Page last updated: 2024-10-24

chlordiazepoxide and Substance Withdrawal Syndrome

chlordiazepoxide has been researched along with Substance Withdrawal Syndrome in 164 studies

Chlordiazepoxide: An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
chlordiazepoxide : A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.

Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.

Research Excerpts

ExcerptRelevanceReference
"Forty patients with primary chronic alcoholism took part in a randomized, double-blind, comparative group study of clobazam and chlordiazepoxide in the treatment of acute alcohol withdrawal."9.05A comparison of the efficacy and tolerability of clobazam and chlordiazepoxide in the treatment of acute withdrawal from alcohol in patients with primary alcoholism. ( Mukherjee, PK, 1983)
"A 27-year-old, Caucasian female with ethanol dependence who had objective symptoms of withdrawal experienced worsening of her delirium after administration of chlordiazepoxide, but improved with lorazepam and cleared with discontinuation of benzodiazepine administration."8.12Chlordiazepoxide-induced delirium in a patient undergoing alcohol withdrawal: a case report. ( Arabadjief, MA; Bashir, S; Bergman, CL; El-Mallakh, RS; Elsayed, OH; Gundumalla, MR; Menefee, DS; Moulana, NZ, 2022)
") were determined on anxiety induced in female NMRI mice by withdrawal from 21 days of chronic administration of chlordiazepoxide."7.71The new antiepileptic drug levetiracetam normalises chlordiazepoxide withdrawal-induced anxiety in mice. ( Gower, AJ; Klitgaard, H; Lamberty, Y, 2002)
"The authors report a case of a 55-year-old man undergoing a triazolam withdrawal syndrome that was recognized and treated with high doses of benzodiazepines, but the patient nevertheless developed seizures."7.67Seizures following triazolam withdrawal despite benzodiazepine treatment. ( Pawluczyk, S; Schneider, LS; Syapin, PJ, 1987)
"The pattern of cardiac arrhythmias and their treatment, by propranolol and chlordiazepoxide, during the first 48 hr of alcohol withdrawal has been studied."7.66Propranolol and chlordiazepoxide effects on cardiac arrhythmias during alcohol withdrawal. ( Jacob, MS; MacLeod, SM; Sellers, EM; Ti, TY; Zilm, DH, 1980)
"Intraperitoneal injection of ethanol (1-2 g/kg) and chlordiazepoxide (2-16 mg/kg) suppressed susceptibility to audiogenically induced, clonic-tonic seizures and antagonized forelimb tremor in rats undergoing ethanol withdrawal, 30 min after treatment."7.66Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. ( Breese, GR; Frye, GD; McCown, TJ, 1983)
"Forty patients with primary chronic alcoholism took part in a randomized, double-blind, comparative group study of clobazam and chlordiazepoxide in the treatment of acute alcohol withdrawal."5.05A comparison of the efficacy and tolerability of clobazam and chlordiazepoxide in the treatment of acute withdrawal from alcohol in patients with primary alcoholism. ( Mukherjee, PK, 1983)
"A 27-year-old, Caucasian female with ethanol dependence who had objective symptoms of withdrawal experienced worsening of her delirium after administration of chlordiazepoxide, but improved with lorazepam and cleared with discontinuation of benzodiazepine administration."4.12Chlordiazepoxide-induced delirium in a patient undergoing alcohol withdrawal: a case report. ( Arabadjief, MA; Bashir, S; Bergman, CL; El-Mallakh, RS; Elsayed, OH; Gundumalla, MR; Menefee, DS; Moulana, NZ, 2022)
") were determined on anxiety induced in female NMRI mice by withdrawal from 21 days of chronic administration of chlordiazepoxide."3.71The new antiepileptic drug levetiracetam normalises chlordiazepoxide withdrawal-induced anxiety in mice. ( Gower, AJ; Klitgaard, H; Lamberty, Y, 2002)
"6 mg/kg pentylenetetrazole and exhibited an increase in susceptibility to clonic seizures."3.68State-dependent stimulus control: cueing attributes of ethanol "hangover" in rats. ( Gauvin, DV; Goulden, KL; Holloway, FA, 1993)
"Abrupt withdrawal of the centrally-acting antihypertensive agent, clonidine, is associated with a high incidence of rebound hypertension and tachycardia, with symptoms of sympathetic overactivity and increased catecholamine excretion."3.67Regimen for the control of blood pressure and symptoms during clonidine withdrawal. ( Campbell, BC; Reid, JL, 1985)
"The authors report a case of a 55-year-old man undergoing a triazolam withdrawal syndrome that was recognized and treated with high doses of benzodiazepines, but the patient nevertheless developed seizures."3.67Seizures following triazolam withdrawal despite benzodiazepine treatment. ( Pawluczyk, S; Schneider, LS; Syapin, PJ, 1987)
"Rats were tested in the elevated plus-maze test of anxiety after a probe injection of chlordiazepoxide (CDP 5 mg/kg) following short-term (5 days) or long-term (20 days) pretreatment with 5 or 20 mg/kg/day."3.67Anxiogenic effects in benzodiazepine withdrawal are linked to the development of tolerance. ( Aranko, K; Baldwin, HA; File, SE, 1987)
"Intraperitoneal injection of ethanol (1-2 g/kg) and chlordiazepoxide (2-16 mg/kg) suppressed susceptibility to audiogenically induced, clonic-tonic seizures and antagonized forelimb tremor in rats undergoing ethanol withdrawal, 30 min after treatment."3.66Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. ( Breese, GR; Frye, GD; McCown, TJ, 1983)
"The pattern of cardiac arrhythmias and their treatment, by propranolol and chlordiazepoxide, during the first 48 hr of alcohol withdrawal has been studied."3.66Propranolol and chlordiazepoxide effects on cardiac arrhythmias during alcohol withdrawal. ( Jacob, MS; MacLeod, SM; Sellers, EM; Ti, TY; Zilm, DH, 1980)
"Lorazepam was used as rescue medication."2.82A randomized, open-label, standard controlled, parallel group study of efficacy and safety of baclofen, and chlordiazepoxide in uncomplicated alcohol withdrawal syndrome. ( Girish, K; Manjunatha, R; Nagraj, M; Pandit, LV; Pundarikaksha, HP; Shruthi, R; Vasundara, K; Vijendra, R; Vikram Reddy, K, 2016)
"Lorazepam treated group showed a significant difference in the rate of improvement over 48 h compared to chlordiazepoxide group (70."2.78A double blind randomised comparison of chlordiazepoxide and lorazepam in alcohol withdrawal. ( Mohandas, E; Rajmohan, V; Sushil, K, 2013)
"Phenobarbital and LZ were similarly effective in the treatment of mild/moderate alcohol withdrawal in the ED and at 48 hours."2.76A prospective, randomized, trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal. ( Barnes, RL; Dery, RA; Hendey, GW; Mentler, P; Snowden, B, 2011)
"One hundred consecutive consenting male inpatients in a state of moderately severe, uncomplicated alcohol withdrawal at screening were randomized to receive either lorazepam (8 mg/day) or chlordiazepoxide (80 mg/day) with dosing down-titrated to zero in a fixed-dose schedule across 8 treatment days."2.74A randomized, double-blind comparison of lorazepam and chlordiazepoxide in patients with uncomplicated alcohol withdrawal. ( Andrade, C; Kumar, CN; Murthy, P, 2009)
