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chlordiazepoxide and Depressive Disorder

chlordiazepoxide has been researched along with Depressive Disorder in 35 studies

Chlordiazepoxide: An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
chlordiazepoxide : A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.

Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Research Excerpts

ExcerptRelevanceReference
" Also, they displayed higher levels of blood serum corticosterone, as well as decreased body weight."3.88Vicarious Social Defeat Stress Induces Depression-Related Outcomes in Female Mice. ( Alipio, JB; Braren, SH; Castillo, SA; Flores-Ramirez, FJ; Garcia-Carachure, I; Hernandez, MA; Iñiguez, SD; Lobo, MK; Riggs, LM; Sanchez, DO; Serrano, PA, 2018)
"Chlordiazepoxide-treated patients generally did significantly better on sleep difficulty but significantly worse on anger-hostility and interpersonal sensitivity than did imipramine- or placebo-treated patients."2.66Imipramine and chlordiazepoxide in depressive and anxiety disorders. I. Efficacy in depressed outpatients. ( Covi, L; Downing, R; Faden, V; Kahn, RJ; Lasseter, VK; Lipman, RS; McNair, DM; Rickels, K, 1986)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199031 (88.57)18.7374
1990's2 (5.71)18.2507
2000's0 (0.00)29.6817
2010's2 (5.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iñiguez, SD1
Flores-Ramirez, FJ1
Riggs, LM1
Alipio, JB1
Garcia-Carachure, I1
Hernandez, MA1
Sanchez, DO1
Lobo, MK1
Serrano, PA1
Braren, SH1
Castillo, SA1
Prakash, S1
Mandal, P1
TORTORA, E1
FELDMAN, PE1
HOFFER, A1
BADER, A1
LEONARD, JW1
GIFFORD, RW1
WILLIAMS, GH1
ACHTE, KA1
ROSE, JT1
FOURNIER, A1
CROCQ, L1
RIGAL, J1
AUBIN, JP1
ABDOU, FA1
FORREST, AD1
GOLD, RL1
DRIBBEN, IS1
MELDMAN, MJ1
FELLNER, CH1
GILLINGHAM, FJ1
SMYTHIES, JR1
MANS, J1
SENES, M1
AINSLIE, JD1
JONES, MB1
STIEFEL, JR1
KISSEN, MD1
HOVE, H1
MICHAUX, L1
DUCHE, DJ1
SAKURAI, T1
NISHISONO, M1
Targum, SD1
Wheadon, DE1
Chastek, CT1
McCabe, WJ1
Advani, MT1
Downing, RW1
Rickels, K2
Dixon, R1
Cohen, J1
Tsaras, G1
Ambrus, J1
Dimitriou, EC1
Logothetis, JA1
Paschalidou, M1
Petty, F1
Trivedi, MH1
Fulton, M1
Rush, AJ1
Thomas, H1
Mörchen, G1
Lipman, RS1
Covi, L1
McNair, DM1
Downing, R1
Kahn, RJ1
Lasseter, VK1
Faden, V1
Scharf, MB1
Hirschowitz, J1
Zemlan, FP1
Lichstein, M1
Woods, M1
Welner, J1
James, RT1
Dean, BC1
Dackis, CA1
Gold, MS1
Pottash, AL1
Sweeney, DR1
Goethe, JW1
Edelman, SL1

Reviews

1 review available for chlordiazepoxide and Depressive Disorder

ArticleYear
Benzodiazepines as antidepressants: does GABA play a role in depression?
    Biological psychiatry, 1995, Nov-01, Volume: 38, Issue:9

    Topics: Alprazolam; Antidepressive Agents; Benzodiazepines; Chlordiazepoxide; Depressive Disorder; Diazepam;

1995

Trials

6 trials available for chlordiazepoxide and Depressive Disorder

ArticleYear
Physician prognosis in relationship to drug and placebo response in anxious and depressed psychiatric outpatients.
    The Journal of nervous and mental disease, 1983, Volume: 171, Issue:3

    Topics: Adult; Ambulatory Care; Amitriptyline; Anxiety Disorders; Attitude of Health Personnel; Chlordiazepo

1983
[Comparative clinical study of the association of chlordiazepoxide-amitriptyline and maprotiline in patients suffering from depression with anxiety components].
    Revue medicale de la Suisse romande, 1981, Volume: 101, Issue:6

    Topics: Adult; Aged; Amitriptyline; Anthracenes; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depres

1981
A double blind comparative study of mianserin and a fixed combination of amitriptyline plus chlordiazepoxide.
    Advances in biochemical psychopharmacology, 1982, Volume: 32

