Page last updated: 2024-10-17

chlorine and Aura

chlorine has been researched along with Aura in 137 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Research Excerpts

ExcerptRelevanceReference
" The dog was successfully treated for idiopathic epilepsy since the age of 1-year-old with phenobarbital and potassium bromide."8.02Bromide toxicosis (bromism) secondary to a decreased chloride intake after dietary transition in a dog with idiopathic epilepsy: a case report. ( Debreuque, M; Fantinati, M; Priymenko, N, 2021)
"Taken together, these results confirmed that vitexin effectively alleviates epilepsy susceptibility through inhibition of inflammation along with improved BBB integrity."7.88Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1. ( Han, S; He, XH; Huang, WX; Liu, WH; Luo, WD; Min, JW; Peng, BW; Peng, YY; Wang, X; Yin, J, 2018)
" This study is to examine the potential epilepsy control effect of deferoxamine (DFO), an iron chelator, on a ferric chloride-induced epilepsy rat model."7.85Effectiveness of deferoxamine on ferric chloride-induced epilepsy in rats. ( Cai, S; Chen, L; Jiang, S; Shi, Y; Wu, Z; Zhu, R; Zou, X, 2017)
" In this study, we aimed to investigate the long-term expression profiles of NKCC1 and KCC2 in CA1 region in the mice model of lithium-pilocarpine induced status epilepticus (PISE) and their relationship with epileptogenesis."7.74Long-term expressional changes of Na+ -K+ -Cl- co-transporter 1 (NKCC1) and K+ -Cl- co-transporter 2 (KCC2) in CA1 region of hippocampus following lithium-pilocarpine induced status epilepticus (PISE). ( Chen, S; Chen, Z; Li, X; Zhou, J; Zhou, L; Zhu, F, 2008)
"We report the case of a 12-year-old girl with severe clinically relevant hyponatremia (118 mmol/l) and hypochloremia (81 mmol/l) during treatment with oxcarbazepine (OCBZ)."7.70Hyponatremia induced by oxcarbazepine in children. ( Boenigk, HE; Borusiak, P; Holert, N; Korn-Merker, E, 1998)
"Topiramate is a recently released antiepileptic agent used in the treatment of patients with refractory seizure disorders."5.31Central hyperventilation related to administration of topiramate. ( Korn, DE; Laskey, AL; Moorjani, BI; Patel, NC; Tobias, JD, 2000)
"Phenytoin treatment prevented the occurrence of convulsive and EEG seizures; however, lipid peroxidation was unaffected (16."5.27Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy. ( Triggs, WJ; Willmore, LJ, 1984)
" The dog was successfully treated for idiopathic epilepsy since the age of 1-year-old with phenobarbital and potassium bromide."4.02Bromide toxicosis (bromism) secondary to a decreased chloride intake after dietary transition in a dog with idiopathic epilepsy: a case report. ( Debreuque, M; Fantinati, M; Priymenko, N, 2021)
"Taken together, these results confirmed that vitexin effectively alleviates epilepsy susceptibility through inhibition of inflammation along with improved BBB integrity."3.88Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1. ( Han, S; He, XH; Huang, WX; Liu, WH; Luo, WD; Min, JW; Peng, BW; Peng, YY; Wang, X; Yin, J, 2018)
" This study is to examine the potential epilepsy control effect of deferoxamine (DFO), an iron chelator, on a ferric chloride-induced epilepsy rat model."3.85Effectiveness of deferoxamine on ferric chloride-induced epilepsy in rats. ( Cai, S; Chen, L; Jiang, S; Shi, Y; Wu, Z; Zhu, R; Zou, X, 2017)
"Dehydroepiandrosterone (DHEA), a neuroactive androgen steroid, has antiepileptic action in iron-induced experimental epilepsy (which models post-traumatic clinical epilepsy)."3.79Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters. ( Mishra, M; Mukherjee, S; Sharma, D; Singh, R, 2013)
"Although bromide (Br) is used to treat intractable epilepsy, serum Br concentrations are not routinely analyzed."3.77Differences in automated analyzers for assessing the use of imprecise serum chloride concentrations as indirect predictors of serum bromide concentrations. ( Fukuda, M; Ishii, E; Kikuchi, C; Motoki, T; Ohmori, H; Okamoto, K; Suemaru, K; Suzuki, Y; Wakamoto, H, 2011)
"Topiramate, which is commonly prescribed for seizure disorders and migraine prophylaxis, sometimes causes metabolic acidosis and hypokalemia."3.76Chronic impact of topiramate on acid-base balance and potassium in childhood. ( Belotti, EA; Bianchetti, MG; Pifferini, R; Ragazzi, M; Ramelli, GP; Simonetti, GD; Taddeo, I, 2010)
" In this study, we aimed to investigate the long-term expression profiles of NKCC1 and KCC2 in CA1 region in the mice model of lithium-pilocarpine induced status epilepticus (PISE) and their relationship with epileptogenesis."3.74Long-term expressional changes of Na+ -K+ -Cl- co-transporter 1 (NKCC1) and K+ -Cl- co-transporter 2 (KCC2) in CA1 region of hippocampus following lithium-pilocarpine induced status epilepticus (PISE). ( Chen, S; Chen, Z; Li, X; Zhou, J; Zhou, L; Zhu, F, 2008)
" Of the various methods used for inducing experimental epileptic models, the intracortical administration of ferric chloride (FeCl(3)) into sensorimotor cortex induces recurrent seizures and epileptic discharge similar to human post-traumatic epilepsy through the generation of free radicals."3.74Inhibitory role of Acorus calamus in ferric chloride-induced epileptogenesis in rat. ( Guha, D; Hazra, R; Ray, K, 2007)
"We report the case of a 12-year-old girl with severe clinically relevant hyponatremia (118 mmol/l) and hypochloremia (81 mmol/l) during treatment with oxcarbazepine (OCBZ)."3.70Hyponatremia induced by oxcarbazepine in children. ( Boenigk, HE; Borusiak, P; Holert, N; Korn-Merker, E, 1998)