"Chlordiazepoxide was administered to only 41 patients (38%), yet 92 (85%) of the 108 enrolled successfully completed outpatient detoxification without medical complications."2.69Individualized treatment for outpatients withdrawing from alcohol. ( Briggs, MJ; Henderson, KL; Wiseman, EJ, 1998)
"While having significant withdrawal symptoms, 50 hospitalized men were randomly assigned to receive either transdermal clonidine or chlordiazepoxide over a 4-day study period."2.67Transdermal clonidine versus chlordiazepoxide in alcohol withdrawal: a randomized, controlled clinical trial. ( Baumgartner, GR; Rowen, RC, 1991)
" The two drugs were administered four times a day in double dummy conditions, according to a fixed-flexible decreasing dosage schedule (six days basic regimen)."2.66Double blind study on the efficacy and safety of tetrabamate and chlordiazepoxide in the treatment of the acute alcohol withdrawal syndrome. ( Chabot, F; Chawla, S; Forest, JC; Garcin, F; Guay, D; Huot, J; Marquis, PA; Martin, S; Radouco-Thomas, S; Stewart, G, 1989)
" A flexible dosage schedule was followed for 5 days with the objective of using the largest dose on the first day, followed by daily reductions as clinically feasible."2.66Halazepam in the management of acute alcohol withdrawal syndrome. ( Fine, EW; Mendels, J; Michals, TJ; Wasserman, TW, 1985)
"Clonidine was more effective than chlordiazepoxide at reducing alcohol withdrawal scale scores, systolic blood pressures, and heart rates over the entire study period."2.66Clonidine vs chlordiazepoxide in the management of acute alcohol withdrawal syndrome. ( Baumgartner, GR; Rowen, RC, 1987)
"Bromocriptine was ineffective in treating withdrawal symptoms, whilst chlormethiazole and chlordiazepoxide were equally effective."2.66Double-blind controlled trial of bromocriptine, chlordiazepoxide and chlormethiazole for alcohol withdrawal symptoms. ( Burroughs, AK; Morgan, MY; Sherlock, S, 1985)
"The chlordiazepoxide treatment produced suppression of rapid eye movement (REM) sleep lasting for about 4 days and virtually eliminated delta sleep (stages III and IV) during the recovery period."2.64Residual effects of ethanol and chlordiazepoxide treatments for alcohol withdrawal. ( Allen, RP; Funderburk, FR; Wagman, AM, 1978)
"Treatment with baclofen is easy to manage and rarely produces euphoria or other pleasant effects, or craving for the drug."2.55Baclofen for alcohol withdrawal. ( Liu, J; Wang, LN, 2017)
" Bases for selection include: (1) availability of other than oral dosage forms; (2) differences in additive effect with alcohol in producing central nervous system depression; (3) differences in anticonvulsant effect; and (4) differences in duration of effect in the body (ie, half-life)."2.36Selection among benzodiazepines for alcohol withdrawal. ( Keeler, MH; Miller, WC, 1977)
"However, withdrawal symptoms may occur in patients receiving recommended doses and/or short-term therapy."2.36Benzodiazepine withdrawal syndrome: a literature review and evaluation. ( MacKinnon, GL; Parker, WA, 1982)
"Severe AWS can develop into delirium tremens (DT), which is potentially life-threatening."1.51Lorazepam versus chlordiazepoxide for the treatment of alcohol withdrawal syndrome and prevention of delirium tremens in general medicine ward patients. ( Bergeron, JB; March, KL; Reaves, AB; Sakaan, SA; Self, TH; Slayton, MM; Twilla, JD, 2019)
"Phenobarbital treatment was associated with decreased mortality, which might be confounded by somatic comorbidity among patients receiving chlordiazepoxide."1.43Phenobarbital compared to benzodiazepines in alcohol withdrawal treatment: A register-based cohort study of subsequent benzodiazepine use, alcohol recidivism and mortality. ( Askgaard, G; Fink-Jensen, A; Hallas, J; Madsen, KG; Molander, AC; Pottegård, A, 2016)
" In order to investigate the relationship between tolerance and withdrawal to the cue properties of CDP, CDP dose-response curves were determined 24 h following treatment with SAL or 10 mg/kg CDP."1.33Evidence for PTZ-like cues as a function of time following treatment with chlordiazepoxide: implications for understanding tolerance and withdrawal. ( Barrett, RJ; Smith, RL, 2005)
"Alcohol withdrawal (especially delirium tremens) poses significant potential morbidity to postsurgical patients."1.29Trends in the management of alcohol withdrawal syndrome. ( Moore, M; Newman, JP; Terris, DJ, 1995)
" Three tests were used in which the benzodiazepine antagonist flumazenil was administered to rats receiving chronic administration of chlordiazepoxide."1.29Conflicting evidence regarding the efficacy of ondansetron in benzodiazepine withdrawal. ( Emmett-Oglesby, MW; Hooper, ML; Lal, H; Lane, JD; Lytle, DA; Prather, PL; Rezazadeh, SM; Rowan, GA, 1993)
" That bretazenil did not produce acute physical dependence supports the findings of others (20,23) who report that chronic administration of bretazenil does not result in physical dependence."1.29Chlordiazepoxide, but not bretazenil, produces acute dependence, as evidenced by disruptions in schedule-controlled behavior. ( Bronson, ME, 1994)
" Drug was most often given on a fixed dosing schedule with additional medication "as needed" (52% of the programs)."1.29Alcohol withdrawal: a nationwide survey of inpatient treatment practices. ( Friedman, LS; Mayo-Smith, MF; Saitz, R, 1995)
" Using a cumulative dosing procedure, PTZ substituted for PTZ, and MDZ, chlordiazepoxide and diazepam (DZP) substituted for MDZ, in a dose-dependent manner."1.28Tolerance, cross-tolerance and withdrawal in rats made dependent on diazepam. ( Boone, MS; Emmett-Oglesby, MW; Pugh, SL, 1992)
" These data support recent claims that GR38032F attenuates benzodiazepine withdrawal, and they indicate that this effect shows an inverted U-shaped dose-response curve."1.28Effects of the 5-HT3 antagonist GR38032F (ondansetron) on benzodiazepine withdrawal in rats. ( Goudie, AJ; Leathley, MJ, 1990)
"Pre-treatment with ondansetron (0."1.28Effects of 5-HT3 receptor antagonists on behavioural measures of naloxone-precipitated opioid withdrawal. ( Higgins, GA; Joharchi, N; Nguyen, P; Sellers, EM, 1991)
" Based on the "chronically equivalent" dosing principle, a regimen has been devised to maintain rats in a state of quantifiable intoxication for 5 weeks."1.27Experimental induction of benzodiazepine tolerance and physical dependence. ( Boisse, NR; Ryan, GP, 1983)
" Furthermore, chronic administration and withdrawal of 1,3-BD caused CNS hyperexcitability in rats that was characteristic of physical dependence."1.26Effects of acute and chronic 1,3-butanediol treatment on central nervous system function: a comparison with ethanol. ( Breese, GR; Chapin, RE; Frye, GD; Kilts, CD; Mailman, RB; Mueller, RA; Vogel, RA, 1981)
"Theories concerning schizophrenia and affective disease are shown to be based on the mode of action of drugs discovered in the 1950s and used in the treatment of these disorders."1.26Biology of psychoses: past research and new frontiers. ( Brodie, HK, 1977)
"Propranolol alone was more effective than either chlordiazepoxide or a combination of chlordiazepoxide and propranolol in alleviating the symptoms of the alcohol withdrawal syndrome."1.26Comparative efficacy of propranolol and chlordiazepoxide in alcohol withdrawal. ( Degani, NC; Sellers, EM; Zilm, DH, 1977)