    Topics: Adolescent; Adult; Aged; Amitriptyline; Chlordiazepoxide; Clinical Trials as Topic; Depressive Disor

1982
Imipramine and chlordiazepoxide in depressive and anxiety disorders. I. Efficacy in depressed outpatients.
    Archives of general psychiatry, 1986, Volume: 43, Issue:1

    Topics: Adult; Anger; Cardiovascular System; Chlordiazepoxide; Clinical Trials as Topic; Depressive Disorder

1986
Comparative effects of limbitrol and amitriptyline on sleep efficiency and architecture.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:12

    Topics: Adult; Amitriptyline; Anxiety Disorders; Chlordiazepoxide; Clinical Trials as Topic; Depressive Diso

1986
Comparison of limbitrol (chlordiazepoxide/amitriptyline) and amitriptyline alone as a single night-time dose for the treatment of depression with anxiety.
    The Journal of international medical research, 1985, Volume: 13, Issue:2

    Topics: Adult; Aged; Amitriptyline; Chlordiazepoxide; Circadian Rhythm; Clinical Trials as Topic; Depressive

1985

Other Studies

28 other studies available for chlordiazepoxide and Depressive Disorder

ArticleYear
Vicarious Social Defeat Stress Induces Depression-Related Outcomes in Female Mice.
    Biological psychiatry, 2018, Jan-01, Volume: 83, Issue:1

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Body Weight; Chlordiazepoxide; Corticosterone; D

2018
Drug trials in psychiatry: methodological issues.
    Asian journal of psychiatry, 2014, Volume: 8

    Topics: Alcoholism; Chlordiazepoxide; Citalopram; Depressive Disorder; Diabetes Mellitus; Female; Humans; Hy

2014
[Clinical experience with the use of methaminodiazepoxide (MADO) of the delayed type in depressive-anxious syndromes].
    Gazzetta medica italiana, 1961, Volume: 120

    Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Depressive Disorder; Syndrome; Tranquilizing Agents

1961
An analysis of the efficacy of diazepam.
    Journal of neuropsychiatry, 1962, Volume: 3(Suppl 1)

    Topics: Chlordiazepoxide; Depression; Depressive Disorder; Diazepam; Schizophrenia; Tranquilizing Agents

1962
Lack of potentiation by chlordiazepoxide (Librium) of depression or excitation due to alcohol.
    Canadian Medical Association journal, 1962, Oct-27, Volume: 87

    Topics: Adult; Alcoholic Beverages; Canada; Chlordiazepoxide; Depression; Depressive Disorder; Double-Blind

1962
[On anxiety-easing medication in the general practice].
    Praxis, 1963, Jan-24, Volume: 52

    Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Depression; Depressive Disorder; Family Practice; Huma

1963
TRANYLCYPROMINE SULFATE THERAPY. OCCURRENCE OF SEVERE PAROXYSMAL HEADACHE.
    JAMA, 1964, Mar-21, Volume: 187

    Topics: Chlordiazepoxide; Depression; Depressive Disorder; Headache; Toxicology; Tranylcypromine

1964
[THE PROBLEM OF SUICIDE].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1963, Volume: 17

    Topics: Alcoholism; Antidepressive Agents; Chlordiazepoxide; Counseling; Depression; Depressive Disorder; Fi

1963
PHENOXYPROPAZINE AND CHLORDIAZEPOXIDE IN DEPRESSION.
    The American journal of psychiatry, 1964, Volume: 120

    Topics: Antidepressive Agents; Chlordiazepoxide; Depression; Depressive Disorder; Monoamine Oxidase Inhibito

1964
[THE ASSOCIATION OF IPROCLOZIDE AND CHLORDIAZEPOXIDE IN THE TREATMENT OF DEPRESSIVE STATES (APROPOS OF 61 CASES)].
    Annales medico-psychologiques, 1964, Volume: 122

    Topics: Chlordiazepoxide; Depression; Depressive Disorder; Glycolates; Humans; Monoamine Oxidase Inhibitors

1964
ELAVIL-LIBRIUM COMBINATION.
    The American journal of psychiatry, 1964, Volume: 120

    Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Depression; Depressive Disorder; Toxicology

1964
DRUGS FOR DEPRESSION.
    British medical journal, 1964, Sep-19, Volume: 2, Issue:5411

    Topics: Amobarbital; Antidepressive Agents; Chlordiazepoxide; Depression; Depressive Disorder; Dextroampheta

1964
DIAZEPAM THERAPY OF DEPRESSED PATIENTS.
    Journal of neuropsychiatry, 1964, Volume: 5

    Topics: Bipolar Disorder; Chlordiazepoxide; Depression; Depressive Disorder; Depressive Disorder, Major; Dia

