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chlordiazepoxide and Gastric Ulcer

chlordiazepoxide has been researched along with Gastric Ulcer in 17 studies

Chlordiazepoxide: An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
chlordiazepoxide : A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.

Research Excerpts

ExcerptRelevanceReference
" The effects of CGS 9896, a partial benzodiazepine agonist, and chlordiazepoxide, a full benzodiazepine agonist, on stress-induced gastric ulcers as well as blood glucose were compared."3.68Effect of CGS 9896 on stress-induced gastric ulcer in rat. ( Karim, KH; Najim, RA, 1990)
"Bilateral intra-amygdalar (i/am) microinjections of TRH (1 and 10 micrograms) and physostigmine (10 micrograms) into the central nucleus (CEA) aggravated cold restraint stress (3 hr at 4 degrees C) induced gastric ulcer formation in rats, whereas atropine (1, 5 and 10 micrograms) attenuated this phenomenon."3.68Effects of intra-amygdalar thyrotropin releasing hormone (TRH) and its antagonism by atropine and benzodiazepines during stress ulcer formation in rats. ( Henke, PG; Ray, A; Sullivan, RM, 1990)
"The effects of bilateral microinjections of chlordiazepoxide and GABA into the central amygdalar nucleus on gastric ulcer formation induced by cold-restraint were examined in chronically implanted Wistar rats."3.67The GABA/benzodiazepine receptor complex in the central amygdalar nucleus and stress ulcers in rats. ( Hebert, MA; Henke, PG; Ray, A; Sullivan, RM; Trimper, JM, 1989)
"The effects of a benzodiazepine receptor inverse agonist (FG 7142) on gastric ulcer formation were studied in restrained rats."3.67A benzodiazepine receptor inverse agonist inhibits stress-induced ulcer formation. ( Ginter, H; Skolnick, P; Trullas, R, 1987)
"Intraperitoneal injections of chlordiazepoxide in rats attenuated the severity of stomach ulcers induced by a single restraint session."3.67Chlordiazepoxide and stress tolerance in rats. ( Henke, PG, 1987)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199014 (82.35)18.7374
1990's2 (11.76)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HAOT, J1
DJAHANGUIRI, B1
RICHELLE, M1
Blum, JE1
Hürlimann, A1
Mercier, J1
Lumbroso, S1
Bleger, G1
File, SE1
Pearce, JB1
Mediratta, PK1
Sharma, KK1
Rana, J1
Dairman, WM1
Juhasz, L1
Najim, RA1
Karim, KH1
Ray, A2
Henke, PG3
Sullivan, RM2
Hebert, MA1
Trimper, JM1
Trullas, R1
Ginter, H1
Skolnick, P1
Dasgupta, SR1
Mukherjee, BP1
Rosenberg, A1
Gayral, LF1
Möllmann, H2
Egbers, HJ2

Other Studies

17 other studies available for chlordiazepoxide and Gastric Ulcer

ArticleYear
[PROTECTIVE ACTION OF CHLORDIAZEPOXIDE ON RESTRAINT ULCER IN THE RAT].
    Archives internationales de pharmacodynamie et de therapie, 1964, Apr-01, Volume: 148

    Topics: Chlordiazepoxide; Pharmacology; Rats; Research; Stomach Ulcer; Stress, Physiological; Ulcer

1964
[On the influence of immobilization-triggered stomach ulcers of psychopharmaceuticals. Strengthening of the protective effect of amitryptyline with chlordiazepoxide].
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 15, Issue:6

    Topics: Amitriptyline; Animals; Chlordiazepoxide; Drug Synergism; Immobilization; Rats; Stomach Ulcer

1966
[Influence exerted by 1,3-dihydro-7-nitro-5-phenyl-2H-1,4 benzodiazepine-2-one (Mogadon) on stress ulcer in albino rats and mice].
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 167, Issue:1

