chlorine has been researched along with Acute Kidney Injury in 168 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although ataluren did not improve lung function in the overall population of nonsense-mutation cystic fibrosis patients who received this treatment, it might be beneficial for patients not taking chronic inhaled tobramycin." | 5.19 | Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial. ( Accurso, FJ; Ajayi, T; Barth, J; Branstrom, A; Bronsveld, I; De Boeck, K; Elborn, JS; Elfring, GL; Fajac, I; Kerem, E; Knoop, C; Konstan, MW; Malfroot, A; McColley, SA; Melotti, P; Peltz, SW; Quattrucci, S; Rietschel, E; Rosenbluth, DB; Rowe, SM; Sermet-Gaudelus, I; Spiegel, RJ; Walker, PA; Welch, EM; Wilschanski, M; Zeitlin, PL, 2014) |
| "Urine alkalinisation with sodium bicarbonate decreases renal oxidative stress and might attenuate sepsisassociated acute kidney injury (s-AKI)." | 5.17 | Safety evaluation of a trial of lipocalin-directed sodium bicarbonate infusion for renal protection in at-risk critically ill patients. ( Bellomo, R; Eastwood, GM; Garcia, M; Harley, N; Moore, E; Peck, L; Reade, M; Schneider, AG; Young, H, 2013) |
| " Laboratory tests confirmed features of acute kidney injury and high mercury levels in the blood (1051 μg/l) and urine (22 960 μg/l) - DMPS therapy and CRRT combined with CytoSorb were instituted." | 4.31 | Acute mercuric chloride poisoning at a potentially lethal dose ended with survival: symptoms, concentration in cerebrospinal fluid, treatment. ( Janasik, B; Krakowiak, A; Machała, W; Sadowski, Ł; Szwabe, K, 2023) |
| " Methemoglobinemia was found and intravenous methylene blue was given repeatedly." | 3.68 | Acute sodium chlorite poisoning associated with renal failure. ( Lim, PS; Lin, JL, 1993) |
| "New-onset acute kidney injury was observed in 10 patients (6." | 3.30 | Effect of Saline vs Gluconate/Acetate-Buffered Solution vs Lactate-Buffered Solution on Serum Chloride Among Children in the Pediatric Intensive Care Unit: The SPLYT-P Randomized Clinical Trial. ( Gibbons, KS; Kennedy, M; Le Marsney, R; Mattke, A; Raman, S; Schibler, A; Schlapbach, LJ; Trnka, P, 2023) |
| "To study dehydration related to the August 2003 heat wave in France in a cohort of adults with cystic fibrosis." | 2.43 | [Severe dehydration and August 2003 heat wave in a cohort of adults with cystic fibrosis]. ( Burgel, PR; Desmazes-Dufeu, N; Dusser, D; Hubert, D; Kanaan, R; Vélea, V, 2005) |
| "AKI patients with severe critical illness were extracted from the MIMIC-IV." | 1.91 | Lower serum chloride concentrations are associated with an increased risk of death in ICU patients with acute kidney injury: an analysis of the MIMIC-IV database. ( An, S; Chen, Y; Li, R; Liang, Q; Zhou, S, 2023) |
| " Pharmacokinetic analysis revealed that elevated plasma AM in RD-Ag rats may be caused by a reduced volume of distribution." | 1.72 | Plasma Clearance of Intravenously Infused Adrenomedullin in Rats with Acute Renal Failure. ( Hosoda, H; Nakamura, T; Yoshihara, F, 2022) |
| "The death-adjusted risk of ESRD was additionally evaluated." | 1.62 | Hyperchloremia is associated with poor renal outcome after coronary artery bypass grafting. ( Choi, JS; Han, SS; Joo, KW; Kim, DK; Kim, YS; Na, KY; Oh, KH; Yun, D, 2021) |
| "Patients with septic shock, defined according to Sepsis-2 definition, were eligible." | 1.62 | Does Chloride Intake at the Early Phase of Septic Shock Resuscitation Impact on Renal Outcome? ( Aubron, C; Balzer, T; Chapalain, X; Darreau, C; Delbove, A; Egreteau, PY; Huet, O; Jacquier, S; Lerolle, N; Martino, F; Saint-Martin, M, 2021) |
| "Hyperchloremic acidosis is associated with postoperative AKI, and this may be attenuated by reducing the intraoperative chloride load." | 1.46 | Hyperchloremic acidosis is associated with acute kidney injury after abdominal surgery. ( Kikura, M; Toyonaga, Y, 2017) |
| "Taurine plays an important role as an antioxidant and is consequently expected to protect tissues from damage caused by reactive oxygen metabolites." | 1.40 | The influence of taurine pretreatment on aluminum chloride induced nephrotoxicity in Swiss albino mice. ( Abdel-Moneim, AM; Al Kahtani, MA; El-Sayed, WM, 2014) |
| "When butein was administered in rats with cisplatin-induced ARF for 4 d, solute-free water reabsorption was improved by 91% compared with that of cisplatin-induced ARF rats, but creatinine clearance was not restored." | 1.32 | Butein ameliorates renal concentrating ability in cisplatin-induced acute renal failure in rats. ( Kang, DG; Kim, YC; Lee, AS; Lee, HS; Moon, MK; Mun, YJ; Sohn, EJ; Woo, WH, 2004) |
| "Cadmium chloride was continuously infused at the rate of 3." | 1.29 | [The effects of acute administration of cadmium chloride on renal hemodynamics in rats]. ( Eto, S; Hashimoto, O; Ikeda, M; Ito, Y; Kaizu, K; Komine, N; Uriu, K, 1993) |
| "Metabolic acidosis was demonstrated at Days 6, 13, and 28." | 1.27 | Liver, kidney, and central nervous system toxicity of aluminum given intraperitoneally to rats: a multiple-dose subchronic study using aluminum nitrilotriacetate. ( Ebina, Y; Hamazaki, S; Midorikawa, O; Okada, S, 1984) |
| "Thus, in contrast to human acute renal failure, marked renal cortical ischemia is not an essential feature of these different forms of murine acute renal failure." | 1.26 | Normal renocortical blood flow in experimental acute renal failure. ( Carvalho, JS; Churchill, S; Gottlieb, MN; Oken, DE; Zarlengo, MD, 1977) |
| "The use of potent diuretics in acute renal failure remains controversial." | 1.25 | Effects of furosemide on low-dose mercuric chloride acute renal failure in the rat. ( Freeman, RB; Jaenike, JR; Pabico, RC; Ufferman, RC, 1975) |
| "It was also raised in primary hemochromatosis." | 1.25 | Cobalt excretion test for the assessment of body iron stores. ( Corbett, WE; Olatunbosun, D; Sorbie, J; Valberg, LS, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 84 (50.00) | 18.7374 |
| 1990's | 5 (2.98) | 18.2507 |
| 2000's | 5 (2.98) | 29.6817 |
| 2010's | 40 (23.81) | 24.3611 |
| 2020's | 34 (20.24) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, JS | 1 |
| Yun, D | 1 |
| Kim, DK | 1 |
| Oh, KH | 1 |
| Joo, KW | 1 |
| Kim, YS | 1 |
| Na, KY | 1 |
| Han, SS | 1 |
| Thongprayoon, C | 4 |
| Vaitla, P | 1 |
| Nissaisorakarn, V | 2 |
| Mao, MA | 3 |
| Genovez, JLZ | 1 |
| Kattah, AG | 2 |
| Pattharanitima, P | 2 |
| Vallabhajosyula, S | 2 |
| Keddis, MT | 2 |
| Qureshi, F | 2 |
| Dillon, JJ | 2 |
| Garovic, VD | 2 |
| Kashani, KB | 2 |
| Cheungpasitporn, W | 3 |
| Ahmed, HM | 1 |
| Elnaby, HRH | 1 |
| El Kareem, RMA | 1 |
| Hodeib, M | 1 |
| Radhakrishnan, Y | 1 |
| Petnak, T | 1 |
| Zabala Genovez, J | 1 |
| Chewcharat, A | 1 |
| Hegab, AM | 1 |
| Khalil, FF | 1 |
| Abosedera, MM | 1 |
| Núñez-Martínez, FJ | 1 |
| Luna-Montalbán, R | 1 |
| Orozco-Juárez, K | 1 |
| Chávez-Lárraga, AJ | 1 |
| Velasco-Santos, JI | 1 |
| Verazaluce-Rodríguez, BE | 1 |
| Qian, J | 1 |
| Liu, L | 1 |
| Chu, F | 1 |
| Shen, Y | 2 |
| Bai, X | 1 |
| Lu, Z | 1 |
| Wang, Y | 3 |
| Tunbridge, M | 1 |
| Chandler, S | 1 |
| Isbel, N | 1 |
| Jegatheesan, D | 1 |
| McNeill, IR | 1 |
| Isoardi, K | 1 |
| Viecelli, AK | 1 |
| Zhu, X | 1 |
| Xue, J | 1 |
| Liu, Z | 2 |
| Dai, W | 1 |
| Xiang, J | 1 |
| Xu, H | 1 |
| Zhou, Q | 2 |
| Chen, W | 1 |
| Hosoda, H | 1 |
| Nakamura, T | 2 |
| Yoshihara, F | 1 |
| Li, R | 1 |
| Chen, Y | 1 |
| Liang, Q | 1 |
| Zhou, S | 1 |
| An, S | 1 |
| Ginter, D | 3 |
| Gilfoyle, E | 3 |
| Wade, A | 3 |
| Lethebe, BC | 3 |
| Gilad, E | 3 |
| Zhou, D | 3 |
| Jiang, J | 3 |
| Zhang, J | 3 |
| Cao, F | 3 |
| Peng, Z | 3 |
| Raman, S | 1 |
| Gibbons, KS | 1 |
| Mattke, A | 1 |
| Schibler, A | 1 |
| Trnka, P | 1 |
| Kennedy, M | 1 |
| Le Marsney, R | 1 |
| Schlapbach, LJ | 1 |
| Almuqamam, M | 1 |
| Novi, B | 1 |
| Rossini, CJ | 1 |
| Mammen, A | 1 |
| DeSanti, RL | 1 |
| Huet, O | 2 |
| Chapalain, X | 2 |
| Vermeersch, V | 1 |
| Moyer, JD | 1 |
| Lasocki, S | 1 |
| Cohen, B | 1 |
| Dahyot-Fizelier, C | 1 |
| Chalard, K | 1 |
| Seguin, P | 1 |
| Hourmant, Y | 1 |
| Asehnoune, K | 1 |
| Roquilly, A | 1 |
| Hellman, T | 1 |
| Uusalo, P | 1 |
| Järvisalo, MJ | 1 |
| Luglio, M | 1 |
| de Carvalho, WB | 1 |
| Tannuri, U | 1 |
| Tannuri, ACA | 1 |
| Matsura, RH | 1 |
| Morais França, G | 1 |
| Delgado, AF | 1 |
| Dhanani, LY | 1 |
| Totton, RR | 1 |
| Jara-Quijada, E | 1 |
| Pérez-Won, M | 1 |
| Tabilo-Munizaga, G | 1 |
| Lemus-Mondaca, R | 1 |
| González-Cavieres, L | 1 |
| Palma-Acevedo, A | 1 |
| Herrera-Lavados, C | 1 |
| Milovanovic, S | 1 |
| Grzegorczyk, A | 1 |
| Świątek, Ł | 1 |
| Grzęda, A | 1 |
| Dębczak, A | 1 |
| Tyskiewicz, K | 1 |
| Konkol, M | 1 |
| Li, Y | 2 |
| Chang, P | 1 |
| Sankaran, S | 1 |
| Jang, H | 1 |
| Nie, Y | 1 |
| Zeng, A | 1 |
| Hussain, S | 1 |
| Wu, JY | 1 |
| Chen, X | 2 |
| Shi, L | 2 |
| Senapati, A | 1 |
| Chetri, BK | 1 |
| Mitra, S | 1 |
| Shelke, RG | 1 |
| Rangan, L | 1 |
| Chauhan, AS | 1 |
| Tiwari, M | 1 |
| Indoliya, Y | 1 |
| Mishra, SK | 1 |
| Lavania, UC | 1 |
| Chauhan, PS | 1 |
| Chakrabarty, D | 1 |
| Tripathi, RD | 1 |
| Akaputra, R | 1 |
| Hatta, M | 1 |
| Massi, MN | 1 |
| Djaharuddin, I | 1 |
| Bukhari, A | 1 |
| Aminuddin, A | 1 |
| Santoso, A | 1 |
| Natzir, R | 1 |
| Bahar, B | 1 |
| Fachri, M | 1 |
| Farsida, F | 1 |
| Fathimah, A | 1 |
| Ubaidah, FM | 1 |
| Sridiana, E | 1 |
| Dwiyanti, R | 1 |
| Syukri, A | 1 |
| Junita, AR | 1 |
| Febrianti, A | 1 |
| Primaguna, MR | 1 |
| Azhar, A | 1 |
| Rajaure, YS | 1 |
| Thapa, B | 1 |
| Budhathoki, L | 1 |
| Rana, SR | 1 |
| Khadka, M | 1 |
| Batchu, UR | 1 |
| Surapaneni, JR | 1 |
| Cheemalamarri, C | 1 |
| Mandava, K | 1 |
| Puvvada, N | 1 |
| Shetty, PR | 1 |
| Mv, S | 1 |
| Ranjbarian, P | 1 |
| Goudarzi, F | 1 |
| Akya, A | 1 |
| Heidarinia, H | 1 |
| Farasat, A | 1 |
| Rostamian, M | 1 |
| Suri, K | 1 |
| Rajput, N | 1 |
| Sharma, P | 1 |
| Omble, AD | 1 |
| Kulkarni, K | 1 |
| Gahlay, GK | 1 |
| Fernandez Garcia, E | 1 |
| Paudel, U | 1 |
| Noji, MC | 1 |
| Bowman, CE | 1 |
| Rustgi, AK | 1 |
| Pitarresi, JR | 1 |
| Wellen, KE | 1 |
| Arany, Z | 1 |
| Weissenrieder, JS | 1 |
| Foskett, JK | 1 |
