chlorine has been researched along with Acute Brain Injuries in 38 studies
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.
| Excerpt | Relevance | Reference |
|---|---|---|
| " after they had been assigned to one of 8 groups in a 3-way analysis of variance design that involved (1) induction of limbic seizures by a systemic injection of lithium/pilocarpine, (2) physical restraint, and (3) administration of acepromazine." | 7.68 | Extreme hypothermia induced by a synergism of acute limbic seizures, physical restraint, and acepromazine: implications for survival following brain injury. ( Bureau, YR; Persinger, MA, 1993) |
| "Phenytoin treatment prevented the occurrence of convulsive and EEG seizures; however, lipid peroxidation was unaffected (16." | 5.27 | Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy. ( Triggs, WJ; Willmore, LJ, 1984) |
| " after they had been assigned to one of 8 groups in a 3-way analysis of variance design that involved (1) induction of limbic seizures by a systemic injection of lithium/pilocarpine, (2) physical restraint, and (3) administration of acepromazine." | 3.68 | Extreme hypothermia induced by a synergism of acute limbic seizures, physical restraint, and acepromazine: implications for survival following brain injury. ( Bureau, YR; Persinger, MA, 1993) |
| "Amiodarone (AMD) is a powerful antiarrhythmic drug preferred for treatments of tachycardias." | 1.91 | Oxidative Brain Injury Induced by Amiodarone in Rats: Protective Effect of S-methyl Methionine Sulfonium Chloride. ( Turkyilmaz, IB, 2023) |
| "Female LCR rats had less iron-induced brain swelling, smaller lesion volumes, and reduced BBB disruption and HO-1 upregulation compared with male LCR rats." | 1.43 | Effect of Gender on Iron-induced Brain Injury in Low Aerobic Capacity Rats. ( Britton, SL; Du, H; Gao, F; Hua, Y; Keep, RF; Koch, LG; Xi, G; Zheng, M, 2016) |
| "Phenytoin treatment prevented the occurrence of convulsive and EEG seizures; however, lipid peroxidation was unaffected (16." | 1.27 | Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy. ( Triggs, WJ; Willmore, LJ, 1984) |
| "Most studies of clinically relevant cerebral edema emphasize the effect of added tissue fluid in white matter on gross distortion with transtentorial and subfalcine brain herniation." | 1.26 | Biology of glial swelling in experimental brain edema. ( Auen, EL; Barron, KD; Bourke, RS; Kimelberg, HK; Nelson, LR; Popp, AJ; Waldman, JB, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (52.63) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 8 (21.05) | 29.6817 |
| 2010's | 6 (15.79) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Igarashi, K | 1 |
| Iwai, H | 1 |
| Tanaka, KI | 1 |
| Kuwahara, Y | 1 |
| Kitanaka, J | 1 |
| Kitanaka, N | 1 |
| Kurimasa, A | 1 |
| Tomita, K | 1 |
| Sato, T | 1 |
| Turkyilmaz, IB | 1 |
| Ichai, C | 1 |
| Payen, JF | 1 |
| Orban, JC | 1 |
| Quintard, H | 1 |
| Roth, H | 1 |
| Legrand, R | 1 |
| Francony, G | 1 |
| Leverve, XM | 1 |
| Zhao, F | 1 |
| Xi, G | 2 |
| Liu, W | 1 |
| Keep, RF | 2 |
| Hua, Y | 2 |
| Zheng, M | 1 |
| Du, H | 1 |
| Gao, F | 1 |
| Koch, LG | 1 |
| Britton, SL | 1 |
| Martínez-Valverde, T | 1 |
| Sánchez-Guerrero, A | 1 |
| Vidal-Jorge, M | 1 |
