chlorides; Disease Mod | 2017 |
Photoacoustic Imaging: A Novel Tool for Detecting Carotid Artery Thrombosis in Mice.
Topics: Animals; Biopsy; Carotid Artery Diseases; Carotid Artery, Common; Chlorides; Disease Models, Animal; | 2017 |
ADPase CD39 Fused to Glycoprotein VI-Fc Boosts Local Antithrombotic Effects at Vascular Lesions.
Topics: Animals; Antigens, CD; Apyrase; Carotid Artery Diseases; Carotid Artery Injuries; Chlorides; Disease | 2017 |
ARHGEF10 knockout inhibits platelet aggregation and protects mice from thrombus formation.
Topics: Animals; Arterial Occlusive Diseases; Blood Platelets; Carotid Artery Diseases; Cell Shape; Chloride | 2017 |
Class III PI3K Positively Regulates Platelet Activation and Thrombosis via PI(3)P-Directed Function of NADPH Oxidase.
Topics: Adult; Animals; Autophagy; Blood Coagulation; Blood Platelets; Chlorides; Class III Phosphatidylinos | 2017 |
Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.
Topics: Aged; Animals; Chlorides; Coronary Vessels; Disease Models, Animal; Female; Ferric Compounds; Humans | 2018 |
Anti-thrombotic efficacy of S007-867: Pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro.
Topics: Animals; Aspirin; Blood Coagulation; Chlorides; Clopidogrel; Dose-Response Relationship, Drug; Ferri | 2018 |
Fusion to Human Serum Albumin Extends the Circulatory Half-Life and Duration of Antithrombotic Action of the Kunitz Protease Inhibitor Domain of Protease Nexin 2.
Topics: Amyloid beta-Protein Precursor; Animals; Area Under Curve; Blood Coagulation Factors; Chlorides; Chr | 2018 |
Ixonnexin from Tick Saliva Promotes Fibrinolysis by Interacting with Plasminogen and Tissue-Type Plasminogen Activator, and Prevents Arterial Thrombosis.
Topics: Animals; Arterial Occlusive Diseases; Chlorides; Ferric Compounds; Fibrinolysis; Mice; Noxae; Plasmi | 2018 |
Evaluation of the antithrombotic activity of Zhi-Xiong Capsules, a Traditional Chinese Medicinal formula, via the pathway of anti-coagulation, anti-platelet activation and anti-fibrinolysis.
Topics: Acute Disease; Animals; Anticoagulants; Antithrombins; Aspirin; Blood Coagulation; Capsules; Carotid | 2018 |
Optimizing outcome measurement with murine ferric chloride-induced thrombosis.
Topics: Animals; Carotid Arteries; Chlorides; Factor IX; Ferric Compounds; Hemophilia B; Mice; Mice, Knockou | 2018 |
KLF11 (Krüppel-Like Factor 11) Inhibits Arterial Thrombosis via Suppression of Tissue Factor in the Vascular Wall.
Topics: Animals; Antithrombin III; Apoptosis Regulatory Proteins; Bone Marrow Transplantation; Cells, Cultur | 2019 |
Anti-PEG Antibodies Inhibit the Anticoagulant Activity of PEGylated Aptamers.
Topics: Animals; Antibodies; Anticoagulants; Antigen-Antibody Reactions; Aptamers, Nucleotide; Chlorides; Di | 2019 |
Antithrombotic Activity of a Novel Diazepino[1,2-α] Benzimidazole Derivative on Arterial Thrombosis Model in Rats without Concomitant Pathology and in Rats with Experimental Myocardial Infarction.
Topics: Animals; Animals, Outbred Strains; Aspirin; Azepines; Benzimidazoles; Blood Coagulation Tests; Chlor | 2019 |
Contrast ultrasound for the quantification of deep vein thrombosis in living mice: effects of enoxaparin and P2Y12 receptor inhibition.
Topics: Adenosine; Animals; Anticoagulants; Chlorides; Contrast Media; Enoxaparin; Ferric Compounds; Male; M | 2013 |
Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo.
Topics: Animals; Anticoagulants; Bradykinin; Chiroptera; Chlorides; Disease Models, Animal; Factor Xa; Facto | 2013 |
Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis.
Topics: Animals; Binding Sites; Blood Platelets; Chlorides; Crotalid Venoms; Disease Models, Animal; Female; | 2014 |
Proteasome proteolysis supports stimulated platelet function and thrombosis.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell-Derived Microparticles; Chlorides; Cytoskeleta | 2014 |
Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation.
Topics: Adenosine Triphosphate; Animals; Blood Platelets; Calcium; Cell Degranulation; Cell Membrane; Cerami | 2014 |
Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice.
Topics: Animals; Blood Platelets; Carotid Arteries; Cells, Cultured; Chlorides; Disintegrins; Dose-Response | 2013 |
Cyclophilin A is an important mediator of platelet function by regulating integrin αIIbβ3 bidirectional signalling.
Topics: Animals; Blood Platelets; Cell Adhesion; Cells, Cultured; Chlorides; Cyclophilin A; Cytoskeleton; Fe | 2014 |
The flavonols quercetin and 3',4'-dihydroxyflavonol reduce platelet function and delay thrombus formation in a model of type 1 diabetes.
Topics: Animals; Antioxidants; Blood Platelets; Carotid Arteries; Carotid Artery Injuries; Chlorides; Diabet | 2014 |
Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation.