Research

Studies (164)

TimeframeStudies, this research(%)All Research%
pre-1990115 (70.12)18.7374
1990's31 (18.90)18.2507
2000's6 (3.66)29.6817
2010's9 (5.49)24.3611
2020's3 (1.83)2.80

Authors

AuthorsStudies
Osler, M1
Jørgensen, MB1
Arabadjief, MA1
Elsayed, OH1
Bashir, S1
Gundumalla, MR1
Menefee, DS1
Bergman, CL1
Moulana, NZ1
El-Mallakh, RS1
Pedersen, SA1
Klesse, T1
Findal Andreasen, M1
Dalhoff, KP1
Andersen, CU1
Liu, J1
Wang, LN1
March, KL1
Twilla, JD1
Reaves, AB1
Self, TH1
Slayton, MM1
Bergeron, JB1
Sakaan, SA1
Rajmohan, V1
Sushil, K1
Mohandas, E1
Prakash, S1
Mandal, P1
Askgaard, G1
Hallas, J1
Fink-Jensen, A1
Molander, AC1
Madsen, KG1
Pottegård, A1
Girish, K1
Vikram Reddy, K1
Pandit, LV1
Pundarikaksha, HP1
Vijendra, R1
Vasundara, K1
Manjunatha, R1
Nagraj, M1
Shruthi, R1
Kumar, CN1
Andrade, C1
Murthy, P1
Rothwell, PE1
Thomas, MJ1
Gewirtz, JC2
Hendey, GW1
Dery, RA1
Barnes, RL1
Snowden, B1
Mentler, P1
Keys, VA1
Husain, OM1
Lynas, PS1
Totty, JP1
Williams, K1
Waring, WS1
Harris, AC1
HOLLISTER, LE2
MOTZENBECKER, FP1
DEGAN, RO1
KISSEN, MD2
KOUTSKY, CD1
SLETEN, IW1
SERENY, G1
KALANT, H1
Lelas, S1
Wong, H1
Li, YW1
Heman, KL1
Ward, KA1
Zeller, KL1
Sieracki, KK1
Polino, JL1
Godonis, HE1
Ren, SX1
Yan, XX1
Arneric, SP1
Robertson, DW1
Hartig, PR1
Grossman, S1
Trainor, GL1
Taub, RA1
Zaczek, R1
Gilligan, PJ1
McElroy, JF1
Barrett, RJ1
Smith, RL1
Ewing, JA1
Bakewell, WE1
Tucker, JF1
Plant, NT1
von Uexküll, A1
Collier, HO1
MacKinnon, GL1
Parker, WA1
Shader, RI3
Greenblatt, DJ4
Mukherjee, PK1
Frye, GD2
McCown, TJ1
Breese, GR3
Solomon, J1
Rouck, LA1
Koepke, HH1
Lepola, U1
Kokko, S1
Nuutila, J1
Gordin, A1
Ryan, GP2
Boisse, NR5
Guarino, JJ3
Jasinski, DR1
Haertzen, CA1
Henningfield, JE1
Johnson, RE1
Makhzoumi, HM1
Miyasato, K1
Lund, S1
Starklint, JF1
Vaag, UH1
Wang, AG1
Valdman, AV1
Zvartau, EE1
Zilm, DH3
Jacob, MS1
MacLeod, SM2
Sellers, EM6
Ti, TY1
Petursson, H1
Lader, MH1
Chapin, RE1
Vogel, RA1
Mailman, RB1
Kilts, CD1
Mueller, RA1
Chan, AW5
Leong, FW4
Schanley, DL4
Howe, SM1
Walters, L1
Nel, P1
Goudie, AJ4
Leathley, MJ4
Sala, M1
Leone, MP1
Lampugnani, P1
Braida, D1
Gori, E1
Newman, JP1
Terris, DJ1
Moore, M1
Sullivan, JT1
Emmett-Oglesby, MW6
Lytle, DA2
English, SA1
Saitz, R2
Mayo-Smith, MF2
Roberts, MS1
Redmond, HA1
Bernard, DR1
Calkins, DR1
Fuller, RK1
Gordis, E1
Bronson, ME1
Prather, PL2
Rezazadeh, SM2
Lane, JD1
Rowan, GA2
Hooper, ML1
Lal, H2
Harrison, AA1
Cannizzaro, G1
Flugy, A1
Cannizzaro, C1
Gagliano, M1
Sabatino, M1
Gauvin, DV1
Goulden, KL1
Holloway, FA1
Bird, RD1
Makela, EH1
Criswell, HE1
Friedman, LS1
Hyman, SE1
Thomas, H1
Mörchen, G1
Wiseman, EJ1
Henderson, KL1
Briggs, MJ1
Cao, BJ1
Rodgers, RJ1
Wooddell, WJ1
Lamberty, Y1
Gower, AJ1
Klitgaard, H1
Smith, RF1
Fialkov, MJ1
Hall, RC1
Kirkpatrick, B1
Baldino, F1
Cowan, A1
Geller, EB1
Adler, MW1
Edwards, G1
Zaluzny, SG1
Chesher, GB1
Jackson, DM1
Malor, R1
Funderburk, FR2
Allen, RP3
Wagman, AM3
Coleman, JH1
Evans, WE1
Kissin, B3
Menken, M1
Buonpane, N1
Perly, R1
Keeler, MH1
Miller, WC1
Brodie, HK1
Runion, HI1
Fowler, FN1
Pena-Ramos, A2
Hornberger, R1
Degani, NC1
Franke, K1
Giles, HG1
Degani, N1
Brown, WA1
Laughren, TP1
Williams, BW1
Robertson, CC1
Palestine, ML1
Alatorre, E1
Rothstein, E2
Cobble, JC1
Sampson, N1
Blum, K2
Eubanks, JD2
Wallace, JE2
Hamilton, H1
Schwertner, H1
Morgan, WW1
McGrath, SD1
Athinarayanan, P1
Pierog, SH1
Nigam, SK1
Glass, L1
Pugh, SL1
Boone, MS1
Dugovic, C1
Meert, TF1
Ashton, D1
Clincke, GH1
File, SE7
Zharkovsky, A1
Hitchcott, PK2
Higgins, GA1
Nguyen, P1
Joharchi, N1
Baumgartner, GR3
Rowen, RC2
Langan, MC3
Penetrante, ML3
Wartenberg, AA1
Nirenberg, TD1
Liepman, MR1
Silvia, LY1
Begin, AM1
Monti, PM1
Baldwin, HA5
Mathis, DA1
Yen-Koo, HC1
Tocus, EC1
Balazs, T1
Samoriski, GM2
Xie, Y1
Drummond, DC2
Turkington, D2
Rahman, MZ1
Mullin, PJ1
Jackson, P1
Radouco-Thomas, S1
Garcin, F1
Guay, D1
Marquis, PA1
Chabot, F1
Huot, J1
Chawla, S1
Forest, JC1
Martin, S1
Stewart, G1
Mendels, J1
Wasserman, TW1
Michals, TJ1
Fine, EW1
Schneider, LS1
Syapin, PJ1
Pawluczyk, S1
Gupta, AK1
Jha, BK1
Periana, RM2
Kruger, HS2
Aranko, K1
Burroughs, AK1
Morgan, MY1
Sherlock, S1
Pellow, S1
Campbell, BC1
Reid, JL1
Kaim, SC4
Whitlock, FA1
Price, J1
Browne, TR1
Penry, JK1
Gross, MM2
Mello, NK1
Mendelson, JH1
Norton, PR1
Oge, V1
Helmus, C1
Spahn, JG1
Raft, DD1
Newmark, C1
Toomey, T1
Kamei, C1
Shimomura, K1
Ueki, S1
Covi, L1
Lipman, RS1
Pattison, JH1
Derogatis, LR1
Uhlenhuth, EH1
Sampliner, R1
Iber, FL1
Goldstein, DB1
Overall, JE1
Brown, D1
Williams, JD1
Neill, LT1
Kaneto, H1
Koida, M1
Tsuchie, F1
Miyagawa, H1
Rickels, K1
Klett, CJ2
Rothfeld, B1
Caffey, EM1
Malmgren, G1
Hudson, FG1
McGowan, JM1
Renninger, ME1
Foster, CA1
Kjolstad, T1
Edgley, R1
Victor, M1
Smith, DE1
Wesson, DR1
Devenyi, P1
Hofman, G1
Kryspin-Exner, K1
Ledda, F1
Muller, DJ1
Ideström, CM1
Holmberg, G1
Wegner, ME1
Fink, DW1
Slater, J1
Chambers, JF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464]Phase 4142 participants (Anticipated)Interventional2020-07-06Recruiting
Prospective Assessment of Valproate on Ethanol Withdrawal[NCT03235531]Phase 4210 participants (Anticipated)Interventional2017-07-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

12 reviews available for chlordiazepoxide and Substance Withdrawal Syndrome

ArticleYear
Baclofen for alcohol withdrawal.
    The Cochrane database of systematic reviews, 2017, 08-20, Volume: 8

    Topics: Alcohol-Induced Disorders; Baclofen; Chlordiazepoxide; Diazepam; Ethanol; GABA Agonists; Humans; Ran

2017
Benzodiazepine withdrawal syndrome: a literature review and evaluation.
    The American journal of drug and alcohol abuse, 1982, Volume: 9, Issue:1

    Topics: Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Humans; Lorazepam

1982
The use of benzodiazepines in clinical practice.
    British journal of clinical pharmacology, 1981, Volume: 11 Suppl 1

    Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Humans; Kinetics; Lorazepa

1981
Benzodiazepine dependence.
    British journal of addiction, 1981, Volume: 76, Issue:2

    Topics: Animals; Benzodiazepines; Chlordiazepoxide; Diazepam; Disease Models, Animal; Dose-Response Relation

1981
Alcohol withdrawal: what is the benzodiazepine of choice?
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:1

    Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Chlordiazepoxide; Clinical Trials as Topic; Diazepam;

1994
The meaning and treatment of alcohol dependence.
    The British journal of psychiatry : the journal of mental science, 1975, Volume: Spec No 9

    Topics: Alcohol Withdrawal Delirium; Alcoholic Beverages; Alcoholics Anonymous; Alcoholism; Amnesia; Aversiv

1975
Selection among benzodiazepines for alcohol withdrawal.
    Southern medical journal, 1977, Volume: 70, Issue:8

    Topics: Administration, Oral; Benzodiazepines; Central Nervous System; Chlordiazepoxide; Clorazepate Dipotas

1977
Drug discrimination used to study drug withdrawal.
    NIDA research monograph, 1991, Issue:116

    Topics: Animals; Chlordiazepoxide; Discrimination Learning; Flumazenil; Pentylenetetrazole; Substance Withdr

