chlorine has been researched along with Batten Turner Congenital Myopathy in 19 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myotonia congenita is a genetic condition that is caused by mutations in the muscle chloride channel gene CLCN1 and characterized by delayed muscle relaxation and muscle stiffness." | 1.38 | Disease-causing mutations C277R and C277Y modify gating of human ClC-1 chloride channels in myotonia congenita. ( Becher, T; Begemann, B; Fahlke, C; Fischer, M; Jurkat-Rott, K; Lehmann-Horn, F; Sternberg, D; Weinberger, S; Wojciechowski, D, 2012) |
| "We report here a family with myotonia congenita characterized by muscle stiffness and clinical and electrophysiologic myotonic phenomena transmitted in an autosomal dominant pattern." | 1.38 | Dominantly inherited myotonia congenita resulting from a mutation that increases open probability of the muscle chloride channel CLC-1. ( Chen, TY; Lee, TT; Maselli, RA; Richman, DP; Tang, CY; Tseng, PY; Yu, WP; Yu, Y, 2012) |
| "The cause of increased excitability in autosomal dominant myotonia congenita (MyC) was studied in resealed greater than 3-cm long segments of muscle fibres from eight patients." | 1.28 | Altered sodium channel behaviour causes myotonia in dominantly inherited myotonia congenita. ( Franke, C; Hatt, H; Iaizzo, PA; Lehmann-Horn, F; Ricker, K; Rüdel, R; Spittelmeister, W, 1991) |
| "1." | 1.26 | Action potentials reconstructed in normal and myotonic muscle fibres. ( Adrian, RH; Marshall, MW, 1976) |
| "The muscle membrane in myotonia congenita is characterized by a normal resting potential with a greatly increased resting resistance usually attributed to a decrease in membrane chloride permeability (PC1)." | 1.25 | Myotonia. An evaluation of the chloride hypothesis. ( Barchi, RL, 1975) |
| "Muscle from patients with myotonia congenita differed significantly (0." | 1.25 | Cable parameters, sodium, potassium, chloride, and water content, and potassium efflux in isolated external intercostal muscle of normal volunteers and patients with myotonia congenita. ( Bryant, SH; Lipicky, RJ; Salmon, JH, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (68.42) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Altamura, C | 2 |
| Desaphy, JF | 2 |
| Conte, D | 1 |
| De Luca, A | 1 |
| Imbrici, P | 2 |
| Hoppe, K | 1 |
| Chaiklieng, S | 1 |
| Lehmann-Horn, F | 5 |
| Jurkat-Rott, K | 2 |
| Wearing, S | 1 |
| Klingler, W | 1 |
| Portaro, S | 1 |
| Licata, N | 1 |
| Camerino, GM | 1 |
| Musumeci, O | 1 |
| Rodolico, C | 1 |
| Conte Camerino, D | 1 |
| Toscano, A | 1 |
| Weinberger, S | 1 |
| Wojciechowski, D | 1 |
| Sternberg, D | 1 |
| Becher, T | 1 |
| Begemann, B | 1 |
| Fahlke, C | 1 |
| Fischer, M | 1 |
| Richman, DP | 1 |
| Yu, Y | 1 |
| Lee, TT | 1 |
| Tseng, PY | 1 |
| Yu, WP | 1 |
| Maselli, RA | 1 |
| Tang, CY | 1 |
| Chen, TY | 1 |
| Birnberger, KL | 1 |
| Klepzig, M | 1 |
| Barchi, RL | 2 |
| Adrian, RH | 2 |
| Marshall, MW | 1 |
| Bryant, SH | 5 |
| Camerino, D | 1 |
| Iaizzo, PA | 1 |
| Franke, C | 1 |
| Hatt, H | 1 |
| Spittelmeister, W | 1 |
| Ricker, K | 2 |
| Rüdel, R | 4 |
| Senges, J | 1 |
| Lipicky, RJ | 3 |
| Salmon, JH | 1 |
| McComas, AJ | 1 |
| Mrozek, K | 1 |
2 reviews available for chlorine and Batten Turner Congenital Myopathy
| Article | Year |
|---|---|
Skeletal muscle ClC-1 chloride channels in health and diseases.
Topics: Animals; Chloride Channels; Chlorides; Humans; Muscle, Skeletal; Myotonia Congenita | 2020 |
Membrane changes in cells from myotonia patients.