Topics: Amino Acid Substitution; Animals; Chlorides; Collagen; Disease Models, Animal; Ferric Compounds; HEK | 2014 |
RUC-4: a novel αIIbβ3 antagonist for prehospital therapy of myocardial infarction.
Topics: Animals; Binding Sites; Blood Platelets; Carotid Stenosis; Chlorides; Disease Models, Animal; Emerge | 2014 |
Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro-atherothombotic cellular functions.
Topics: Animals; Blood Platelets; Carotid Artery Diseases; CD36 Antigens; Cell-Derived Microparticles; Chlor | 2014 |
Thymidine phosphorylase participates in platelet signaling and promotes thrombosis.
Topics: Amino Acid Sequence; Animals; Blood Platelets; Bone Marrow Transplantation; Chlorides; Enzyme Inhibi | 2014 |
Murine models in the evaluation of heparan sulfate-based anticoagulants.
Topics: Animals; Anticoagulants; Chlorides; Disease Models, Animal; Ferric Compounds; Hemorrhage; Heparitin | 2015 |
The β isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in αII b β3 integrin signaling.
Topics: Animals; Blood Platelets; Calcineurin; Carotid Arteries; Catalytic Domain; Cell Adhesion; Chlorides; | 2014 |
Aspirin enhances protective effect of fish oil against thrombosis and injury-induced vascular remodelling.
Topics: Animals; Aspirin; Chlorides; Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; | 2015 |
Fasxiator, a novel factor XIa inhibitor from snake venom, and its site-specific mutagenesis to improve potency and selectivity.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Blood Coagulation; Bungarotoxins; Bungarus; Caro | 2015 |
Defective thrombus formation in mice lacking endogenous factor VII activating protease (FSAP).
Topics: Animals; Blood Coagulation Tests; Carotid Arteries; Carotid Artery Diseases; Chlorides; Collagen; Di | 2015 |
A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models.
Topics: Animals; Chlorides; Disease Models, Animal; Ferric Compounds; Hirudins; Humans; Mice; Rabbits; Recom | 2015 |
Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo.
Topics: Animals; Basigin; Blood Platelets; Carotid Artery Injuries; Cell Degranulation; Chlorides; Cyclophil | 2015 |
Kaempferol suppresses collagen-induced platelet activation by inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation.
Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Chlorides; Collagen; Ferric Compounds; Humans; Intrace | 2015 |
Arterial thrombosis is accelerated in mice deficient in histidine-rich glycoprotein.
Topics: Animals; Blood Coagulation; Chlorides; Factor XII; Female; Ferric Compounds; Gene Deletion; Gene Kno | 2015 |
Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability.
Topics: Animals; Cell Line; Chlorides; Disease Models, Animal; Factor IX; Ferric Compounds; Gene Expression | 2015 |
Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach.
Topics: Aspirin; Biomechanical Phenomena; Blood Platelets; Cell Aggregation; Chlorides; Erythrocytes; Ferric | 2015 |
Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Chlorides; Disease Models, | 2015 |
Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel.
Topics: Animals; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Ferric Compounds; Male; Mesen | 2015 |
Factor XII full and partial null in rat confers robust antithrombotic efficacy with no bleeding.
Topics: Animals; Arteriovenous Shunt, Surgical; Chlorides; Disease Models, Animal; Dose-Response Relationshi | 2015 |
Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets.
Topics: Acetazolamide; Actomyosin; Amides; Animals; Anoctamins; Blood Coagulation Disorders; Blood Platelets | 2015 |
Leukemia-associated Rho guanine-nucleotide exchange factor is not critical for RhoA regulation, yet is important for platelet activation and thrombosis in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; | 2015 |
Small molecule PZL318: forming fluorescent nanoparticles capable of tracing their interactions with cancer cells and activated platelets, slowing tumor growth and inhibiting thrombosis.
Topics: Animals; Blood Platelets; Carbolines; Cell Line, Tumor; Cell Proliferation; Chlorides; Circular Dich | 2015 |
CD44 sensitivity of platelet activation, membrane scrambling and adhesion under high arterial shear rates.
Topics: Animals; Apoptosis; Blood Coagulation; Blood Platelets; Calcium Channels; Calcium Signaling; Caspase | 2016 |
Deubiquitinases Modulate Platelet Proteome Ubiquitination, Aggregation, and Thrombosis.
Topics: Aminopyridines; Animals; Benzoates; Blood Platelets; Chlorides; Disease Models, Animal; Enzyme Inhib | 2015 |
Prevention of occlusive arterial thrombus formation by a single loading dose of prasugrel suppresses neointimal hyperplasia in mice.
Topics: Adenosine Diphosphate; Animals; Aorta; Arterial Occlusive Diseases; Arteries; Carotid Arteries; Chem | 2015 |
Ferric chloride thrombosis model: unraveling the vascular effects of a highly corrosive oxidant.
Topics: Animals; Caustics; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, | 2015 |
The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis.
Topics: Amino Acid Motifs; Animals; Blood Coagulation; Blood Platelets; Chlorides; Fibrin; Humans; Iron Comp | 2015 |
Misshapen/NIK-related kinase (MINK1) is involved in platelet function, hemostasis, and thrombus formation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chlorides; Ferric Compounds; MAP Kinase Signaling S | 2016 |
Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.