| Lee, MS | 1 |
| Han, HJ | 1 |
| Choi, TI | 1 |
| Lee, KH | 1 |
| Baasankhuu, A | 1 |
| Kim, HT | 1 |
| Kim, CH | 1 |
| Redd, PS | 1 |
| Payero, L | 1 |
| Gilbert, DM | 1 |
| Page, CA | 1 |
| King, R | 1 |
| McAssey, EV | 1 |
| Bodie, D | 1 |
| Diaz, S | 1 |
| Hancock, CN | 1 |
| Lee, HS | 2 |
| Jung, S | 1 |
| Lee, SW | 1 |
| Kim, YT | 1 |
| Lee, J | 1 |
| Ren, T | 1 |
| Yu, Z | 1 |
| Yu, H | 1 |
| Deng, K | 1 |
| Wang, Z | 1 |
| Li, X | 3 |
| Wang, H | 2 |
| Wang, L | 2 |
| Xu, Y | 1 |
| Lascano, J | 1 |
| Riley, L | 1 |
| Khodayari, N | 1 |
| Brantly, M | 1 |
| Gupta, R | 1 |
| Pradhan, J | 1 |
| Haldar, A | 1 |
| Murapaka, C | 1 |
| Chandra Mondal, P | 1 |
| Gao, R | 1 |
| Dai, TY | 1 |
| Meng, Z | 1 |
| Sun, XF | 1 |
| Liu, DX | 1 |
| Shi, MM | 1 |
| Li, HR | 1 |
| Kang, X | 1 |
| Bi, B | 1 |
| Zhang, YT | 1 |
| Xu, TW | 1 |
| Yan, JM | 1 |
| Jiang, Q | 1 |
| Helmchen, G | 1 |
| Guo, H | 1 |
| Xiang, W | 1 |
| Fang, Y | 1 |
| Li, J | 5 |
| Lin, Y | 1 |
| An, X | 1 |
| Jiang, D | 1 |
| Cao, Q | 1 |
| Xu, F | 1 |
| Shiigi, H | 1 |
| Wang, W | 1 |
| Chen, Z | 1 |
| Akosman, I | 1 |
| Kumar, N | 1 |
| Mortenson, R | 1 |
| Lans, A | 1 |
| De La Garza Ramos, R | 1 |
| Eleswarapu, A | 1 |
| Yassari, R | 1 |
| Fourman, MS | 1 |
| Jana, S | 1 |
| Evans, EGB | 1 |
| Jang, HS | 1 |
| Zhang, S | 2 |
| Zhang, H | 2 |
| Rajca, A | 1 |
| Gordon, SE | 1 |
| Zagotta, WN | 1 |
| Stoll, S | 1 |
| Mehl, RA | 1 |
| Miller, S | 1 |
| Lee, DA | 1 |
| Muhimpundu, S | 1 |
| Maxwell, CA | 1 |
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| Dong, Q | 1 |
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| Rothwell, KA | 1 |
| Fantappiè, G | 1 |
| ThomasArrigo, LK | 1 |
| Kretzschmar, R | 1 |
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| Prowle, JR | 1 |
| Komaru, Y | 1 |
| Doi, K | 1 |
| Matsuura, R | 1 |
| Yoshida, T | 1 |
| Miyamoto, Y | 1 |
| Yoshimoto, K | 1 |
| Nangaku, M | 1 |
| Barhight, MF | 2 |
| Brinton, JT | 1 |
| Soranno, DE | 2 |
| Faubel, S | 2 |
| Mourani, PM | 2 |
| Gist, KM | 2 |
| Sigmon, J | 1 |
| May, C | 1 |
| Gueret, G | 1 |
| Le Maguet, P | 1 |
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| Fabre, R | 1 |
| Kee, YK | 1 |
| Jeon, HJ | 1 |
| Oh, J | 1 |
| Shin, DH | 1 |
| Huang, L | 1 |
| Hu, Y | 1 |
| Jia, L | 1 |
| Pang, M | 1 |
| Zhao, Z | 1 |
| Li, L | 1 |
| Shen, R | 1 |
| Jiao, H | 1 |
| Ge, J | 1 |
| Song, X | 1 |
| Guo, X | 1 |
| Yu, B | 1 |
| Zhang, N | 1 |
| Balzer, T | 1 |
| Delbove, A | 1 |
| Martino, F | 1 |
| Jacquier, S | 1 |
| Egreteau, PY | 1 |
| Darreau, C | 1 |
| Saint-Martin, M | 1 |
| Lerolle, N | 1 |
| Aubron, C | 1 |
| Østergaard, AM | 1 |
| Jørgensen, AN | 1 |
| Bøvling, S | 1 |
| Ekeløf, NP | 1 |
| Mose, FH | 2 |
| Bech, JN | 2 |
| Tehranian, S | 1 |
| Shawwa, K | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of 0,9% NaCl on the Kidney Function, Vasoactive Hormones, Biomarkers and Glycosaminglycanes in Plasma in Patients Operated on for Primary Hiparthrosis[NCT02528448] | Phase 4 | 40 participants (Anticipated) | Interventional | 2015-03-31 | Recruiting | ||
| Pirfenidone Effect on the Recovery of Renal Function in Patients With Septic Acute Kidney Injury[NCT02530359] | Phase 4 | 90 participants (Anticipated) | Interventional | 2015-10-31 | Not yet recruiting | ||
| A Phase 3 Efficacy and Safety Study of PTC124 as an Oral Treatment for Nonsense-Mutation-Mediated Cystic Fibrosis[NCT00803205] | Phase 3 | 238 participants (Actual) | Interventional | 2009-09-08 | Completed | ||
| Renal Effects of Fluid Resuscitation With Plasmalyte Viaflo Versus Saline in Trauma Patients (the ASTRAU Study)[NCT03630224] | Phase 3 | 622 participants (Anticipated) | Interventional | 2019-06-24 | Recruiting | ||
| Change in Serum Chloride Level After Loading Dose of Sterofundin Solution Compared With Normal Saline Solution[NCT02950974] | 20 participants (Actual) | Interventional | 2014-11-30 | Completed | |||
| Saline Against Lactated Ringers or Plasmalyte in the Emergency Department (SaLt-ED)[NCT02614040] | 14,000 participants (Actual) | Interventional | 2016-01-01 | Completed | |||
| Isotonic Solutions and Major Adverse Renal Events Trial in Non-Medical Intensive Care Units[NCT02547779] | 10,421 participants (Actual) | Interventional | 2015-10-01 | Completed | |||
| Isotonic Solution Administration Logistical Testing: Pilot Study for the Isotonic Solutions and Major Adverse Renal Events Trial[NCT02345486] | 974 participants (Actual) | Interventional | 2015-02-28 | Completed | |||
| Acetated Ringer's Solution Versus Saline in Patients With Septic Shock[NCT04507672] | 2,000 participants (Anticipated) | Interventional | 2020-09-01 | Not yet recruiting | |||
| A Prospective, Before and After Study of the Impact of Lower Chloride Intravenous Fluid Management on Patients' Acid-base Status, Renal Profile,Length of Stay and Mortality.[NCT00885404] | Phase 4 | 7,000 participants (Anticipated) | Interventional | 2009-02-28 | Active, not recruiting | ||
| Isotonic Solutions and Major Adverse Renal Events Trial in the Medical Intensive Care Unit[NCT02444988] | 5,381 participants (Actual) | Interventional | 2015-06-01 | Completed | |||
| Effect of Normal Saline Versus Balance Salt Solution Resuscitation on Kidney Function; A Randomized Open Label Controlled Study[NCT02520804] | 107 participants (Anticipated) | Interventional | 2014-11-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Spirometry was used to assess pulmonary function by measuring the percentage of predicted function, which was determined on the basis of the height value obtained at the same study visit, for FVC (the amount of air that can be exhaled after taking a deep breath). Spirometry was assessed by using current guidelines of the ATS and ERS. Baseline was the average of percent-predicted FVC at screening and randomization. (NCT00803205)
Timeframe: Baseline (Week 1)
| Intervention | percentage of predicted FVC (Mean) |
|---|---|
| Ataluren | 78.332 |
| Placebo | 76.609 |
Spirometry was used to assess pulmonary function by measuring the percentage of predicted function, which was determined on the basis of the height value obtained at the same study visit, for FEV1 (the amount of air that can be exhaled in 1 second). Spirometry was assessed by using current guidelines of the American Thoracic Society (ATS) and European Respiratory Society (ERS). The percentage of change in percent-predicted of FEV1 was calculated as follows: ([percent-predicted FEV1-Baseline percent-predicted FEV1]/Baseline percent-predicted FEV1)*100. Baseline was the average of percent-predicted FEV1 at screening and randomization. A negative change from Baseline indicates that percent-predicted of FEV1 decreased. (NCT00803205)
Timeframe: End of Treatment (EOT) (Week 48)
| Intervention | percent change (Mean) |
|---|---|
| Ataluren | -2.534 |
| Placebo | -5.500 |
Spirometry was used to assess pulmonary function by measuring the percentage of predicted function, which was determined on the basis of the height value obtained at the same study visit, for FVC (the amount of air that can be exhaled after taking a deep breath). Spirometry was assessed by using current guidelines of the ATS and ERS. The percentage of change in percent-predicted of FVC was calculated as follows: ((percent-predicted FVC-Baseline percent-predicted FVC)/Baseline percent-predicted FVC)*100. Baseline was the average of percent-predicted FVC at screening and randomization. A negative change from Baseline indicates that percent-predicted of FVC decreased. (NCT00803205)
Timeframe: EOT (Week 48)
| Intervention | percent change (Mean) |
|---|---|
| Ataluren | -2.139 |
| Placebo | -3.484 |
Spirometry was used to assess pulmonary function by measuring the percentage of predicted function, which was determined on the basis of the height value obtained at the same study visit, for FEV1 (the amount of air that can be exhaled in 1 second). Spirometry was assessed by using current guidelines of the American Thoracic Society (ATS) and European Respiratory Society (ERS). Baseline was the average of percent-predicted FEV1 at screening and randomization. (NCT00803205)
Timeframe: Baseline (Week 1)
| Intervention | percentage of predicted FEV1 (Mean) |
|---|---|
| Ataluren | 62.092 |
| Placebo | 60.232 |
During treatment, any disruption in the activities of daily living, such as missed school or work, was documented if it was due to an exacerbation-like episode. Participants and caregivers recorded all disruptions in an electronic diary. The rate of disruptions was defined as the total days with disruptions to daily living divided by the total study duration. (NCT00803205)
Timeframe: Baseline up to EOT (Week 48)
| Intervention | days with disruptions per study (Mean) |
|---|---|
| Ataluren | 0.037 |
| Placebo | 0.047 |
A Respiratory Event Form, which collected data on various signs, symptoms, and effects for each event, was completed by the Investigator when informed by the participant of a respiratory event. Pulmonary exacerbations were assessed by using the modified Fuchs' criteria, which defines an exacerbation as a respiratory event requiring treatment with parenteral antibiotics for any 4 of the following 12 symptoms, with or without intravenous antibiotics: change in sputum; new or increased hemoptysis; increased cough; increased dyspnea; fatigue; temperature >38°C; anorexia; sinus pain; change in sinus discharge; change in physical examination of the chest; decrease in pulmonary function by 10% or more from a previously recorded value; or radiographic changes indicative of pulmonary function. The 48-week exacerbation rate was determined by adding the weekly rates for each arm and dividing the sum by 48. (NCT00803205)
Timeframe: Baseline to EOT (Week 48)
| Intervention | exacerbations (Mean) |
|---|---|
| Ataluren | 1.42 |
| Placebo | 1.78 |