1991
Drug therapy. Benzodiazepines (second of two parts).
    The New England journal of medicine, 1974, Dec-05, Volume: 291, Issue:23

    Topics: Affective Symptoms; Alcoholism; Analgesia; Anesthesia, General; Anesthesia, Obstetrical; Anti-Anxiet

1974
Use of beta-adrenergic receptor blocking drugs in psychiatry.
    Drugs, 1974, Volume: 8, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Anxiety; Chlordiazepoxide; Di

1974
Benzodiazepines in the treatment of epilepsy. A review.
    Epilepsia, 1973, Volume: 14, Issue:3

    Topics: Adult; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Disease Models, Animal; Eclampsia; Elec

1973
Drug use in outpatient treatment.
    The American journal of psychiatry, 1968, Volume: 124, Issue:8

    Topics: Anxiety; Barbiturates; Chlordiazepoxide; Depression; Diazepam; Educational Status; Humans; Meprobama

1968

Trials

34 trials available for chlordiazepoxide and Substance Withdrawal Syndrome

ArticleYear
A double blind randomised comparison of chlordiazepoxide and lorazepam in alcohol withdrawal.
    Asian journal of psychiatry, 2013, Volume: 6, Issue:5

    Topics: Adult; Alcoholism; Analysis of Variance; Chlordiazepoxide; Double-Blind Method; Humans; Hypnotics an

2013
A randomized, open-label, standard controlled, parallel group study of efficacy and safety of baclofen, and chlordiazepoxide in uncomplicated alcohol withdrawal syndrome.
    Biomedical journal, 2016, Volume: 39, Issue:1

    Topics: Adult; Alcohol Drinking; Baclofen; Chlordiazepoxide; Diazepam; Humans; Lorazepam; Male; Middle Aged;

2016
A randomized, double-blind comparison of lorazepam and chlordiazepoxide in patients with uncomplicated alcohol withdrawal.
    Journal of studies on alcohol and drugs, 2009, Volume: 70, Issue:3

    Topics: Adolescent; Adult; Alcohol-Induced Disorders; Alcoholism; Chlordiazepoxide; Drug Administration Sche

2009
A prospective, randomized, trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:4

    Topics: Administration, Oral; Alcohol-Related Disorders; Chlordiazepoxide; Female; GABA Modulators; Humans;

2011
A comparison of the efficacy and tolerability of clobazam and chlordiazepoxide in the treatment of acute withdrawal from alcohol in patients with primary alcoholism.
    The Journal of international medical research, 1983, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Alcoholism; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Benzodiazepinone

1983
Double-blind comparison of lorazepam and chlordiazepoxide in the treatment of the acute alcohol abstinence syndrome.
    Clinical therapeutics, 1983, Volume: 6, Issue:1

    Topics: Acute Disease; Adult; Aged; Chlordiazepoxide; Clinical Trials as Topic; Double-Blind Method; Drug Ad

1983
Tiapride and chlordiazepoxide in acute alcohol withdrawal. A controlled clinical trial.
    International journal of clinical pharmacology research, 1984, Volume: 4, Issue:5

    Topics: Adult; Benzamides; Chlordiazepoxide; Clinical Trials as Topic; Double-Blind Method; Ethanol; Female;

1984
[The addiction potential of benzodiazepines. Application of the results of treatment of alcohol withdrawal syndrome].
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Jan-24, Volume: 59, Issue:4

    Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Chlordiazepoxide; Humans; Oxazepam; Psychoses, Alcohol

1981
Individualized treatment for alcohol withdrawal. A randomized double-blind controlled trial.
    JAMA, 1994, Aug-17, Volume: 272, Issue:7

    Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Chlordiazepoxide; Double-Blind Method; Drug Administ

1994
Individualized treatment for outpatients withdrawing from alcohol.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:6

    Topics: Adult; Age Factors; Aged; Alcoholism; Ambulatory Care; Anti-Anxiety Agents; Aspartate Aminotransfera

1998
Residual effects of ethanol and chlordiazepoxide treatments for alcohol withdrawal.
    The Journal of nervous and mental disease, 1978, Volume: 166, Issue:3

    Topics: Adult; Alcoholism; Chlordiazepoxide; Electroencephalography; Ethanol; Humans; Male; Middle Aged; Psy

1978
A double blind study of chlordiazepoxide and hydroxyzine HC1 therapy in acute alcohol withdrawal utilizing chronic electromyography for tremor assessment.
    Proceedings of the Western Pharmacology Society, 1978, Volume: 21

    Topics: Alcoholism; Chlordiazepoxide; Clinical Trials as Topic; Double-Blind Method; Electromyography; Human

1978
MMPI and drug treatment in alcohol withdrawal.
    The Journal of clinical psychiatry, 1979, Volume: 40, Issue:8

    Topics: Adult; Alcoholism; Chlordiazepoxide; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Mid

1979
Control of acute alcoholic withdrawal symptoms: a comparative study of haloperidol and chlordiazepoxide.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:3

    Topics: Adult; Aged; Alcoholism; Chlordiazepoxide; Clinical Trials as Topic; Female; Haloperidol; Humans; In

1976
Slow wave sleep changes: alcohol tolerance and treatment implications.
    Advances in experimental medicine and biology, 1977, Volume: 85A

    Topics: Adult; Alcoholism; Chlordiazepoxide; Drug Tolerance; Ethanol; Humans; Male; Middle Aged; Sleep Stage

1977
A controlled trial of chlormethiazole and chlordiazepoxide in the treatment of the acute withdrawal phase of alcoholism.
    The British journal of addiction to alcohol and other drugs, 1975, Volume: 70 Suppl 1

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Chlordiazepoxide; Chlormethiazole; Clinical Trials as Topic

1975
Transdermal clonidine versus chlordiazepoxide in alcohol withdrawal: a randomized, controlled clinical trial.
    Southern medical journal, 1991, Volume: 84, Issue:3

    Topics: Administration, Cutaneous; Adult; Anxiety; Chlordiazepoxide; Clonidine; Double-Blind Method; Ethanol

1991
Chlordiazepoxide vs. methadone in opiate withdrawal: a preliminary double blind trial.
    Drug and alcohol dependence, 1989, Volume: 23, Issue:1

    Topics: Adult; Chlordiazepoxide; Clinical Trials as Topic; Double-Blind Method; Female; Heroin Dependence; H

1989
Double blind study on the efficacy and safety of tetrabamate and chlordiazepoxide in the treatment of the acute alcohol withdrawal syndrome.
    Progress in neuro-psychopharmacology & biological psychiatry, 1989, Volume: 13, Issue:1-2

    Topics: Adult; Barbiturates; Chlordiazepoxide; Clinical Trials as Topic; Double-Blind Method; Drug Combinati

1989
How should opiate withdrawal be measured?
    Drug and alcohol dependence, 1989, Volume: 24, Issue:2

    Topics: Arousal; Chlordiazepoxide; Clinical Trials as Topic; Double-Blind Method; Humans; Methadone; Nursing

1989
Halazepam in the management of acute alcohol withdrawal syndrome.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:5

    Topics: Acute Disease; Adult; Alcoholism; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chlordiaz

1985
Clonidine in heroin withdrawal syndrome: a controlled study in India.
    British journal of addiction, 1988, Volume: 83, Issue:9

    Topics: Adolescent; Adult; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Clonidine; Drug Thera

1988
Clonidine versus chlordiazepoxide in acute alcohol withdrawal: a preliminary report.
    Southern medical journal, 1988, Volume: 81, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Chlordiazepoxide; Clinical Trials as Topic; Clonidine; Doubl

1988
Clonidine vs chlordiazepoxide in the management of acute alcohol withdrawal syndrome.
    Archives of internal medicine, 1987, Volume: 147, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Blood Pressure; Chlordiazepoxide; Clinical Trials as Topic;

1987
Double-blind controlled trial of bromocriptine, chlordiazepoxide and chlormethiazole for alcohol withdrawal symptoms.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1985, Volume: 20, Issue:3

    Topics: Adult; Bromocriptine; Chlordiazepoxide; Chlormethiazole; Clinical Trials as Topic; Ethanol; Female;

1985
Prevention of delirium tremens: use of phenothiazines versus drugs cross-dependent with alcohol.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Antipsychotic Agents; Biogenic Amines; Brain Chemistry; Chlordiazepoxide; Chlorpromazine; Drug Toler

1974
Length of treatment with anxiolytic sedatives and response to their sudden withdrawal.
    Acta psychiatrica Scandinavica, 1973, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Aged; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Drug Tolerance; Female

1973
Diphenylhydantoin control of alcohol withdrawal seizures. Results of a controlled study.
    JAMA, 1974, Dec-04, Volume: 230, Issue:10