"Bromide treatment was successful in controlling seizures in an 11-year-old Dachshund with epilepsy and presumptive phenobarbital-associated hepatopathy."3.69High dietary chloride content associated with loss of therapeutic serum bromide concentrations in an epileptic dog. ( Center, SA; Garland, S; Shaw, N; Trepanier, LA, 1996)
"The effects of Guilingji, an antiaging prescription comprised of traditional Chinese medicinal herbs and animal components, on the brain level of thiobarbituric acid reactive substances (TBARS) and superoxide dismutase (SOD) activity in the brain of rats with FeCl3-induced epilepsy were examined with fluorophotometry and electron spin resonance (ESR) spectrometry, respectively."3.68Antioxidant action of guilingji in the brain of rats with FeCl3-induced epilepsy. ( Edamatsu, R; Kabuto, H; Liu, J; Mori, A, 1990)
"Epilepsy is a neurological disease characterized by abnormal or synchronous brain activity causing seizures, which may produce convulsions, minor physical signs, or a combination of symptoms."2.82Molecular Mechanisms of Epilepsy: The Role of the Chloride Transporter KCC2. ( Belperio, G; Corso, C; Duarte, CB; Mele, M, 2022)
"The antiseizure properties of benzodiazepines are mediated by γ-aminobutyric acid type A (GABA(A) ) receptors."2.48Possible alterations in GABAA receptor signaling that underlie benzodiazepine-resistant seizures. ( Deeb, TZ; Maguire, J; Moss, SJ, 2012)
"In animal experiments, seizures were found to increase NKCC1 expression, lower the KCC2 expression and accelerate neuronal differentiation."2.47Alterations in the expression of neuronal chloride transporters may contribute to schizophrenia. ( Kalkman, HO, 2011)
"The causes of epilepsies and epileptic seizures are multifactorial."2.46Mutations affecting GABAergic signaling in seizures and epilepsy. ( Galanopoulou, AS, 2010)
"Angelman syndrome is a neurodevelopmental disorder caused by loss of function of the maternally expressed UBE3A gene."1.91Imbalanced expression of cation-chloride cotransporters as a potential therapeutic target in an Angelman syndrome mouse model. ( Egawa, K; Fukuda, A; Nishio, S; Sato, D; Shiraishi, H; Takahashi, Y; Watanabe, M, 2023)
"In most witnessed cases of SUDEP generalized seizures and respiratory failure preceded death, and pre-mortem neuroimaging studies in SUDEP patients observed changes in specific subcortical structures."1.46Specific subcortical structures are activated during seizure-induced death in a model of sudden unexpected death in epilepsy (SUDEP): A manganese-enhanced magnetic resonance imaging study. ( Brozoski, TJ; Faingold, CL; Kommajosyula, SP; Odintsov, BM; Randall, ME, 2017)
"Brain gliomas are highly epileptogenic."1.40Cortical GABAergic excitation contributes to epileptic activities around human glioma. ( Baulac, M; Bielle, F; Capelle, L; Chazal, G; Cresto, N; Devaux, B; Duyckaerts, C; Huberfeld, G; Kourdougli, N; Le Van Quyen, M; Miles, R; Pallud, J; Pellegrino, C; Rivera, C; Varlet, P, 2014)
"Focal cortical dysplasia (FCD), which is characterized histologically by disorganized cortical lamination and large abnormal cells, is one of the major causes of intractable epilepsies."1.37KCC2 was downregulated in small neurons localized in epileptogenic human focal cortical dysplasia. ( Fujiwara, T; Fukuda, A; Inoue, Y; Matsuda, K; Mihara, T; Okabe, A; Sato, K; Shimizu-Okabe, C; Tanaka, M; Yagi, K, 2011)
"The clinic treatment of epilepsy with epileptic foci overlapped with eloquent cortex is not satisfactory."1.35Low- and high-frequency electric cortical stimulation suppress the ferric chloride-induced seizures in rats. ( Gao, GD; Guo, H; Jing, XR; Wang, HW; Yao, QH; Zhang, H, 2008)
"Occurrence of spontaneous epileptic seizures was analyzed at 2 months post-SE using continuous video-EEG monitoring."1.35Manganese enhanced MRI detects mossy fiber sprouting rather than neurodegeneration, gliosis or seizure-activity in the epileptic rat hippocampus. ( Einula, C; Gröhn, OH; Immonen, RJ; Kharatishvili, I; Pitkänen, A; Sierra, A, 2008)
"Topiramate (TPM) is an anticonvulsant whose impact on firing activity and intracellular pH (pHi) regulation of CA3 neurons was investigated."1.32Topiramate modulates pH of hippocampal CA3 neurons by combined effects on carbonic anhydrase and Cl-/HCO3- exchange. ( Leniger, T; Thöne, J; Wiemann, M, 2004)
"Topiramate is a recently released antiepileptic agent used in the treatment of patients with refractory seizure disorders."1.31Central hyperventilation related to administration of topiramate. ( Korn, DE; Laskey, AL; Moorjani, BI; Patel, NC; Tobias, JD, 2000)
"Vanillyl alcohol (VA) is a component of Gastrodia elata Bl."1.31Anticonvulsive and free radical scavenging activities of vanillyl alcohol in ferric chloride-induced epileptic seizures in Sprague-Dawley rats. ( Chang, CH; Chiang, SY; Hsieh, CL; Hsieh, CT; Li, TC; Lin, JG; Pon, CZ; Tang, NY, 2000)
"With acute seizures, at +5 days after the injection, levels of GluR1, NMDAR1, and NMDAR2 were markedly increased in both hippocampi, with quantities at least 2-4 times baseline."1.31Sequential changes in AMPA and NMDA protein levels during Fe(3+)-induced epileptogenesis. ( Doi, T; Mitsuyama, Y; Tokumaru, J; Ueda, Y; Willmore, LJ, 2001)
"In audiogenic seizure mice, glial CA activity is increased and glial anion transport is reduced."1.27Ionic and acid-base regulation of neurons and glia during seizures. ( Chen, CF; Chow, SY; Engstrom, FL; Kemp, JW; White, HS; Woodbury, DM, 1984)
"Phenytoin treatment prevented the occurrence of convulsive and EEG seizures; however, lipid peroxidation was unaffected (16."1.27Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy. ( Triggs, WJ; Willmore, LJ, 1984)