"Patient-reported data were obtained from the participant's electronic daily diary, which was completed by the participant or the caregiver. During study treatment, the electronic daily diary was to be completed by the participant or caregiver each day for each dose. For each participant, compliance is described in terms of the percentage of study drug actually taken. All calculations were based on the records of the first dose date to the last dose date. To differentiate dose strengths while maintaining the blind, each kit had a unique kit number and had prominent lettering A and B. Each kit contained 65 packets of 1 of the dose strengths (125, 250, or 1000 mg or matching placebo). Labeling for active drug and placebo was identical." (NCT00803205)
Timeframe: Baseline up to EOT (Week 48)
| Intervention | percent of doses taken (Median) |
|---|---|
| Ataluren | 71.48 |
| Placebo | 69.27 |
The frequency of awake cough was measured using the LifeShirt, which incorporates motion-sensing transducers, electrodes, a microphone, and a 3-axis accelerometer into a lightweight vest. The rate was determined by dividing the total number of coughs by 24 (the number of hours of the observation period). Baseline was the latest, valid assessment prior to the treatment. A negative change from Baseline indicates that coughing decreased. (NCT00803205)
Timeframe: Baseline, EOT (Week 48)
| Intervention | coughs/hour (Mean) | |
|---|---|---|
| Baseline | Change From Baseline | |
| Ataluren | 28.218 | -0.595 |
| Placebo | 24.472 | 0.882 |
Participants were weighed, and the weight was recorded at Baseline and then every 8 weeks during the treatment period. Baseline was the latest valid assessment prior to the treatment. A positive change from Baseline indicates that weight increased. (NCT00803205)
Timeframe: Baseline, EOT (Week 48)
| Intervention | kg (Mean) | |
|---|---|---|
| Baseline | Change From Baseline | |
| Ataluren | 53.46 | 0.87 |
| Placebo | 56.01 | 0.83 |
Sweat was collected, from each arm, by using pilocarpine iontophoresis. The chloride concentration in the sweat was quantified for each arm by using standard laboratory methods. Tests were also considered valid if the sweat collection time was ≤35 minutes; tests with longer collection times were also considered valid if extra time was needed to obtain sufficient volume (≥15uL) for analysis. For analysis purposes, the average of the values from each arm were computed. If the assessment was valid and/or available in only 1 arm, this value was used as if it were the average of both arms. The method used was consistent with the CFFT-TDN guidelines. Baseline was the latest, valid assessment prior to the treatment. A negative change from Baseline indicates that sweat chloride concentration decreased. (NCT00803205)
Timeframe: Baseline, EOT (Week 48)
| Intervention | millimoles/L (Mean) | |
|---|---|---|
| Baseline | Change From Baseline | |
| Ataluren | 100.140 | -1.325 |
| Placebo | 96.586 | -0.619 |
Expression of CRP was measured in serum. Baseline was the latest valid assessment prior to the treatment. A positive change from Baseline indicates that CRP concentration increased. (NCT00803205)
Timeframe: Baseline, EOT (Week 48)
| Intervention | mg/liter (L) (Mean) | |
|---|---|---|
| Baseline | Change From Baseline | |
| Ataluren | 6.899 | 2.420 |
| Placebo | 7.037 | 2.031 |
Expression of IL-8 was measured in serum and in sputum. Sputum was spontaneously produced and tested by using standardized procedures developed by the Cystic Fibrosis Foundation Therapeutics, Inc. Therapeutics Development Network (CFFT-TDN). Baseline was the latest valid assessment prior to the treatment. A negative change from Baseline indicates that the concentration of IL-8 decreased. (NCT00803205)
Timeframe: Baseline, EOT (Week 48)
| Intervention | picograms/mL (Mean) | |||
|---|---|---|---|---|
| Serum, Baseline | Serum, Change From Baseline | Sputum, Baseline | Sputum, Change From Baseline | |
| Ataluren | 39.537 | -2.334 | 267629.93 | 28882.79 |
| Placebo | 55.845 | -16.197 | 250170.95 | 9957.24 |
Expression of neutrophil elastase was measured in sputum. Sputum was spontaneously produced and tested by using standardized procedures developed by the CFFT-TDN. Baseline was the latest valid assessment prior to the treatment. A positive change from Baseline indicates that the concentration of neutrophil elastase increased. (NCT00803205)
Timeframe: Baseline, EOT (Week 48)
| Intervention | ug/mL (Mean) | |
|---|---|---|
| Baseline | Change From Baseline | |
| Ataluren | 183.64 | 5.45 |
| Placebo | 227.35 | -8.67 |
The CFQ-R consists of 44 items, including generic scales of physical functioning, role functioning, vitality, health perceptions, emotional functioning, and social functioning, and CF-specific scales of respiratory and digestive symptoms, body image, eating disturbances, and treatment burden. Each domain score ranges from 1 to 4. Scores were linearly transformed to a 0 to 100 scale, with higher scores indicating better health. Domain scores were calculated by using the following formula: 100 * (sum of responses - minimum possible sum)/ (maximum possible sum - minimum possible sum). The minimum possible sum = number of questions * 1; the maximum possible = the number of questions * 4. Baseline was the latest, valid assessment prior to the treatment. A negative change from Baseline indicates that health has worsened. Participants may have switched age groups during the study. (NCT00803205)
Timeframe: Baseline, EOT (Week 48)
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| Aged 6-13 years, Baseline | Aged 6-13 years, Change From Baseline | Age ≥14 years , Baseline | Age ≥14 years, Change From Baseline | |
| Ataluren | 77.78 | -0.69 | 70.06 | -2.81 |
| Placebo | 79.49 | -3.57 | 65.95 | -3.32 |
Lungs were imaged by using non-contrast, spiral CT. The total lung score for each CT scan was established by the sum of 5 characteristics from the Brody scoring system, with scores ranging from 0 to 40.5, with lower scores indicating better lung function. The characteristics scored were bronchiectasis (score range 0 - 12), mucus plugging (score range 0- 6), peribronchial thickening (score range 0 - 9), parenchyma (score range 0 - 9), and hyperinflation (score range 0 - 4.5). Baseline was the latest valid assessment prior to the treatment. A positive change from Baseline indicates that lung function worsened. (NCT00803205)
Timeframe: Baseline, EOT (Week 48)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | Change From Baseline | |
| Ataluren | 9.531 | 0.282 |
| Placebo | 9.619 | 0.560 |
TEPD was assessed in each nostril using standardized equipment, techniques, and solutions. Assessments were made on the nasal epithelium cells lining the inferior turbinate. Warmed solutions of Ringer's solution, amiloride, chloride-free gluconate, isoproterenol, and adenosine triphosphate (ATP) were perfused for ≥3-minute sequentially through a nasal catheter while a voltage tracing was recorded. Total chloride transport was computed for each nostril. The total chloride transport values were calculated by subtracting the voltages at the end of a perfusion from the voltage at the end of an earlier perfusion (isoproterenol - amiloride). The average of the values for each nostril was computed. If the assessment was available in only 1 nostril, this value was used as if it were the average of both nostrils. Baseline was the latest, valid assessment prior to the treatment. A positive change from Baseline indicates that nasal chloride transport increased. (NCT00803205)
Timeframe: Baseline, EOT (Week 48)
| Intervention | millivolts (Mean) | |
|---|---|---|
| Baseline | Change From Baseline | |
| Ataluren | 1.578 | 0.312 |
| Placebo | 1.950 | 0.139 |
Blood samples were drawn immediately before administration of the first daily dose (dose taken with breakfast) of study drug and 2 hours after the first daily dose. Whenever possible, the pre-dose sample was to be obtained within 15 minutes of drug administration. Participants in the Placebo arm did not receive Ataluren and are not included in this Outcome Measure. (NCT00803205)
Timeframe: Predose and 2 Hours Postdose at Week 1, Week 16, Week 32, EOT (Week 48)
| Intervention | micrograms/milliliter (ug/mL) (Median) | |||||||
|---|---|---|---|---|---|---|---|---|
| Week 1 Predose | Week 1 Postdose | Week 16 Predose | Week 16 Postdose | Week 32 Predose | Week 32 Postdose | Week 48 Predose | Week 48 Postdose | |
| Ataluren | 0 | 14.100 | 4.350 | 11.900 | 4.630 | 13.400 | 3.970 | 10.500 |
A TEAE was any untoward medical occurrence in a participant who received study drug without regard to possibility of causal relationship that occurred or worsened in the period extending from first dose of study drug to 4 weeks after the last dose of study drug. A serious adverse event (SAE) was an AE resulting in any of the following outcomes or deemed significant for any other reason: death; initial or prolonged inpatient hospitalization; life-threatening experience (immediate risk of dying); persistent or significant disability/incapacity; congenital anomaly. AEs included both SAEs and non-serious AEs. AE severity was graded as follows: Grade 1: mild; Grade 2: moderate; Grade 3: severe; Grade 4: life-threatening; Grade 5: fatal. A TEAE was considered related if in the opinion of the Investigator it was possibly or probably caused by the study drug. A summary of other non-serious AEs and all SAEs, regardless of causality is located in the Adverse Events module. (NCT00803205)
Timeframe: Baseline up to 4 Weeks Post-Treatment (Week 52) or Premature Discontinuation (PD)
| Intervention | percent of participants (Number) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| At least 1 TEAE | Grade 1 TEAE | Grade 2 TEAE | Grade 3 TEAE | Grade 4 TEAE | Grade 5 TEAE | Unrelated TEAE | Unlikely related TEAE | Possibly related TEAE | Probably related TEAE | Discontinuation due to TEAE | Serious TEAE | |
| Ataluren | 98.3 | 15.0 | 67.5 | 15.8 | 0 | 0 | 25.0 | 32.5 | 28.3 | 12.5 | 6.7 | 37.5 |
| Placebo | 97.5 | 16.9 | 55.1 | 25.4 | 0 | 0 | 35.6 | 26.3 | 29.7 | 5.9 | 2.5 | 40.7 |
During treatment, any intervention including hospitalization or use of oral, inhaled, or intravenous antibiotics was documented if it was due to an exacerbation-like episode. Participants and caregivers recorded interventions in an electronic diary. The rate of interventions was defined as the total days with interventions divided by the total study duration. (NCT00803205)