Topics: Animals; Blood Platelets; Calcium; Carotid Artery Injuries; Cecum; Chlorides; Choline; Diet; Female; | 2016 |
Hydrogen sulfide attenuates ferric chloride-induced arterial thrombosis in rats.
Topics: Animals; Chlorides; Ferric Compounds; Hydrogen Sulfide; Male; Mice; Mice, Inbred C57BL; Rats; Signal | 2016 |
Heparanase expression upregulates platelet adhesion activity and thrombogenicity.
Topics: Animals; Blood Platelets; Carotid Arteries; Cell Separation; Chlorides; Crosses, Genetic; Erythrocyt | 2016 |
Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; | 2016 |
Endothelial Cell-Derived von Willebrand Factor Is the Major Determinant That Mediates von Willebrand Factor-Dependent Acute Ischemic Stroke by Promoting Postischemic Thrombo-Inflammation.
Topics: ADAMTS13 Protein; Animals; Blood Platelets; Bone Marrow Transplantation; Carotid Artery Diseases; Ch | 2016 |
Characterization of the Anticoagulant and Antithrombotic Properties of the Sphingosine 1-Phosphate Mimetic FTY720.
Topics: Adenosine Diphosphate; Animals; Anticoagulants; Arteriovenous Shunt, Surgical; Biomimetic Materials; | 2017 |
Monascus Adlay and Monacolin K Attenuates Arterial Thrombosis in Rats through the Inhibition of ICAM-1 and Oxidative Stress.
Topics: Animals; Carotid Arteries; Chlorides; Ferric Compounds; Intercellular Adhesion Molecule-1; Lovastati | 2016 |
Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release.
Topics: Animals; Antioxidants; Beer; Carotid Arteries; Cell Adhesion Molecules; Chlorides; Dendritic Cells; | 2017 |
Store-operated Ca(2+) entry in platelets occurs independently of transient receptor potential (TRP) C1.
Topics: Animals; Blood Coagulation; Blood Platelets; Calcium; Calcium Signaling; Chlorides; Disease Models, | 2008 |
Restoration of plasma von Willebrand factor deficiency is sufficient to correct thrombus formation after gene therapy for severe von Willebrand disease.
Topics: alpha 1-Antitrypsin; Animals; Bleeding Time; Chlorides; Cytomegalovirus; Disease Models, Animal; Fac | 2008 |
Salsolinol, an endogenous neurotoxin, enhances platelet aggregation and thrombus formation.
Topics: Adrenergic Antagonists; Animals; Blood Platelets; Cell Survival; Chlorides; Cyclic AMP; Disease Mode | 2008 |
Deficiency of LRP8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis.
Topics: Animals; Apolipoprotein E3; Blood Platelets; Chlorides; Ferric Compounds; Humans; LDL-Receptor Relat | 2009 |
Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury.
Topics: Animals; Aorta; Carotid Artery Thrombosis; Chlorides; Enzyme-Linked Immunosorbent Assay; Female; Fer | 2009 |
Antithrombotic effects due to pharmacological modulation of thrombin-activatable fibrinolysis inhibitor in rats.
Topics: Animals; Bleeding Time; Blood Coagulation Tests; Carboxypeptidase B2; Chlorides; Disease Models, Ani | 2008 |
Characterization of calcium- and integrin-binding protein 1 (CIB1) knockout platelets: potential compensation by CIB family members.
Topics: Animals; Binding Sites; Blood Platelets; Calcium-Binding Proteins; Cells, Cultured; Chlorides; Disea | 2008 |
Outcomes of kidney transplantation in children with nephronophthisis: an analysis of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) Registry.
Topics: Adolescent; Child; Child, Preschool; Chlorides; Chromium Compounds; Female; Genes, Recessive; Graft | 2008 |
Platelet P2Y(12) receptor influences the vessel wall response to arterial injury and thrombosis.
Topics: Animals; Atherosclerosis; Blood Platelets; Bone Marrow Transplantation; Chlorides; Disease Models, A | 2009 |
The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation.
Topics: ADAMTS13 Protein; Animals; Arterioles; Chlorides; Ferric Compounds; Metalloendopeptidases; Mice; Mic | 2009 |
Nicorandil attenuates FeCl(3)-induced thrombus formation through the inhibition of reactive oxygen species production.
Topics: Animals; Anti-Arrhythmia Agents; Arteries; Cells, Cultured; Chlorides; Collagen; Decanoic Acids; End | 2009 |
Autoantibodies to heat shock protein 60 promote thrombus formation in a murine model of arterial thrombosis.
Topics: Animals; Arterial Occlusive Diseases; Autoantibodies; Carotid Artery Diseases; Chaperonin 60; Chlori | 2009 |
Erythrocyte hemolysis and hemoglobin oxidation promote ferric chloride-induced vascular injury.
Topics: Animals; Aorta; Chlorides; Endothelium, Vascular; Erythrocytes; Female; Ferric Compounds; Fibrinolyt | 2009 |
Renal and cardiovascular characterization of COX-2 knockdown mice.
Topics: Animals; Blood Pressure; Blood Urea Nitrogen; Cardiovascular System; Cells, Cultured; Chlorides; Cyc | 2009 |
Enhanced atherothrombotic formation after oxidative injury by FeCl3 to the common carotid artery in severe combined hyperlipidemic mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Carotid Artery, Common; Chlorides; Disease Models, Anim | 2009 |
Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Cells, C | 2009 |
A platelet tetraspanin superfamily member, CD151, is required for regulation of thrombus growth and stability in vivo.