    Topics: Administration, Oral; Alcoholism; Chlordiazepoxide; Clinical Trials as Topic; Drug Evaluation; Elect

1974
Drug treatment of anxiety and depression in detoxified alcoholic patients.
    Archives of general psychiatry, 1973, Volume: 29, Issue:2

    Topics: Alcoholism; Amitriptyline; Analysis of Variance; Anxiety; Ascorbic Acid; Chlordiazepoxide; Depressio

1973
Drug therapy in alcoholism.
    The American journal of psychiatry, 1968, Volume: 125, Issue:1

    Topics: Alcoholic Intoxication; Alcoholism; Amitriptyline; Antidepressive Agents; Benactyzine; Carbamates; C

1968
Treatment of the acute alcohol withdrawal state: a comparison of four drugs.
    The American journal of psychiatry, 1969, Volume: 125, Issue:12

    Topics: Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Humans; Hydroxyzine; Middle Aged; Placeb

1969
Evaluating changes in symptoms during acute alcohol withdrawal.
    Archives of general psychiatry, 1971, Volume: 24, Issue:2

    Topics: Affect; Alcoholism; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Female; Humans; Hydr

1971
Treatment of alcohol withdrawal syndromes.
    The Medical letter on drugs and therapeutics, 1971, Mar-05, Volume: 13, Issue:5

    Topics: Chloral Hydrate; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Drug Synergism; Ethanol; Huma

1971
Comparative investigation of the effects of dixyrazine, placebo and chlordiazepoxide on alcoholics during hospital care.
    Acta neurologica et psychiatrica Belgica, 1967, Volume: 67

    Topics: Adult; Aged; Alcoholism; Chemical Phenomena; Chemistry; Chlordiazepoxide; Chronic Disease; Clinical

1967

Other Studies

118 other studies available for chlordiazepoxide and Substance Withdrawal Syndrome

ArticleYear
Association of benzodiazepines, Z-drugs, pregabalin, and melatonin with traffic accidents: A nationwide cohort and case-crossover study in Danish adults.
    Journal of psychopharmacology (Oxford, England), 2022, Volume: 36, Issue:4

    Topics: Accidents, Traffic; Adolescent; Adult; Aged; Alcoholism; Benzodiazepines; Chlordiazepoxide; Cohort S

2022
Chlordiazepoxide-induced delirium in a patient undergoing alcohol withdrawal: a case report.
    Journal of medical case reports, 2022, Jul-07, Volume: 16, Issue:1

    Topics: Adult; Alcoholism; Chlordiazepoxide; Delirium; Ethanol; Female; Humans; Substance Withdrawal Syndrom

2022
Active chlordiazepoxide metabolites in a patient needing life support after treatment of alcohol abstinence.
    Basic & clinical pharmacology & toxicology, 2020, Volume: 127, Issue:5

    Topics: Alcohol Abstinence; Alcoholism; Benzodiazepines; Chlordiazepoxide; Female; Humans; Male; Middle Aged

2020
Lorazepam versus chlordiazepoxide for the treatment of alcohol withdrawal syndrome and prevention of delirium tremens in general medicine ward patients.
    Alcohol (Fayetteville, N.Y.), 2019, Volume: 81

    Topics: Alcohol Withdrawal Delirium; Chlordiazepoxide; Ethanol; Female; Humans; Hypnotics and Sedatives; Inp

2019
Drug trials in psychiatry: methodological issues.
    Asian journal of psychiatry, 2014, Volume: 8

    Topics: Alcoholism; Chlordiazepoxide; Citalopram; Depressive Disorder; Diabetes Mellitus; Female; Humans; Hy

2014
Phenobarbital compared to benzodiazepines in alcohol withdrawal treatment: A register-based cohort study of subsequent benzodiazepine use, alcohol recidivism and mortality.
    Drug and alcohol dependence, 2016, Apr-01, Volume: 161

    Topics: Adult; Alcoholism; Benzodiazepines; Chlordiazepoxide; Cohort Studies; Ethanol; Female; GABA Modulato

2016
Distinct profiles of anxiety and dysphoria during spontaneous withdrawal from acute morphine exposure.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:10

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal;

2009
Alcohol withdrawal during hospitalization.
    The American journal of nursing, 2011, Volume: 111, Issue:1

    Topics: Central Nervous System Depressants; Chlordiazepoxide; Diazepam; Early Diagnosis; Ethanol; Humans; In

2011
Unplanned alcohol withdrawal: a survey of consecutive admissions to an acute medical unit in 2010 and 2011.
    QJM : monthly journal of the Association of Physicians, 2013, Volume: 106, Issue:1

    Topics: Acute Disease; Adult; Anti-Anxiety Agents; Chlordiazepoxide; Drug Administration Schedule; England;

2013
Elevated startle during withdrawal from acute morphine: a model of opiate withdrawal and anxiety.
    Psychopharmacology, 2004, Volume: 171, Issue:2

    Topics: Acoustic Stimulation; Acute Disease; Animals; Chlordiazepoxide; Clonidine; Disease Models, Animal; I

2004
Withdrawal reactions from chlordiazepoxide ("Librium").
    Psychopharmacologia, 1961, Feb-20, Volume: 2

    Topics: Behavior, Addictive; Chlordiazepoxide; Humans; Substance Withdrawal Syndrome; Substance-Related Diso

1961
The management of acute withdrawal symptoms of alcoholism.
    Journal of the American College of Neuropsychiatrists, 1962, Volume: 1

    Topics: Alcoholism; Chlordiazepoxide; Disease Management; Humans; Substance Withdrawal Syndrome

1962
Chlordiazepoxide in alcohol withdrawal-intramuscular effects.
    Minnesota medicine, 1963, Volume: 46

    Topics: Alcoholism; Alcohols; Chlordiazepoxide; Conduct Disorder; Humans; Minnesota; Psychoses, Substance-In

1963
COMPARATIVE CLINICAL EVALUATION OF CHLORDIAZEPOXIDE AND PROMAZINE IN TREATMENT OF ALCOHOL-WITHDRAWAL SYNDROME.
    British medical journal, 1965, Jan-09, Volume: 1, Issue:5427

    Topics: Alcohol-Induced Disorders; Alcoholism; Alcohols; Biomedical Research; Blood Pressure Determination;

1965
MANAGEMENT OF PSYCHOMOTOR AGITATION IN ACUTE ALCOHOLISM: A DOUBLE-BLIND STUDY USING CHLORDIAZEPOXIDE.
    Diseases of the nervous system, 1965, Volume: 26

    Topics: Alcoholism; Biomedical Research; Chlordiazepoxide; Depression; Depressive Disorder; Double-Blind Met

1965
Anxiolytic-like effects of the corticotropin-releasing factor1 (CRF1) antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine] administered acutely or chronically at doses occupying central CRF1 receptors
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Corticosterone; Discrimination Learning; Ma

2004
Evidence for PTZ-like cues as a function of time following treatment with chlordiazepoxide: implications for understanding tolerance and withdrawal.
    Behavioural pharmacology, 2005, Volume: 16, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Discrimination Learning; GABA Agonists; Male; Motiva

2005
Diagnosis and management of depressant drug dependence.
    The American journal of psychiatry, 1967, Volume: 123, Issue:8

    Topics: Adult; Aged; Analgesics; Barbiturates; Chlordiazepoxide; Drug Tolerance; Female; Humans; Hypnotics a

1967
Inhibition by adenosine analogs of opiate withdrawal effects.
    NIDA research monograph, 1984, Volume: 49

    Topics: 2-Chloroadenosine; Adenosine; Animals; Behavior, Animal; Chlordiazepoxide; Guinea Pigs; Humans; Ileu

1984
Choice of benzodiazepines.
    The Medical letter on drugs and therapeutics, 1981, May-01, Volume: 23, Issue:9

    Topics: Aged; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Flurazepam; Half-Life; Humans; Liver

1981
Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Acoustic Stimulation; Aminobutyrates; Animals; Chlordiazepoxide; Disea

1983
Experimental induction of benzodiazepine tolerance and physical dependence.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Animals; Benzodiazepines; Central Nervous System; Chlordiazepoxide; Depression, Chemical; Dose-Respo

1983
Experimental induction of benzodiazepine physical dependence in rodents.
    NIDA research monograph, 1982, Volume: 41

    Topics: Animals; Chlordiazepoxide; Humans; Male; Mice; Rats; Rats, Inbred Strains; Substance Withdrawal Synd