Research

Studies (137)

TimeframeStudies, this research(%)All Research%
pre-199040 (29.20)18.7374
1990's20 (14.60)18.2507
2000's40 (29.20)29.6817
2010's23 (16.79)24.3611
2020's14 (10.22)2.80

Authors

AuthorsStudies
Belperio, G1
Corso, C1
Duarte, CB1
Mele, M1
Aussel, A1
Ranta, R1
Aron, O1
Colnat-Coulbois, S1
Maillard, L1
Buhry, L1
Lopez-Sola, E1
Sanchez-Todo, R1
Lleal, È1
Köksal-Ersöz, E1
Yochum, M1
Makhalova, J1
Mercadal, B1
Guasch-Morgades, M1
Salvador, R1
Lozano-Soldevilla, D1
Modolo, J1
Bartolomei, F1
Wendling, F1
Benquet, P1
Ruffini, G1
Josiah, SS1
Meor Azlan, NF1
Oguro-Ando, A1
Zhang, J2
Lam, P1
Newland, J1
Faull, RLM1
Kwakowsky, A1
Egawa, K1
Watanabe, M2
Shiraishi, H2
Sato, D1
Takahashi, Y1
Nishio, S1
Fukuda, A4
Perucca, E2
Bialer, M1
White, HS2
Auer, T1
Schreppel, P1
Erker, T1
Schwarzer, C1
Mavrovic, M1
Uvarov, P2
Delpire, E1
Vutskits, L1
Kaila, K3
Puskarjov, M1
Akita, T1
Garneau, AP1
Slimani, S1
Fiola, MJ1
Tremblay, LE1
Isenring, P1
Virtanen, MA1
Hübner, CA1
Menzikov, SA1
Morozov, SG1
Kubatiev, AA1
Fantinati, M1
Priymenko, N1
Debreuque, M1
Kommajosyula, SP1
Randall, ME1
Brozoski, TJ1
Odintsov, BM1
Faingold, CL1
Luo, WD1
Min, JW1
Huang, WX1
Wang, X1
Peng, YY1
Han, S1
Yin, J1
Liu, WH1
He, XH1
Peng, BW1
Wang, Y2
Chen, Z2
Chizhov, AV1
Amakhin, DV1
Zaitsev, AV1
Tillman, L1
Mishra, M1
Singh, R4
Mukherjee, S1
Sharma, D1
Nakao, A1
Miki, T1
Shimono, K1
Oka, H1
Numata, T1
Kiyonaka, S1
Matsushita, K1
Ogura, H1
Niidome, T1
Noebels, JL1
Wakamori, M1
Imoto, K1
Mori, Y1
Pallud, J1
Le Van Quyen, M1
Bielle, F1
Pellegrino, C1
Varlet, P1
Cresto, N1
Baulac, M1
Duyckaerts, C1
Kourdougli, N1
Chazal, G1
Devaux, B1
Rivera, C1
Miles, R2
Capelle, L1
Huberfeld, G1
Alfonsa, H1
Merricks, EM1
Codadu, NK1
Cunningham, MO1
Deisseroth, K1
Racca, C1
Trevelyan, AJ1
Kadala, A1
Verdier, D1
Morquette, P1
Kolta, A1
Zou, X1
Jiang, S1
Wu, Z1
Shi, Y1
Cai, S1
Zhu, R1
Chen, L1
Dengler, CG1
Yue, C1
Takano, H1
Coulter, DA1
Li, X1
Zhou, J1
Chen, S1
Zhu, F1
Zhou, L1
Matsuda, Y2
Saito, N2
Yamamoto, K1
Niitsu, T1
Kogure, S2
Rebrov, IG3
Karpova, MN3
Andreev, AA3
Klishina, NY2
Kalinina, MV2
Kusnetzova, LV1
SILVER, ML5
ZEVIN, SS1
MONAHAN, EP2
KLEIN, JR1
Coull, JA1
Gagnon, M1
Planells-Cases, R1
Jentsch, TJ1
Belotti, EA1
Taddeo, I1
Ragazzi, M1
Pifferini, R1
Simonetti, GD1
Bianchetti, MG1
Ramelli, GP1
Viitanen, T1
Ruusuvuori, E1
Voipio, J1
Galanopoulou, AS1
Golden, N1
Darmadipura, S1
Bagiada, NA1
Kahle, KT3
Rinehart, J1
Lifton, RP1
Kalkman, HO1
Shimizu-Okabe, C1
Tanaka, M1
Matsuda, K1
Mihara, T1
Okabe, A2
Sato, K2
Inoue, Y1
Fujiwara, T1
Yagi, K1
Motoki, T1
Fukuda, M1
Ohmori, H1
Suemaru, K1
Okamoto, K1
Wakamoto, H1
Kikuchi, C1
Suzuki, Y1
Ishii, E1
Maa, EH1
Walcott, BP1
Spitz, MC1
Staley, KJ1
Ben-Ari, Y1
Khalilov, I1
Cherubini, E1
Deeb, TZ1
Maguire, J1
Moss, SJ1
Ohno, K1
Toyoda, H1
Yokokura, M1
Timofeev, I2
Grenier, F2
Steriade, M2
Kitayama, M1
Miyata, H1
Yano, M1
Yamauchi, T1
Ueda, Y7
Doi, T5
Tokumaru, J4
Willmore, LJ10
IVANOV, V1
MILENKOV, K1
TSOLOV, N1
ALEKSANDROVA, E1
TSANKOV, I1
MECHKUNOV, K1
KHAMAMDZHIEV, K1
BALABANOVA, V1
WADA, T1
SAKURADA, S1
OIKAWA, K1
FURUKOHRI, T1
MURAMOTO, Y1
NEUMANN, G1
Cohen, I1
Navarro, V1
Le Duigou, C1
Nakajima, A3
Kuzina, OS2
Kalinina, MS1
Abrosimov, IY1
Belykh, NP1
Leniger, T1
Thöne, J1
Wiemann, M1
de Freitas, RL1
de Oliveira, RC1
de Carvalho, AD1
Felippotti, TT1
Bassi, GS1
Elias-Filho, DH1
Coimbra, NC1
Jin, X1
Huguenard, JR1
Prince, DA1
Yao, Y1
Sun, S1
Kong, Q1
Tong, E1
Gorji, A1
Stemmer, N1
Rambeck, B1
Jürgens, U1
May, T1
Pannek, HW1
Behne, F1
Ebner, A1
Straub, H1
Speckmann, EJ1
Rossmeisl, JH1
Zimmerman, K1
Inzana, KD1
Higgins, MA1
Munakata, M1
Otsuki, T1
Nakama, H1
Arima, K1
Itoh, M1
Nabekura, J1
Iinuma, K1
Tsuchiya, S1
Muñoz, A1
Méndez, P1
DeFelipe, J1
Alvarez-Leefmans, FJ1
Kuznetsova, LV1
Fujiwara-Tsukamoto, Y1
Isomura, Y1
Imanishi, M1
Fukai, T1
Takada, M1
Nagatomo, K2
Yokoyama, H1
Takaki, M1
Obenaus, A1
Jacobs, RE1
POLLOCK, GH1
Yao, QH1
Zhang, H1
Wang, HW1
Jing, XR1
Guo, H1
Gao, GD1
Immonen, RJ1
Kharatishvili, I1
Sierra, A1
Einula, C1
Pitkänen, A1
Gröhn, OH1
Hazra, R1
Ray, K1
Guha, D1
Lux, HD2
Heinemann, U3
Woodbury, DM1
Engstrom, FL1
Chen, CF1
Kemp, JW1
Chow, SY1
Hiramatsu, M5
Kochi, H1
Mori, A8
Robitaille, Y1
Sherwin, A1
Pathak, DN1
Roy, D1
Hattori, Y2
Moriwaki, A2
Nishida, N1
Yasuhara, H1
Hori, Y2
Triggs, WJ1
Witte, OW1
Kadowaki, D1
Kinno, I1
Kadoya, K1
Hamada, H1
Edamatsu, R3
Bonnet, U1
Bingmann, D1
Shaw, N1
Trepanier, LA1
Center, SA1
Garland, S1
Kabuto, H3
Yokoi, I2
Habu, H1
Ogawa, N1
Borusiak, P1
Korn-Merker, E1
Holert, N1
Boenigk, HE1
Hochman, DW2
D'Ambrosio, R1
Janigro, D1
Schwartzkroin, PA2
Takeda, A1
Hanajima, T1
Ijiro, H1
Ishige, A1
Iizuka, S1
Okada, S1
Oku, N1
Sharma, V2
Roettger, VR1
Amara, SG1
Demir, R1
Haberly, LB1
Jackson, MB1
Mitsuyama, Y2
Xiong, ZQ1
Stringer, JL1
Laskey, AL1
Korn, DE1
Moorjani, BI1
Patel, NC1
Tobias, JD1
Matsufuji, H1
Hayashi, T1
Nishikawa, M1
Yoshitomi, T1
Ichiyama, T1
Furukawa, S1
Hsieh, CL1
Chang, CH1
Chiang, SY1
Li, TC1
Tang, NY1
Pon, CZ1
Hsieh, CT1
Lin, JG1
Komatsu, M1
Al-Noori, S1
Swann, JW1
Hochner, B1
Spira, ME1
Werman, R1
Natelson, S2
Miletich, DJ2
Seals, CF2
Visintine, DJ2
Albrecht, RF2
Jooste, PL1
Wolfswinkel, JM1
Schoeman, JJ1
Strydom, NB1
Liu, J2
Santiago, LA1
Osato, JA1
Olpe, H1
Kolb, CN1
Hausdorf, A1
Haas, HL1
Avoli, M2
Drapeau, C1
Perreault, P1
Louvel, J1
Pumain, R1
Ito, M1
Tsuda, H1
Oguro, K1
Mutoh, K1
Shirasaka, Y1
Mikawa, H1
Oliver, MW1
Miller, JJ1
Olsen, RW1
Wamsley, JK1
Lee, RJ1
Lomax, P1
Giaretta, D1
Gloor, P1
Chamberlin, NL1
Dingledine, R1
Dietzel, I2
Hayashi, Y1
Sunami, T1
Viukari, NM4
Yamamoto, C1
Gill, TH1
Young, OM1
Tower, DB1
Plum, CM1
Hankiewicz, J1
Lesniak, M1
Leksin, EN1
Osintseva, TS1
Szilágyi, AK1
Breyer, U1
Kanig, K1
Reynolds, EH1
Tammisto, P1
Barnett, IG1
Gillen, HW1
Pippinger, CE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Study on Long-term Outcome and Potential Usefulness fo an Intervention Aimed at Reducing Adverse Effects in Patients With Refractory Epilepsy[NCT03939507]1,000 participants (Actual)Interventional2006-11-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

25 reviews available for chlorine and Aura

ArticleYear
Molecular Mechanisms of Epilepsy: The Role of the Chloride Transporter KCC2.
    Journal of molecular neuroscience : MN, 2022, Volume: 72, Issue:7

    Topics: Chlorides; Epilepsy; Female; Humans; Male; Quality of Life; Receptors, GABA-A; Seizures; Symporters

2022
Cation-Chloride Cotransporters KCC2 and NKCC1 as Therapeutic Targets in Neurological and Neuropsychiatric Disorders.
    Molecules (Basel, Switzerland), 2023, Jan-31, Volume: 28, Issue:3

    Topics: Cations; Chlorides; Epilepsy; Humans; Solute Carrier Family 12, Member 2; Symporters

2023
New GABA-Targeting Therapies for the Treatment of Seizures and Epilepsy: I. Role of GABA as a Modulator of Seizure Activity and Recently Approved Medications Acting on the GABA System.
    CNS drugs, 2023, Volume: 37, Issue:9