Topics: Action Potentials; Adenosine Triphosphatases; Anthracenes; Chlorides; Electromyography; Environment; | 1985 |
17 other studies available for chlorine and Batten Turner Congenital Myopathy
| Article | Year |
|---|---|
Preclinical pharmacological in vitro investigations on low chloride conductance myotonia: effects of potassium regulation.
Topics: Animals; Chloride Channels; Chlorides; KCNQ Potassium Channels; Large-Conductance Calcium-Activated | 2020 |
Clinical, Molecular, and Functional Characterization of CLCN1 Mutations in Three Families with Recessive Myotonia Congenita.
Topics: Adult; Cell Line; Chloride Channels; Chlorides; Consanguinity; Conserved Sequence; Exons; Female; Ge | 2015 |
Disease-causing mutations C277R and C277Y modify gating of human ClC-1 chloride channels in myotonia congenita.
Topics: Adult; Chloride Channels; Chlorides; Female; HEK293 Cells; Humans; Ion Channel Gating; Male; Middle | 2012 |
Dominantly inherited myotonia congenita resulting from a mutation that increases open probability of the muscle chloride channel CLC-1.
Topics: Adult; Animals; Child; Chloride Channels; Chlorides; Disease Progression; Female; Genes, Dominant; H | 2012 |
Influence of extracellular potassium and intracellular pH on myotonia.
Topics: Animals; Chlorides; Electric Stimulation; Extracellular Space; Hydrogen-Ion Concentration; Intracell | 1979 |
Muscle membrane chloride conductance and the myotonic syndromes.
Topics: Animals; Anthracenes; Calcium; Carboxylic Acids; Chickens; Chlorides; Goats; Humans; Myotonia; Myoto | 1978 |
Action potentials reconstructed in normal and myotonic muscle fibres.
Topics: Action Potentials; Animals; Chlorides; Electric Stimulation; Goats; Kinetics; Models, Biological; Mu | 1976 |
Myotonia. An evaluation of the chloride hypothesis.
Topics: Action Potentials; Animals; Anura; Biological Transport; Cell Membrane Permeability; Chlorides; Goat | 1975 |
Chloride conductance of denervated gastrocnemius fibers from normal goats.
Topics: Action Potentials; Animals; Chlorides; Goats; In Vitro Techniques; Membrane Potentials; Motor Neuron | 1976 |
Altered sodium channel behaviour causes myotonia in dominantly inherited myotonia congenita.
Topics: Action Potentials; Adult; Chlorides; Female; Genes, Dominant; Humans; In Vitro Techniques; Male; Mic | 1991 |
Membrane defects in paramyotonia congenita (Eulenburg).
Topics: Biopsy; Cell Membrane Permeability; Chlorides; Cold Temperature; Humans; In Vitro Techniques; Interc | 1987 |
Mammalian skeletal muscle: reduced chloride conductance in drug-induced myotonia and induction of myotonia by low-chloride solution.
Topics: Action Potentials; Animals; Chlorides; Cholesterol; Diaphragm; Diazonium Compounds; Electric Stimula | 1972 |
On the repetitive discharge in myotonic muscle fibres.
Topics: Action Potentials; Animals; Biological Transport, Active; Chlorides; Electrophysiology; Glycerol; Go | 1974 |
Cable parameters, sodium, potassium, chloride, and water content, and potassium efflux in isolated external intercostal muscle of normal volunteers and patients with myotonia congenita.
Topics: Action Potentials; Adult; Biological Transport; Biopsy; Chlorides; Extracellular Space; Female; Huma | 1971 |
Ion content, potassium efflux and cable properties of myotonic, human, external-intercostal muscle.
Topics: Action Potentials; Cell Membrane Permeability; Chlorides; Extracellular Space; Humans; Membrane Pote | 1971 |
The electrical properties of muscle fiber membranes in dystrophia myotonica and myotonia congenita.
Topics: Action Potentials; Adult; Cell Membrane Permeability; Chlorides; Electric Conductivity; Electric Sti | 1968 |
Sodium, potassium, and chloride fluxes in intercostal muscle from normal goats and goats with hereditary myotonia.
Topics: Animals; Anura; Biological Transport; Cell Membrane Permeability; Chlorides; Electrophysiology; Fema | 1966 |