Timeframe: Baseline up to EOT (Week 48)
| Intervention | days with interventions per study (Mean) | |
|---|---|---|
| Hospitalization | Use of Antibiotics | |
| Ataluren | 0.010 | 0.220 |
| Placebo | 0.021 | 0.245 |
"Study drug compliance was assessed by using a Pharmacy Subject Study Drug Accountability Log (completed by the investigational site personnel). The rate of compliance was defined as 100 * (number of sachets taken/number of planned sachets) during the study. All calculations were based on the records of the first dose date to the last dose date. To differentiate dose strengths while maintaining the blind, each kit had a unique kit number and had prominent lettering A and B. Each kit contained 65 packets of 1 of the dose strengths (125, 250, or 1000 mg or matching placebo). Labeling for active drug and placebo was identical." (NCT00803205)
Timeframe: Baseline up to EOT (Week 48)
| Intervention | percent of doses taken (Median) | |
|---|---|---|
| Drug Kit A | Drug Kit B | |
| Ataluren | 90.149 | 90.830 |
| Placebo | 85.119 | 86.614 |
Death before hospital discharge, censored at 30 days after enrollment (NCT02547779)
Timeframe: 30 days after enrollment censored at hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride | 408 |
| Balanced Crystalloids | 400 |
The primary outcome was the proportion of patients who met one or more criteria for a major adverse kidney event within 30 days - the composite of death, new receipt of renal-replacement therapy, or persistent renal dysfunction (defined as a final inpatient creatinine value ≥200% of the baseline value) - all censored at hospital discharge or 30 days after enrollment, whichever came first. (NCT02547779)
Timeframe: 30 days after enrollment censored at hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride | 551 |
| Balanced Crystalloids | 524 |
Dialysis free survival to day 28 will be defined as the number of days alive and without dialysis receipt to day 28 after enrollment, assuming a patient survives for at least two consecutive calendar days after last receipt of dialysis and remains free of dialysis. If the patient is receiving dialysis at day 28 or dies prior to day 28, VFD will be 0. (NCT02345486)
Timeframe: 28 days
| Intervention | days (Median) |
|---|---|
| 0.9% Sodium Chloride | 28.0 |
| Physiologically Balanced Fluid | 28.0 |
highest serum chloride (mmol/L) during admission to the intensive care unit, censored at 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | mmol/L (Median) |
|---|---|
| 0.9% Sodium Chloride | 109 |
| Physiologically Balanced Fluid | 108 |
Highest serum sodium concentration (mmol/L) during admission to the intensive care unit, censored at 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | mmol/L (Median) |
|---|---|
| 0.9% Sodium Chloride | 141 |
| Physiologically Balanced Fluid | 141 |
Death prior to the earlier of hospital discharge or day 30 (NCT02345486)
Timeframe: 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride | 68 |
| Physiologically Balanced Fluid | 72 |
Incidence of stage II or III acute kidney injury by Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury criteria, censored at 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride | 129 |
| Physiologically Balanced Fluid | 135 |
Incidence of hyperchloremia defined as a serum chloride greater than or equal to 110 mmol/L (NCT02345486)
Timeframe: 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride | 171 |
| Physiologically Balanced Fluid | 171 |
Incidence of severe hypochloremia defined as a serum chloride less than 90mmol/L (NCT02345486)
Timeframe: 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride | 34 |
| Physiologically Balanced Fluid | 32 |
Increase in serum creatinine during hospitalization, censored at 30 days Change from baseline to highest value, median (IQR), mg/dl (NCT02345486)
Timeframe: 30 days
| Intervention | mg/dL (Median) |
|---|---|
| 0.9% Sodium Chloride | 0.07 |
| Physiologically Balanced Fluid | 0.07 |
ICU-free days to 28 days after enrollment will be defined as the number of days alive and not admitted to an intensive care unit service after the patient's final discharge from the intensive care unit before 28 days. If the patient is admitted to an intensive care unit service at day 28 or dies prior to day 28, ICU-free days will be 0. (NCT02345486)
Timeframe: 28 days
| Intervention | days (Median) |
|---|---|
| 0.9% Sodium Chloride | 25.1 |
| Physiologically Balanced Fluid | 25.2 |
Lowest serum bicarbonate concentration (mmol/L) during admission to the intensive care unit, censored at 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | mmol/L (Median) |
|---|---|
| 0.9% Sodium Chloride | 19 |
| Physiologically Balanced Fluid | 19 |
Receipt of new renal replacement therapy after the first study day, censored at 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride | 14 |
| Physiologically Balanced Fluid | 24 |
Number of contraindications to assigned study fluid identified by providers, censored at 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | Orders for intravenous crystalloid (Count of Units) |
|---|---|
| 0.9% Sodium Chloride | 28 |
| Physiologically Balanced Fluid | 66 |
Incidence of Major Adverse Kidney Events by 30 days -- a composite outcome defined as one or more of the following: death, new use of renal replacement therapy, or persistence of renal dysfunction at hospital discharge or at 30 days (defined as an increase in serum creatinine ≥ 200% from baseline) (NCT02345486)
Timeframe: 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride | 112 |
| Physiologically Balanced Fluid | 128 |
Highest creatinine value in the first 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | mg/dL (Median) |
|---|---|
| 0.9% Sodium Chloride | 1.19 |
| Physiologically Balanced Fluid | 1.19 |
Persistence of renal dysfunction at hospital discharge or at 30 days (defined as an increase in serum creatinine ≥ 200% from baseline) (NCT02345486)
Timeframe: 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride | 59 |
| Physiologically Balanced Fluid | 76 |
Proportion of total intravenous isotonic crystalloid administered during admission to the intensive care unit that is 0.9% sodium chloride, censored at 30 days. The primary outcome was the proportion of intravenous isotonic crystalloid administered in the ICU that was saline. This was a continuous variable calculated for each patient as the volume of saline received divided by volume of saline received plus volume of balanced crystalloids received with a range from 0.0 (no saline received) to 1.0 (only saline received). (NCT02345486)
Timeframe: 30 days
| Intervention | Percentage of fluid that was saline (Mean) |
|---|---|
| 0.9% Sodium Chloride | 91.2 |
| Physiologically Balanced Fluid | 21.0 |
Proportion of total intravenous isotonic crystalloid administered during admission to the intensive care unit that is either Lactated ringers or Plasmalyte-A, censored at 30 days. (NCT02345486)
Timeframe: 30 days
| Intervention | Percentage of fluid that was balanced (Mean) |
|---|---|
| 0.9% Sodium Chloride | 8.8 |
| Physiologically Balanced Fluid | 78.8 |
Total volume of packed red blood cells, platelets, and fresh frozen plasma administered during admission to the intensive care unit, censored at 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | milliliters (Median) |
|---|---|
| 0.9% Sodium Chloride | 0 |
| Physiologically Balanced Fluid | 0 |
Total volume of intravenous colloid administration (excluding blood products) during admission to the intensive care unit, censored at 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | milliliters (Median) |
|---|---|
| 0.9% Sodium Chloride | 0 |
| Physiologically Balanced Fluid | 0 |
Total volume of intravenous fluid administration during admission to the intensive care unit, censored at 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | milliliters (Median) |
|---|---|
| 0.9% Sodium Chloride | 2000 |
| Physiologically Balanced Fluid | 2125 |
Total volume of intravenous isotonic crystalloid administration during admission to the intensive care unit, censored at 30 days (NCT02345486)
Timeframe: 30 days
| Intervention | mL (Median) |
|---|---|
| 0.9% Sodium Chloride | 1424 |
| Physiologically Balanced Fluid | 1617 |
Ventilator-free days to day 28 will be defined as the number of days alive and with unassisted breathing to day 28 after enrollment, assuming a patient survives for at least two consecutive calendar days after initiating unassisted breathing and remains free of assisted breathing. If a patient returns to assisted breathing and subsequently achieves unassisted breathing prior to day 28, VFD will be counted from the end of the last period of assisted breathing to day 28. If the patient is receiving assisted ventilation at day 28 or dies prior to day 28, VFD will be 0. (NCT02345486)
Timeframe: 28 days
| Intervention | days (Median) |
|---|---|
| 0.9% Sodium Chloride | 28.0 |
| Physiologically Balanced Fluid | 28.0 |
Death before hospital discharge, censored at 30 days after enrollment (NCT02444988)
Timeframe: 30 days after enrollment censored at hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride (Saline) | 467 |
| Balanced Crystalloid | 418 |
The primary outcome was the proportion of patients who met one or more criteria for a major adverse kidney event within 30 days - the composite of death, new receipt of renal-replacement therapy, or persistent renal dysfunction (defined as a final inpatient creatinine value ≥200% of the baseline value) - all censored at hospital discharge or 30 days after enrollment, whichever came first. (NCT02444988)
Timeframe: 30 days after enrollment censored at hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| 0.9% Sodium Chloride (Saline) | 659 |
| Balanced Crystalloid | 615 |
12 reviews available for chlorine and Acute Kidney Injury
| Article | Year |
|---|---|
Managing Chloride and Bicarbonate in the Prevention and Treatment of Acute Kidney Injury.