    Topics: Animals; Anticonvulsants; Brain; Chlorides; Epilepsy; Humans; Mammals; Seizures

2023
Impaired chloride homeostasis in epilepsy: Molecular basis, impact on treatment, and current treatment approaches.
    Pharmacology & therapeutics, 2020, Volume: 205

    Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Bumetanide; Chlorides; Diuretics; Drug Development; E

2020
Intracellular Cl
    Pflugers Archiv : European journal of physiology, 2020, Volume: 472, Issue:7

    Topics: Animals; Brain; Chlorides; Epilepsy; Humans; K Cl- Cotransporters; Mutation; Neurons; Symporters

2020
Multiple Facets and Roles of Na
    Physiology (Bethesda, Md.), 2020, 11-01, Volume: 35, Issue:6

    Topics: Animals; Brain Edema; Chlorides; Epilepsy; Humans; Hypertension; Ion Transport; Pain; Potassium; Sod

2020
NKCC1, an Elusive Molecular Target in Brain Development: Making Sense of the Existing Data.
    Cells, 2020, 12-04, Volume: 9, Issue:12

    Topics: Alternative Splicing; Animals; Brain; Central Nervous System; Chlorides; Epilepsy; gamma-Aminobutyri

2020
Intricacies of GABA
    International journal of molecular sciences, 2021, Feb-01, Volume: 22, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alzheimer Disease; Animals; Anion Transport Prote

2021
Double-edged GABAergic synaptic transmission in seizures: The importance of chloride plasticity.
    Brain research, 2018, 12-15, Volume: 1701

    Topics: Animals; Chlorides; Epilepsy; GABA Agents; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; K Cl-

2018
Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K
    BioMed research international, 2019, Volume: 2019

    Topics: Central Nervous System; Chloride Channels; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Gene Target

2019
Ion Homeostasis in Rhythmogenesis: The Interplay Between Neurons and Astroglia.
    Physiology (Bethesda, Md.), 2015, Volume: 30, Issue:5

    Topics: Action Potentials; Animals; Astrocytes; Brain; Calcium; Cell Communication; Central Pattern Generato

2015
The manipulation of cation-chloride co-transporters as a novel means to treat persistent pain, epilepsy and other neurological disorders.
    Current opinion in investigational drugs (London, England : 2000), 2009, Volume: 10, Issue:1

    Topics: Animals; Cations; Chlorides; Epilepsy; Humans; K Cl- Cotransporters; Nervous System Diseases; Neuron

2009
Chloride channelopathies.
    Biochimica et biophysica acta, 2009, Volume: 1792, Issue:3

    Topics: Animals; Bestrophins; Channelopathies; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosi

2009
Mutations affecting GABAergic signaling in seizures and epilepsy.
    Pflugers Archiv : European journal of physiology, 2010, Volume: 460, Issue:2

    Topics: Angelman Syndrome; Animals; Channelopathies; Chloride Channels; Chlorides; CLC-2 Chloride Channels;

2010
Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases.
    Biochimica et biophysica acta, 2010, Volume: 1802, Issue:12

    Topics: Anemia, Sickle Cell; Animals; Caenorhabditis; Chlorides; Enzyme Activation; Epilepsy; Humans; Hypert

2010
Alterations in the expression of neuronal chloride transporters may contribute to schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Mar-30, Volume: 35, Issue:2

    Topics: Age Factors; Animals; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Humans; Mice; Neural Stem Cells;

2011
Diuretics and epilepsy: will the past and present meet?
    Epilepsia, 2011, Volume: 52, Issue:9

    Topics: Amino Acid Transport Systems, Basic; Animals; Animals, Newborn; Anticonvulsants; Cerebral Cortex; Ch

2011
The GABA excitatory/inhibitory shift in brain maturation and neurological disorders.
    The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2012, Volume: 18, Issue:5

    Topics: Animals; Anticonvulsants; Brain; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Humans; Nervous Syste

2012
Possible alterations in GABAA receptor signaling that underlie benzodiazepine-resistant seizures.
    Epilepsia, 2012, Volume: 53 Suppl 9

    Topics: Animals; Anticonvulsants; Benzodiazepines; Chlorides; Drug Resistance; Epilepsy; GABA Modulators; Ho

2012
Mesial temporal lobe epilepsy: a pathological replay of developmental mechanisms?
    Biology of the cell, 2003, Volume: 95, Issue:6

    Topics: Animals; Brain; Chlorides; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobut

2003
An introduction to antiepileptic drugs.
    Epilepsia, 2005, Volume: 46 Suppl 4

    Topics: Adult; Anticonvulsants; Biological Availability; Calcium Channels; Chlorides; Drug Interactions; Dru

2005
Magnetic resonance imaging of functional anatomy: use for small animal epilepsy models.
    Epilepsia, 2007, Volume: 48 Suppl 4

    Topics: Animals; Anisotropy; Axons; Biological Transport; Brain; Brain Mapping; Chlorides; Diffusion Magneti

2007
GABA and glutamate transporters: therapeutic and etiologic implications for epilepsy.
    Advances in neurology, 1999, Volume: 79

    Topics: Amino Acid Transport System X-AG; Amino Acid Transport Systems; Animals; ATP-Binding Cassette Transp

1999
Benzodiazepine/barbiturate/GABA receptor-chloride ionophore complex in a genetic model for generalized epilepsy.
    Advances in neurology, 1986, Volume: 44

    Topics: Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Binding Sites; Chlorides; Disease Models, A

1986
Ionic changes and alterations in the size of the extracellular space during epileptic activity.
    Advances in neurology, 1986, Volume: 44

    Topics: Action Potentials; Aluminum Oxide; Animals; Chlorides; Epilepsy; Extracellular Space; Forecasting; H

1986

Other Studies

112 other studies available for chlorine and Aura

ArticleYear
Cell to network computational model of the epileptic human hippocampus suggests specific roles of network and channel dysfunctions in the ictal and interictal oscillations.
    Journal of computational neuroscience, 2022, Volume: 50, Issue:4

    Topics: Chlorides; Electroencephalography; Epilepsy; Hippocampus; Humans; Models, Neurological; Potassium; S

2022
A personalizable autonomous neural mass model of epileptic seizures.
    Journal of neural engineering, 2022, 09-06, Volume: 19, Issue:5

    Topics: Chlorides; Electroencephalography; Epilepsy; Humans; Pyramidal Cells; Seizures

2022
Study of the Functions and Activities of Neuronal K-Cl Co-Transporter KCC2 Using Western Blotting.
    Journal of visualized experiments : JoVE, 2022, 12-09, Issue:190

    Topics: Blotting, Western; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Humans; Neurons; Symporters

2022
Imbalanced expression of cation-chloride cotransporters as a potential therapeutic target in an Angelman syndrome mouse model.
    Scientific reports, 2023, 04-17, Volume: 13, Issue:1

    Topics: Angelman Syndrome; Animals; Bumetanide; Chlorides; Epilepsy; Mice; Receptors, GABA-A; Sodium-Potassi

2023
Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons.
    EMBO reports, 2020, 04-03, Volume: 21, Issue:4

    Topics: Apoptosis; Chlorides; Epilepsy; Humans; Neurons; Symporters

2020
Bromide toxicosis (bromism) secondary to a decreased chloride intake after dietary transition in a dog with idiopathic epilepsy: a case report.
    BMC veterinary research, 2021, Jul-22, Volume: 17, Issue:1

    Topics: Animals; Anticonvulsants; Bromides; Chlorides; Diet; Dog Diseases; Dogs; Epilepsy; Male; Potassium C

2021
Specific subcortical structures are activated during seizure-induced death in a model of sudden unexpected death in epilepsy (SUDEP): A manganese-enhanced magnetic resonance imaging study.
    Epilepsy research, 2017, Volume: 135

    Topics: Acoustic Stimulation; Animals; Brain; Chlorides; Contrast Media; Death, Sudden; Disease Models, Anim

2017
Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1.
    Journal of neuroinflammation, 2018, Jun-20, Volume: 15, Issue:1