Topics: Animals; Antigens, CD; Arterioles; Blood Platelets; Chlorides; Endothelium; Ferric Compounds; Mice; | 2009 |
A ferric chloride induced arterial injury model used as haemostatic effect model.
Topics: Animals; Carotid Artery Diseases; Chlorides; Disease Models, Animal; Dose-Response Relationship, Dru | 2010 |
Imaging of structural changes in endothelial cells and thrombus formation at the site of FeCl(3)-induced injuries in mice cremasteric arteries.
Topics: Animals; Arteries; Aspirin; Blood Platelets; Chlorides; Clopidogrel; Dose-Response Relationship, Dru | 2009 |
Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo.
Topics: Animals; Bleeding Time; Blood Platelets; Cell Lineage; Cells, Cultured; Chlorides; Class I Phosphati | 2010 |
Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions.
Topics: Amino Acid Substitution; Animals; Blood Platelets; Chlorides; Disease Models, Animal; Ferric Compoun | 2010 |
Enhanced platelet reactivity and thrombosis in Apoe-/- mice exposed to cigarette smoke is attenuated by P2Y12 antagonism.
Topics: Adenosine Monophosphate; Animals; Apolipoproteins E; Blood Platelets; Chlorides; Female; Ferric Comp | 2010 |
AMPK α2 subunit is involved in platelet signaling, clot retraction, and thrombus stability.
Topics: AMP-Activated Protein Kinases; Animals; Blood Platelets; Chlorides; Clot Retraction; Ferric Compound | 2010 |
In vivo models for the evaluation of antithrombotics and thrombolytics.
Topics: Animals; Cardiopulmonary Bypass; Chlorides; Constriction, Pathologic; Disease Models, Animal; Dogs; | 2010 |
Evaluation of AR-H067637, the active metabolite of the new direct thrombin inhibitor AZD0837, in models of venous and arterial thrombosis and bleeding in anaesthetised rats.
Topics: Amidines; Animals; Antithrombin III; Antithrombins; Azetidines; Blood Coagulation; Chlorides; Daltep | 2010 |
Platelets enhance lymphocyte adhesion and infiltration into arterial thrombus.
Topics: Adult; Animals; Antibodies, Monoclonal; Arterioles; B-Lymphocytes; Blood Platelets; CD40 Ligand; Chl | 2010 |
Deletion of the high-density lipoprotein receptor scavenger receptor BI in mice modulates thrombosis susceptibility and indirectly affects platelet function by elevation of plasma free cholesterol.
Topics: Animals; Arterial Occlusive Diseases; Blood Platelets; Bone Marrow Transplantation; Chlorides; Chole | 2011 |
Mechanisms underlying FeCl3-induced arterial thrombosis.
Topics: Animals; Anticoagulants; Carotid Arteries; Chlorides; Disease Models, Animal; Ferric Compounds; Mice | 2011 |
Possible mechanism of preventive effects of coffee intake on the formation of arterial occlusive thrombosis.
Topics: Animals; Arteries; Caffeine; Chlorides; Coffee; Endothelium, Vascular; Humans; Imaging, Three-Dimens | 2010 |
Thrombotic distal middle cerebral artery occlusion produced by topical FeCl(3) application: a novel model suitable for intravital microscopy and thrombolysis studies.
Topics: Administration, Topical; Animals; Chlorides; Ferric Compounds; Infarction, Middle Cerebral Artery; M | 2011 |
Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice.
Topics: Animals; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Drug Resistance; Ferric Compo | 2011 |
A ride with ferric chloride.
Topics: Animals; Chlorides; Ferric Compounds; Humans; Mice; Thrombosis | 2011 |
In vivo fluorescence imaging of large-vessel thrombosis in mice.
Topics: Animals; Blood Coagulation Factors; Blood Platelets; Chlorides; Ferric Compounds; Mice; Mice, Inbred | 2011 |
Evaluation of anti-platelet and anti-thrombotic effects of cilostazol with PFA-100® and Multiplate® whole blood aggregometer in vitro, ex vivo and FeCl3-induced thrombosis models in vivo.
Topics: Animals; Blood Platelets; Chlorides; Cilostazol; Ferric Compounds; Fibrinolytic Agents; Male; Mice; | 2011 |
Genetic and antibody-induced glycoprotein VI deficiency equally protects mice from mechanically and FeCl(3) -induced thrombosis.
Topics: Animals; Antibodies; Chlorides; Ferric Compounds; Mechanical Phenomena; Mice; Platelet Membrane Glyc | 2011 |
Inducible nitric oxide synthase provides protection against injury-induced thrombosis in female mice.
Topics: Analysis of Variance; Animals; Aorta; Blood Coagulation; Cardiomegaly; Carotid Arteries; Carotid Art | 2011 |
Enzymatic single-chain antibody tagging: a universal approach to targeted molecular imaging and cell homing in cardiovascular disease.
Topics: Aminoacyltransferases; Animals; Bacterial Proteins; Blood Platelets; Cell Movement; Cell Tracking; C | 2011 |
Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.