Topics: Acidosis; Acute Kidney Injury; Bicarbonates; Chlorides; Crystalloid Solutions; Humans | 2019 |
Low- versus High-Chloride Content Intravenous Solutions for Perioperative Patients: A Systematic Review and Meta-Analysis.
Topics: Acute Kidney Injury; Administration, Intravenous; Chlorides; Fluid Therapy; Humans; Randomized Contr | 2021 |
"I don't get no respect": the role of chloride in acute kidney injury.
Topics: Acute Kidney Injury; Animals; Chlorides; Glomerular Filtration Rate; Humans; Risk Factors | 2019 |
Epithelial transport during septic acute kidney injury.
Topics: Acute Kidney Injury; Animals; Chlorides; Epithelial Cells; Humans; Ion Transport; Sepsis | 2014 |
[Severe dehydration and August 2003 heat wave in a cohort of adults with cystic fibrosis].
Topics: Acute Kidney Injury; Adult; Chlorides; Cystic Fibrosis; Dehydration; Disease Outbreaks; Disease Susc | 2005 |
Measurement of urine electrolytes: clinical significance and methods.
Topics: Acute Kidney Injury; Alkalosis; Bartter Syndrome; Chlorides; Electrolytes; Humans; Hypokalemia; Hypo | 1981 |
[Voluntary barium poisoning].
Topics: Acute Kidney Injury; Barium Compounds; Chlorides; Humans; Hypokalemia; Male; Middle Aged; Neuromuscu | 1993 |
[Shock kidney (author's transl)].
Topics: Acute Kidney Injury; Angiotensin II; Animals; Chlorides; Glomerular Filtration Rate; Humans; Juxtagl | 1978 |
Acute renal failure in the intensive care unit. Part 1.
Topics: Acute Kidney Injury; Antigens; Chlorides; Creatinine; Critical Care; Diagnostic Imaging; Humans; Kid | 1988 |
Nonoliguric acute renal failure.
Topics: Acute Kidney Injury; Chlorides; Glomerular Filtration Rate; Humans; Kidney Diseases; Kidney Tubular | 1985 |
[Abnormalities and interrelations of biochemical indicators in kidney failure].
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Amino Acids; Blood Urea Nitrogen; Calcium; Carbohydrate | 1968 |
[Disorders of water-electrolyte blaance in kidney diseases].
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Acute Kidney Injury; Anuria; Bicarbonates; Chlorides | 1968 |
10 trials available for chlorine and Acute Kidney Injury
| Article | Year |
|---|---|
Effect of Saline vs Gluconate/Acetate-Buffered Solution vs Lactate-Buffered Solution on Serum Chloride Among Children in the Pediatric Intensive Care Unit: The SPLYT-P Randomized Clinical Trial.
Topics: Acute Kidney Injury; Adult; Child; Child, Preschool; Chlorides; Critical Illness; Fluid Therapy; Glu | 2023 |
Impact of continuous hypertonic (NaCl 20%) saline solution on renal outcomes after traumatic brain injury (TBI): a post hoc analysis of the COBI trial.
Topics: Acute Kidney Injury; Brain Injuries, Traumatic; Chlorides; Humans; Kidney; Saline Solution; Saline S | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Acute Kidney Injury; Adult; Aged; Albumins; Alloys; Amides; Amino Acids; Animals; Antineoplastic Com | 2023 |
Effect of 0.9% NaCl compared to plasma-lyte on biomarkers of kidney injury, sodium excretion and tubular transport proteins in patients undergoing primary uncemented hip replacement - a randomized trial.
Topics: Acute Kidney Injury; Aged; Arthroplasty, Replacement, Hip; Biomarkers; Chlorides; Double-Blind Metho | 2021 |
Effect of 3% saline and furosemide on biomarkers of kidney injury and renal tubular function and GFR in healthy subjects - a randomized controlled trial.
Topics: Acute Kidney Injury; Adult; Aldosterone; Aquaporin 2; Biomarkers; Chlorides; Female; Furosemide; Glo | 2019 |
Safety evaluation of a trial of lipocalin-directed sodium bicarbonate infusion for renal protection in at-risk critically ill patients.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; Bicarbonates; Chlorides; Critical Illness; Double-B | 2013 |
Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial.
Topics: Acute Kidney Injury; Adolescent; Adult; Anti-Bacterial Agents; Child; Chlorides; Codon, Nonsense; Cy | 2014 |
Dyschloremia Is a Risk Factor for the Development of Acute Kidney Injury in Critically Ill Patients.
Topics: Acute Kidney Injury; Adult; Aged; Chlorides; Critical Illness; Female; Humans; Male; Middle Aged; Re | 2016 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Female; Fluid Therapy; Hospital Mortality; Hospita | 2012 |
Bumetanide, a new diuretic.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Benzoates; Bumetanide; Butylamines; Chlorides; Clinica | 1974 |
146 other studies available for chlorine and Acute Kidney Injury
| Article | Year |
|---|---|
Hyperchloremia is associated with poor renal outcome after coronary artery bypass grafting.
Topics: Acute Kidney Injury; Aged; Chlorides; Coronary Artery Bypass; Coronary Artery Disease; Female; Human | 2021 |
Clinically Distinct Subtypes of Acute Kidney Injury on Hospital Admission Identified by Machine Learning Consensus Clustering.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Bicarbonates; Chlorides; Cluster Analysis; Cons | 2021 |
The relationship between hyperchloremia and acute kidney injury in pediatric diabetic ketoacidosis and its impact on clinical outcomes.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Child; Chlorides; Creatinine; Cross-Sectional Studies; Dia | 2022 |
Association of hypochloremia with mortality among patients requiring continuous renal replacement therapy.
Topics: Acute Kidney Injury; Chlorides; Continuous Renal Replacement Therapy; Critical Illness; Humans; Logi | 2023 |
Incidence and factors associated with acute kidney injury among children with type 1 diabetes hospitalized with diabetic ketoacidosis: A prospective study.
Topics: Acute Kidney Injury; Child; Chlorides; Creatinine; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; | 2022 |
[Sodium-chlorine difference as a prognostic predictor in adult patients diagnosed with COVID-19].
Topics: Acute Kidney Injury; Adult; Chlorides; Chlorine; COVID-19; Critical Illness; Hospital Mortality; Hum | 2022 |
Association between C-reactive protein and all-cause mortality among critically ill patients with acute kidney injury.
Topics: Acute Kidney Injury; C-Reactive Protein; Chlorides; Critical Illness; Hospital Mortality; Humans; In | 2022 |
Sodium chlorite poisoning: a case of severe methaemoglobinaemia and dialysis-requiring kidney injury.
Topics: Acute Kidney Injury; Chlorides; Humans; Kidney; Methemoglobinemia; Poisoning; Renal Dialysis | 2022 |
Association between serum chloride levels with mortality in critically ill patients with acute kidney injury: An observational multicenter study employing the eICU database.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Chlorides; Critical Illness; Humans; Intensive Care Units; | 2022 |
Plasma Clearance of Intravenously Infused Adrenomedullin in Rats with Acute Renal Failure.
Topics: Acute Kidney Injury; Adrenomedullin; Animals; Calcitonin Receptor-Like Protein; Chlorides; Humans; M | 2022 |
Lower serum chloride concentrations are associated with an increased risk of death in ICU patients with acute kidney injury: an analysis of the MIMIC-IV database.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Hospitalization; Humans; Intensive Care Units; Ret | 2023 |
Hyperchloremia and association with acute kidney injury in critically ill children.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Adult; Child; Chlorides; Critical Illness; Hospitalization | 2023 |
Hyperchloremia and association with acute kidney injury in critically ill children.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Adult; Child; Chlorides; Critical Illness; Hospitalization | 2023 |
Hyperchloremia and association with acute kidney injury in critically ill children.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Adult; Child; Chlorides; Critical Illness; Hospitalization | 2023 |
Hyperchloremia and association with acute kidney injury in critically ill children.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Adult; Child; Chlorides; Critical Illness; Hospitalization | 2023 |
Hyperchloremia and association with acute kidney injury in critically ill children.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Adult; Child; Chlorides; Critical Illness; Hospitalization | 2023 |
Hyperchloremia and association with acute kidney injury in critically ill children.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Adult; Child; Chlorides; Critical Illness; Hospitalization | 2023 |
Hyperchloremia and association with acute kidney injury in critically ill children.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Adult; Child; Chlorides; Critical Illness; Hospitalization | 2023 |
Hyperchloremia and association with acute kidney injury in critically ill children.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Adult; Child; Chlorides; Critical Illness; Hospitalization | 2023 |
Hyperchloremia and association with acute kidney injury in critically ill children.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Adult; Child; Chlorides; Critical Illness; Hospitalization | 2023 |
INCREASE IN CHLORIDE IS ASSOCIATED WITH MAJOR ADVERSE KIDNEY EVENTS IN CRITICALLY ILL PATIENTS.
