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chlorine and Acute Liver Injury, Drug-Induced

chlorine has been researched along with Acute Liver Injury, Drug-Induced in 47 studies

chloride : A halide anion formed when chlorine picks up an electron to form an an anion.

Research Excerpts

ExcerptRelevanceReference
"Vinyl chloride (VC) is a prevalent environmental toxicant that is rapidly metabolized within the liver."1.51Rapamycin attenuates liver injury caused by vinyl chloride metabolite chloroethanol and lipopolysaccharide in mice. ( Arteel, GE; Beier, JI; Chen, L; Kaelin, BR; Krueger, AM; Lang, AL; Rakutt, MJ; Schnegelberger, RD, 2019)
" The results showed that the contents of serum TP and ALB and hepatic Fe and Zn decreased and the contents of serum TBI and DBI and hepatic Al and Cu increased in the chickens with AlCl3 This indicates that chronic administration of AlCl3 impairs the hepatic metabolism function and disorders the hepatic trace elements' distribution."1.43Effects of aluminum chloride on serum proteins, bilirubin, and hepatic trace elements in chickens. ( Li, G; Li, Y; Liu, L; Song, Y; Wang, B; Zhang, H; Zhu, Y, 2016)
"The present work provided ethnopharmacological relevance of pomegranate peel against the toxic effects of barium, suggesting its beneficial role as a potential antioxidant."1.43Barium chloride induces redox status unbalance, upregulates cytokine genes expression and confers hepatotoxicity in rats-alleviation by pomegranate peel. ( Boudawara, O; Boudawara, T; Elwej, A; Ghorbel, I; Grojja, Y; Jarraya, R; Zeghal, N, 2016)
"Pretreatment with acteoside prior to the administration of carbon tetrachloride significantly prevented the increased serum enzymatic activities of alanine and aspartate aminotransferase in a dose-dependent manner."1.32Protective effect of acteoside on carbon tetrachloride-induced hepatotoxicity. ( Choi, CY; Jeong, HG; Lee, DG; Lee, KJ; Shin, DW; Woo, ER; You, HJ, 2004)
" Positive control of various concentrations of PEE on liver function and the dose-response relationship of liver injury induced by various doses of econazole were firstly observed from biochemical assay of serum level of aspartate transaminase (SGOT) and serum alanine transaminase (SGPT) and histopathological microscopic examination."1.32Antioxidative natural product protect against econazole-induced liver injuries. ( Chen, CF; Lin, CC; Lin, CH; Lin, CK; Lin, SC; Lin, YH; Liu, CF, 2004)
"Saccharin aversion was evident at levels of T-2 toxin that did not induce obvious tissue pathology."1.28Effects of T-2 toxin on saccharin aversion and food consumption in adult rats. ( Clark, DE; Cockroft, RD; Rowe, LD; Wellman, PJ, 1989)
"Chlorpromazine-treated mice displayed variation in liver nuclei size and in cell structure definition."1.27Effect of alkali metals on chlorpromazine toxicity in the mouse. ( Messiha, FS; Sproat, HF, 1983)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199021 (44.68)18.7374
1990's3 (6.38)18.2507
2000's6 (12.77)29.6817
2010's14 (29.79)24.3611
2020's3 (6.38)2.80