Topics: ADAM Proteins; ADAMTS13 Protein; Animals; Antibodies, Monoclonal; Carotid Stenosis; Chlorides; Disea | 2011 |
Procoagulant activity induced by vascular injury determines contribution of elevated factor VIII to thrombosis and thrombus stability in mice.
Topics: Animals; Antithrombin III; Carotid Artery Injuries; Cells, Cultured; Chlorides; Factor VIII; Ferric | 2011 |
Diminished thrombogenic responses by deletion of the Podocalyxin Gene in mouse megakaryocytes.
Topics: Animals; Blood Coagulation; Blood Platelets; Carotid Arteries; Cell Count; Chlorides; Ferric Compoun | 2011 |
An antithrombotic fucoidan, unlike heparin, does not prolong bleeding time in a murine arterial thrombosis model: a comparative study of Undaria pinnatifida sporophylls and Fucus vesiculosus.
Topics: Animals; Anticoagulants; Bleeding Time; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrino | 2012 |
A NOD/SCID mouse model for the assessment of human platelet aggregation in vivo.
Topics: Animals; Blood Platelets; Cell Survival; Chlorides; Ferric Compounds; Humans; Platelet Aggregation I | 2012 |
Defective diacylglycerol-induced Ca2+ entry but normal agonist-induced activation responses in TRPC6-deficient mouse platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; C-Reactive Protein; Calcium Channels; Calcium Signa | 2012 |
Identification of galectin-1 and galectin-3 as novel partners for von Willebrand factor.
Topics: Animals; Cells, Cultured; Chlorides; Disease Models, Animal; Ferric Compounds; Galectin 1; Galectin | 2012 |
Reduction of thrombus size in murine models of thrombosis following administration of recombinant α1-proteinase inhibitor mutant proteins.
Topics: alpha 1-Antitrypsin; Animals; Antithrombins; Carotid Artery Injuries; Chlorides; Disease Models, Ani | 2012 |
Use of a mouse model to elucidate the phenotypic effects of the von Willebrand factor cleavage mutants, Y1605A/M1606A and R1597W.
Topics: ADAMTS13 Protein; Animals; Blood Coagulation; Blotting, Western; Chlorides; Disease Models, Animal; | 2012 |
Effects of plasma kallikrein deficiency on haemostasis and thrombosis in mice: murine ortholog of the Fletcher trait.
Topics: Animals; Bleeding Time; Chlorides; Disease Models, Animal; Ferric Compounds; Hemorrhage; Hemostasis; | 2012 |
The mouse dorsal skinfold chamber as a model for the study of thrombolysis by intravital microscopy.
Topics: Animals; Chlorides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ferric Compoun | 2012 |
Cationic derivative of dextran reverses anticoagulant activity of unfractionated heparin in animal models of arterial and venous thrombosis.
Topics: Animals; Anticoagulants; Bleeding Time; Blood Coagulation; Chlorides; Dextrans; Disease Models, Anim | 2012 |
Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo.
Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents; Blood Coagulation; Calorimetry; Cell Line, T | 2012 |
BF066, a novel dual target antiplatelet agent without significant bleeding.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenine; Adenosine; Adenosine Di | 2012 |
Increased platelet activation and thrombosis in transgenic mice expressing constitutively active P2Y12.
Topics: Adenosine Monophosphate; Animals; Bleeding Time; Blood Platelets; Chlorides; Cyclic AMP; Disease Mod | 2012 |
A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor.
Topics: ADAMTS13 Protein; Animals; Antibodies, Monoclonal; Chlorides; Collagen; Disease Models, Animal; Enzy | 2012 |
Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10.
Topics: Animals; Arteries; Blood Platelets; Chlorides; Collagen; Cytoplasmic Granules; Ferric Compounds; Gen | 2012 |
Oxidation inhibits iron-induced blood coagulation.
Topics: Adult; Blood Coagulation; Chlorides; Female; Ferric Compounds; Fibrin; Fibrinogen; Humans; Hydrogen | 2013 |
In vitro and in vivo evaluation of the effect of elevated factor VIII on the thrombogenic process.
Topics: Animals; Antithrombin III; Blood Coagulation; Chlorides; Disease Models, Animal; Factor VIII; Ferric | 2013 |
GDF-15 prevents platelet integrin activation and thrombus formation.
Topics: Animals; Bleeding Time; Blood Platelets; Chlorides; Collagen; Cyclic AMP-Dependent Protein Kinases; | 2013 |
Red blood cells mediate the onset of thrombosis in the ferric chloride murine model.
Topics: Animals; Cells, Cultured; Chlorides; Disease Models, Animal; Erythrocyte Aggregation; Erythrocytes; | 2013 |
Mice with a severe deficiency of the endothelial protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge.
Topics: Animals; Arteries; Blood Coagulation Factors; Chlorides; Embryonic and Fetal Development; Ferric Com | 2002 |
Protection against thrombosis in mice lacking PAR3.
Topics: Animals; Arterioles; Bleeding Time; Chlorides; Enzyme Activation; Female; Ferric Compounds; Genotype | 2002 |
Anti-thrombotic activity of PDR, a newly synthesized L-Arg derivative, on three thrombosis models in rats.
Topics: Adenosine Diphosphate; Animals; Arginine; Arteriovenous Shunt, Surgical; Autacoids; Chlorides; Colla | 2003 |
Unusual psychiatric manifestations of neurological disease.