1964
PRR STUDY NO. 3. (A METHOD FOR CONTROLLING THE ADMINISTRATION OF TRANYLCYPROMINE).
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Alcoholism; Anxiety; Anxiety Disorders; Chlordiazepoxide; Depression; Depressive Disorder; Drug Ther

1964
EARLY RECOGNITION OF DEPRESSION.
    Geriatrics, 1964, Volume: 19

    Topics: Amitriptyline; Amphetamine; Amphetamines; Barbiturates; Benactyzine; Chlordiazepoxide; Deanol; Depre

1964
A CASE OF POSTENCEPHALITIC PARKINSONISM RESPONDING TO COMBINED SURGICAL AND MEDICINAL TREATMENT.
    Lancet (London, England), 1965, Jan-23, Volume: 1, Issue:7378

    Topics: Amitriptyline; Chlordiazepoxide; Depression; Depressive Disorder; Drug Therapy; Encephalitis; Eye Mo

1965
[ISOCARBOXAZIDE; RO 5-0690 OR CHLORDIAZEPOXIDE; RO 4-0403, DERIVATIVE OF THIOXANTHENES. STUDY ON THEIR INDIVIDUAL EFFECTS AND THEIR POSSIBILITIES OF COMBINATION].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1964, Volume: 141

    Topics: Biomedical Research; Chlordiazepoxide; Chlorprothixene; Depression; Depressive Disorder; Drug Therap

1964
PRACTICAL DRUG EVALUATION METHOD: IMIPRAMINE IN DEPRESSED OUTPATIENTS.
    Archives of general psychiatry, 1965, Volume: 12

    Topics: Amobarbital; Biomedical Research; Chlordiazepoxide; Chlorpromazine; Depression; Depressive Disorder;

1965
MANAGEMENT OF PSYCHOMOTOR AGITATION IN ACUTE ALCOHOLISM: A DOUBLE-BLIND STUDY USING CHLORDIAZEPOXIDE.
    Diseases of the nervous system, 1965, Volume: 26

    Topics: Alcoholism; Biomedical Research; Chlordiazepoxide; Depression; Depressive Disorder; Double-Blind Met

1965
[Clinical influence of Librium therapy on psychiatric patients].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1962, Volume: 16

    Topics: Chlordiazepoxide; Depression; Depressive Disorder; Humans; Leadership; Neurotic Disorders; Patients;

1962
[Contribution to the symptomatic analysis of anxiety with the help of methaminodiazepoxide therapy].
    Annales medico-psychologiques, 1962, Volume: 120(1)

    Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Depression; Depressive Disorder; Tranquilizing Agents

1962
[Combined use of chlordiazepoxide (Contol) and isocarboxazid (Enerzer) in depressive states].
    No to shinkei = Brain and nerve, 1962, Volume: 14

    Topics: Antidepressive Agents; Chlordiazepoxide; Depression; Depressive Disorder; Hydrazines; Isocarboxazid;

1962
Dysregulation of hypothalamic-pituitary-adrenal axis function in depressed alcoholic patients.
    Journal of affective disorders, 1982, Volume: 4, Issue:4

    Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Chlordiazepoxide; Depressive Disorder; Dexamethasone

1982
Steady state plasma concentration profiles and therapeutic response in anxious-depressed outpatients after administration of a chlordiazepoxide-amitriptyline combination.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:2

    Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Dep

1983
[Benzodiazepine withdrawal syndrome in low dose dependency].
    Psychiatrische Praxis, 1996, Volume: 23, Issue:5

    Topics: Anti-Anxiety Agents; Anxiety Disorders; Chlordiazepoxide; Depressive Disorder; Diazepam; Dose-Respon

1996
Efficacy of imipramine and chlordiazepoxide in depressive and anxiety disorders questioned.
    Archives of general psychiatry, 1987, Volume: 44, Issue:1

    Topics: Ambulatory Care; Anxiety Disorders; Chlordiazepoxide; Depressive Disorder; Humans; Imipramine; Psych

1987
Evaluating depression in alcoholics.
    Psychiatry research, 1986, Volume: 17, Issue:2

    Topics: Adult; Alcoholism; Chlordiazepoxide; Depressive Disorder; Female; Humans; Male; Middle Aged; Psychol

1986
Chlordiazepoxide toxicity in Limbitrol overdose.
    The American journal of psychiatry, 1985, Volume: 142, Issue:6

    Topics: Adult; Amitriptyline; Chlordiazepoxide; Depressive Disorder; Drug Combinations; Humans; Male; Stress

1985