    Topics: Animals; Animals, Newborn; Anticonvulsants; Apigenin; Cell Hypoxia; Cells, Cultured; Chlorides; Cyto

2018
Mathematical model of Na-K-Cl homeostasis in ictal and interictal discharges.
    PloS one, 2019, Volume: 14, Issue:3

    Topics: Action Potentials; Animals; Chlorides; Computer Simulation; Entorhinal Cortex; Epilepsy; Hippocampus

2019
Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters.
    Epilepsy research, 2013, Volume: 106, Issue:1-2

    Topics: Amino Acid Transport System X-AG; Animals; Anticonvulsants; Chlorides; Dehydroepiandrosterone; Elect

2013
Compromised maturation of GABAergic inhibition underlies abnormal network activity in the hippocampus of epileptic Ca2+ channel mutant mice, tottering.
    Pflugers Archiv : European journal of physiology, 2015, Volume: 467, Issue:4

    Topics: Action Potentials; Animals; CA3 Region, Hippocampal; Calcium Channels, N-Type; Cells, Cultured; Chlo

2015
Cortical GABAergic excitation contributes to epileptic activities around human glioma.
    Science translational medicine, 2014, Jul-09, Volume: 6, Issue:244

    Topics: Action Potentials; Brain Neoplasms; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Glioma; Glutamates

2014
The contribution of raised intraneuronal chloride to epileptic network activity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, May-20, Volume: 35, Issue:20

    Topics: 4-Aminopyridine; Action Potentials; Animals; Cells, Cultured; Chlorides; Epilepsy; Extracellular Spa

2015
Effectiveness of deferoxamine on ferric chloride-induced epilepsy in rats.
    Brain research, 2017, 03-01, Volume: 1658

    Topics: Animals; Anticonvulsants; Blotting, Western; Brain; Chlorides; Deferoxamine; Disease Models, Animal;

2017
Massively augmented hippocampal dentate granule cell activation accompanies epilepsy development.
    Scientific reports, 2017, 02-20, Volume: 7

    Topics: Animals; Chlorides; Dentate Gyrus; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Glutam

2017
Long-term expressional changes of Na+ -K+ -Cl- co-transporter 1 (NKCC1) and K+ -Cl- co-transporter 2 (KCC2) in CA1 region of hippocampus following lithium-pilocarpine induced status epilepticus (PISE).
    Brain research, 2008, Jul-24, Volume: 1221

    Topics: Animals; Chloride Channels; Chlorides; Disease Models, Animal; Epilepsy; Gene Expression Regulation;

2008
Effects of the Ih blockers CsCl and ZD7288 on inherited epilepsy in Mongolian gerbils.
    Experimental animals, 2008, Volume: 57, Issue:4

    Topics: Animals; Cardiotonic Agents; Cesium; Chlorides; Cyclic Nucleotide-Gated Cation Channels; Epilepsy; G

2008
Cl(-) conduction of GABAA receptor complex of synaptic membranes in the cortex of rats at the middle stage of chronic cerebral epileptization (pharmacological kindling).
    Bulletin of experimental biology and medicine, 2007, Volume: 144, Issue:5

    Topics: Animals; Cerebral Cortex; Chlorides; Chronic Disease; Dose-Response Relationship, Drug; Epilepsy; GA

2007
Canine epilepsy caused by flour bleached with nitrogen trichloride (agene); experimental method.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1947, Volume: 66, Issue:2

    Topics: Animals; Chlorides; Dog Diseases; Dogs; Epilepsy; Flour; Nitrogen Compounds

1947
Canine epilepsy caused by flour bleached with nitrogen trichloride (agene); role of amino acids.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1947, Volume: 66, Issue:2

    Topics: Amino Acids; Animals; Chlorides; Dog Diseases; Dogs; Epilepsy; Flour; Nitrogen Compounds

1947
Chronic impact of topiramate on acid-base balance and potassium in childhood.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2010, Volume: 14, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Anticonvulsants; Bicarbonates; Child; Child, Preschool;

2010
The K+-Cl cotransporter KCC2 promotes GABAergic excitation in the mature rat hippocampus.
    The Journal of physiology, 2010, May-01, Volume: 588, Issue:Pt 9

    Topics: Animals; Anticonvulsants; Barium; Bicarbonates; CA1 Region, Hippocampal; Carbonic Anhydrase Inhibito

2010
The difference in seizure incidences between young and adult rats related to lipid peroxidation after intracortical injection of ferric chloride.
    Singapore medical journal, 2010, Volume: 51, Issue:2

    Topics: Age Factors; Animals; Brain; Brain Hemorrhage, Traumatic; Chlorides; Disease Models, Animal; Epileps

2010
KCC2 was downregulated in small neurons localized in epileptogenic human focal cortical dysplasia.
    Epilepsy research, 2011, Volume: 93, Issue:2-3

    Topics: Adult; Child; Chlorides; Down-Regulation; Drug Resistance; Epilepsy; Female; gamma-Aminobutyric Acid

2011
Differences in automated analyzers for assessing the use of imprecise serum chloride concentrations as indirect predictors of serum bromide concentrations.
    Epilepsy research, 2011, Volume: 96, Issue:1-2

    Topics: Adolescent; Adult; Bromides; Child; Child, Preschool; Chlorides; Electronic Data Processing; Epileps

2011
Amygdala kindling induces upregulation of mRNA for NKCC1, a Na(+), K(+)-2Cl(-) cotransporter, in the rat piriform cortex.
    Neuroscience research, 2002, Volume: 44, Issue:2

    Topics: Amygdala; Animals; Chlorides; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Gene Expres

2002
The role of chloride-dependent inhibition and the activity of fast-spiking neurons during cortical spike-wave electrographic seizures.
    Neuroscience, 2002, Volume: 114, Issue:4

    Topics: Action Potentials; Animals; Cats; Cerebral Cortex; Chlorides; Electric Impedance; Epilepsy; gamma-Am

2002
Neocortical very fast oscillations (ripples, 80-200 Hz) during seizures: intracellular correlates.
    Journal of neurophysiology, 2003, Volume: 89, Issue:2

    Topics: Animals; Cats; Chlorides; Electric Stimulation; Electrodes; Electroencephalography; Epilepsy; Membra

2003
Ih blockers have a potential of antiepileptic effects.
    Epilepsia, 2003, Volume: 44, Issue:1

    Topics: Animals; Anticonvulsants; Calcium Channels; Cesium; Chlorides; Dose-Response Relationship, Drug; Ele

2003
Effect of zonisamide on molecular regulation of glutamate and GABA transporter proteins during epileptogenesis in rats with hippocampal seizures.
    Brain research. Molecular brain research, 2003, Aug-19, Volume: 116, Issue:1-2

    Topics: Amino Acid Transport System X-AG; Amygdala; Animals; Anticonvulsants; Blotting, Western; Carrier Pro

2003
[Results of the treatment of epilepsy using E. I. Karmanova's method].
    Suvremenna meditsina, 1958, Volume: 9, Issue:7

    Topics: Adonis; Bromides; Chlorides; Epilepsy

1958
[PATHO-BIOCHEMICAL STUDIES ON EPILEPSY. I. DAILY VARIATION OF BLOOD CONTENTS WITH SPECIAL REFERENCE TO SERUM ELECTROLYTES].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1964, Volume: 66

    Topics: Adolescent; Blood Chemical Analysis; Child; Chlorides; Epilepsy; Periodicity; Potassium; Sodium

1964
[CLINICAL EXPERIENCE IN WEANING WITH DIURETICS].
    Medizinische Klinik, 1964, Jun-26, Volume: 59

    Topics: Biological Transport; Breast Diseases; Breast Feeding; Chlorides; Diabetes Mellitus; Diuretics; Epil

1964
Antioxidant ability and lipid peroxidation in the hippocampus with epileptogenesis induced by Fe3+ injection into the amygdaloid body of rats.
    Neurochemical research, 2003, Volume: 28, Issue:12

    Topics: Amygdala; Animals; Antioxidants; Chlorides; Epilepsy; Ferric Compounds; Hippocampus; Lipid Peroxidat