    Topics: Animals; Chlordiazepoxide; Hypnotics and Sedatives; Mice; Rats; Stomach Ulcer; Stress, Physiological

1967
[Long term medical treatment of ulcer excluding acute attacks].
    Medecine & chirurgie digestives, 1980, Volume: 9, Issue:5

    Topics: Chlordiazepoxide; Cimetidine; Drug Combinations; Duodenal Ulcer; Guanidines; Humans; Quinuclidines;

1980
Benzodiazepines reduce gastric ulcers induced in rats by stress.
    British journal of pharmacology, 1981, Volume: 74, Issue:3

    Topics: Animals; Atropine; Benzodiazepines; Chlordiazepoxide; Cimetidine; Female; Gastric Acid; Gastric Muco

1981
Development of differential tolerance to the sedative and anti-stress effects of benzodiazepines.
    Indian journal of physiology and pharmacology, 2001, Volume: 45, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Chlordiazepoxide; Diazepam; Drug Tolerance; Gastric M

2001
A study in mice of benzodiazephine-anticholinergic interaction: protection against restraint-immersion and forced exertion-induced gastric mucosal erosion.
    Pharmacology, 1978, Volume: 17, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Drug Eva

1978
Effect of CGS 9896 on stress-induced gastric ulcer in rat.
    Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:2

    Topics: Animals; Benzodiazepines; Chlordiazepoxide; Cold Temperature; Drug Therapy, Combination; Flumazenil;

1990
Effects of intra-amygdalar thyrotropin releasing hormone (TRH) and its antagonism by atropine and benzodiazepines during stress ulcer formation in rats.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:3

    Topics: Amygdala; Animals; Atropine; Chlordiazepoxide; Drug Interactions; Male; Midazolam; Physostigmine; Ra

1990
The GABA/benzodiazepine receptor complex in the central amygdalar nucleus and stress ulcers in rats.
    Behavioral and neural biology, 1989, Volume: 51, Issue:2

    Topics: Amygdala; Animals; Arousal; Chlordiazepoxide; Dose-Response Relationship, Drug; Flumazenil; Male; Ra

1989
A benzodiazepine receptor inverse agonist inhibits stress-induced ulcer formation.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:1

    Topics: Animals; Carbolines; Chlordiazepoxide; Male; Propranolol; Rats; Rats, Inbred Strains; Receptors, GAB

1987
Chlordiazepoxide and stress tolerance in rats.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:3

    Topics: Adaptation, Physiological; Animals; Chlordiazepoxide; Male; Rats; Rats, Inbred Strains; Restraint, P

1987
Effect of chlordiazepoxide on stomach ulcers in rabbit induced by stress.
    Nature, 1967, Sep-09, Volume: 215, Issue:5106

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Chlordiazepoxide; Male; Rabbits; Stom

1967
Production of gastric lesions in rats by combined cold and electrostress.
    The American journal of digestive diseases, 1967, Volume: 12, Issue:11

    Topics: Animals; Atropine; Barbiturates; Chlordiazepoxide; Chlorpromazine; Cold Temperature; Electroshock; E

1967
[Tranquillisers in the treatment of psychosomatic diseases].
    Munchener medizinische Wochenschrift (1950), 1972, Jun-23, Volume: 114, Issue:25

    Topics: Amitriptyline; Asthma; Benzazepines; Benzene Derivatives; Chlordiazepoxide; Colitis, Ulcerative; Dru

1972
[Comparative study on the influence of psychotropic agents on stress induced lesions of the gastric mucosa].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:4

    Topics: Administration, Oral; Amitriptyline; Animals; Chlordiazepoxide; Female; Fluphenazine; Gastric Mucosa

1972
A comparative investigation of the effects of specific psychotropic agents on immobilization-induced ulcer.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:3

    Topics: Amitriptyline; Animals; Central Nervous System; Chlordiazepoxide; Drug Synergism; Female; Fluphenazi

1971