Topics: Acute Kidney Injury; Adult; Aged; Chlorides; Critical Illness; Hospital Mortality; Humans; Intensive | 2023 |
INCREASE IN CHLORIDE IS ASSOCIATED WITH MAJOR ADVERSE KIDNEY EVENTS IN CRITICALLY ILL PATIENTS.
Topics: Acute Kidney Injury; Adult; Aged; Chlorides; Critical Illness; Hospital Mortality; Humans; Intensive | 2023 |
INCREASE IN CHLORIDE IS ASSOCIATED WITH MAJOR ADVERSE KIDNEY EVENTS IN CRITICALLY ILL PATIENTS.
Topics: Acute Kidney Injury; Adult; Aged; Chlorides; Critical Illness; Hospital Mortality; Humans; Intensive | 2023 |
INCREASE IN CHLORIDE IS ASSOCIATED WITH MAJOR ADVERSE KIDNEY EVENTS IN CRITICALLY ILL PATIENTS.
Topics: Acute Kidney Injury; Adult; Aged; Chlorides; Critical Illness; Hospital Mortality; Humans; Intensive | 2023 |
Association of hyperchloremia and acute kidney injury in pediatric patients with moderate and severe traumatic brain injury.
Topics: Acute Kidney Injury; Adult; Brain Injuries, Traumatic; Child; Child, Preschool; Chlorides; Female; H | 2023 |
Chloride, Sodium and Calcium Intake Are Associated with Mortality and Follow-Up Kidney Function in Critically Ill Patients Receiving Continuous Veno-Venous Hemodialysis-A Retrospective Study.
Topics: Acute Kidney Injury; Aged; Calcium; Chlorides; Continuous Renal Replacement Therapy; Critical Illnes | 2023 |
Effects of serum sodium and chloride levels in the outcome of critically ill pediatric patients in the post-operative period of liver transplantation.
Topics: Acute Kidney Injury; Brazil; Child; Chlorides; Critical Illness; Humans; Liver Transplantation; Post | 2023 |
Acute mercuric chloride poisoning at a potentially lethal dose ended with survival: symptoms, concentration in cerebrospinal fluid, treatment.
Topics: Acute Kidney Injury; Adult; Chlorides; Female; Humans; Mercuric Chloride; Mercury; Mercury Poisoning | 2023 |
Urinary chloride concentration as a prognostic marker in critically ill patients.
Topics: Acute Kidney Injury; Aged; Biomarkers; Chlorides; Critical Illness; Down-Regulation; Female; Hospita | 2020 |
Effects of hyperchloremia on renal recovery in critically ill children with acute kidney injury.
Topics: Acute Kidney Injury; Adolescent; Bicarbonates; Child; Child, Preschool; Chlorides; Female; Humans; I | 2020 |
Reply: Assessment of Acute Kidney Injury in Neurologically Injured Patients Receiving Hypertonic Sodium Chloride: Does Chloride Load Matter?
Topics: Acute Kidney Injury; Chlorides; Humans; Saline Solution, Hypertonic; Sodium; Sodium Chloride | 2021 |
Comment: Assessment of Acute Kidney Injury in Neurologically Injured Patients Receiving Hypertonic Sodium Chloride: Does Chloride Load Matter?
Topics: Acute Kidney Injury; Chlorides; Humans; Saline Solution, Hypertonic; Sodium; Sodium Chloride | 2021 |
Dyschloremia is associated with failure to restore renal function in survivors with acute kidney injury: an observation retrospective study.
Topics: Acute Kidney Injury; Aged; Chlorides; Continuous Renal Replacement Therapy; Critical Illness; Female | 2020 |
Safety analysis regarding acute kidney injuries for chloride-restrictive intravenous fluid administration against that of chloride-liberal for patients admitted in the medical intensive care unit: A non-randomised retrospective (chrachl-mic) study.
Topics: Acute Kidney Injury; Chlorides; Critical Illness; Hospitalization; Humans; Intensive Care Units; Ret | 2021 |
The Perioperative Hyperchloremia Is Associated With Postoperative Acute Kidney Injury in Patients With off-Pump Coronary Artery Bypass Grafting: A Retrospective Study.
Topics: Acute Kidney Injury; Biomarkers; China; Chlorides; Coronary Artery Bypass, Off-Pump; Coronary Artery | 2020 |
Does Chloride Intake at the Early Phase of Septic Shock Resuscitation Impact on Renal Outcome?
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Chlorides; Critical Care; Female; Fluid Therapy; Hospi | 2021 |
Impact of chloride-rich crystalloids on sepsis-associated community-acquired acute kidney injury recovery in critically ill patients.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Chlorides; Cohort Studies; Critical Illness; Cr | 2022 |
Distinct phenotypes of hospitalized patients with hyperkalemia by machine learning consensus clustering and associated mortality risks.
Topics: Acute Kidney Injury; Bicarbonates; Chlorides; Cluster Analysis; Consensus; Humans; Hyperkalemia; Mac | 2022 |
Hyperchloremia and Postoperative Acute Kidney Injury in Adult Cardiac Patients: A Propensity-Matched Cohort Study.
Topics: Acute Kidney Injury; Adult; Chlorides; Cohort Studies; Female; Humans; Male; Postoperative Complicat | 2022 |
Protective effect of zinc preconditioning against renal ischemia reperfusion injury is dose dependent.
Topics: Acute Kidney Injury; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Chlorides; Co | 2017 |
Baseline Chloride Levels are Associated with the Incidence of Contrast-Associated Acute Kidney Injury.
Topics: Acute Kidney Injury; Biomarkers; Chlorides; Contrast Media; Creatinine; Female; Humans; Male; Middle | 2017 |
Urinary potassium excretion and its association with acute kidney injury in the intensive care unit.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Area Under Curve; Biomarkers; Chlor | 2018 |
Perioperative Hyperchloremia and its Association With Postoperative Acute Kidney Injury After Craniotomy for Primary Brain Tumor Resection: A Retrospective, Observational Study.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chlorides; Craniotomy; Female; | 2019 |
Hyperchloremia is associated with acute kidney injury in pediatric patients with septic shock.
Topics: Acute Kidney Injury; Child; Chlorides; Databases, Factual; Humans; Intensive Care Units; Retrospecti | 2018 |
Increase in chloride from baseline is independently associated with mortality in critically ill children.
Topics: Acute Kidney Injury; Adolescent; Age Factors; Child; Child, Preschool; Chlorides; Critical Illness; | 2018 |
Increase in serum chloride and chloride exposure are associated with acute kidney injury in moderately severe and severe acute pancreatitis patients.
Topics: Acute Kidney Injury; Adult; Aged; Chlorides; Cohort Studies; Female; Humans; Male; Middle Aged; Mult | 2019 |
Retrospective evaluation of paired plasma creatinine and chloride concentrations following hetastarch administration in anesthetized dogs (2002-2015): 244 cases.
Topics: Acute Kidney Injury; Anesthesia, General; Animals; Chlorides; Creatinine; Dogs; Female; Hydroxyethyl | 2019 |
Hyperchloremia and acute kidney injury: a retrospective observational cohort study on a general mixed medical-surgical not ICU-hospitalized population.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Chlorides; Cohort Studies; Female; Hospitalization; Hu | 2020 |
Chloride-restrictive fluid administration and incidence of acute kidney injury.
Topics: Acute Kidney Injury; Chlorides; Female; Fluid Therapy; Humans; Male | 2013 |
Chloride-restrictive fluid administration and incidence of acute kidney injury.
Topics: Acute Kidney Injury; Chlorides; Female; Fluid Therapy; Humans; Male | 2013 |
Chloride-restrictive fluid administration and incidence of acute kidney injury.
Topics: Acute Kidney Injury; Chlorides; Female; Fluid Therapy; Humans; Male | 2013 |
Chloride-restrictive fluid administration and incidence of acute kidney injury--reply.
Topics: Acute Kidney Injury; Chlorides; Female; Fluid Therapy; Humans; Male | 2013 |
Intravenous fluid therapy: saline versus mixed electrolyte and organic anion solutions.
Topics: Acute Kidney Injury; Cardioplegic Solutions; Chlorides; Digestive System Surgical Procedures; Female | 2013 |
The influence of taurine pretreatment on aluminum chloride induced nephrotoxicity in Swiss albino mice.
Topics: Acute Kidney Injury; Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Chlorides; Kidney | 2014 |
Higher serum chloride concentrations are associated with acute kidney injury in unselected critically ill patients.
Topics: Acute Kidney Injury; Biomarkers; China; Chlorides; Critical Illness; Female; Humans; Male; Middle Ag | 2013 |
A case of severe chlorite poisoning successfully treated with early administration of methylene blue, renal replacement therapy, and red blood cell transfusion: case report.
Topics: Acute Kidney Injury; Anemia, Hemolytic; Chlorides; Combined Modality Therapy; Disseminated Intravasc | 2014 |
Chloride-liberal fluids are associated with acute kidney injury after liver transplantation.
Topics: Acute Kidney Injury; Adult; Aged; Chlorides; Female; Fluid Therapy; Humans; Liver Transplantation; M | 2014 |
Chloride-liberal vs. chloride-restrictive intravenous fluid administration and acute kidney injury: an extended analysis.
Topics: Acute Kidney Injury; Chlorides; Female; Fluid Therapy; Humans; Incidence; Infusions, Intravenous; In | 2015 |
The relationship of intravenous fluid chloride content to kidney function in patients with severe sepsis or septic shock.
Topics: Acute Kidney Injury; Aged; Chlorides; Creatinine; Female; Fluid Therapy; Humans; Length of Stay; Lin | 2015 |
Protective effect of resveratrol against aluminum chloride induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Chlorides; Creati | 2016 |
Urinary Strong Ion Difference as a Marker of Renal Dysfunction. A Retrospective Analysis.
Topics: Acute Kidney Injury; Aged; Biomarkers; Calcium; Chlorides; Creatinine; Critical Illness; Female; Hum | 2016 |
Hyperchloremic acidosis is associated with acute kidney injury after abdominal surgery.