2003
Effect of single injection of pentylenetetrazole in a subconvulsive dose on Cl- conductance of the GABAA-receptor complex.
    Bulletin of experimental biology and medicine, 2004, Volume: 137, Issue:1

    Topics: Animals; Cerebral Cortex; Chloride Channels; Chlorides; Convulsants; Electric Conductivity; Epilepsy

2004
Topiramate modulates pH of hippocampal CA3 neurons by combined effects on carbonic anhydrase and Cl-/HCO3- exchange.
    British journal of pharmacology, 2004, Volume: 142, Issue:5

    Topics: Action Potentials; Ammonium Chloride; Animals; Anticonvulsants; Bicarbonates; Carbon Dioxide; Carbon

2004
Canine epilepsy caused by flour bleached with nitrogen trichloride; histopathology.
    Journal of neuropathology and experimental neurology, 1949, Volume: 8, Issue:4

    Topics: Animals; Chlorides; Dogs; Epilepsy; Flour; Nitrogen Compounds

1949
Role of muscarinic and nicotinic cholinergic receptors in an experimental model of epilepsy-induced analgesia.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:2

    Topics: Animals; Atropine; Chlorides; Convulsants; Epilepsy; GABA Antagonists; Male; Mecamylamine; Muscarini

2004
Impaired Cl- extrusion in layer V pyramidal neurons of chronically injured epileptogenic neocortex.
    Journal of neurophysiology, 2005, Volume: 93, Issue:4

    Topics: Animals; Bumetanide; Chlorides; Chronic Disease; Epilepsy; K Cl- Cotransporters; Membrane Potentials

2005
7beta-hydroxycholesterol reduces the extent of reactive gliosis caused by iron deposition in the hippocampus but does not attenuate the iron-induced seizures in rats.
    Neuroscience, 2006, Volume: 138, Issue:4

    Topics: Action Potentials; Animals; Anti-Inflammatory Agents; Astrocytes; Brain Injuries; Chlorides; Convuls

2006
Neocortical microenvironment in patients with intractable epilepsy: potassium and chloride concentrations.
    Epilepsia, 2006, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Brain Chemistry; Chlorides; Drug Resistance; Electric Stimulatio

2006
Assessment of the use of plasma and serum chloride concentrations as indirect predictors of serum bromide concentrations in dogs with idiopathic epilepsy.
    Veterinary clinical pathology, 2006, Volume: 35, Issue:4

    Topics: Animals; Bromides; Chlorides; Dog Diseases; Dogs; Epilepsy; Female; Male; Predictive Value of Tests;

2006
Altered distribution of KCC2 in cortical dysplasia in patients with intractable epilepsy.
    Epilepsia, 2007, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Aged, 80 and over; Cerebral Cortex; Child; Child, Preschool; Chlorides; Coloring

2007
Cation-chloride cotransporters and GABA-ergic innervation in the human epileptic hippocampus.
    Epilepsia, 2007, Volume: 48, Issue:4

    Topics: Adult; Aged; Animals; Blotting, Western; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Hippocampus;

2007
Cl- conduction of GABA(A) receptor complex on synaptic membranes in rat cortex at the early stage of chronic cerebral epileptization.
    Bulletin of experimental biology and medicine, 2006, Volume: 142, Issue:2

    Topics: Animals; Cerebral Cortex; Chlorides; Convulsants; Epilepsy; Male; Pentylenetetrazole; Rats; Rats, Wi

2006
Distinct types of ionic modulation of GABA actions in pyramidal cells and interneurons during electrical induction of hippocampal seizure-like network activity.
    The European journal of neuroscience, 2007, Volume: 25, Issue:9

    Topics: Action Potentials; Animals; Cell Membrane; Chloride Channels; Chlorides; Epilepsy; Epilepsy, Tempora

2007
Functional role for redox in the epileptogenesis: molecular regulation of glutamate in the hippocampus of FeCl3-induced limbic epilepsy model.
    Experimental brain research, 2007, Volume: 181, Issue:4

    Topics: Animals; Behavior, Animal; Chlorides; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Transp

2007
In vivo EPR estimation of bilateral hippocampal antioxidant ability of rats with epileptogenesis induced by amygdalar FeCl3 microinjection.
    Epilepsia, 2007, Volume: 48, Issue:10

    Topics: Amygdala; Animals; Antioxidants; Chlorides; Chronic Disease; Disease Models, Animal; Electrodes, Imp

2007
Role of carbon dioxide and of the hindbrain in agene-induced canine epilepsy.
    The American journal of physiology, 1948, Sep-01, Volume: 154, Issue:3

    Topics: Animals; Carbon Dioxide; Chlorides; Dogs; Epilepsy; Nitrogen Compounds; Rhombencephalon

1948
Canine epilepsy caused by flour bleached with nitrogen trichloride (agene) electroencephalographic analysis.
    Archives of neurology and psychiatry, 1948, Volume: 60, Issue:4

    Topics: Animals; Chlorides; Dogs; Electroencephalography; Epilepsy; Flour; Nitrogen Compounds

1948
Low- and high-frequency electric cortical stimulation suppress the ferric chloride-induced seizures in rats.
    Neuroscience letters, 2008, Jan-17, Volume: 430, Issue:3

    Topics: Action Potentials; Animals; Cerebral Cortex; Chlorides; Convulsants; Electric Stimulation Therapy; E

2008
Manganese enhanced MRI detects mossy fiber sprouting rather than neurodegeneration, gliosis or seizure-activity in the epileptic rat hippocampus.
    NeuroImage, 2008, May-01, Volume: 40, Issue:4

    Topics: Algorithms; Animals; Blood-Brain Barrier; Chlorides; Chronic Disease; Contrast Media; Data Interpret

2008
Inhibitory role of Acorus calamus in ferric chloride-induced epileptogenesis in rat.
    Human & experimental toxicology, 2007, Volume: 26, Issue:12

    Topics: Acorus; Animals; Behavior, Animal; Catalase; Chlorides; Disease Models, Animal; Electroencephalograp

2007
[Calcium, potassium and chloride: studies on experimental epilepsy].
    Wiener klinische Wochenschrift. Supplementum, 1980, Volume: 121

    Topics: Calcium; Chlorides; Epilepsy; Humans; Membrane Potentials; Neurotransmitter Agents; Potassium; Synap

1980
Ionic and acid-base regulation of neurons and glia during seizures.
    Annals of neurology, 1984, Volume: 16 Suppl

    Topics: Acid-Base Equilibrium; Adenosine Triphosphatases; Animals; Anion Transport Proteins; Bicarbonates; C

1984
Formation of superoxide radicals after FeCl3 injection into rat isocortex.
    Brain research, 1983, Oct-31, Volume: 277, Issue:2

    Topics: Animals; Cerebral Cortex; Chlorides; Electron Spin Resonance Spectroscopy; Epilepsy; Ferric Compound

1983
High affinity (3H) beta-alanine uptake by scar margins of ferric chloride-induced epileptogenic foci in rat isocortex.
    Journal of neuropathology and experimental neurology, 1984, Volume: 43, Issue:4

    Topics: Alanine; Animals; Astrocytes; beta-Alanine; Cerebral Cortex; Chlorides; Epilepsy; Ferric Compounds;

1984
Changes in the activity of gamma-amino butyric acid transaminase and succinic semialdehyde dehydrogenase in the cobalt and iron experimental epileptogenic foci in the rat brain.
    Biochemistry international, 1984, Volume: 9, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Chlorides; Cobalt; Electroencephalography; Epilepsy; F

1984
Deviation of somatosensory evoked potential and lateral dominance of spike activity in iron-induced epileptic cortex of the rat.
    Acta medica Okayama, 1983, Volume: 37, Issue:5

    Topics: Animals; Cerebral Cortex; Chlorides; Epilepsy; Evoked Potentials, Somatosensory; Ferric Compounds; F

1983
Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy.
    Journal of neurosurgery, 1984, Volume: 60, Issue:3