Authors

AuthorsStudies
Mahmarzayeva, D1
Bayrak, BB1
Turkyilmaz, IB1
Sacan, O1
Yanardag, R1
Lang, AL1
Krueger, AM1
Schnegelberger, RD1
Kaelin, BR1
Rakutt, MJ1
Chen, L1
Arteel, GE2
Beier, JI1
Famurewa, AC1
Ekeleme-Egedigwe, CA1
David, EE1
Eleazu, CO1
Folawiyo, AM1
Obasi, NA1
Abid, F1
Saleem, M1
Zaidi, AA1
Mobashar, A1
Yasir, S1
Xie, F1
Zhang, X1
Xie, L1
Debbache-Benaida, N1
Atmani-Kilani, D1
Schini-Keirth, VB1
Djebbli, N1
Atmani, D1
Eidi, A1
Mortazavi, P1
Behzadi, K1
Rohani, AH1
Safi, S1
Sharma, AK1
Kumar, S1
Chashoo, G1
Saxena, AK1
Pandey, AK1
Fan, WT1
Zhao, XN1
Cheng, J1
Liu, YH1
Liu, JZ1
Wang, B1
Zhu, Y1
Zhang, H1
Liu, L1
Li, G1
Song, Y1
Li, Y1
Elwej, A1
Grojja, Y1
Ghorbel, I1
Boudawara, O1
Jarraya, R1
Boudawara, T1
Zeghal, N1
Roy, A1
Tiwari, SP1
Kumari, K1
Gendley, MK1
Gupta, R1
Cho, WS1
Cho, M1
Jeong, J2
Choi, M1
Cho, HY1
Han, BS1
Kim, SH1
Kim, HO1
Lim, YT1
Chung, BH1
Jihen, el H2
Imed, M1
Fatima, H2
Abdelhamid, K2
Türkez, H2
Yousef, MI1
Geyikoglu, F2
Sonia, S1
Mohamed Tahar, S1
Chagas, PM1
Bortolatto, CF1
Wilhelm, EA1
Nogueira, CW1
Lebda, MA1
El-Neweshy, MS1
El-Sayed, YS1
Bakir, TO1
Cicek, M1
Alemmari, A1
Miller, GG1
Bertolo, RF1
Dinesh, C1
Brunton, JA1
Arnold, CJ1
Zello, GA1
GRACA, JG1
DAVISON, FC1
FEAVEL, JB1
Lee, KJ2
Woo, ER1
Choi, CY1
Shin, DW1
Lee, DG1
You, HJ1
Jeong, HG2
Liu, CF1
Lin, CH1
Lin, CC1
Lin, YH1
Chen, CF1
Lin, CK1
Lin, SC1
Choi, JH1
Kim, HG1
Han, EH1
Hwang, YP1
Lee, YC1
Chung, YC1
Sproat, HF1
Messiha, FS1
James, JL1
Moody, DE1
Chan, CH1
Smuckler, EA1
McKinney, PE1
Brent, J1
Kulig, K1
Demircan, M1
Ergün, O1
Coker, C1
Yilmaz, F1
Avanoglu, S1
Ozok, G1
Yin, M1
Ikejima, K1
Seabra, V1
Bradford, BU1
Kono, H1
Rusyn, I1
Thurman, RG1
Ohhama, I1
Kumagai, K1
Tamura, K1
Ohno, T1
Kano, M1
Satomi, M1
Shimoyama, T1
Nagy, I1
Kádas, I1
Jobst, K1
Suarez, KA1
Bhonsle, P1
Wellman, PJ1
Rowe, LD1
Clark, DE1
Cockroft, RD1
Brennaman, B1
Soucy, D1
Howard, RJ1
Farbiszewski, R1
Worowski, K1
Rzeczycki, W1
Bjondahl, K1
Möttönen, M1
Nieminen, L1
Sen, S1
Smeby, RR1
Bumpus, FM1
Taketa, K1
Watanabe, A1
Chang, LW1
Reuhl, KR1
Dudley, AW1
Lapis, K1
Schaff, Z1
Kiplinger, GF1
Gruber, CM1
Pierce, EC1
Selye, H1
Szabo, S1
Tuchweber, B1
Lefebvre, F1
Szelényi, I1
Nemesánszky, E1
Nagy, Z1
Nam, LB1
Romics, I1
Rigó, J1
Shelley, WB1
Raque, CJ1
Saldeen, T1
Preisser, G1
Schollmeyer, W1
Weisberg, H1
Strobos, RJ1
Rosenthal, WS1
Appleton, HD1
Glass, GB1

Trials

1 trial available for chlorine and Acute Liver Injury, Drug-Induced

ArticleYear
A comparative study of the effects of chronic administration of propoxyphene salts to normal volunteers.
    Toxicology and applied pharmacology, 1971, Volume: 19, Issue:3