Topics: Abdomen; Acid-Base Equilibrium; Acidosis; Acute Kidney Injury; Aged; Biomarkers; Chi-Square Distribu | 2017 |
Chloride content of solutions used for regional citrate anticoagulation might be responsible for blunting correction of metabolic acidosis during continuous veno-venous hemofiltration.
Topics: Acid-Base Equilibrium; Acidosis; Acute Kidney Injury; Aged; Aged, 80 and over; Anticoagulants; Bicar | 2016 |
Chloride Content of Fluids Used for Large-Volume Resuscitation Is Associated With Reduced Survival.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Adult; Aged; Chlorides; Female; Fluid Therapy; Humans; Ma | 2017 |
Fluid balance and chloride load in the first 24h of ICU admission and its relation with renal replacement therapies through a multicentre, retrospective, case-control study paired by APACHE-II.
Topics: Acute Kidney Injury; Aged; APACHE; Case-Control Studies; Chlorides; Female; Humans; Intensive Care U | 2017 |
Altered electrolyte handling of the choroid plexus in rats with glycerol-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Area Under Curve; Bumetanide; Chlorides; Choroid Plexus; Electrolytes; | 2010 |
An infant with alternating metabolic acidosis and alkalosis: question.
Topics: Acidosis; Acute Kidney Injury; Alkalosis; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane | 2012 |
Impaired renal function is associated with greater urinary strong ion differences in critically ill patients with metabolic acidosis.
Topics: Acidosis; Acute Kidney Injury; Aged; Chlorides; Creatinine; Female; Humans; Hydrogen-Ion Concentrati | 2012 |
Nephroprotective effect of Croton zambesicus root extract against gentimicin-induced kidney injury.
Topics: Acute Kidney Injury; Animals; Antioxidants; Biomarkers; Chlorides; Creatinine; Croton; Dogs; Female; | 2011 |
Comments on "Impaired renal function is associated with greater urinary strong ion differences in critically ill patients with metabolic acidosis".
Topics: Acidosis; Acute Kidney Injury; Chlorides; Female; Humans; Male | 2012 |
A case of sodium chlorite toxicity managed with concurrent renal replacement therapy and red cell exchange.
Topics: Accidents; Acute Kidney Injury; Aged; Anuria; Chlorides; Disseminated Intravascular Coagulation; Ery | 2013 |
Saving the kidneys by sparing intravenous chloride?
Topics: Acute Kidney Injury; Chlorides; Female; Fluid Therapy; Humans; Male | 2012 |
[Relative hypochloremia in secondary kidney tubule insufficiency].
Topics: Acid-Base Imbalance; Acute Kidney Injury; Chlorides; Humans; Kidney Tubules; Urologic Diseases; Wate | 1957 |
FLUID AND ELECTROLYTE THERAPY IN SURGERY: A RATIONAL APPROACH.
Topics: Acute Kidney Injury; Calcium; Chlorides; Colitis; Colitis, Ulcerative; Diarrhea; Humans; Iatrogenic | 1964 |
[RISING OF THE SERUM TRANSAMINASE ACTIVITY IN KIDNEY DAMAGE CAUSED BY HORMONES OR HGCL-2 SOLUTION IN RATS].
Topics: Acute Kidney Injury; Aspartate Aminotransferases; Blood; Chlorides; Estrogens; Kidney; Kidney Diseas | 1964 |
[ON THE PATHOMECHANISM OF THE SHOCK KIDNEY. 3. EFFECT OF SUBLIMATE ON THE TUBULAR FUNCTION].
Topics: Acute Kidney Injury; Chlorides; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Mercuric Chl | 1964 |
Butein ameliorates renal concentrating ability in cisplatin-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Aquaporin 2; Aquaporins; Blotting, Western; Cha | 2004 |
The effect of oculo-acupuncture on recovery from ethylene glycol-induced acute renal injury in dogs.
Topics: Acupuncture Points; Acupuncture Therapy; Acute Kidney Injury; Animals; Blood Urea Nitrogen; Chloride | 2007 |
Kidney in sepsis.
Topics: Acute Kidney Injury; Animals; Chlorides; Cytokines; Humans; Kidney; Mice; Sepsis | 2007 |
Acid-base balance in combined severe hepatic and renal failure: a quantitative analysis.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Acute Kidney Injury; Adult; Aged; Alanine Transaminase; Bil | 2008 |
[Studies on radiation renal damages. 3. Changes of blood pressure and serum biochemical and histological pictures following x-ray irradiation to the kidney of adult dog].
Topics: Acute Kidney Injury; Animals; Blood Pressure; Calcium; Chlorides; Dogs; Kidney; Nephrectomy; Potassi | 1966 |
[A comparative clinical investigation of the diuretic furosemide].
Topics: Acute Kidney Injury; Benzothiadiazines; Chlorides; Diuretics; Eclampsia; Edema; Female; Furosemide; | 1966 |
Hypersecreting villous rectal papilloma leading to excessive electrolyte-fluid losses and acute renal failure.
Topics: Acute Kidney Injury; Calcium; Chlorides; Colonic Neoplasms; Diarrhea; Humans; Male; Middle Aged; Muc | 1967 |
Liver, kidney, and central nervous system toxicity of aluminum given intraperitoneally to rats: a multiple-dose subchronic study using aluminum nitrilotriacetate.
Topics: Acetates; Acidosis; Acute Kidney Injury; Alum Compounds; Aluminum; Aluminum Chloride; Aluminum Compo | 1984 |
Renal function and mercury level in rats with mercuric chloride nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Chlorides; Female; Kidney; Kidney Cortex; Mercuric Chloride; Mercury; | 1980 |
Tubular handling of bicarbonate in dogs with experimental renal failure.
Topics: Acute Kidney Injury; Animals; Bicarbonates; Chlorides; Disease Models, Animal; Dogs; Female; Kidney | 1984 |
Urinary chloride concentration in acute renal failure.
Topics: Acidosis; Acute Kidney Injury; Blood Urea Nitrogen; Chlorides; Creatinine; Humans; Kidney Tubular Ne | 1984 |
Effect of furosemide on acute renal failure in dogs; induced by mercuric chloride.
Topics: Acute Kidney Injury; Animals; Chlorides; Dogs; Furosemide; Ischemia; Kidney; Kidney Cortex; Mercury; | 1980 |
Maintenance hemodialysis in end-stage renal disease associated with spinal cord injury.
Topics: Acute Kidney Injury; Adult; Aged; Bicarbonates; Blood Pressure; Body Weight; Chlorides; Heart Rate; | 1982 |
Acute renal failure associated with barium chloride poisoning.
Topics: Acute Kidney Injury; Barium; Barium Compounds; Chlorides; Humans; Male; Middle Aged; Suicide, Attemp | 1981 |
Effect of the selective A1 adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine on acute renal dysfunction induced by Escherichia coli endotoxin in rats.
Topics: Acute Kidney Injury; Animals; Chlorides; Endotoxins; Escherichia coli; Inulin; Kidney Function Tests | 1993 |
Acute sodium chlorite poisoning associated with renal failure.
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Chlorides; Disseminated Intravascular Coagulation; He | 1993 |
[The effects of acute administration of cadmium chloride on renal hemodynamics in rats].
Topics: Acute Kidney Injury; Animals; Blood Pressure; Cadmium; Cadmium Chloride; Chlorides; Glomerular Filtr | 1993 |
Sodium-chloride-induced protection in nephrotoxic acute renal failure: independence from renin.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Chlorides; Diet; Female; Kidney Cortex; Mercury; | 1979 |
Postoperative mercury poisoning.
Topics: Abdominal Neoplasms; Acute Kidney Injury; Chlorides; Humans; Mercury; Mercury Poisoning; Peritoneal | 1979 |
[Regeneration of the proximal kidney tubules after sublimate-induced necrosis in the rate. Scanning electron microscopic studies].
Topics: Acute Kidney Injury; Animals; Chlorides; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; M | 1979 |
Ligandinuria in nephrotoxic acute tubular necrosis.
Topics: Acute Kidney Injury; Animals; Chlorides; Female; Glutathione Transferase; Kidney Tubular Necrosis, A | 1977 |
Systemic hemodynamics in nephrotoxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Cardiac Output; Chlorides; Hemodynamics; Kidney; Male; Mercury; Plasma | 1978 |
Clinical disorders of sodium, potassium, chloride, and sulfur metabolism. Diagnostic approach in children.
Topics: Acute Kidney Injury; Child; Chlorides; Creatinine; Dehydration; Diarrhea; Electrolytes; Fluid Therap | 1978 |
Natriuresis-induced protection in acute myohemoglobinuric renal failure without renal cortical renin content depletion in the rat.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Chlorides; Disease Models, Animal; Female; Glycer | 1978 |
Elevation of rat erythrocyte nucleotide levels following acute renal failure induced by glycerol or mercuric chloride.
Topics: Acute Kidney Injury; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals | 1978 |
Scanning and transmission electron microscopy of mercuric chloride-induced acute tubular necrosis in rat kidney.
Topics: Acute Kidney Injury; Animals; Basement Membrane; Chlorides; Dose-Response Relationship, Drug; Endopl | 1975 |
Normal renocortical blood flow in experimental acute renal failure.
Topics: Acute Kidney Injury; Animals; Chlorides; Disease Models, Animal; Female; Glomerular Filtration Rate; | 1977 |
Acute renal failure caused by nephrotoxins.
Topics: Acute Kidney Injury; Animals; Body Water; Chlorides; Dehydration; Dogs; Glomerular Filtration Rate; | 1976 |
[Pre-renal failure due to villous adenoma of the colon].
Topics: Acute Kidney Injury; Adenoma; Aged; Aldosterone; Chlorides; Colonic Neoplasms; Creatinine; Humans; M | 1975 |
Surgery of the aged Management of renal, urinary, and genital problems.
Topics: Abdomen; Acute Kidney Injury; Age Factors; Aged; Chlorides; Female; Humans; Hypertension, Renal; Kid | 1975 |
Effects of furosemide on low-dose mercuric chloride acute renal failure in the rat.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Chlorides; Creatinine; Dose-Response Relationship | 1975 |
Opposite effects of diabetes on nephrotoxic and ischemic acute tubular necrosis.
Topics: Acute Kidney Injury; Animals; Chlorides; Chromium; Chromium Compounds; Diabetes Mellitus, Experiment | 1990 |
Hypochloraemic alkalosis after high-flux continuous haemofiltration and continuous arteriovenous haemofiltration with dialysis.
Topics: Acute Kidney Injury; Adult; Aged; Alkalosis; Chlorides; Female; Hemofiltration; Humans; Lactates; Ma | 1988 |
Nutrition in the management of renal failure in black children.
Topics: Acute Kidney Injury; Black or African American; Calcium; Chlorides; Humans; Infant; Liver Function T | 1987 |
A quantitative method of evaluating the diuretic response to furosemide in rats.