    Topics: Animals; Brain Injuries; Chlorides; Electroencephalography; Epilepsy; Ferric Compounds; Lipid Peroxi

1984
Afterpotentials of penicillin-induced epileptiform neuronal discharges in the motor cortex of the rat in vivo.
    Epilepsy research, 1994, Volume: 18, Issue:1

    Topics: Action Potentials; Animals; Calcium; Chlorides; Epilepsy; Evoked Potentials; Male; Microelectrodes;

1994
(+-)-1-Amino-1,3-cyclopentane-trans-dicarboxylic acid (trans-ACPD) induced inositol triphosphoric acid formation in the brain of iron-induced epileptic rats and epileptic El mice.
    Research communications in chemical pathology and pharmacology, 1994, Volume: 84, Issue:2

    Topics: Animals; Brain; Chlorides; Cycloleucine; Disease Models, Animal; Epilepsy; Ferric Compounds; Inosito

1994
Free radical scavenging action of baicalein.
    Archives of biochemistry and biophysics, 1993, Volume: 306, Issue:1

    Topics: Animals; Brain; Cerebral Cortex; Chlorides; Drugs, Chinese Herbal; Electron Spin Resonance Spectrosc

1993
GABA-responses of CA3 neurones at epileptogenic threshold concentrations of convulsants.
    Neuroreport, 1993, Volume: 4, Issue:6

    Topics: Action Potentials; Animals; Bicarbonates; Bicuculline; Caffeine; Chlorides; Convulsants; Epilepsy; g

1993
High dietary chloride content associated with loss of therapeutic serum bromide concentrations in an epileptic dog.
    Journal of the American Veterinary Medical Association, 1996, Jan-15, Volume: 208, Issue:2

    Topics: Animals; Anticonvulsants; Bromides; Chlorides; Diet; Dog Diseases; Dogs; Epilepsy; Female; Liver; Ph

1996
Reduction in nitric oxide synthase activity with development of an epileptogenic focus induced by ferric chloride in the rat brain.
    Epilepsy research, 1996, Volume: 25, Issue:2

    Topics: Animals; Brain; Chlorides; Disease Models, Animal; Epilepsy; Ferric Compounds; Male; Nitric Oxide Sy

1996
Hyponatremia induced by oxcarbazepine in children.
    Epilepsy research, 1998, Volume: 30, Issue:3

    Topics: Anticonvulsants; Carbamazepine; Child; Chlorides; Electroencephalography; Epilepsy; Female; Humans;

1998
Extracellular chloride and the maintenance of spontaneous epileptiform activity in rat hippocampal slices.
    Journal of neurophysiology, 1999, Volume: 81, Issue:1

    Topics: 4-Aminopyridine; Animals; Bicuculline; Chlorides; Diuretics; Epilepsy; Furosemide; GABA Antagonists;

1999
Release of zinc from the brain of El (epilepsy) mice during seizure induction.
    Brain research, 1999, May-15, Volume: 828, Issue:1-2

    Topics: Animals; Autoradiography; Brain; Chlorides; Epilepsy; Homeostasis; Male; Mice; Mice, Mutant Strains;

1999
Electroencephalographic study of iron-induced chronic focal cortical epilepsy in rat: propagation of cortical epileptic activity to substantia nigra and thalamus.
    Indian journal of experimental biology, 1999, Volume: 37, Issue:5

    Topics: Animals; Chlorides; Electroencephalography; Electrophysiology; Epilepsy; Ferric Compounds; Male; Rat

1999
Electroencephalographic study of the effect of neurotoxin DSP-4 in iron model of chronic focal epilepsy.
    Indian journal of experimental biology, 1999, Volume: 37, Issue:5

    Topics: Animals; Benzylamines; Cerebral Cortex; Chlorides; Electroencephalography; Epilepsy; Ferric Compound

1999
Sustained plateau activity precedes and can generate ictal-like discharges in low-Cl(-) medium in slices from rat piriform cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Dec-15, Volume: 19, Issue:24

    Topics: Animals; Cerebral Cortex; Chlorides; Culture Media; Electric Stimulation; Electrophysiology; Epileps

1999
Chloride-cotransport blockade desynchronizes neuronal discharge in the "epileptic" hippocampal slice.
    Journal of neurophysiology, 2000, Volume: 83, Issue:1

    Topics: 4-Aminopyridine; Animals; Axons; Bicuculline; Carrier Proteins; Chlorides; Electric Stimulation; Epi

2000
Sequential changes in glutamate transporter mRNA levels during Fe(3+)-induced epileptogenesis.
    Brain research. Molecular brain research, 2000, Jan-10, Volume: 75, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Carrier Proteins; Cere

2000
Sodium pump activity, not glial spatial buffering, clears potassium after epileptiform activity induced in the dentate gyrus.
    Journal of neurophysiology, 2000, Volume: 83, Issue:3

    Topics: Animals; Chlorides; Dentate Gyrus; Enzyme Inhibitors; Epilepsy; Evoked Potentials; Extracellular Spa

2000
Sequential changes in glutamate transporter protein levels during Fe(3+)-induced epileptogenesis.
    Epilepsy research, 2000, Volume: 39, Issue:3

    Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Blotting, Western; Bra

2000
Central hyperventilation related to administration of topiramate.
    Pediatric neurology, 2000, Volume: 22, Issue:4

    Topics: Adolescent; Anticonvulsants; Bicarbonates; Chlorides; Epilepsy; Female; Fructose; Humans; Hyperventi

2000
Bromide-induced pseudohyperchloridemia.
    Pediatric neurology, 2000, Volume: 22, Issue:4

    Topics: Bromides; Chlorides; Epilepsy; Humans; Metabolic Diseases

2000
Anticonvulsive and free radical scavenging activities of vanillyl alcohol in ferric chloride-induced epileptic seizures in Sprague-Dawley rats.
    Life sciences, 2000, Volume: 67, Issue:10

    Topics: Acridines; Animals; Anticonvulsants; Behavior, Animal; Benzyl Alcohols; Brain; Chlorides; Convulsant

2000
Zonisamide reduces the increase in 8-hydroxy-2'-deoxyguanosine levels formed during iron-induced epileptogenesis in the brains of rats.
    Epilepsia, 2000, Volume: 41, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticonvulsants; Brain Chemistry; Cerebral Cortex; Chlorides;

2000
A role for sodium and chloride in kainic acid-induced beading of inhibitory interneuron dendrites.
    Neuroscience, 2000, Volume: 101, Issue:2

    Topics: Animals; Calcium; Chloride Channels; Chlorides; Dendrites; Dose-Response Relationship, Drug; Epileps

2000
Sequential changes in AMPA and NMDA protein levels during Fe(3+)-induced epileptogenesis.
    Brain research. Molecular brain research, 2001, Aug-15, Volume: 92, Issue:1-2

    Topics: Amygdala; Animals; Calcium; Chlorides; Convulsants; Epilepsy; Ferric Compounds; Glutamic Acid; Hippo

2001
Penicillin decreases chloride conductance in crustacean muscle: a model for the epileptic neuron.
    Brain research, 1976, Apr-30, Volume: 107, Issue:1

    Topics: Animals; Brachyura; Cell Membrane; Chlorides; Disease Models, Animal; Dose-Response Relationship, Dr

1976
Clinical biochemistry of epilepsy. I. Nature of the disease and a review of the chemical findings in epilepsy.
    Clinical chemistry, 1979, Volume: 25, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Animals; Blood Glucose; Calcium; Child; Chlorides; Cholesterol;

1979
Clinical biochemistry of epilepsy. II. Observations on two types of epileptiform convulsions induced in rabbits with corticotropin.
    Clinical chemistry, 1979, Volume: 25, Issue:6

    Topics: Adrenocorticotropic Hormone; Animals; Blood Chemical Analysis; Blood Pressure; Calcitonin; Calcium;

1979
Epileptic-type convulsions and magnesium deficiency.
    Aviation, space, and environmental medicine, 1979, Volume: 50, Issue:7