    Topics: Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Chemical and Drug Induced Liver Inj

1971

Other Studies

46 other studies available for chlorine and Acute Liver Injury, Drug-Induced

ArticleYear
Oxidative brain and cerebellum injury induced by d-galactosamine: Protective effect of S-methyl methionine sulfonium chloride.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:9

    Topics: Acetylcholinesterase; Animals; Antioxidants; Brain; Carbonic Anhydrases; Catalase; Cerebellum; Chemi

2022
Rapamycin attenuates liver injury caused by vinyl chloride metabolite chloroethanol and lipopolysaccharide in mice.
    Toxicology and applied pharmacology, 2019, 11-01, Volume: 382

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorides; Ethanol; Lipopolysaccharides; Male; Mice

2019
Zinc abrogates anticancer drug tamoxifen-induced hepatotoxicity by suppressing redox imbalance, NO/iNOS/NF-ĸB signaling, and caspase-3-dependent apoptosis in female rats.
    Toxicology mechanisms and methods, 2020, Volume: 30, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; Chlorides; Cytokines; Diet

2020
Acacia modesta attenuates MnCl2 induced hepatotoxicity, oxidative stress and hepatic inflammation in wistar rats.
    Pakistan journal of pharmaceutical sciences, 2021, Volume: 34, Issue:1(Suppleme

    Topics: Acacia; Animals; Chemical and Drug Induced Liver Injury; Chlorides; Glutathione Peroxidase; Inflamma

2021
Prognostic value of serum zinc levels in patients with acute HC/zinc chloride smoke inhalation.
    Medicine, 2017, Volume: 96, Issue:39

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Bombs; Chemical and Drug Induced Liver Inj

2017
Pharmacological potential of Populus nigra extract as antioxidant, anti-inflammatory, cardiovascular and hepatoprotective agent.
    Asian Pacific journal of tropical biomedicine, 2013, Volume: 3, Issue:9

    Topics: Aluminum Chloride; Aluminum Compounds; Analysis of Variance; Animals; Anti-Inflammatory Agents; Card

2013
Hepatoprotective effect of manganese chloride against CCl4-induced liver injury in rats.
    Biological trace element research, 2013, Volume: 155, Issue:2

    Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlorides; Cytoprotection; Do

2013
Cell cycle inhibitory activity of Piper longum against A549 cell line and its protective effect against metal-induced toxicity in rats.
    Indian journal of biochemistry & biophysics, 2014, Volume: 51, Issue:5

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpo

2014
Oxidative stress and hepatocellular injury induced by oral administration of Cr(3+) in chicken.
    Journal of biochemical and molecular toxicology, 2015, Volume: 29, Issue:6

    Topics: Administration, Oral; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chickens; Chlor

2015
Effects of aluminum chloride on serum proteins, bilirubin, and hepatic trace elements in chickens.
    Toxicology and industrial health, 2016, Volume: 32, Issue:9

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Bilirubin; Blood Proteins; Chemical and Drug Induced

2016
Barium chloride induces redox status unbalance, upregulates cytokine genes expression and confers hepatotoxicity in rats-alleviation by pomegranate peel.
    Environmental science and pollution research international, 2016, Volume: 23, Issue:8

    Topics: Animals; Antioxidants; Barium Compounds; Chemical and Drug Induced Liver Injury; Chlorides; Cytokine

2016
Subchronic toxicity study of urea molasses mineral block in kids.
    Veterinary research communications, 2009, Volume: 33, Issue:2

    Topics: Alanine Transaminase; Animal Feed; Animals; Aspartate Aminotransferases; Chemical and Drug Induced L

2009
Acute toxicity and pharmacokinetics of 13 nm-sized PEG-coated gold nanoparticles.
    Toxicology and applied pharmacology, 2009, Apr-01, Volume: 236, Issue:1

    Topics: Acute Disease; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Chlorides; Gold Compounds

2009
Protective effects of selenium (Se) and zinc (Zn) on cadmium (Cd) toxicity in the liver of the rat: effects on the oxidative stress.
    Ecotoxicology and environmental safety, 2009, Volume: 72, Issue:5