| Torné, R | 1 |
| Castro, L | 1 |
| Gandara, D | 1 |
| Munar, F | 2 |
| Poca, MA | 2 |
| Sahuquillo, J | 2 |
| Shulga, A | 1 |
| Thomas-Crusells, J | 1 |
| Sigl, T | 1 |
| Blaesse, A | 1 |
| Mestres, P | 1 |
| Meyer, M | 1 |
| Yan, Q | 1 |
| Kaila, K | 1 |
| Saarma, M | 1 |
| Rivera, C | 1 |
| Giehl, KM | 1 |
| Zhu, L | 1 |
| Wang, HD | 1 |
| Yu, XG | 1 |
| Jin, W | 1 |
| Qiao, L | 1 |
| Lu, TJ | 1 |
| Hu, ZL | 1 |
| Zhou, J | 1 |
| Bourdeaux, C | 1 |
| Brown, J | 1 |
| Gibson, CJ | 1 |
| Meyer, RC | 1 |
| Hamm, RJ | 1 |
| Limbrick, DD | 1 |
| Sombati, S | 1 |
| DeLorenzo, RJ | 1 |
| Makara, JK | 1 |
| Rappert, A | 1 |
| Matthias, K | 1 |
| Steinhäuser, C | 1 |
| Spät, A | 1 |
| Kettenmann, H | 1 |
| COOPER, IS | 1 |
| THOMSEN, AC | 2 |
| ANTHONISEN, P | 1 |
| HILDEN, T | 1 |
| FAGIN, ID | 1 |
| MEHAN, DJ | 1 |
| GASS, HH | 1 |
| CLASEN, RA | 3 |
| COOKE, PM | 1 |
| PANDOLFI, S | 2 |
| CARNECKI, G | 1 |
| BRYAR, G | 1 |
| Yao, Y | 1 |
| Sun, S | 1 |
| Kong, Q | 1 |
| Tong, E | 1 |
| Eisenhut, M | 1 |
| Bonislawski, DP | 1 |
| Schwarzbach, EP | 1 |
| Cohen, AS | 1 |
| Yap, SL | 1 |
| Spector, RG | 1 |
| Willmore, LJ | 2 |
| Rubin, JJ | 1 |
| Triggs, WJ | 1 |
| Bourke, RS | 1 |
| Kimelberg, HK | 2 |
| Nelson, LR | 1 |
| Barron, KD | 2 |
| Auen, EL | 1 |
| Popp, AJ | 1 |
| Waldman, JB | 1 |
| Bureau, YR | 1 |
| Persinger, MA | 1 |
| Hasbani, MJ | 1 |
| Hyrc, KL | 1 |
| Faddis, BT | 1 |
| Romano, C | 1 |
| Goldberg, MP | 1 |
| Ferrer, AM | 1 |
| de Nadal, M | 1 |
| Pedraza, S | 1 |
| Garnacho, A | 1 |
| Rose, JW | 1 |
| Waniewski, RA | 1 |
| Cragoe, EJ | 1 |
| Casey, D | 1 |
| Kvitnitskii-Ryzhov, IuN | 1 |
| Hindo, WA | 1 |
| Rayudu, GV | 1 |
| Ermakova, IA | 1 |
| Burdine, JA | 1 |
| Waltz, TA | 1 |
| Matsen, FA | 1 |
| Rapp, F | 1 |
| Reddy, DR | 1 |
| Prabhakar, V | 1 |
| Rao, BD | 1 |
| Kolb, R | 1 |
| Steinbereithner, K | 1 |
| Mineta, T | 1 |
| Tsutsumi, E | 1 |
| Suzuki, H | 1 |
| Kasai, M | 1 |
| Metzel, E | 1 |
| Zimmermann, WE | 1 |
| Watanabe, T | 1 |
| Fujita, Y | 1 |
| Mitani, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Coagulation Activation in Patients With Intracranial Hypertension After Treatment With Mannitol or Hypertonic Saline Solution.[NCT03409237] | 0 participants (Actual) | Observational | 2020-12-03 | Withdrawn (stopped due to No participant enrolled. The human resources to perform the study also due to the COBID emegency) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for chlorine and Acute Brain Injuries
| Article | Year |
|---|---|
Half-molar sodium lactate infusion to prevent intracranial hypertensive episodes in severe traumatic brain injured patients: a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Body Fluids; Brain Injuries; Chlorides; Double-Blind Method; Female; Humans | 2013 |
Cerebral hemodynamic effects of 7.2% hypertonic saline in patients with head injury and raised intracranial pressure.
Topics: Adult; Aged; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Chlorides; Female; Hemodyn | 2000 |
36 other studies available for chlorine and Acute Brain Injuries
| Article | Year |
|---|---|
Neuroprotective effect of oxytocin on cognitive dysfunction, DNA damage, and intracellular chloride disturbance in young mice after cranial irradiation.