    Topics: Acclimatization; Adult; Chlorides; Epilepsy; Hot Temperature; Humans; Magnesium; Magnesium Deficienc

1979
Monoamine metabolites, iron induced seizures, and the anticonvulsant effect of tannins.
    Neurochemical research, 1992, Volume: 17, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anticonvulsants; Biogenic Monoamines; Brain; Catechin; Chlo

1992
Antioxidant and free radical scavenging activities of Gastrodia elata Bl. and Uncaria rhynchophylla (Miq.) Jacks.
    Neuropharmacology, 1992, Volume: 31, Issue:12

    Topics: Animals; Antioxidants; Brain; Chlorides; Drugs, Chinese Herbal; Epilepsy; Ferric Compounds; Free Rad

1992
Free radical scavenging action of Bio-catalyzer alpha.rho No.11 (Bio-normalyzer) and its by-product.
    Free radical biology & medicine, 1991, Volume: 11, Issue:4

    Topics: Animals; Cerebral Cortex; Chlorides; Electron Spin Resonance Spectroscopy; Epilepsy; Fermentation; F

1991
4-aminopyridine and barium chloride attenuate the anti-epileptic effect of carbamazepine in hippocampal slices.
    Experientia, 1991, Mar-15, Volume: 47, Issue:3

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Barium; Barium Compounds; Carbamazepine; Chlorides; Depre

1991
Epileptiform activity induced by low chloride medium in the CA1 subfield of the hippocampal slice.
    Journal of neurophysiology, 1990, Volume: 64, Issue:6

    Topics: Animals; Anticonvulsants; Chlorides; Electric Stimulation; Electrodes; Epilepsy; Evoked Potentials;

1990
GABA-gated chloride ion influx in brains of epileptic El mice.
    Neurochemical research, 1990, Volume: 15, Issue:9

    Topics: Animals; Brain; Chlorides; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Ion Channel Ga

1990
Antioxidant action of guilingji in the brain of rats with FeCl3-induced epilepsy.
    Free radical biology & medicine, 1990, Volume: 9, Issue:5

    Topics: Animals; Anticonvulsants; Antioxidants; Brain; Chlorides; Drugs, Chinese Herbal; Epilepsy; Ferric Co

1990
Alterations of inhibitory processes in the dentate gyrus following kindling-induced epilepsy.
    Experimental brain research, 1985, Volume: 57, Issue:3

    Topics: Animals; Calcium-Binding Proteins; Chlorides; Electric Stimulation; Epilepsy; gamma-Aminobutyric Aci

1985
Intracellular recordings in pericruciate neurons during spike and wave discharges of feline generalized penicillin epilepsy.
    Brain research, 1987, Mar-03, Volume: 405, Issue:1

    Topics: Animals; Cats; Cerebral Cortex; Chlorides; Epilepsy; Evoked Potentials; Neural Inhibition; Penicilli

1987
GABAergic inhibition and the induction of spontaneous epileptiform activity by low chloride and high potassium in the hippocampal slice.
    Brain research, 1988, Mar-29, Volume: 445, Issue:1

    Topics: Animals; Chlorides; Epilepsy; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Membrane P

1988
Dynamic variations of the brain cell microenvironment in relation to neuronal hyperactivity.
    Annals of the New York Academy of Sciences, 1986, Volume: 481

    Topics: Animals; Bees; Brain; Calcium; Cations; Cats; Chlorides; Epilepsy; Extracellular Space; Membrane Pot

1986
The role of the corpus callosum in interhemispheric propagation of iron-induced epileptogenic activity in the rat.
    Acta medica Okayama, 1985, Volume: 39, Issue:5

    Topics: Animals; Chlorides; Corpus Callosum; Electroencephalography; Electrophysiology; Epilepsy; Ferric Com

1985
Low potassium levels in the cerebrospinal fluid of forty mentally subnormal epileptics.
    Journal of mental deficiency research, 1970, Volume: 14, Issue:3

    Topics: Adenosine Triphosphatases; Adolescent; Adult; Bicarbonates; Chlorides; Epilepsy; Glycolysis; Humans;

1970
Intracellular study of seizure-like afterdischarges elicited in thin hippocampal sections in vitro.
    Experimental neurology, 1972, Volume: 35, Issue:1

    Topics: Action Potentials; Animals; Chlorides; Electric Stimulation; Epilepsy; Guinea Pigs; Hippocampus; Str

1972
The uptake of 36C1 into astrocytes in tissue culture by a potassium-dependent, saturable process: implications for epilepsy and cortical edema.
    Transactions of the American Neurological Association, 1973, Volume: 98

    Topics: Animals; Brain; Brain Edema; Bromides; Buffers; Cell Line; Cells, Cultured; Chlorides; Clone Cells;

1973
Free amino acid levels in the cerebrospinal fluid of normal humans and their variation in cases of epilepsy and Spielmeyer-Vogt-Batten disease.
    Journal of neurochemistry, 1974, Volume: 23, Issue:3

    Topics: Amino Acids; Autoanalysis; Chlorides; Chromatography, Ion Exchange; Epilepsy; Glucose; Humans; Lipid

1974
Adenosine deaminase in cerebrospinal fluid.
    Enzymologia, 1972, Dec-31, Volume: 43, Issue:6

    Topics: Adenosine; Adolescent; Adult; Aged; Aminohydrolases; Brain; Brain Neoplasms; Central Nervous System

1972
[The value of cerebrospinal fluid tests in the differential diagnosis of epilepsy of traumatic and infectious origin].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:8

    Topics: Adolescent; Adult; Blood-Brain Barrier; Central Nervous System Diseases; Cerebrospinal Fluid Protein

1970
[On the distribution of arginine and arginine break-down products with monosubstituted quanidyl groups in cerebrospinal fluid].
    Deutsche Zeitschrift fur Nervenheilkunde, 1967, Volume: 190, Issue:2

    Topics: Adolescent; Adult; Arginine; Atrophy; Brain Diseases; Calcium; Cerebral Ventriculography; Child; Chi

1967
Cerebrospinal fluid electrolyte disturbances in neurological disorders: with special reference to inorganic phosphate.
    Neurology, 1970, Volume: 20, Issue:3

    Topics: Brain Neoplasms; Central Nervous System Diseases; Cerebrovascular Disorders; Chlorides; Electrolytes

1970
Water, electrolytes and epilepsy.
    Journal of the neurological sciences, 1970, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Body Weight; Bromine; Chlorides; Depression; Electroencephalography; Epilepsy; Fe

1970
Ammonium chloride as an adjuvant to diphenyl-hydantoin therapy, and bulk ions in the CSF and serum in forty mentally subnormal epileptics.
    Journal of mental deficiency research, 1970, Volume: 14, Issue:2

    Topics: Ammonium Chloride; Bicarbonates; Calcium; Carbon Dioxide; Chlorides; Epilepsy; Humans; Intellectual

1970
Effects of diphenylhydantoin, pH and total carbon dioxide in the cerebrospinal fluid during sodium bicarbonate and ammonium chloride intake in forty mentally sub-normal epileptics.
    Journal of mental deficiency research, 1970, Volume: 14, Issue:1

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Ammonium Chloride; Bicarbonates; Calcium; Carbon Dioxide;

1970
Ammonium chloride as an adjuvant to diphenylhydantoin therapy, and pH, base bicarbonate and sodium in the serum of forty mentally subnormal epileptics.
    Journal of mental deficiency research, 1970, Volume: 14, Issue:1

    Topics: Acid-Base Equilibrium; Ammonium Chloride; Bicarbonates; Chlorides; Epilepsy; Humans; Hydrogen-Ion Co

1970
Porphyria variegata presenting as postpartum hypertension and epilepsy.
    Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:8

    Topics: Adult; Chlorides; Diagnosis, Differential; Epilepsy; Female; Humans; Hypertension; Hyponatremia; Por

1971
Low specific gravity syndrome.
    Clinical chemistry, 1968, Volume: 14, Issue:5

    Topics: Adult; Anticonvulsants; Calcium; Chlorides; Chronic Disease; Creatinine; Epilepsy; Female; Humans; I

1968