Topics: Acute Kidney Injury; Animals; Chlorides; Diuretics; Dopamine; Furosemide; Male; Potassium; Rats; Rat | 1988 |
Study on urinary chloride concentrations in acute renal failure.
Topics: Acute Kidney Injury; Adult; Chlorides; Female; Humans; Kidney Tubular Necrosis, Acute; Male; Middle | 1988 |
Ileal conduit.
Topics: Acute Kidney Injury; Alkalies; Chlorides; Colon; Female; Humans; Ileostomy; Male; Methods; Palliativ | 1967 |
[Preparation and therapeutic use of platelet concentrates].
Topics: Acids; Acute Kidney Injury; Blood Platelets; Blood Preservation; Blood Transfusion; Chlorides; Citra | 1969 |
Lecithin-cholesterol acyltransferase activity in diabetes mellitus and the effect of insulin on these cases.
Topics: Acidosis; Acute Kidney Injury; Acyltransferases; Adult; Aged; Bicarbonates; Carbon Radioisotopes; Ch | 1974 |
The treatment of lactic acidosis in the diabetic patient by peritoneal dialysis using sodium acetate. A report of two cases.
Topics: Acetates; Acute Kidney Injury; Aged; Bicarbonates; Blood Glucose; Carbon Dioxide; Chlorides; Diabeti | 1974 |
[Cytochrome oxidase isoenzymes of the kidneys and blood serum normally and in renal insufficiency].
Topics: Acute Kidney Injury; Agar; Animals; Chlorides; Electron Transport Complex IV; Electrophoresis; Gels; | 1973 |
Effect of renin immunization on mercuric chloride and glycerol-induced renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Antigens; Blood Pressure; Blood Urea Nitrogen; Chlorid | 1972 |
Shift toward anaerobic glycolysis in the regenerating rat kidney.
Topics: Acute Kidney Injury; Animals; Blood Glucose; Chlorides; Culture Techniques; Enzyme Induction; Glucos | 1970 |
Acute mercuric chloride nephrotoxicity. An electron microscopic and metabolic study.
Topics: Acute Kidney Injury; Aminohippuric Acids; Animals; Calcium; Cell Nucleus; Cell Survival; Chlorides; | 1974 |
Renal prostaglandin E during acute renal failure.
Topics: Acute Kidney Injury; Animals; Chlorides; Glycerol; Kidney; Male; Mercury; Prostaglandins; Rabbits; T | 1974 |
The influence of DL-A histocompatibility on the function and pathohistological changes in unmodified canine renal allografts.
Topics: Acute Kidney Injury; Animals; Antigen-Antibody Reactions; Arteritis; Bicarbonates; Blood Urea Nitrog | 1972 |
The use of parenteral alimentation in renal failure: the effect of an intravenous fat emulsion and essential amino acids on dogs undergoing bilateral nephrectomy.
Topics: Acute Kidney Injury; Amino Acids; Animals; Blood Urea Nitrogen; Chlorides; Creatinine; Dogs; Emulsio | 1972 |
Peritoneal dialysis solutions.
Topics: Acetates; Acute Kidney Injury; Blood Urea Nitrogen; Calcium; Chlorides; Coma; Glucose; Humans; Hyper | 1973 |
Prevention of dialysis disequilibrium syndrome by use of high sodium concentration in the dialysate.
Topics: Acute Kidney Injury; Adolescent; Adult; Blood Pressure; Body Weight; Chlorides; Electroencephalograp | 1973 |
An evaluation of isotopic calcium absorption tests.
Topics: Absorption; Acute Kidney Injury; Administration, Oral; Animals; Calcium; Calcium Radioisotopes; Catt | 1973 |
Antileukaemic and nephrotoxic properties of platinum compounds.
Topics: Acute Kidney Injury; Amines; Animals; Antineoplastic Agents; Chlorides; Epithelial Cells; Female; Ha | 1971 |
The use of mannitol to reduce the nephrotoxicity of amphotericin B.
Topics: Acute Kidney Injury; Amphotericin B; Animals; Blood Urea Nitrogen; Chlorides; Creatinine; Dogs; Kidn | 1972 |
[Secretion of gastric juice during hemodialysis].
Topics: Acute Kidney Injury; Adult; Ammonia; Calcium; Chlorides; Creatinine; Electrolytes; Female; Gastric A | 1971 |
[Effectiveness and limits of gastric dialysis].
Topics: Acute Kidney Injury; Adult; Blood Urea Nitrogen; Child; Chlorides; Humans; Intestinal Obstruction; M | 1971 |
Maintenance of renal function in salt loaded rats despite severe tubular necrosis induced by HgCl 2 .
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Chlorides; Drinking; Female; Inulin; Kidney; Kidn | 1971 |
[Intra- and extracellular electrolyte changes in acute kidney failure of the rat].
Topics: Acute Kidney Injury; Animals; Anuria; Biopsy; Blood Urea Nitrogen; Chlorides; Disease Models, Animal | 1969 |
Mercuric chloride-induced renal failure and intrarenal distribution of blood flow.
Topics: Acute Kidney Injury; Aminohippuric Acids; Animals; Blood Volume; Chlorides; Creatinine; Dogs; Glomer | 1969 |
The influence of uremia upon renal hypertension.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Chlorides; Hypertension, Renal; Kidney Tubules; Mercur | 1970 |
Studies on renal function in burns. II. Early signs of impaired renal function in lethal burns.
Topics: Acute Kidney Injury; Adult; Aged; Bicarbonates; Blood Proteins; Burns; Chlorides; Creatinine; Female | 1970 |
[Villous rectal adenoma with electrolyte imbalance].
Topics: Acute Kidney Injury; Adenoma; Blood Urea Nitrogen; Calcium; Chlorides; Humans; Hyponatremia; Male; M | 1970 |
[Symposium on homeostasis in disease states. 4. Serum electrolytes].
Topics: Acute Kidney Injury; Aged; Animals; Calcium; Chlorides; Dogs; Electrolytes; Female; Homeostasis; Hum | 1970 |
[Effect of thyroxine on the course of acute renal failure. II. Effect of L-thyroxine administration on plasma level and kidney excretion of various substances in rabbits presenting acute kidney failure (studies using the so-called sublimate nephrosis mode
Topics: Acute Kidney Injury; Animals; Blood Glucose; Blood Proteins; Calcium; Chlorides; Cholesterol; Creati | 1971 |
Fluid and electrolyte complications of peritoneal dialysis. Choice of dialysis solutions.
Topics: Acute Kidney Injury; Adult; Alkalosis; Bicarbonates; Blood; Blood Glucose; Blood Pressure; Blood Ure | 1971 |
Body water and electrolyte composition in acute renal failure.
Topics: Acute Kidney Injury; Adult; Aged; Bicarbonates; Chlorides; Extracellular Space; Humans; Middle Aged; | 1971 |
Cobalt excretion test for the assessment of body iron stores.
Topics: Acute Kidney Injury; Anemia, Hypochromic; Blood Urea Nitrogen; Bone Marrow; Chlorides; Cobalt; Cobal | 1971 |
[Advantages and special indications of limited peritoneal dialysis versus limited hemodialysis].
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Aged; Child; Child, Preschool; Chlorides; Glucose; Human | 1967 |
[8a. Consciousness disorders in acute renal insufficiency following surgery and injury].
Topics: Acute Kidney Injury; Chlorides; Gastrointestinal Diseases; Humans; Intracranial Pressure; Postoperat | 1967 |
[On the histochemistry of the renal medulla].
Topics: Acute Kidney Injury; Animals; Anuria; Aortic Valve Stenosis; Chlorides; Cyanides; Histocytochemistry | 1967 |
[Electrolyte and neuroendocrine equilibrium in acute kidney failure].
Topics: 17-Hydroxycorticosteroids; Acute Kidney Injury; Adult; Chlorides; Chlorpromazine; Erythrocytes; Fema | 1967 |
[Water-electrolytic and protein disorders in a case of villous hypersecreting tumor of the rectum].
Topics: Acid Phosphatase; Acute Kidney Injury; Animals; Bicarbonates; Cellulose; Chlorides; Chromatography, | 1967 |
Aldosterone secretion and sodium balance in salt-losing nephropathy.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Aldosterone; Anemia; Calcium; Chlorides; Dehydration; Die | 1968 |
A study by micropuncture and microdissection of acute renal damage in rats.
Topics: Acute Kidney Injury; Aminohippuric Acids; Animals; Carbon Isotopes; Chlorides; Chromates; Chronic Di | 1968 |
Hypercalcemia during the diuretic phase of acute renal failure.
Topics: Acute Kidney Injury; Adult; Blood Urea Nitrogen; Calcium; Chlorides; Diuresis; Humans; Hypercalcemia | 1968 |
Renal tubular lesions caused by mercuric chloride. Electron microscopic observations: degeneration of the pars recta.
Topics: Acute Kidney Injury; Animals; Chlorides; Endoplasmic Reticulum; Injections, Subcutaneous; Kidney Tub | 1968 |
[Acute renal failure caused by zinc chloride poisoning].
Topics: Acute Kidney Injury; Adult; Anuria; Chlorides; Humans; Male; Renal Dialysis; Shock, Septic; Suicide; | 1968 |
[On a method of using the artificial kidney in renal insufficiency].
Topics: Acetates; Acute Kidney Injury; Adult; Anesthesia, Local; Anuria; Calcium Chloride; Chlorides; Female | 1968 |
Pathogenesis of mercuric chloride-induced renal failure in the dog.
Topics: Acute Kidney Injury; Animals; Anuria; Chlorides; Dogs; Female; Glomerular Filtration Rate; Kidney Co | 1968 |
Low-cost system of peritoneal dialysis.
Topics: Acetates; Acute Kidney Injury; Calcium; Chemistry, Pharmaceutical; Chlorides; Costs and Cost Analysi | 1968 |
The effects of repeated administration of mercuric chloride on exfoliation of renal tubular cells and urinary glutamic-oxaloacetic transaminase activity in the rat.
Topics: Acute Kidney Injury; Animals; Aspartate Aminotransferases; Chlorides; Kidney Cortex Necrosis; Kidney | 1969 |
Intrarenal circulation in mercuric chloride-induced renal failure.
Topics: Acute Kidney Injury; Animals; Chlorides; Dogs; Female; Kidney; Male; Mercury; Methods; Radioisotopes | 1969 |
Phenolic acids in experimental uremia. I. Potential role of phenolic acids in the neurological manifestations of uremia.
Topics: Acute Kidney Injury; Animals; Behavior; Bicarbonates; Blood Urea Nitrogen; Calcium; Central Nervous | 1969 |