Topics: Animals; Brain Injuries; Chlorides; Cognitive Dysfunction; Cranial Irradiation; DNA Damage; Hippocam | 2022 |
Oxidative Brain Injury Induced by Amiodarone in Rats: Protective Effect of S-methyl Methionine Sulfonium Chloride.
Topics: Amiodarone; Animals; Antioxidants; Brain; Brain Injuries; Chlorides; Glutathione; Oxidative Stress; | 2023 |
Minocycline Attenuates Iron-Induced Brain Injury.
Topics: Albumins; Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Blotting, Western; Brain; Brain Edema | 2016 |
Effect of Gender on Iron-induced Brain Injury in Low Aerobic Capacity Rats.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain Edema; Brain Injuries; Caudate Nucleus; Chlor | 2016 |
Characterization of the Ionic Profile of the Extracellular Space of the Injured and Ischemic Brain: A Microdialysis Study.
Topics: Adolescent; Adult; Brain Injuries; Brain Ischemia; Chlorides; Extracellular Space; Female; Humans; I | 2017 |
Posttraumatic GABA(A)-mediated [Ca2+]i increase is essential for the induction of brain-derived neurotrophic factor-dependent survival of mature central neurons.
Topics: Animals; Animals, Newborn; Axons; Axotomy; Brain Injuries; Brain-Derived Neurotrophic Factor; Bumeta | 2008 |
Erythropoietin prevents zinc accumulation and neuronal death after traumatic brain injury in rat hippocampus: in vitro and in vivo studies.
Topics: Analysis of Variance; Animals; Brain Injuries; Cell Count; Cell Death; Cells, Cultured; Chlorides; D | 2009 |
Sodium bicarbonate lowers intracranial pressure after traumatic brain injury.
Topics: Blood Pressure; Brain Injuries; Catheterization, Central Venous; Cerebrovascular Circulation; Chlori | 2010 |
Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus.
Topics: Animals; Blotting, Western; Brain Injuries; Calcium Channel Blockers; Calcium Signaling; Chlorides; | 2010 |
Calcium influx constitutes the ionic basis for the maintenance of glutamate-induced extended neuronal depolarization associated with hippocampal neuronal death.
Topics: Animals; Animals, Newborn; Brain Injuries; Calcium; Calcium Channel Blockers; Calcium Signaling; Cel | 2003 |
Astrocytes from mouse brain slices express ClC-2-mediated Cl- currents regulated during development and after injury.
Topics: Animals; Astrocytes; Brain; Brain Injuries; Cadmium; Cell Membrane; Cerebral Cortex; Cesium; Chlorid | 2003 |
Disorders of electrolyte metabolism in diseases of the central nervous system.
Topics: Brain; Brain Injuries; Brain Neoplasms; Central Nervous System; Chlorides; Electrolytes; Humans; Sod | 1953 |
[Hyperchloremia and hypernatremia after cranial trauma].
Topics: Blood; Brain; Brain Injuries; Chlorides; Humans; Hypernatremia; Sodium; Water-Electrolyte Imbalance | 1954 |
Electrolyte disturbances in cerebral lesions.
Topics: Blood; Brain; Brain Injuries; Chlorides; Sodium; Sodium, Dietary; Water-Electrolyte Imbalance; Wound | 1954 |
Hyponatremia and hypochloremia as a complication of head injury; report of a case simulating intracranial hematoma.
Topics: Brain; Brain Injuries; Cerebral Hemorrhage; Chlorides; Craniocerebral Trauma; Diagnosis, Differentia | 1958 |
HYPERTONIC UREA IN EXPERIMENTAL CEREBRAL EDEMA.
Topics: Animals; Blood Chemical Analysis; Brain Edema; Brain Injuries; Calcium; Cerebral Hemorrhage; Chlorid | 1965 |
7beta-hydroxycholesterol reduces the extent of reactive gliosis caused by iron deposition in the hippocampus but does not attenuate the iron-induced seizures in rats.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents; Astrocytes; Brain Injuries; Chlorides; Convuls | 2006 |
Re: "Circulating levels of KL-6 in acute respiratory distress syndrome sepsis or traumatic brain injury in critically ill children" by Briassoulis et al. (Pediatr Pulmonol 2006; 41:790-795).