    Topics: Animals; Antioxidants; Biomarkers; Body Weight; Cadmium Chloride; Catalase; Chemical and Drug Induce

2009
Propolis prevents aluminium-induced genetic and hepatic damages in rat liver.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:10

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aluminum Chloride; Aluminum Compounds; Animals; Antimuta

2010
Interrelationships between cadmium, zinc and antioxidants in the liver of the rat exposed orally to relatively high doses of cadmium and zinc.
    Ecotoxicology and environmental safety, 2011, Volume: 74, Issue:7

    Topics: Animals; Antioxidants; Cadmium; Cadmium Chloride; Chemical and Drug Induced Liver Injury; Chlorides;

2011
High doses of 2,2'-dithienyl diselenide cause systemic toxicity in rats: an in vitro and in vivo study.
    Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:6

    Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Catalase; Chemical and Drug Induced Liver Injury; Chlor

2013
Neurohepatic toxicity of subacute manganese chloride exposure and potential chemoprotective effects of lycopene.
    Neurotoxicology, 2012, Volume: 33, Issue:1

    Topics: Acetylcholinesterase; Alkaline Phosphatase; Animals; Antioxidants; Body Weight; Brain; Carotenoids;

2012
The genotoxic, hepatotoxic, nephrotoxic, haematotoxic and histopathological effects in rats after aluminium chronic intoxication.
    Toxicology and industrial health, 2013, Volume: 29, Issue:9

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aluminum Chloride; Aluminum Compounds; Animals; Aspartat

2013
Reduced aluminum contamination decreases parenteral nutrition associated liver injury.
    Journal of pediatric surgery, 2012, Volume: 47, Issue:5

    Topics: Aluminum Chloride; Aluminum Compounds; Animals; Bile Acids and Salts; Bilirubin; Biomarkers; Chemica

2012
COMPARATIVE TOXICITY OF STABLE RARE EARTH COMPOUNDS. III. ACUTE TOXICITY OF INTRAVENOUS INJECTIONS OF CHLORIDES AND CHELATES IN DOGS.
    Archives of environmental health, 1964, Volume: 8

    Topics: Blood Coagulation; Blood Pressure; Blood Pressure Determination; Chelating Agents; Chemical and Drug

1964
Protective effect of acteoside on carbon tetrachloride-induced hepatotoxicity.
    Life sciences, 2004, Jan-09, Volume: 74, Issue:8

    Topics: Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Carbon Tetr

2004
Antioxidative natural product protect against econazole-induced liver injuries.
    Toxicology, 2004, Mar-01, Volume: 196, Issue:1-2

    Topics: Alanine Transaminase; Animals; Antifungal Agents; Antioxidants; Aspartate Aminotransferases; Biologi

2004
Protective effect of saponins derived from the roots of Platycodon grandiflorum against carbon tetrachloride induced hepatotoxicity in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:5

    Topics: Animals; Ascorbic Acid; Blotting, Western; Campanulaceae; Carbon Tetrachloride Poisoning; Caspase 3;

2008
Effect of alkali metals on chlorpromazine toxicity in the mouse.
    Brain research bulletin, 1983, Volume: 11, Issue:2

    Topics: Animals; Cesium; Chemical and Drug Induced Liver Injury; Chlorides; Chlorpromazine; Drug Synergism;

1983
The phospholipids of the hepatic endoplasmic reticulum. Structural change in liver injury.
    The Biochemical journal, 1982, Aug-15, Volume: 206, Issue:2

    Topics: Adenosine Diphosphate; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Inju

1982
Acute zinc chloride ingestion in a child: local and systemic effects.
    Annals of emergency medicine, 1994, Volume: 23, Issue:6

    Topics: Acidosis; Acute Disease; Ammonium Chloride; Amylases; Burns, Chemical; Chemical and Drug Induced Liv

1994
Aluminum in total parenteral nutrition solutions produces portal inflammation in rats.
    Journal of pediatric gastroenterology and nutrition, 1998, Volume: 26, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals

1998
Glycine accelerates recovery from alcohol-induced liver injury.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Central Nervous System Depressants; Chem

1998
Gastric mucosal barrier in the rats fed with protein deficient diet or treated with carbon tetrachloride.
    Gastroenterologia Japonica, 1978, Volume: 13, Issue:6

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorides; Gastric

1978
Lanthanum Trichloride induced blood coagulation defect and liver injury.
    Haematologia, 1976, Volume: 10, Issue:3-4

    Topics: Animals; Antithrombins; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Chlorid

1976
Proceedings: The role of cytochrome P-450 in carbon tetrachloride-induced hepatic injury.
    The Journal of the American Osteopathic Association, 1976, Volume: 75, Issue:5

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorides; Cobalt;

1976
Effects of T-2 toxin on saccharin aversion and food consumption in adult rats.
    Physiology & behavior, 1989, Volume: 45, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorides; Dose-Response Relationship, Drug; Feedin

1989
Effect of iron and liver injury on the pathogenesis of Vibrio vulnificus.
    The Journal of surgical research, 1987, Volume: 43, Issue:6

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorides; Deferoxa

1987
The comparison of arginine content in serum proteins in rats with Guerin tumour and in experimental induced intoxication with CCl 4 and HgCl 2 .
    Neoplasma, 1971, Volume: 18, Issue:3

    Topics: Alkaline Phosphatase; Alpha-Globulins; Animals; Arginine; Beta-Globulins; Blood Proteins; Carbon Tet

1971
Effect of phenobarbital on acute toxicity and liver damage induced by cerium chloride in male mice.
    Annales medicinae experimentalis et biologiae Fenniae, 1973, Volume: 51, Issue:2

    Topics: Animals; Cerium; Chemical and Drug Induced Liver Injury; Chlorides; Depression, Chemical; Liver; Mal

1973
Effect of mercuric chloride on plasma renin substrate level in rats.
    The American journal of physiology, 1972, Volume: 222, Issue:1

    Topics: Angiotensin II; Animals; Blood Volume; Chemical and Drug Induced Liver Injury; Chlorides; Dactinomyc

1972
Interconvertible microheterogeneity of glucose-6-phosphate dehydrogenase in rat liver.
    Biochimica et biophysica acta, 1971, Apr-14, Volume: 235, Issue:1

    Topics: Acrylates; Animals; Carbon Tetrachloride Poisoning; Cattle; Centrifugation, Density Gradient; Chemic

1971
Effects of methylmercury chloride on Rana pipiens tadpoles.
    Environmental research, 1974, Volume: 8, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorides; Edema; Environmental Exposure; Hemosider

1974
Ultrastructural studies on D-galactosamine-HCl-induced liver injury in mice.
    Morphologiai es igazsagugyi orvosi szemle, 1973, Volume: 13, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorides; Female; Galactosamine; Liver; Mice

1973
Acute miliary necrosis resembling peliosis hepatitis produced by the combination of glucocorticoid and gadolinium chloride.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorides; Disease Models, Animal; Female; Gadolini

1972
[Experimental liver lesions and its influencing by anorganic and organic magnesium salts].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:6

    Topics: Animals; Asparagine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorid

1971
Experimental zirconium granulomas and chondromas in CBA mice.
    The Journal of investigative dermatology, 1971, Volume: 57, Issue:6

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorides; Chondroma; Ear Diseases; Ear Neoplasms;

1971
On the protective action of zinc against experimental liver damage due to choline free diet or carbon tetrachloride.
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1969, Volume: 150, Issue:3

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorides; Choline

1969
[Acute fatal gold chloride poisoning].
    Archiv fur Toxikologie, 1965, Jun-30, Volume: 20, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Chlorides; Cold Temperature; Female; Humans; Suicide

1965
The comparative effect of chlorothiazide and meralluride on the development of hepatic encephalopathy in cirrhotic patients.
    Gastroenterologia, 1966, Volume: 105, Issue:6

    Topics: Ammonia; Bicarbonates; Blood Urea Nitrogen; Body Weight; Brain Diseases; Chemical and Drug Induced L

1966