1982
Progress report of the NIDA Addiction Research Center.
    NIDA research monograph, 1982, Volume: 41

    Topics: Analgesics; Buprenorphine; Chlordiazepoxide; Clonidine; Diazepam; Humans; Morphine; National Institu

1982
[Choice of drug treatment of alcohol withdrawal symptoms in Denmark].
    Ugeskrift for laeger, 1983, Jan-24, Volume: 145, Issue:4

    Topics: Alcohol Withdrawal Delirium; Barbital; Barbiturates; Chlordiazepoxide; Denmark; Ethanol; Humans; Sub

1983
Systems of reinforcement and drug dependence.
    Drug and alcohol dependence, 1982, Volume: 10, Issue:4

    Topics: Amphetamines; Animals; Cats; Chlordiazepoxide; Cocaine; Diazepam; Drug Tolerance; Escape Reaction; E

1982
Propranolol and chlordiazepoxide effects on cardiac arrhythmias during alcohol withdrawal.
    Alcoholism, clinical and experimental research, 1980, Volume: 4, Issue:4

    Topics: Alcoholism; Arrhythmias, Cardiac; Chlordiazepoxide; Electroencephalography; Humans; Male; Propranolo

1980
Effects of acute and chronic 1,3-butanediol treatment on central nervous system function: a comparison with ethanol.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 216, Issue:2

    Topics: Animals; Behavior, Animal; Blood Pressure; Brain; Butylene Glycols; Cerebellum; Chlordiazepoxide; Do

1981
Alcohol withdrawal reactions after chronic intake of chlordiazepoxide and ethanol.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:2

    Topics: Alcoholism; Animals; Body Temperature; Chlordiazepoxide; Diet; Drug Interactions; Ethanol; Half-Life

1981
Systematic review of the benzodiazepines. Guidelines for data sheets on diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, and flurazepam. Committee on the Review of Medicines.
    British medical journal, 1980, Mar-29, Volume: 280, Issue:6218

    Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Flurazepam; Humans; Lorazepam;

1980
Effects of the CCKB antagonist L-365, 260 on benzodiazepine withdrawal-induced hypophagia in rats.
    Psychopharmacology, 1995, Volume: 118, Issue:1

    Topics: Animals; Benzodiazepinones; Chlordiazepoxide; Eating; Female; Phenylurea Compounds; Rats; Rats, Wist

1995
Different kinetics of tolerance to behavioral and electroencephalographic effects of chlordiazepoxide in the rat.
    European journal of pharmacology, 1995, Jan-24, Volume: 273, Issue:1-2

    Topics: Animals; Anticonvulsants; Behavior, Animal; Body Weight; Chlordiazepoxide; Drug Tolerance; Electroen

1995
Trends in the management of alcohol withdrawal syndrome.
    The Laryngoscope, 1995, Volume: 105, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Chlordiazepoxide;

1995
Individualized treatment of alcohol withdrawal.
    JAMA, 1995, Jan-18, Volume: 273, Issue:3

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Chlordiazepoxide; Drug Administration Schedule; Ethanol; Hu

1995
Abecarnil used to treat benzodiazepine withdrawal.
    Psychopharmacology series, 1993, Volume: 11

    Topics: Animals; Anti-Anxiety Agents; Carbolines; Chlordiazepoxide; Cues; Discrimination Learning; Flumazeni

1993
Refining the treatment of alcohol withdrawal.
    JAMA, 1994, Aug-17, Volume: 272, Issue:7

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Benzodiazepines; Chlordiazepoxide; Drug Administration Sche

1994
Chlordiazepoxide, but not bretazenil, produces acute dependence, as evidenced by disruptions in schedule-controlled behavior.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:2

    Topics: Animals; Benzodiazepinones; Chlordiazepoxide; Conditioning, Operant; Flumazenil; Male; Rats; Reinfor

1994
Conflicting evidence regarding the efficacy of ondansetron in benzodiazepine withdrawal.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Conditioning, Psychological; Discrimination Learning

1993
Evidence for a dissociation between benzodiazepine withdrawal signs.
    Neuroreport, 1993, Volume: 4, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Body Weight; Chlordiazepoxide; Male; Rats; Rats, W

1993
Effects of desipramine and alprazolam in the forced swim test in rats after long-lasting termination of chronic exposure to picrotoxin and pentylenetetrazol.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1993, Volume: 3, Issue:4

    Topics: Alprazolam; Animals; Chlordiazepoxide; Desipramine; GABA-A Receptor Antagonists; Male; Motor Activit

1993
State-dependent stimulus control: cueing attributes of ethanol "hangover" in rats.
    Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:6

    Topics: Animals; Arousal; Association Learning; Avoidance Learning; Chlordiazepoxide; Conditioning, Classica

1993
Similar effects of ethanol and flumazenil on acquisition of a shuttle-box avoidance response during withdrawal from chronic ethanol treatment.
    British journal of pharmacology, 1993, Volume: 110, Issue:2

    Topics: Animals; Avoidance Learning; Azides; Benzodiazepines; Chlordiazepoxide; Conflict, Psychological; Dos

1993
Alcohol withdrawal: a nationwide survey of inpatient treatment practices.
    Journal of general internal medicine, 1995, Volume: 10, Issue:9

    Topics: Adrenergic beta-Antagonists; Alcoholism; Barbiturates; Benzodiazepines; Chlordiazepoxide; Clonidine;

1995
Current treatment for alcohol withdrawal.
    Journal of general internal medicine, 1995, Volume: 10, Issue:9

    Topics: Alcoholism; Benzodiazepines; Chlordiazepoxide; Diazepam; Humans; Substance Withdrawal Syndrome

1995
[Benzodiazepine withdrawal syndrome in low dose dependency].
    Psychiatrische Praxis, 1996, Volume: 23, Issue:5

    Topics: Anti-Anxiety Agents; Anxiety Disorders; Chlordiazepoxide; Depressive Disorder; Diazepam; Dose-Respon

1996
Tolerance to acute anxiolysis but no withdrawal anxiogenesis in mice treated chronically with 5-HT1A receptor antagonist, WAY 100635.
    Neuroscience and biobehavioral reviews, 1998, Volume: 23, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Drug Tolerance; Exploratory Behavior; Male; Mice; Pi

1998
The alcohol withdrawal syndrome.
    Family & community health, 1979, Volume: 2, Issue:2

    Topics: Alcoholism; Chlordiazepoxide; Diazepam; Drug Tolerance; Ethanol; Hospitalization; Humans; Substance

1979
The new antiepileptic drug levetiracetam normalises chlordiazepoxide withdrawal-induced anxiety in mice.
    European journal of pharmacology, 2002, Mar-29, Volume: 439, Issue:1-3

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Chlordiazepoxide; Dose

2002
Relative effectiveness of primidone (Mysoline) and diphenylhydantoin (Dilantin) in the management of sedative withdrawal seizures.
    Annals of the New York Academy of Sciences, 1976, Volume: 273

    Topics: Antipsychotic Agents; Chlordiazepoxide; Drug Evaluation; Humans; Phenothiazines; Phenytoin; Primidon

1976
Recent advances in alcohol withdrawal states.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Nov-26, Volume: 52, Issue:23

    Topics: Adrenergic beta-Antagonists; Adult; Alcoholism; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Hum

1977
The benzodiazepines.
    American family physician, 1978, Volume: 17, Issue:5

    Topics: Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Humans; Substance Withdrawal Syndrome; Substance-Re

1978
Effects of antipsychotic and antianxiety drugs on the morphine abstinence syndrome in rats.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Body Weight; Chlordiazepoxide;

1979
The attenuation of delta 9-tetrahydrocannabinol and morphine of the quasi-morphine withdrawal syndrome in rats.
    Psychopharmacology, 1979, Mar-22, Volume: 61, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Behavior, Animal; Chlordiazepoxide; Dronabinol; Haloperidol; H

1979
Pharmacotherapy of the acute alcohol withdrawal syndrome.
    Diseases of the nervous system, 1975, Volume: 36, Issue:4

    Topics: Alcoholism; Anti-Anxiety Agents; Barbiturates; Chemical and Drug Induced Liver Injury; Chloral Hydra

1975
The use of psychoactive drugs in the long-term treatment of chronic alcoholics.
    Annals of the New York Academy of Sciences, 1975, Apr-25, Volume: 252

    Topics: Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Ch

1975
Alcoholic epilepsy. Effects of treatment on convulsions following the cessation of drinking.
    The Journal of the Medical Society of New Jersey, 1977, Volume: 74, Issue:11

    Topics: Adult; Aged; Alcoholism; Chlordiazepoxide; Female; Humans; Male; Middle Aged; Seizures; Substance Wi