Topics: Chlorides; Humans; Hyponatremia; Intracranial Embolism; Intracranial Embolism and Thrombosis; Mening | 1959 |
[DETERMINATION OF THE POSSIBILITY OF DICOUMARIN PREVENTION OF THROMBUS FORMATION CAUSED BY INTRAVENOUS ADMINISTRATION OF MASSIVE DOSES OF THROMBOPLASTIN].
Topics: Administration, Intravenous; Atherosclerosis; Chlorides; Chlorpromazine; Dicumarol; Diet; Diet, Athe | 1964 |
POSSIBLE RELATIONSHIP OF IONIC STRUCTURE OF THE BLOOD-INTIMAL INTERFACE TO INTRAVASCULAR THROMBOSIS.
Topics: Animals; Biological Transport; Blood Cells; Blood Coagulation; Blood Proteins; Blood Vessels; Calciu | 1964 |
[DETERMINATION OF ENDOTHELIUM-DAMAGING EFFECTS OF INJECTABLE SOLUTIONS. EFFECT OF THE OSMOTIC PRESSURE ON THE PH].
Topics: Acid-Base Equilibrium; Blood Viscosity; Chlorides; Endothelium; Glucose; Isotonic Solutions; Osmosis | 1965 |
Cause-effect relation between hyperfibrinogenemia and vascular disease.
Topics: Animals; Carotid Arteries; Chlorides; Cross-Linking Reagents; Dimerization; Disease Models, Animal; | 2004 |
Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivo.
Topics: Animals; Antioxidants; Bilirubin; Chlorides; Chromans; Enzyme Induction; Enzyme Inhibitors; Ferric C | 2004 |
Molecular imaging of factor XIIIa activity in thrombosis using a novel, near-infrared fluorescent contrast agent that covalently links to thrombi.
Topics: alpha-2-Antiplasmin; Animals; Chlorides; Contrast Media; Cross-Linking Reagents; Factor XIIIa; Feasi | 2004 |
In vitro and in vivo antithrombotic activity of PD-198961, a novel synthetic factor Xa inhibitor.
Topics: Animals; Bleeding Time; Chlorides; Dogs; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Fer | 2004 |
The combination of modified antioxidant enzymes for anti-thrombotic protection of the vascular wall: the significance of covalent connection of superoxide dismutase and catalase activities.
Topics: Animals; Antioxidants; Catalase; Chlorides; Chondroitin Sulfates; Disease Models, Animal; Ferric Com | 2004 |
An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research.
Topics: Animals; Arterial Occlusive Diseases; Carotid Artery Diseases; Chlorides; Clopidogrel; Disease Model | 2005 |
Combined effects of a factor Xa inhibitor YM466 and a GPIIb/IIIa antagonist YM128 on thrombosis and neointima formation in mice.
Topics: Angioplasty; Animals; Bleeding Time; Blood Coagulation; Blood Platelets; Carotid Arteries; Carotid A | 2004 |
Role of p38 mitogen-activated protein kinase in thrombus formation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alleles; Animals; Blood Coagulat | 2004 |
Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice.
Topics: Animals; Arteries; Aspirin; Bleeding Time; Blood Flow Velocity; Carotid Arteries; Carotid Artery Dis | 2005 |
Evaluation of two experimental venous thrombosis models in the rat.
Topics: Animals; Blood Coagulation Tests; Chlorides; Disease Models, Animal; Female; Ferric Compounds; Hemos | 2005 |
Pharmacological properties of YM-254890, a specific G(alpha)q/11 inhibitor, on thrombosis and neointima formation in mice.
Topics: Administration, Oral; Animals; Blood Pressure; Carotid Arteries; Cell Proliferation; Chlorides; Chro | 2005 |
Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activation.
Topics: Animals; Blood Platelets; Cells, Cultured; Chlorides; Ferric Compounds; Gene Expression Regulation, | 2005 |
Platelet PECAM-1 inhibits thrombus formation in vivo.
Topics: Animals; Blood Coagulation; Blood Platelets; Bone Marrow; Carotid Arteries; Chlorides; Female; Ferri | 2006 |
Thrombotic phenotype of mice with a combined deficiency in plasminogen activator inhibitor 1 and vitronectin.
Topics: Animals; Chlorides; Ferric Compounds; Mice; Mice, Knockout; Phenotype; Plasminogen Activator Inhibit | 2005 |
Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo.
Topics: Animals; Chlorides; Ferric Compounds; Hirudins; Lasers; Mice; Mice, Knockout; Platelet Membrane Glyc | 2006 |
Plasminogen activator inhibitor-1 from bone marrow-derived cells suppresses neointimal formation after vascular injury in mice.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carotid Arteries; Carotid Artery Diseases; | 2006 |
Decreased plasma fibronectin leads to delayed thrombus growth in injured arterioles.
Topics: Alternative Splicing; Animals; Arterial Occlusive Diseases; Arterioles; Bleeding Time; Blood Coagula | 2006 |
P2X1 stimulation promotes thrombin receptor-mediated platelet aggregation.
Topics: Animals; Blood Platelets; Chlorides; Ferric Compounds; Humans; Lasers; Mice; Platelet Aggregation; P | 2006 |
Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets.
Topics: Amino Acid Motifs; Animals; Antibodies; Bleeding Time; Blood Platelets; Carotid Artery Diseases; Chl | 2006 |
Increased venous versus arterial thrombosis in the Factor V Leiden mouse.