Topics: Adrenergic beta-Agonists; Brain Injuries; Chloride Channels; Chlorides; Cyclic AMP; Cystic Fibrosis | 2006 |
Brain injury impairs dentate gyrus inhibitory efficacy.
Topics: Animals; Blotting, Western; Brain Injuries; Chlorides; Dentate Gyrus; Electrophysiology; Fluorescent | 2007 |
Cerebral composition and function in experimental brain injury in the rat.
Topics: Animals; Autoradiography; Biological Transport, Active; Brain Chemistry; Brain Edema; Brain Injuries | 1967 |
Effects of antiperoxidants on FeCl2-induced lipid peroxidation and focal edema in rat brain.
Topics: Animals; Brain Edema; Brain Injuries; Cerebral Cortex; Chlorides; Ferric Compounds; Iron; Lipid Pero | 1984 |
Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy.
Topics: Animals; Brain Injuries; Chlorides; Electroencephalography; Epilepsy; Ferric Compounds; Lipid Peroxi | 1984 |
Biology of glial swelling in experimental brain edema.
Topics: Animals; Astrocytes; Brain Edema; Brain Injuries; Capillaries; Cats; Cerebral Cortex; Chlorides; Neu | 1980 |
Extreme hypothermia induced by a synergism of acute limbic seizures, physical restraint, and acepromazine: implications for survival following brain injury.
Topics: Acepromazine; Animals; Body Temperature Regulation; Brain Injuries; Chlorides; Hypothermia; Limbic S | 1993 |
Distinct roles for sodium, chloride, and calcium in excitotoxic dendritic injury and recovery.
Topics: Animals; Brain Injuries; Bridged Bicyclo Compounds; Calcium; Cells, Cultured; Chlorides; Coculture T | 1998 |
Astrocytic swelling in traumatic-hypoxic brain injury. Beneficial effects of an inhibitor of anion exchange transport and glutamate uptake in glial cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Astrocytes; Biological Transpor | 1989 |
Reserpine in experimental cerebral edema: further observations.
Topics: Animals; Blood Pressure; Body Temperature; Brain Edema; Brain Injuries; Cerebral Cortex; Cerebral He | 1974 |
[The pathogenesis of edema and swelling of the brain].
Topics: Astrocytes; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Capillary Permeability; Carbon | 1974 |
Technetium in cryogenic cerebral injury and edema.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Brain Neoplasms; Cerebrospinal Fluid Proteins; Cerebrov | 1972 |
[Osmotic shifts in the blood and cerebrospinal fluid of the newborn following asphyxia and intrauterine trauma].
Topics: Acid-Base Equilibrium; Asphyxia Neonatorum; Birth Injuries; Blood; Blood Glucose; Brain Injuries; Ca | 1973 |
Localization of 113mIn-chelates compared with 99mTc-sodium pertechnetate in experimental cerebral lesions.
Topics: Animals; Blood-Brain Barrier; Brain Injuries; Brain Neoplasms; Cerebral Cortex; Chlorides; Cricetina | 1969 |
Tube feeding syndrome (protein intoxication), (a report of three cases).
Topics: Adult; Aged; Brain Injuries; Chlorides; Dehydration; Dietary Proteins; Enteral Nutrition; Humans; Hy | 1971 |
[Comparative studies on the behaviour of CSF- and serum osmolarity under high osmotic load in head and brain injuries].
Topics: Acid-Base Equilibrium; Adolescent; Adult; Amino Acids; Brain Injuries; Cerebrospinal Fluid; Child; C | 1972 |
Clinical and experimental studies on cerebral hypernatremia.
Topics: Adult; Bone and Bones; Brain; Brain Injuries; Brain Neoplasms; Chlorides; Craniocerebral Trauma; Ele | 1971 |
Changes of oxygen pressure, acid-base balance, metabolites and electrolytes in cerebrospinal fluid and blood after cerebral injury.
Topics: Acid-Base Equilibrium; Bicarbonates; Brain; Brain Edema; Brain Injuries; Carbon Dioxide; Chlorides; | 1971 |
[Metabolic alkalosis during convalescence of from head injuries].
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Adult; Alkalosis; Blood Gas Analysis; Brain Injuries; | 1968 |