1977
Biology of psychoses: past research and new frontiers.
    Southern medical journal, 1977, Volume: 70, Issue:9

    Topics: Antidepressive Agents; beta-Lipotropin; Chemistry; Chlordiazepoxide; Depression; Endorphins; History

1977
Comparative efficacy of propranolol and chlordiazepoxide in alcohol withdrawal.
    Journal of studies on alcohol, 1977, Volume: 38, Issue:11

    Topics: Adult; Alcoholism; Catecholamines; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Evaluati

1977
Absorption of oral and intramuscular chlordiazepoxide.
    European journal of clinical pharmacology, 1978, Jun-19, Volume: 13, Issue:4

    Topics: Absorption; Administration, Oral; Adult; Alcoholism; Biological Availability; Chlordiazepoxide; Deal

1978
Decline in chlordiazepoxide plasma levels during fixed-dose therapy of alcohol withdrawal.
    British journal of clinical pharmacology, 1978, Volume: 6, Issue:4

    Topics: Alcoholism; Chlordiazepoxide; Humans; Substance Withdrawal Syndrome; Time Factors

1978
Neuroendocrine correlates of clinical response during withdrawal from chlordiazepoxide.
    Communications in psychopharmacology, 1978, Volume: 2, Issue:3

    Topics: Anxiety Disorders; Chlordiazepoxide; Growth Hormone; Humans; Hydrocortisone; Male; Middle Aged; Prol

1978
Alcohol intoxication and the alcohol withdrawal syndrome.
    Postgraduate medicine, 1978, Volume: 64, Issue:6

    Topics: Alcoholic Intoxication; Alcoholism; Benzodiazepines; Chlordiazepoxide; Hallucinations; Humans; Pheny

1978
Chlordiazepoxide: long-term use in alcoholism.
    Annals of the New York Academy of Sciences, 1976, Volume: 273

    Topics: Alcoholism; Chlordiazepoxide; Drug Evaluation; Humans; Long-Term Care; Substance Withdrawal Syndrome

1976
Thioridazine HC1 Vs. chlordiazepoxide HC1 in controlling symptoms attributable to alcohol withdrawal.
    Diseases of the nervous system, 1977, Volume: 38, Issue:3

    Topics: Adult; Aged; Alcoholism; Chlordiazepoxide; Drug Evaluation; Female; Humans; Male; Middle Aged; Psych

1977
Enhancement of alcohol withdrawal convulsions in mice by haloperidol.
    Clinical toxicology, 1976, Volume: 9, Issue:3

    Topics: Animals; Chlordiazepoxide; Ethanol; Haloperidol; Humans; Mice; Seizures; Substance Withdrawal Syndro

1976
Possible role of tetrahydroisoquinoline alkaloids in postalcohol intoxication states.
    Annals of the New York Academy of Sciences, 1976, Volume: 273

    Topics: Alcoholic Intoxication; Alcoholism; Animals; Brain; Catecholamines; Chlordiazepoxide; Dopamine; Huma

1976
Effects of alcohol ingestion and abstinence on slow wave sleep of alcoholics.
    Advances in experimental medicine and biology, 1975, Volume: 59

    Topics: Adult; Alcoholism; Analysis of Variance; Chlordiazepoxide; Electroencephalography; Ethanol; Humans;

1975
Chloriazepoxide withdrawal in the neonate.
    American journal of obstetrics and gynecology, 1976, Jan-15, Volume: 124, Issue:2

    Topics: Adult; Affective Symptoms; Chlordiazepoxide; Diseases in Twins; Female; Humans; Infant, Newborn; Inf

1976
Evaluation of anxiolytic action of ondansetron in rats during withdrawal from chronic chlordiazepoxide.
    Annals of the New York Academy of Sciences, 1992, Jun-28, Volume: 654

    Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Flumazenil; Imidazoles; Learning; Male; Ondansetron;

1992
Effects of the 5-HT3 antagonist ondansetron on benzodiazepine-induced operant behavioural dependence in rats.
    Psychopharmacology, 1992, Volume: 109, Issue:4

    Topics: Animals; Chlordiazepoxide; Conditioning, Operant; Female; Ondansetron; Rats; Rats, Wistar; Reinforce

1992
Tolerance, cross-tolerance and withdrawal in rats made dependent on diazepam.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2

    Topics: Animals; Chlordiazepoxide; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Drug

1992
Effects of ritanserin and chlordiazepoxide on sleep-wakefulness alterations in rats following chronic cocaine treatment.
    Psychopharmacology, 1992, Volume: 108, Issue:3

    Topics: Animals; Chlordiazepoxide; Cocaine; Male; Rats; Rats, Inbred Strains; Ritanserin; Sleep; Sleep, REM;

1992
Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:1

    Topics: Animals; Anxiety; Baclofen; Chlordiazepoxide; Diazepam; Ethanol; Flumazenil; Interpersonal Relations

1992
Effects of 5-HT3 receptor antagonists on behavioural measures of naloxone-precipitated opioid withdrawal.
    Psychopharmacology, 1991, Volume: 105, Issue:3

    Topics: Animals; Behavior, Animal; Chlordiazepoxide; Conditioning, Operant; Drug Implants; Imidazoles; Male;

1991
Effects of the 5-HT3 antagonist GR38032F (ondansetron) on benzodiazepine withdrawal in rats.
    European journal of pharmacology, 1990, Aug-28, Volume: 185, Issue:2-3

    Topics: Animals; Anti-Anxiety Agents; Body Weight; Chlordiazepoxide; Dose-Response Relationship, Drug; Eatin

1990
The ability of chlordiazepoxide to maintain ethanol tolerance and dependence.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:2

    Topics: Animals; Body Temperature; Body Weight; Chlordiazepoxide; Diet; Drug Tolerance; Ethanol; Flumazenil;

1991
Partial cross-dependence on ethanol in mice dependent on chlordiazepoxide.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:2

    Topics: Animals; Chlordiazepoxide; Ethanol; Flumazenil; Generalization, Stimulus; Male; Mice; Mice, Inbred C

1990
Detoxification of alcoholics: improving care by symptom-triggered sedation.
    Alcoholism, clinical and experimental research, 1990, Volume: 14, Issue:1

    Topics: Alcoholism; Chlordiazepoxide; Humans; Male; Substance Withdrawal Syndrome

1990
Flumazenil prevents the development of chlordiazepoxide withdrawal in rats tested in the social interaction test of anxiety.
    Psychopharmacology, 1989, Volume: 97, Issue:3

    Topics: Animals; Anxiety; Chlordiazepoxide; Flumazenil; Interpersonal Relations; Male; Motor Activity; Rats;

1989
A liquid diet model of chlordiazepoxide dependence in mice.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:4

    Topics: Animals; Chlordiazepoxide; Diet; Disease Models, Animal; Drinking; Flumazenil; Male; Mice; Mice, Inb

1989
Withdrawal from benzodiazepine dependence as a discriminative stimulus.
    NIDA research monograph, 1989, Volume: 95

    Topics: Animals; Chlordiazepoxide; Cocaine; Discrimination Learning; Flumazenil; Pentylenetetrazole; Rats; S

1989
The effects of chronic treatment and withdrawal of CNS depressants on aggressive behavior.
    Toxicology and industrial health, 1989, Volume: 5, Issue:6

    Topics: Aggression; Animals; Behavior, Animal; Chlordiazepoxide; Dose-Response Relationship, Drug; Dronabino

1989
Effects of buspirone in the benzodiazepine dependent rat.
    NIDA research monograph, 1989, Volume: 95

    Topics: Animals; Anti-Anxiety Agents; Arousal; Buspirone; Chlordiazepoxide; Dose-Response Relationship, Drug

1989
Evidence that the increased anxiety detected in the elevated plus-maze during chlordiazepoxide withdrawal is not due to enhanced noradrenergic activity.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:4

    Topics: Animals; Anxiety; Chlordiazepoxide; Clonidine; Learning; Male; Norepinephrine; Propranolol; Rats; Ra

1989
Reversal of increased anxiety during benzodiazepine withdrawal: evidence for an anxiogenic endogenous ligand for the benzodiazepine receptor.
    Brain research bulletin, 1988, Volume: 20, Issue:5

    Topics: Animals; Anxiety; Behavior, Animal; Chlordiazepoxide; Flumazenil; Male; Rats; Receptors, GABA-A; Sub

1988
Flumazenil: a possible treatment for benzodiazepine withdrawal anxiety.
    Lancet (London, England), 1987, Jul-11, Volume: 2, Issue:8550

    Topics: Animals; Anxiety; Benzodiazepines; Chlordiazepoxide; Flumazenil; Rats; Substance Withdrawal Syndrome

