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chlordiazepoxide and Hepatitis, Alcoholic

chlordiazepoxide has been researched along with Hepatitis, Alcoholic in 2 studies

Chlordiazepoxide: An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
chlordiazepoxide : A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Research Excerpts

ExcerptRelevanceReference
"The clearance of chlordiazepoxide from the systemic circulation was studied in 20 subjects which included 15 patients with alcoholic hepatitis and 5 normal volunteers."7.66Clinical pharmacokinetics of chlordiazepoxide in patients with alcoholic hepatitis. ( Mendenhall, CL; Morgan, DD; Robinson, JD, 1981)
"The clearance of chlordiazepoxide from the systemic circulation was studied in 20 subjects which included 15 patients with alcoholic hepatitis and 5 normal volunteers."3.66Clinical pharmacokinetics of chlordiazepoxide in patients with alcoholic hepatitis. ( Mendenhall, CL; Morgan, DD; Robinson, JD, 1981)
"Bromocriptine was ineffective in treating withdrawal symptoms, whilst chlormethiazole and chlordiazepoxide were equally effective."2.66Double-blind controlled trial of bromocriptine, chlordiazepoxide and chlormethiazole for alcohol withdrawal symptoms. ( Burroughs, AK; Morgan, MY; Sherlock, S, 1985)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morgan, DD1
Robinson, JD1
Mendenhall, CL1
Burroughs, AK1
Morgan, MY1
Sherlock, S1

Trials

1 trial available for chlordiazepoxide and Hepatitis, Alcoholic

ArticleYear
Double-blind controlled trial of bromocriptine, chlordiazepoxide and chlormethiazole for alcohol withdrawal symptoms.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1985, Volume: 20, Issue:3

    Topics: Adult; Bromocriptine; Chlordiazepoxide; Chlormethiazole; Clinical Trials as Topic; Ethanol; Female;

1985

Other Studies

1 other study available for chlordiazepoxide and Hepatitis, Alcoholic

ArticleYear
Clinical pharmacokinetics of chlordiazepoxide in patients with alcoholic hepatitis.
    European journal of clinical pharmacology, 1981, Volume: 19, Issue:4

    Topics: Adult; Chlordiazepoxide; Half-Life; Hepatitis, Alcoholic; Humans; Kinetics; Metabolic Clearance Rate

1981
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