Topics: Amino Acid Substitution; Animals; Arginine; Arterial Occlusive Diseases; Arteries; Chlorides; Diseas | 2007 |
Quantification of platelet composition in experimental venous thrombosis by real-time polymerase chain reaction.
Topics: Animals; Blood Platelets; Chemokine CCL2; Chlorides; Disease Models, Animal; Ferric Compounds; Gene | 2007 |
Assessing the therapeutic and toxicological effects of cesium chloride following administration to nude mice bearing PC-3 or LNCaP prostate cancer xenografts.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cesium; Chlorid | 2007 |
Genetic strain differences in platelet aggregation and thrombus formation of laboratory rats.
Topics: Adenosine Diphosphate; Animals; Arteriovenous Shunt, Surgical; Bleeding Time; Blood Platelets; Chlor | 2007 |
Experimental arterial thrombosis regulated by androgen and its receptor via modulation of platelet activation.
Topics: 6-Ketoprostaglandin F1 alpha; Androgens; Animals; Arteries; Castration; Chlorides; Dihydrotestostero | 2007 |
Diminished thrombus formation and alleviation of myocardial infarction and reperfusion injury through antibody- or small-molecule-mediated inhibition of selectin-dependent platelet functions.
Topics: Animals; Antibodies, Monoclonal; Arterial Occlusive Diseases; Chlorides; Drug Evaluation, Preclinica | 2007 |
A recombinant protein and a chemically synthesized peptide containing the active peptides of the platelet collagen receptors inhibit ferric chloride-induced thrombosis in a rat model.
Topics: Animals; Base Sequence; Chlorides; Collagen Type I; Collagen Type III; DNA Primers; Ferric Compounds | 2007 |
The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation.
Topics: Amino Acid Substitution; Anemia; Animals; Blood Platelets; Chlorides; Contractile Proteins; Ferric C | 2007 |
Factor V Leiden mutation is associated with enhanced arterial thrombotic tendency in lean but not in obese mice.
Topics: Animal Feed; Animals; Arteries; Body Weight; Chlorides; Factor V; Ferric Compounds; Genotype; Homozy | 2007 |
Role of murine integrin alpha2beta1 in thrombus stabilization and embolization: contribution of thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Chlorides; Col | 2007 |
Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo.
Topics: Animals; Arterioles; Blood Platelets; Chlorides; Cytoplasm; Ferric Compounds; Flow Cytometry; Integr | 2007 |
Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice.
Topics: Adenosine Triphosphate; Animals; beta-Thromboglobulin; Blood Platelets; Chlorides; Ferric Compounds; | 2008 |
GSK3beta is a negative regulator of platelet function and thrombosis.
Topics: Animals; Blood Platelets; Carotid Artery Injuries; Chlorides; Disease Models, Animal; Enzyme Inhibit | 2008 |
Obesity promotes injury induced femoral artery thrombosis in mice.
Topics: Animals; Antithrombins; Blood Coagulation; Body Weight; Chlorides; Factor V; Femoral Artery; Ferric | 2008 |
Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis.
Topics: Animals; Anticoagulants; Arteriovenous Shunt, Surgical; Binding Sites; Bleomycin; Blood Coagulation; | 2008 |
Cigarette smoke exposure promotes arterial thrombosis and vessel remodeling after vascular injury in apolipoprotein E-deficient mice.
Topics: Actins; Animals; Apolipoproteins E; Apoptosis; Carotid Artery Diseases; Cell Proliferation; Cells, C | 2008 |
Lipopolysaccharide augments venous and arterial thrombosis in the mouse.
Topics: Animals; Arteries; Carotid Artery Thrombosis; Chlorides; Disease Models, Animal; Dose-Response Relat | 2008 |
Prediction of the therapeutic index of marketed anti-coagulants and anti-platelet agents by guinea pig models of thrombosis and hemostasis.
Topics: Animals; Anticoagulants; Arginine; Arteriovenous Shunt, Surgical; Aspirin; Bleeding Time; Chlorides; | 2008 |
Electron and light microscopic observations on experimental thrombosis.
Topics: Animals; Blood Coagulation; Blood Platelets; Chlorides; Cytoplasmic Granules; Ear; Female; Fibrin; I | 1966 |
Antithrombotic therapy with ticlopidine in chronic renal failure patients on maintenance hemodialysis--a multicenter collaborative double blind study.
Topics: Adult; Aged; Blood Urea Nitrogen; Chlorides; Creatinine; Double-Blind Method; Female; Fibrinolytic A | 1980 |
[Calcitonin gene-related peptide and thrombolysis].
Topics: Animals; Calcitonin Gene-Related Peptide; Chlorides; Female; Ferric Compounds; Humans; Male; Middle | 1993 |
Thrombogenicity of small-diameter prosthetic grafts: relative contributions of graft-associated thrombin and factor Xa.
Topics: Adsorption; Animals; Barium Compounds; Blood Coagulation; Blood Vessel Prosthesis; Chlorides; Collag | 1997 |
L-374,087, an efficacious, orally bioavailable, pyridinone acetamide thrombin inhibitor.
Topics: Administration, Oral; Animals; Anticoagulants; Biological Availability; Chlorides; Crystallography, | 1998 |
Inhibition of arterial thrombus formation by ApoA1 Milano.