1987
Seizures following triazolam withdrawal despite benzodiazepine treatment.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:10

    Topics: Anti-Anxiety Agents; Anxiety Disorders; Chlordiazepoxide; Diazepam; Humans; Male; Middle Aged; Recep

1987
Acute chlordiazepoxide dependence in the rat: comparisons to chronic.
    NIDA research monograph, 1986, Volume: 67

    Topics: Animals; Chlordiazepoxide; Drug Administration Schedule; Male; Rats; Rats, Inbred Strains; Substance

1986
Pharmacologic characterization of acute chlordiazepoxide dependence in the rat.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: Animals; Behavior, Animal; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Interactions; Dr

1986
Ethanol and chlordiazepoxide cross-dependence.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1987, Volume: 1

    Topics: Alcoholism; Animals; Chlordiazepoxide; Flumazenil; Male; Mice; Mice, Inbred C57BL; Substance Withdra

1987
Anxiogenic effects in benzodiazepine withdrawal are linked to the development of tolerance.
    Brain research bulletin, 1987, Volume: 19, Issue:5

    Topics: Animals; Anxiety; Behavior, Animal; Benzodiazepines; Chlordiazepoxide; Drug Tolerance; Injections, I

1987
Chlordiazepoxide enhances the anxiogenic action of CGS 8216 in the social interaction test: evidence for benzodiazepine withdrawal?
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:1

    Topics: Animals; Anxiety; Benzodiazepinones; Carbolines; Chlordiazepoxide; Flumazenil; Humans; Male; Pyrazol

1985
Regimen for the control of blood pressure and symptoms during clonidine withdrawal.
    International journal of clinical pharmacology research, 1985, Volume: 5, Issue:4

    Topics: Adult; Aged; Atenolol; Blood Pressure; Chlordiazepoxide; Clonidine; Female; Heart Rate; Humans; Hype

1985
Drug therapy in alcoholism.
    Current psychiatric therapies, 1970, Volume: 10

    Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepox

1970
Behavioral studies of sleep patterns in alcoholics during intoxication and withdrawal.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:1

    Topics: Adult; Alcohol Drinking; Alcoholism; Chlordiazepoxide; Ethanol; Hallucinations; Humans; Hypnotics an

1970
The effects of drugs on barbiturate withdrawal convulsions in the rat.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:10

    Topics: Animals; Barbiturates; Chlordiazepoxide; Chlorpromazine; Ethanol; Ethosuximide; Female; Humans; Hydr

1970
Drug therapy in alcoholism. It is especially important in the prevention of such complications as seizures, DT's, Wernicke's encephalopathy, or polyneuritis.
    IMJ. Illinois medical journal, 1971, Volume: 139, Issue:6

    Topics: Alcoholism; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Diazepam; Disulfiram; Humans; Hydroxy

1971
Delirium tremens in head and neck surgery.
    The Laryngoscope, 1974, Volume: 84, Issue:9

    Topics: Aged; Alcohol Withdrawal Delirium; Chlordiazepoxide; Diazepam; Humans; Laryngeal Neoplasms; Male; Mi

1974
The organic brain syndrome.
    American family physician, 1974, Volume: 10, Issue:5

    Topics: Alcoholic Intoxication; Attention; Chlordiazepoxide; Delirium; Haloperidol; Humans; Hydrocephalus; M

1974
Significance of withdrawal jumping response in predicting physical dependence in mice.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imip

1973
An animal model for testing effects of drugs on alcohol withdrawal reactions.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 183, Issue:1

    Topics: Animals; Ataxia; Barbiturates; Chlordiazepoxide; Chlormethiazole; Diazepam; Ethanol; Humans; Male; M

1972
Prevention of alcohol withdrawal seizures: the roles of diphenylhydantoin and chlordiazepoxide.
    The American journal of psychiatry, 1973, Volume: 130, Issue:12

    Topics: Alcoholism; Anticonvulsants; Chlordiazepoxide; Electroencephalography; Ethanol; Humans; Neurons; Phe

1973
[Screening procedure for barbital type physical dependence liability of psychotropic drugs in mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:5

    Topics: Amitriptyline; Animals; Barbiturates; Behavior, Animal; Benzazepines; Benzodiazepinones; Body Weight

1973
Grand-mal seizures in two patients in acute alcohol withdrawal after treatment with hydroxyzine.
    Quarterly journal of studies on alcohol, 1967, Volume: 28, Issue:4

    Topics: Alcoholism; Anticonvulsants; Chlordiazepoxide; Epilepsy, Tonic-Clonic; Humans; Hydroxyzine; Injectio

1967
Experience with chlormethiazole.
    Acta psychiatrica Scandinavica. Supplementum, 1966, Volume: 192

    Topics: Chlordiazepoxide; Chlormethiazole; Humans; Hypnotics and Sedatives; Male; Psychoses, Alcoholic; Subs

1966
Diazepam, nitrazepam and the N.H.S.
    The Medical journal of Australia, 1970, Jan-24, Volume: 1, Issue:4

    Topics: Chlordiazepoxide; Diazepam; Humans; Substance Withdrawal Syndrome; Substance-Related Disorders

1970
The alcohol withdrawal syndrome: theory and practice.
    Postgraduate medicine, 1970, Volume: 47, Issue:4

    Topics: Alcoholism; Chlordiazepoxide; Humans; Psychoses, Alcoholic; Substance Withdrawal Syndrome

1970
A new method for treatment of barbiturate dependence.
    JAMA, 1970, Jul-13, Volume: 213, Issue:2

    Topics: Barbiturates; Chlordiazepoxide; Diazepam; Heroin; Humans; Meprobamate; Pentobarbital; Phenobarbital;

1970
The treatment of acute alcohol intoxication and withdrawal.
    Current psychiatric therapies, 1970, Volume: 10

    Topics: Acute Disease; Adult; Alcoholic Intoxication; Alcoholism; Chlordiazepoxide; Chlormethiazole; Ethanol

1970
Optimal therapy of the alcohol withdrawal state.
    Current psychiatric therapies, 1970, Volume: 10

    Topics: Adult; Chlordiazepoxide; Chlorpromazine; Electrolytes; Female; Humans; Hydroxyzine; Male; Paraldehyd

1970
[Drug dependence and addiction among patients of the Vienna Psychiatric-Neurological University Hospital with special reference to psychotropic drugs].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Analgesics; Antidepressive Agents; Antitussive Agents; Austria; Barbiturates; Cannabis; Chlordiazepo

1970
[Acute chlordiazepoxide poisoning in a drug addict, followed by withdrawal syndrome].
    La Clinica terapeutica, 1968, Jan-31, Volume: 44, Issue:2

    Topics: Adult; Chlordiazepoxide; Humans; Male; Morphine Dependence; Substance Withdrawal Syndrome

1968
A comparison of three approaches to alcohol-withdrawal states.
    Southern medical journal, 1969, Volume: 62, Issue:4

    Topics: Adult; Alcoholism; Chloral Hydrate; Chlordiazepoxide; Chlorpromazine; Female; Humans; Male; Paraldeh

1969
[Therapy of anxiety, mental anguish and sleeplessness. 4. Drug abuse and accidents].
    Lakartidningen, 1969, Mar-17, Volume: 66

    Topics: Accidents, Traffic; Barbiturates; Chlordiazepoxide; Chlormethiazole; Diazepam; Drug Synergism; Ethan

1969
[Therapy of anxiety, mental anguish and sleeplessness. 5. Abuse of diazepam?].
    Lakartidningen, 1969, Mar-17, Volume: 66

    Topics: Chlordiazepoxide; Diazepam; Humans; Meprobamate; Substance Withdrawal Syndrome; Substance-Related Di

1969
Chlordiazepoxide (librium) compared with meprobamate and promazine (prozine) for the withdrawal symptoms of acute alcoholism.
    Wisconsin medical journal, 1965, Volume: 64, Issue:11

    Topics: Alcoholic Intoxication; Alcoholism; Chlordiazepoxide; Humans; Male; Meprobamate; Promazine; Substanc

1965
Suspected dependence on chlordiazepoxide hydrochloride (Librium).
    Canadian Medical Association journal, 1966, Aug-27, Volume: 95, Issue:9

    Topics: Adult; Chlordiazepoxide; Female; Humans; Substance Withdrawal Syndrome; Substance-Related Disorders

1966
Management of acute alcohol withdrawal symptoms.
    Maryland state medical journal, 1966, Volume: 15, Issue:6

    Topics: Alcoholism; Chloral Hydrate; Chlordiazepoxide; Humans; Substance Withdrawal Syndrome

1966