Topics: Animals; Aorta, Abdominal; Aortic Diseases; Apolipoprotein A-I; Chlorides; Cholesterol; Cholesterol, | 1999 |
Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban.
Topics: Amino Acid Sequence; Animals; Arginine; Arterial Occlusive Diseases; Arteriovenous Shunt, Surgical; | 1999 |
Demonstration of flow and platelet dependency in a ferric chloride-induced model of thrombosis.
Topics: Animals; Antifibrinolytic Agents; Antithrombins; Arterial Occlusive Diseases; Aspirin; Blood Platele | 1999 |
Plasminogen activator inhibitor-1 is a major determinant of arterial thrombolysis resistance.
Topics: Animals; Blood Platelets; Carotid Arteries; Carotid Stenosis; Chlorides; Ferric Compounds; Genetic P | 1999 |
Z-335, a new thromboxane A(2) receptor antagonist, prevents arterial thrombosis induced by ferric chloride in rats.
Topics: Administration, Oral; Animals; Aorta, Abdominal; Chlorides; Cilostazol; Dose-Response Relationship, | 2000 |
Plasminogen activator inhibitor-1 and its cofactor vitronectin stabilize arterial thrombi after vascular injury in mice.
Topics: Actins; Animals; Blood Circulation; Carotid Arteries; Carotid Artery Injuries; Chlorides; Female; Fe | 2001 |
Plasminogen activator inhibitor type 1 enhances neointima formation after oxidative vascular injury in atherosclerosis-prone mice.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Carotid Artery Injuries; Carotid Artery, Common; Cell | 2001 |
Variable protection of beta 3-integrin--deficient mice from thrombosis initiated by different mechanisms.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Blood Platelets; Carotid Artery Thrombosis; Chlorides | 2001 |
Characterization of a mouse model for thrombomodulin deficiency.
Topics: Animals; Blood Coagulation; Carotid Artery Thrombosis; Chlorides; Cytokines; Ferric Compounds; Fibri | 2001 |
Magnesium inhibits arterial thrombi after vascular injury in rat: in vivo impairment of coagulation.
Topics: Animals; Blood Coagulation Tests; Carotid Arteries; Chlorides; Disease Models, Animal; Dose-Response | 2001 |
CD40L stabilizes arterial thrombi by a beta3 integrin--dependent mechanism.
Topics: Animals; Arterioles; Blood Platelets; CD40 Ligand; Cell Adhesion; Chlorides; Ferric Compounds; Hemod | 2002 |
Chronic renal vein thrombosis.
Topics: Adolescent; Adult; Aged; Angiography; Bicarbonates; Biopsy; Chlorides; Chronic Disease; Female; Fibr | 1977 |
[Comparison of the thrombogenic properties of vascular wall after exposure to different lasers].
Topics: Animals; Argon; Carotid Arteries; Chlorides; Dogs; Femoral Artery; In Vitro Techniques; Lasers; Neod | 1987 |
[Animal experimental studies on a protease from Aspergillus ochraceus].
Topics: Animals; Aspergillus; Barium; Blood Pressure; Carbachol; Carotid Arteries; Chlorides; Female; Heart; | 1974 |
Thrombohemorrhagic lesions induced by combined treatment with rare earth metals and epinephrine.
Topics: Animals; Anticoagulants; Chlorides; Dicumarol; Epinephrine; Female; Hemorrhage; Histamine H1 Antagon | 1966 |
The surface bonded, covalently crosslinked urokinase synthetic surface. In vitro and chronic in vivo studies.
Topics: Animals; Aorta, Abdominal; Biocompatible Materials; Blood Coagulation; Blood Vessel Prosthesis; Carb | 1973 |
[Comparative animal experiments with unprepared, siliconized, and "heparin-soaked" PVC venous catheters].
Topics: Animals; Catheterization; Chlorides; Heparin; Polyvinyls; Rabbits; Silicones; Thrombosis; Time Facto | 1974 |
Isolation of a chemical trigger for thrombosis.
Topics: Animals; Arachidonic Acids; Aspirin; Bromine; Carbon Radioisotopes; Chlorides; Chromatography, Thin | 1974 |
[Pancreas transplantations. Results of a personal series].
Topics: Amylases; Angiography; Animals; Bicarbonates; Blood Glucose; Chlorides; Diabetes Mellitus; Duodenum; | 1969 |
The role of betahistine hydrochloride in the treatment of peripheral vascular arterial disease.
Topics: Adult; Aged; Amine Oxidase (Copper-Containing); Arteriosclerosis; Betahistine; Chlorides; Diabetic A | 1971 |
Function of replanted ileac segments in the dog.
Topics: Aged; Animals; Chlorides; Dogs; Gastrointestinal Motility; Humans; Ileum; Intestinal Absorption; Int | 1971 |
[Revascularization of the ischaemic kidney by implantation of the splenic artery and vein into the renal parenchyma. Radiological, functional and morphological findings].
Topics: Animals; Blood Urea Nitrogen; Chlorides; Creatinine; Dogs; Ischemia; Kidney; Ligation; Nephrectomy; | 1970 |
Predisposition to thrombosis not reflected by the blood coagulogram.
Topics: Animals; Blood Coagulation; Blood Coagulation Tests; Chlorides; Epinephrine; Rats; Scandium; Thrombo | 1966 |